Daniela Iaconis

Affiliations

Dompè Farmaceutici Spa, via Campo di Pile, 1, 67100 L'Aquila, Italy.

ORCID: 0000-0002-1052-6634

Publications (17)

S-Carboxymethyl Cysteine Protects against Oxidative Stress and Mitochondrial Impairment in a Parkinson's Disease In Vitro Model.

Biomedicines

Avec: Mariano Catanesi , Laura Brandolini , Michele d'Angelo , Maria Grazia Tupone , Elisabetta Benedetti , Margherita Alfonsetti , Massimiliano Quintiliani , Maddalena Fratelli , Daniela Iaconis , Annamaria Cimini , Vanessa Castelli , Marcello Allegretti

Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions.

Cell death & disease

Avec: Laura Brandolini , Michele d'Angelo , Rubina Novelli , Vanessa Castelli , Cristina Giorgio , Anna Sirico , Pasquale Cocchiaro , Francesco D'Egidio , Elisabetta Benedetti , Claudia Cristiano , Antonella Bugatti , Anna Ruocco , Pier Giorgio Amendola , Carmine Talarico , Candida Manelfi , Daniela Iaconis , Andrea Beccari , Andreza U Quadros , Thiago M Cunha , Arnaldo Caruso , Roberto Russo , Annamaria Cimini , Andrea Aramini , Marcello Allegretti

The SARS-CoV-2 spike protein binds and modulates estrogen receptors.

bioRxiv : the preprint server for biology

Avec: Oscar Solis , Andrea R Beccari , Daniela Iaconis , Carmine Talarico , Camilo A Ruiz-Bedoya , Jerome C Nwachukwu , Annamaria Cimini , Vanessa Castelli , Riccardo Bertini , Monica Montopoli , Veronica Cocetta , Stefano Borocci , Ingrid G Prandi , Kelly Flavahan , Melissa Bahr , Anna Napiorkowski , Giovanni Chillemi , Masato Ooka , Xiaoping Yang , Shiliang Zhang , Menghang Xia , Wei Zheng , Jordi Bonaventura , Martin G Pomper , Jody E Hooper , Marisela Morales , Avi Z Rosenberg , Kendall W Nettles , Sanjay K Jain , Marcello Allegretti , Michael Michaelides

Regulation of autophagosome biogenesis by OFD1-mediated selective autophagy.

The EMBO journal

Avec: Manuela Morleo , Simona Brillante , Umberto Formisano , Luigi Ferrante , Fabrizia Carbone , Daniela Iaconis , Alessandro Palma , Viviana Buonomo , Angela Serena Maione , Paolo Grumati , Carmine Settembre , Brunella Franco

ProfhEX: AI-based platform for small molecules liability profiling.

Journal of cheminformatics

Avec: Filippo Lunghini , Anna Fava , Vincenzo Pisapia , Francesco Sacco , Daniela Iaconis , Andrea Rosario Beccari

Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen.

ACS pharmacology & translational science

Avec: Maria Kuzikov , Elisa Costanzi , Jeanette Reinshagen , Francesca Esposito , Laura Vangeel , Markus Wolf , Bernhard Ellinger , Carsten Claussen , Gerd Geisslinger , Angela Corona , Daniela Iaconis , Carmine Talarico , Candida Manelfi , Rolando Cannalire , Giulia Rossetti , Jonas Gossen , Simone Albani , Francesco Musiani , Katja Herzog , Yang Ye , Barbara Giabbai , Nicola Demitri , Dirk Jochmans , Steven De Jonghe , Jasper Rymenants , Vincenzo Summa , Enzo Tramontano , Andrea R Beccari , Pieter Leyssen , Paola Storici , Johan Neyts , Philip Gribbon , Andrea Zaliani

Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities.

