Daniel P Depledge

Affiliations

6401Division of Infection and Immunity, University College London, London, United Kingdom.

ORCID: 0000-0002-4292-0599

Publications (40)

Chromatin dynamics and the transcriptional competence of HSV-1 genomes during lytic infections.

PLoS pathogens

Avec: MiYao Hu , Daniel P Depledge , Esteban Flores Cortes , Judith Breuer , Luis M Schang

Going the Distance: Optimizing RNA-Seq Strategies for Transcriptomic Analysis of Complex Viral Genomes.

Journal of virology

Avec: Daniel P Depledge , Ian Mohr , Angus C Wilson

Single-cell transcriptomics identifies Gadd45b as a regulator of herpesvirus-reactivating neurons.

EMBO reports

Avec: Hui-Lan Hu , Kalanghad P Srinivas , Shuoshuo Wang , Moses V Chao , Timothee Lionnet , Ian Mohr , Angus C Wilson , Daniel P Depledge , Tony T Huang

Direct RNA sequencing reveals m

Nature communications

Avec: Alexander M Price , Katharina E Hayer , Alexa B R McIntyre , Nandan S Gokhale , Jonathan S Abebe , Ashley N Della Fera , Christopher E Mason , Stacy M Horner , Angus C Wilson , Daniel P Depledge , Matthew D Weitzman

Nanopore Guided Annotation of Transcriptome Architectures.

bioRxiv : the preprint server for biology

Avec: Jonathan S Abebe , Yasmine Alwie , Erik Fuhrmann , Jonas Leins , Julia Mai , Ruth Verstraten , Sabrina Schreiner , Angus C Wilson , Daniel P Depledge

Viral modulation of type II interferon increases T cell adhesion and virus spread.

bioRxiv : the preprint server for biology

Avec: Carina Jürgens , George Ssebyatika , Sarah Beyer , Nina Plückebaum , Kai A Kropp , Víctor González-Motos , Birgit Ritter , Heike Böning , Eirini Nikolouli , Paul R Kinchington , Nico Lachmann , Daniel Pearce Depledge , Thomas Krey , Abel Viejo-Borbolla

Genetic and phenotypic intrastrain variation in herpes simplex virus type 1 Glasgow strain 17 syn+-derived viruses.

The Journal of general virology

Avec: Juliet Jones , Daniel Pearce Depledge , Judith Breuer , Katja Ebert-Keel , Gillian Elliott

Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency.

Nature communications

Avec: Werner J D Ouwendijk , Daniel P Depledge , Labchan Rajbhandari , Tihana Lenac Rovis , Stipan Jonjic , Judith Breuer , Arun Venkatesan , Georges M G M Verjans , Tomohiko Sadaoka

Decoding the Architecture of the Varicella-Zoster Virus Transcriptome.

mBio

Avec: Shirley E Braspenning , Tomohiko Sadaoka , Judith Breuer , Georges M G M Verjans , Werner J D Ouwendijk , Daniel P Depledge

An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stress.

Cell reports

Avec: Letitia Thompson , Daniel P Depledge , Hannah M Burgess , Ian Mohr

Novel viral splicing events and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts.

PLoS pathogens

Avec: Alexander M Price , Robert T Steinbock , Richard Lauman , Matthew Charman , Katharina E Hayer , Namrata Kumar , Edwin Halko , Krystal K Lum , Monica Wei , Angus C Wilson , Benjamin A Garcia , Daniel P Depledge , Matthew D Weitzman

Nanopore guided annotation of transcriptome architectures.

mSystems

Avec: Jonathan S Abebe , Yasmine Alwie , Erik Fuhrmann , Jonas Leins , Julia Mai , Ruth Verstraten , Sabrina Schreiner , Angus C Wilson , Daniel P Depledge

Viral modulation of type II interferon increases T cell adhesion and virus spread.

Nature communications

Avec: Carina Jacobsen , Nina Plückebaum , George Ssebyatika , Sarah Beyer , Lucas Mendes-Monteiro , Jiayi Wang , Kai A Kropp , Víctor González-Motos , Lars Steinbrück , Birgit Ritter , Claudio Rodríguez-González , Heike Böning , Eirini Nikolouli , Paul R Kinchington , Nico Lachmann , Daniel P Depledge , Thomas Krey , Abel Viejo-Borbolla

Recurrent herpes zoster in the Shingles Prevention Study: Are second episodes caused by the same varicella-zoster virus strain?