ACS pharmacology & translational science

Avec: Angela Corona , Krzysztof Wycisk , Carmine Talarico , Candida Manelfi , Jessica Milia , Rolando Cannalire , Francesca Esposito , Philip Gribbon , Andrea Zaliani , Daniela Iaconis , Andrea R Beccari , Vincenzo Summa , Marcin Nowotny , Enzo Tramontano

Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort.

Scientific data

Avec: Andrea Zaliani , Laura Vangeel , Jeanette Reinshagen , Daniela Iaconis , Maria Kuzikov , Oliver Keminer , Markus Wolf , Bernhard Ellinger , Francesca Esposito , Angela Corona , Enzo Tramontano , Candida Manelfi , Katja Herzog , Dirk Jochmans , Steven De Jonghe , Winston Chiu , Thibault Francken , Joost Schepers , Caroline Collard , Kayvan Abbasi , Carsten Claussen , Vincenzo Summa , Andrea R Beccari , Johan Neyts , Philip Gribbon , Pieter Leyssen

Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex.

Virus research

Avec: Maria Kuzikov , Jeanette Reinshagen , Krzysztof Wycisk , Angela Corona , Francesca Esposito , Paolo Malune , Candida Manelfi , Daniela Iaconis , Andrea Beccari , Enzo Tramontano , Marcin Nowotny , Björn Windshügel , Philip Gribbon , Andrea Zaliani

The centrosomal/basal body protein OFD1 is required for microtubule organization and cell cycle progression.

Tissue & cell

Avec: Mariaevelina Alfieri , Daniela Iaconis , Roberta Tammaro , Lucia Perone , Gaetano Calì , Lucio Nitsch , Gerard W Dougherty , Antonella Ragnini-Wilson , Brunella Franco

The HOPS complex subunit VPS39 controls ciliogenesis through autophagy.

Human molecular genetics

Avec: Daniela Iaconis , Claudia Crina , Simona Brillante , Alessia Indrieri , Manuela Morleo , Brunella Franco

Characterization of raloxifene as a potential pharmacological agent against SARS-CoV-2 and its variants.

Cell death & disease

Avec: Daniela Iaconis , Licia Bordi , Giulia Matusali , Carmine Talarico , Candida Manelfi , Maria Candida Cesta , Mara Zippoli , Francesca Caccuri , Antonella Bugatti , Alberto Zani , Federica Filippini , Laura Scorzolini , Marco Gobbi , Marten Beeg , Arianna Piotti , Monica Montopoli , Veronica Cocetta , Silvia Bressan , Enrico M Bucci , Arnaldo Caruso , Emanuele Nicastri , Marcello Allegretti , Andrea R Beccari

Development of a novel SNP assay to detect lactase persistence associated genetic variants.

Molecular biology reports

Avec: Pasquale De Luca , Daniela Iaconis , Elio Biffali , Coluccia Enza , Laura de Magistris , Gabriele Riegler , Diego Pappalardo , Maria Rosaria Amato , Patrizia Iardino , Concetta Montanino , Bruna De Felice

L-Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson's Disease.

Antioxidants (Basel, Switzerland)

Avec: Mariano Catanesi , Laura Brandolini , Michele d'Angelo , Elisabetta Benedetti , Maria Grazia Tupone , Margherita Alfonsetti , Enrico Cabri , Daniela Iaconis , Maddalena Fratelli , Annamaria Cimini , Vanessa Castelli , Marcello Allegretti

Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication.

Antiviral research

Avec: Angela Corona , Valentina Noemi Madia , Riccardo De Santis , Candida Manelfi , Roberta Emmolo , Davide Ialongo , Elisa Patacchini , Antonella Messore , Donatella Amatore , Giovanni Faggioni , Marco Artico , Daniela Iaconis , Carmine Talarico , Roberto Di Santo , Florigio Lista , Roberta Costi , Enzo Tramontano

DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action.