Vaccine

Avec: Ruth Harbecke , Nancy J Jensen , Daniel P Depledge , Gary R Johnson , Mark E Ashbaugh , D Scott Schmid , Judith Breuer , Myron J Levin , Michael N Oxman

Kallikrein-Mediated Cytokeratin 10 Degradation Is Required for Varicella Zoster Virus Propagation in Skin.

The Journal of investigative dermatology

Avec: Cristina Tommasi , Clare Rogerson , Daniel P Depledge , Meleri Jones , Aishath S Naeem , Cristina Venturini , Dan Frampton , Helena J Tutill , Benjamin Way , Judith Breuer , Ryan F L O'Shaughnessy

Targeting the m

Genes & development

Avec: Hannah M Burgess , Daniel P Depledge , Letitia Thompson , Kalanghad Puthankalam Srinivas , Rebecca C Grande , Elizabeth I Vink , Jonathan S Abebe , Wesley P Blackaby , Alan Hendrick , Mark R Albertella , Tony Kouzarides , Kenneth A Stapleford , Angus C Wilson , Ian Mohr

The architecture of the simian varicella virus transcriptome.

PLoS pathogens

Avec: Shirley E Braspenning , Georges M G M Verjans , Tamana Mehraban , Ilhem Messaoudi , Daniel P Depledge , Werner J D Ouwendijk

ICTV Virus Taxonomy Profile:

The Journal of general virology

Avec: Derek Gatherer , Daniel P Depledge , Carol A Hartley , Moriah L Szpara , Paola K Vaz , Mária Benkő , Curtis R Brandt , Neil A Bryant , Akbar Dastjerdi , Andor Doszpoly , Ursula A Gompels , Naoki Inoue , Keith W Jarosinski , Rajeev Kaul , Vincent Lacoste , Peter Norberg , Francesco C Origgi , Richard J Orton , Philip E Pellett , D Scott Schmid , Stephen J Spatz , James P Stewart , Jakob Trimpert , Thomas B Waltzek , Andrew J Davison

Nanopore-Based Detection of Viral RNA Modifications.

mBio

Avec: Jonathan S Abebe , Ruth Verstraten , Daniel P Depledge

Epstein-Barr Virus-Encoded BILF1 Orthologues From Porcine Lymphotropic Herpesviruses Display Common Molecular Functionality.

Frontiers in endocrinology

Avec: Maša Mavri , Valentina Kubale , Daniel P Depledge , Jianmin Zuo , Christene A Huang , Judith Breuer , Milka Vrecl , Michael A Jarvis , Eva Jarc Jovičić , Toni Petan , Bernhard Ehlers , Mette M Rosenkilde , Katja Spiess

Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice.

Journal of virology

Avec: Werner J D Ouwendijk , Pavitra Roychoudhury , Anthony L Cunningham , Keith R Jerome , David M Koelle , Paul R Kinchington , Ian Mohr , Angus C Wilson , Georges G M G M Verjans , Daniel P Depledge

Evasion of a Human Cytomegalovirus Entry Inhibitor with Potent Cysteine Reactivity Is Concomitant with the Utilization of a Heparan Sulfate Proteoglycan-Independent Route of Entry.

Journal of virology

Avec: M J Murray , N I Bonilla-Medrano , Q L Lee , S J Oxenford , R Angell , D P Depledge , M B Reeves

Analysis of the reiteration regions (R1 to R5) of varicella-zoster virus.

Virology

Avec: Nancy J Jensen , Daniel P Depledge , Terry Fei Fan Ng , Jessica Leung , Mark Quinlivan , Kay W Radford , Jennifer Folster , Hung-Fu Tseng , Philip LaRussa , Steven J Jacobsen , Judith Breuer , D Scott Schmid

Whole genome sequencing of Herpes Simplex Virus 1 directly from human cerebrospinal fluid reveals selective constraints in neurotropic viruses.

Virus evolution

Avec: Florent Lassalle , Mathew A Beale , Tehmina Bharucha , Charlotte A Williams , Rachel J Williams , Juliana Cudini , Richard Goldstein , Tanzina Haque , Daniel P Depledge , Judith Breuer

Varicella-Zoster Virus-Genetics, Molecular Evolution and Recombination.

Current topics in microbiology and immunology

Avec: Daniel P Depledge , Judith Breuer

Histone H2A variant H2A.B is enriched in transcriptionally active HSV-1 lytic chromatin.

bioRxiv : the preprint server for biology

Avec: Esteban Flores , Sarah M Saddoris , Arryn K Owens , Rebecca Gibeault , Daniel P Depledge , Luis M Schang

tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen

Proceedings of the National Academy of Sciences of the United States of America

Avec: Jonas Krueger , Matthias Preusse , Nicolas Oswaldo Gomez , Yannick Noah Frommeyer , Sebastian Doberenz , Anne Lorenz , Adrian Kordes , Svenja Grobe , Mathias Müsken , Daniel P Depledge , Sarah L Svensson , Siegfried Weiss , Volkhard Kaever , Andreas Pich , Cynthia M Sharma , Zoya Ignatova , Susanne Häussler

Using Direct RNA Nanopore Sequencing to Deconvolute Viral Transcriptomes.

Current protocols in microbiology

Avec: Daniel P Depledge , Angus C Wilson

Coevolution of Sites under Immune Selection Shapes Epstein-Barr Virus Population Structure.

Molecular biology and evolution

Avec: Fanny Wegner , Florent Lassalle , Daniel P Depledge , François Balloux , Judith Breuer

Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Juliana Cudini , Sunando Roy , Charlotte J Houldcroft , Josephine M Bryant , Daniel P Depledge , Helena Tutill , Paul Veys , Rachel Williams , Austen J J Worth , Asif U Tamuri , Richard A Goldstein , Judith Breuer

Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen.

Nature communications

Avec: Daniel P Depledge , Kalanghad Puthankalam Srinivas , Tomohiko Sadaoka , Devin Bready , Yasuko Mori , Dimitris G Placantonakis , Ian Mohr , Angus C Wilson

The influence of human genetic variation on Epstein-Barr virus sequence diversity.

Scientific reports

Avec: Sina Rüeger , Christian Hammer , Alexis Loetscher , Paul J McLaren , Dylan Lawless , Olivier Naret , Nina Khanna , Enos Bernasconi , Matthias Cavassini , Huldrych F Günthard , Christian R Kahlert , Andri Rauch , Daniel P Depledge , Sofia Morfopoulou , Judith Breuer , Evgeny Zdobnov , Jacques Fellay , Auteur inconnu

Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection.

Viruses

Avec: Shirley E Braspenning , Robert Jan Lebbink , Daniel P Depledge , Claudia M E Schapendonk , Laura A Anderson , Georges M G M Verjans , Tomohiko Sadaoka , Werner J D Ouwendijk

Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome.

Cell host & microbe

Avec: Simone Dallari , Thomas Heaney , Adriana Rosas-Villegas , Jessica A Neil , Serre-Yu Wong , Judy J Brown , Kelly Urbanek , Christin Herrmann , Daniel P Depledge , Terence S Dermody , Ken Cadwell

DRUMMER-rapid detection of RNA modifications through comparative nanopore sequencing.

Bioinformatics (Oxford, England)

Avec: Jonathan S Abebe , Alexander M Price , Katharina E Hayer , Ian Mohr , Matthew D Weitzman , Angus C Wilson , Daniel P Depledge

DLK-Dependent Biphasic Reactivation of Herpes Simplex Virus Latency Established in the Absence of Antivirals.

Journal of virology

Avec: Sara Dochnal , Husain Y Merchant , Austin R Schinlever , Aleksandra Babnis , Daniel P Depledge , Angus C Wilson , Anna R Cliffe

A Variant Allele in Varicella-Zoster Virus Glycoprotein B Selected during Production of the Varicella Vaccine Contributes to Its Attenuation.

mBio

Avec: Tomohiko Sadaoka , Daniel P Depledge , Labchan Rajbhandari , Judith Breuer , Arun Venkatesan , Jeffrey I Cohen

Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice.

bioRxiv : the preprint server for biology

Avec: Werner J D Ouwendijk , Pavitra Roychoudhury , Anthony L Cunningham , Keith R Jerome , David M Koelle , Paul R Kinchington , Ian Mohr , Angus C Wilson , Georges M G M Verjans , Daniel P Depledge

CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.

EMBO reports

Avec: Hannah M Burgess , Rebecca Grande , Sofia Riccio , Ikshitaa Dinesh , Gerlof Sebastiaan Winkler , Daniel P Depledge , Ian Mohr

Histone H2A variant H2A.B is enriched in transcriptionally active and replicating HSV-1 lytic chromatin.