Viruses

Avec: Daniela Iaconis , Francesca Caccuri , Candida Manelfi , Carmine Talarico , Antonella Bugatti , Federica Filippini , Alberto Zani , Rubina Novelli , Maria Kuzikov , Bernhard Ellinger , Philip Gribbon , Kristoffer Riecken , Francesca Esposito , Angela Corona , Enzo Tramontano , Andrea Rosario Beccari , Arnaldo Caruso , Marcello Allegretti

The SARS-CoV-2 spike protein binds and modulates estrogen receptors.

Science advances

Avec: Oscar Solis , Andrea R Beccari , Daniela Iaconis , Carmine Talarico , Camilo A Ruiz-Bedoya , Jerome C Nwachukwu , Annamaria Cimini , Vanessa Castelli , Riccardo Bertini , Monica Montopoli , Veronica Cocetta , Stefano Borocci , Ingrid G Prandi , Kelly Flavahan , Melissa Bahr , Anna Napiorkowski , Giovanni Chillemi , Masato Ooka , Xiaoping Yang , Shiliang Zhang , Menghang Xia , Wei Zheng , Jordi Bonaventura , Martin G Pomper , Jody E Hooper , Marisela Morales , Avi Z Rosenberg , Kendall W Nettles , Sanjay K Jain , Marcello Allegretti , Michael Michaelides