Journal of virology

Avec: Esteban Flores Cortes , Sarah M Saddoris , Arryn K Owens , Rebecca Gibeault , Daniel P Depledge , Luis M Schang

Réseau de co-auteurs

Judith Breuer 14 collaborations

Angus C Wilson 13 collaborations

Ian Mohr 9 collaborations

Jonathan S Abebe 6 collaborations

Werner J D Ouwendijk 6 collaborations

Georges M G M Verjans 5 collaborations

Tomohiko Sadaoka 5 collaborations

Paul R Kinchington 4 collaborations

Luis M Schang 3 collaborations

Alexander M Price 3 collaborations

Katharina E Hayer 3 collaborations

Matthew D Weitzman 3 collaborations

Ruth Verstraten 3 collaborations

Shirley E Braspenning 3 collaborations

Hannah M Burgess 3 collaborations

D Scott Schmid 3 collaborations

Esteban Flores Cortes 2 collaborations

Yasmine Alwie 2 collaborations

Erik Fuhrmann 2 collaborations

Jonas Leins 2 collaborations

Julia Mai 2 collaborations

Sabrina Schreiner 2 collaborations

George Ssebyatika 2 collaborations

Sarah Beyer 2 collaborations

Nina Plückebaum 2 collaborations

Kai A Kropp 2 collaborations

Víctor González-Motos 2 collaborations

Birgit Ritter 2 collaborations

Heike Böning 2 collaborations

Eirini Nikolouli 2 collaborations

Nico Lachmann 2 collaborations

Daniel Pearce Depledge 2 collaborations

Thomas Krey 2 collaborations

Abel Viejo-Borbolla 2 collaborations

Labchan Rajbhandari 2 collaborations

Arun Venkatesan 2 collaborations

Letitia Thompson 2 collaborations

Nancy J Jensen 2 collaborations

Kalanghad Puthankalam Srinivas 2 collaborations

Pavitra Roychoudhury 2 collaborations

Anthony L Cunningham 2 collaborations

Keith R Jerome 2 collaborations

David M Koelle 2 collaborations

Florent Lassalle 2 collaborations

Juliana Cudini 2 collaborations

Sarah M Saddoris 2 collaborations

Arryn K Owens 2 collaborations

Rebecca Gibeault 2 collaborations

MiYao Hu 1 collaboration

Hui-Lan Hu 1 collaboration

Kalanghad P Srinivas 1 collaboration

Shuoshuo Wang 1 collaboration

Moses V Chao 1 collaboration

Timothee Lionnet 1 collaboration

Tony T Huang 1 collaboration

Alexa B R McIntyre 1 collaboration

Nandan S Gokhale 1 collaboration

Ashley N Della Fera 1 collaboration

Christopher E Mason 1 collaboration

Stacy M Horner 1 collaboration

Carina Jürgens 1 collaboration

Juliet Jones 1 collaboration

Katja Ebert-Keel 1 collaboration

Gillian Elliott 1 collaboration

Tihana Lenac Rovis 1 collaboration

Stipan Jonjic 1 collaboration

Robert T Steinbock 1 collaboration

Richard Lauman 1 collaboration

Matthew Charman 1 collaboration

Namrata Kumar 1 collaboration

Edwin Halko 1 collaboration

Krystal K Lum 1 collaboration

Monica Wei 1 collaboration

Benjamin A Garcia 1 collaboration

Carina Jacobsen 1 collaboration

Lucas Mendes-Monteiro 1 collaboration

Jiayi Wang 1 collaboration

Lars Steinbrück 1 collaboration

Claudio Rodríguez-González 1 collaboration

Ruth Harbecke 1 collaboration

Gary R Johnson 1 collaboration

Mark E Ashbaugh 1 collaboration

Myron J Levin 1 collaboration

Michael N Oxman 1 collaboration

Cristina Tommasi 1 collaboration

Clare Rogerson 1 collaboration

Meleri Jones 1 collaboration

Aishath S Naeem 1 collaboration

Cristina Venturini 1 collaboration

Dan Frampton 1 collaboration

Helena J Tutill 1 collaboration

Benjamin Way 1 collaboration

Ryan F L O'Shaughnessy 1 collaboration

Rebecca C Grande 1 collaboration

Elizabeth I Vink 1 collaboration

Wesley P Blackaby 1 collaboration

Alan Hendrick 1 collaboration

Mark R Albertella 1 collaboration

Tony Kouzarides 1 collaboration

Kenneth A Stapleford 1 collaboration

Tamana Mehraban 1 collaboration

Ilhem Messaoudi 1 collaboration

Derek Gatherer 1 collaboration

Carol A Hartley 1 collaboration

Moriah L Szpara 1 collaboration

Paola K Vaz 1 collaboration

Mária Benkő 1 collaboration

Curtis R Brandt 1 collaboration

Neil A Bryant 1 collaboration

Akbar Dastjerdi 1 collaboration