Réseau de co-auteurs

Carmine Talarico 8 collaborations

Candida Manelfi 8 collaborations

Marcello Allegretti 7 collaborations

Andrea R Beccari 6 collaborations

Angela Corona 6 collaborations

Enzo Tramontano 6 collaborations

Annamaria Cimini 5 collaborations

Vanessa Castelli 5 collaborations

Francesca Esposito 5 collaborations

Philip Gribbon 5 collaborations

Maria Kuzikov 4 collaborations

Andrea Zaliani 4 collaborations

Laura Brandolini 3 collaborations

Michele d'Angelo 3 collaborations

Elisabetta Benedetti 3 collaborations

Antonella Bugatti 3 collaborations

Arnaldo Caruso 3 collaborations

Monica Montopoli 3 collaborations

Veronica Cocetta 3 collaborations

Brunella Franco 3 collaborations

Jeanette Reinshagen 3 collaborations

Bernhard Ellinger 3 collaborations

Vincenzo Summa 3 collaborations

Mariano Catanesi 2 collaborations

Maria Grazia Tupone 2 collaborations

Margherita Alfonsetti 2 collaborations

Maddalena Fratelli 2 collaborations

Rubina Novelli 2 collaborations

Andrea Beccari 2 collaborations

Oscar Solis 2 collaborations

Camilo A Ruiz-Bedoya 2 collaborations

Jerome C Nwachukwu 2 collaborations

Riccardo Bertini 2 collaborations

Stefano Borocci 2 collaborations

Ingrid G Prandi 2 collaborations

Kelly Flavahan 2 collaborations

Melissa Bahr 2 collaborations

Anna Napiorkowski 2 collaborations

Giovanni Chillemi 2 collaborations

Masato Ooka 2 collaborations

Xiaoping Yang 2 collaborations

Shiliang Zhang 2 collaborations

Menghang Xia 2 collaborations

Wei Zheng 2 collaborations

Jordi Bonaventura 2 collaborations

Martin G Pomper 2 collaborations

Jody E Hooper 2 collaborations

Marisela Morales 2 collaborations

Avi Z Rosenberg 2 collaborations

Kendall W Nettles 2 collaborations

Sanjay K Jain 2 collaborations

Michael Michaelides 2 collaborations

Manuela Morleo 2 collaborations

Simona Brillante 2 collaborations

Andrea Rosario Beccari 2 collaborations

Laura Vangeel 2 collaborations

Markus Wolf 2 collaborations

Carsten Claussen 2 collaborations

Rolando Cannalire 2 collaborations

Katja Herzog 2 collaborations

Dirk Jochmans 2 collaborations

Steven De Jonghe 2 collaborations

Pieter Leyssen 2 collaborations

Johan Neyts 2 collaborations

Krzysztof Wycisk 2 collaborations

Marcin Nowotny 2 collaborations

Francesca Caccuri 2 collaborations

Alberto Zani 2 collaborations

Federica Filippini 2 collaborations

Massimiliano Quintiliani 1 collaboration

Cristina Giorgio 1 collaboration

Anna Sirico 1 collaboration

Pasquale Cocchiaro 1 collaboration

Francesco D'Egidio 1 collaboration

Claudia Cristiano 1 collaboration

Anna Ruocco 1 collaboration

Pier Giorgio Amendola 1 collaboration

Andreza U Quadros 1 collaboration

Thiago M Cunha 1 collaboration

Roberto Russo 1 collaboration

Andrea Aramini 1 collaboration

Umberto Formisano 1 collaboration

Luigi Ferrante 1 collaboration

Fabrizia Carbone 1 collaboration

Alessandro Palma 1 collaboration

Viviana Buonomo 1 collaboration

Angela Serena Maione 1 collaboration

Paolo Grumati 1 collaboration

Carmine Settembre 1 collaboration

Filippo Lunghini 1 collaboration

Anna Fava 1 collaboration

Vincenzo Pisapia 1 collaboration

Francesco Sacco 1 collaboration

Elisa Costanzi 1 collaboration

Gerd Geisslinger 1 collaboration

Giulia Rossetti 1 collaboration

Jonas Gossen 1 collaboration

Simone Albani 1 collaboration

Francesco Musiani 1 collaboration

Yang Ye 1 collaboration

Barbara Giabbai 1 collaboration

Nicola Demitri 1 collaboration

Jasper Rymenants 1 collaboration

Paola Storici 1 collaboration

Jessica Milia 1 collaboration

Oliver Keminer 1 collaboration

Winston Chiu 1 collaboration

Thibault Francken 1 collaboration

Joost Schepers 1 collaboration

Caroline Collard 1 collaboration

Kayvan Abbasi 1 collaboration

Paolo Malune 1 collaboration

Björn Windshügel 1 collaboration

Mariaevelina Alfieri 1 collaboration

Roberta Tammaro 1 collaboration

Lucia Perone 1 collaboration

Gaetano Calì 1 collaboration

Lucio Nitsch 1 collaboration

Gerard W Dougherty 1 collaboration

Antonella Ragnini-Wilson 1 collaboration

Claudia Crina 1 collaboration

Alessia Indrieri 1 collaboration

Licia Bordi 1 collaboration

Giulia Matusali 1 collaboration

Maria Candida Cesta 1 collaboration

Mara Zippoli 1 collaboration

Laura Scorzolini 1 collaboration

Marco Gobbi 1 collaboration

Marten Beeg 1 collaboration

Arianna Piotti 1 collaboration

Silvia Bressan 1 collaboration

Enrico M Bucci 1 collaboration

Emanuele Nicastri 1 collaboration

Pasquale De Luca 1 collaboration

Elio Biffali 1 collaboration

Coluccia Enza 1 collaboration

Laura de Magistris 1 collaboration

Gabriele Riegler 1 collaboration

Diego Pappalardo 1 collaboration

Maria Rosaria Amato 1 collaboration

Patrizia Iardino 1 collaboration

Concetta Montanino 1 collaboration

Bruna De Felice 1 collaboration

Enrico Cabri 1 collaboration

Valentina Noemi Madia 1 collaboration

Riccardo De Santis 1 collaboration

Roberta Emmolo 1 collaboration

Davide Ialongo 1 collaboration

Elisa Patacchini 1 collaboration

Antonella Messore 1 collaboration

Donatella Amatore 1 collaboration

Giovanni Faggioni 1 collaboration

Marco Artico 1 collaboration

Roberto Di Santo 1 collaboration

Florigio Lista 1 collaboration

Roberta Costi 1 collaboration

Kristoffer Riecken 1 collaboration