Andor Doszpoly 1 collaboration

Ursula A Gompels 1 collaboration

Naoki Inoue 1 collaboration

Keith W Jarosinski 1 collaboration

Rajeev Kaul 1 collaboration

Vincent Lacoste 1 collaboration

Peter Norberg 1 collaboration

Francesco C Origgi 1 collaboration

Richard J Orton 1 collaboration

Philip E Pellett 1 collaboration

Stephen J Spatz 1 collaboration

James P Stewart 1 collaboration

Jakob Trimpert 1 collaboration

Thomas B Waltzek 1 collaboration

Andrew J Davison 1 collaboration

Maša Mavri 1 collaboration

Valentina Kubale 1 collaboration

Jianmin Zuo 1 collaboration

Christene A Huang 1 collaboration

Milka Vrecl 1 collaboration

Michael A Jarvis 1 collaboration

Eva Jarc Jovičić 1 collaboration

Toni Petan 1 collaboration

Bernhard Ehlers 1 collaboration

Mette M Rosenkilde 1 collaboration

Katja Spiess 1 collaboration

Georges G M G M Verjans 1 collaboration

M J Murray 1 collaboration

N I Bonilla-Medrano 1 collaboration

Q L Lee 1 collaboration

S J Oxenford 1 collaboration

R Angell 1 collaboration

D P Depledge 1 collaboration

M B Reeves 1 collaboration

Terry Fei Fan Ng 1 collaboration

Jessica Leung 1 collaboration

Mark Quinlivan 1 collaboration

Kay W Radford 1 collaboration

Jennifer Folster 1 collaboration

Hung-Fu Tseng 1 collaboration

Philip LaRussa 1 collaboration

Steven J Jacobsen 1 collaboration

Mathew A Beale 1 collaboration

Tehmina Bharucha 1 collaboration

Charlotte A Williams 1 collaboration

Rachel J Williams 1 collaboration

Richard Goldstein 1 collaboration

Tanzina Haque 1 collaboration

Esteban Flores 1 collaboration

Jonas Krueger 1 collaboration

Matthias Preusse 1 collaboration

Nicolas Oswaldo Gomez 1 collaboration

Yannick Noah Frommeyer 1 collaboration

Sebastian Doberenz 1 collaboration

Anne Lorenz 1 collaboration

Adrian Kordes 1 collaboration

Svenja Grobe 1 collaboration

Mathias Müsken 1 collaboration

Sarah L Svensson 1 collaboration

Siegfried Weiss 1 collaboration

Volkhard Kaever 1 collaboration

Andreas Pich 1 collaboration

Cynthia M Sharma 1 collaboration

Zoya Ignatova 1 collaboration

Susanne Häussler 1 collaboration

Fanny Wegner 1 collaboration

François Balloux 1 collaboration

Sunando Roy 1 collaboration

Charlotte J Houldcroft 1 collaboration

Josephine M Bryant 1 collaboration

Helena Tutill 1 collaboration

Paul Veys 1 collaboration

Rachel Williams 1 collaboration

Austen J J Worth 1 collaboration

Asif U Tamuri 1 collaboration

Richard A Goldstein 1 collaboration

Devin Bready 1 collaboration

Yasuko Mori 1 collaboration

Dimitris G Placantonakis 1 collaboration

Sina Rüeger 1 collaboration

Christian Hammer 1 collaboration

Alexis Loetscher 1 collaboration

Paul J McLaren 1 collaboration

Dylan Lawless 1 collaboration

Olivier Naret 1 collaboration

Nina Khanna 1 collaboration

Enos Bernasconi 1 collaboration

Matthias Cavassini 1 collaboration

Huldrych F Günthard 1 collaboration

Christian R Kahlert 1 collaboration

Andri Rauch 1 collaboration

Sofia Morfopoulou 1 collaboration

Evgeny Zdobnov 1 collaboration

Jacques Fellay 1 collaboration

None None 1 collaboration

Robert Jan Lebbink 1 collaboration

Claudia M E Schapendonk 1 collaboration

Laura A Anderson 1 collaboration

Simone Dallari 1 collaboration

Thomas Heaney 1 collaboration

Adriana Rosas-Villegas 1 collaboration

Jessica A Neil 1 collaboration

Serre-Yu Wong 1 collaboration

Judy J Brown 1 collaboration

Kelly Urbanek 1 collaboration

Christin Herrmann 1 collaboration

Terence S Dermody 1 collaboration

Ken Cadwell 1 collaboration

Sara Dochnal 1 collaboration

Husain Y Merchant 1 collaboration

Austin R Schinlever 1 collaboration

Aleksandra Babnis 1 collaboration

Anna R Cliffe 1 collaboration

Jeffrey I Cohen 1 collaboration

Rebecca Grande 1 collaboration

Sofia Riccio 1 collaboration

Ikshitaa Dinesh 1 collaboration

Gerlof Sebastiaan Winkler 1 collaboration