David C Wraith

Affiliations

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K.

Publications (26)

Serology confirms SARS-CoV-2 infection in PCR-negative children presenting with Paediatric Inflammatory Multi-System Syndrome.

medRxiv : the preprint server for health sciences

Avec: Marisol Perez-Toledo , Sian E Faustini , Sian E Jossi , Adrian M Shields , Hari Krishnan Kanthimathinathan , Joel D Allen , Yasunori Watanabe , Margaret Goodall , David C Wraith , Tonny V Veenith , Mark T Drayson , Deepthi Jyothish , Eslam Al-Abadi , Ashish Chikermane , Steven B Welch , Kavitha Masilamani , Scott Hackett , Max Crispin , Barnaby R Scholefield , Adam F Cunningham , Alex G Richter

Adaptive T cell tuning in immune regulation and immunotherapy of autoimmune diseases

Immunology letters

Avec: David C Wraith

Development of a high-sensitivity ELISA detecting IgG, IgA and IgM antibodies to the SARS-CoV-2 spike glycoprotein in serum and saliva.

Immunology

Avec: Sian E Faustini , Sian E Jossi , Marisol Perez-Toledo , Adrian M Shields , Joel D Allen , Yasunori Watanabe , Maddy L Newby , Alex Cook , Carrie R Willcox , Mahboob Salim , Margaret Goodall , Jennifer L Heaney , Edith Marcial-Juarez , Gabriella L Morley , Barbara Torlinska , David C Wraith , Tonny V Veenith , Stephen Harding , Stephen Jolles , Mark J Ponsford , Tim Plant , Aarnoud Huissoon , Matthew K O'Shea , Benjamin E Willcox , Mark T Drayson , Max Crispin , Adam F Cunningham , Alex G Richter

Therapies for Long COVID in non-hospitalised individuals: from symptoms, patient-reported outcomes and immunology to targeted therapies (The TLC Study).

BMJ open

Avec: Shamil Haroon , Krishnarajah Nirantharakumar , Sarah E Hughes , Anuradhaa Subramanian , Olalekan Lee Aiyegbusi , Elin Haf Davies , Puja Myles , Tim Williams , Grace Turner , Joht Singh Chandan , Christel McMullan , Janet Lord , David C Wraith , Kirsty McGee , Alastair K Denniston , Thomas Taverner , Louise J Jackson , Elizabeth Sapey , George Gkoutos , Krishna Gokhale , Edward Leggett , Clare Iles , Christopher Frost , Gary McNamara , Amy Bamford , Tom Marshall , Dawit T Zemedikun , Gary Price , Steven Marwaha , Nikita Simms-Williams , Kirsty Brown , Anita Walker , Karen Jones , Karen Matthews , Jennifer Camaradou , Michael Saint-Cricq , Sumita Kumar , Yvonne Alder , David E Stanton , Lisa Agyen , Megan Baber , Hannah Blaize , Melanie Calvert

SARS-CoV-2 Spike- and Nucleoprotein-Specific Antibodies Induced After Vaccination or Infection Promote Classical Complement Activation.

Frontiers in immunology

Avec: Rachel E Lamerton , Edith Marcial-Juarez , Sian E Faustini , Marisol Perez-Toledo , Margaret Goodall , Siân E Jossi , Maddy L Newby , Iain Chapple , Thomas Dietrich , Tonny Veenith , Adrian M Shields , Lorraine Harper , Ian R Henderson , Julie Rayes , David C Wraith , Steve P Watson , Max Crispin , Mark T Drayson , Alex G Richter , Adam F Cunningham

Serological responses to SARS-CoV-2 following non-hospitalised infection: clinical and ethnodemographic features associated with the magnitude of the antibody response.

BMJ open respiratory research

Avec: Adrian M Shields , Sian E Faustini , Marisol Perez-Toledo , Sian Jossi , Joel D Allen , Saly Al-Taei , Claire Backhouse , Lynsey A Dunbar , Daniel Ebanks , Beena Emmanuel , Aduragbemi A Faniyi , Mark Garvey , Annabel Grinbergs , Golaleh McGinnell , Joanne O'Neill , Yasunori Watanabe , Max Crispin , David C Wraith , Adam F Cunningham , Mark T Drayson , Alex G Richter

Manipulating antigen presentation for antigen-specific immunotherapy of autoimmune diseases.

Current opinion in immunology

Avec: Heather B Streeter , David C Wraith

Peptide allergen-specific immunotherapy for allergic airway diseases-State of the art.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Avec: David C Wraith , Mamidipudi T Krishna

SARS-CoV-2 infection is associated with anti-desmoglein 2 autoantibody detection.

Clinical and experimental immunology

Avec: Kerensa E Ward , Lora Steadman , Abid R Karim , Gary M Reynolds , Matthew Pugh , Winnie Chua , Sian E Faustini , Tonny Veenith , Ryan S Thwaites , Peter J M Openshaw , Mark T Drayson , Adrian M Shields , Adam F Cunningham , David C Wraith , Alex G Richter

Antigen-specific immunotherapy with apitopes suppresses generation of FVIII inhibitor antibodies in HLA-transgenic mice.

Blood advances

Avec: Katrien Pletinckx , Kirsty S Nicolson , Heather B Streeter , William J Sanderson , Evelien Schurgers , Lotta Jansson , David C Wraith

Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength.

Immunity

Avec: Thomas A E Elliot , Emma K Jennings , David A J Lecky , Natasha Thawait , Adriana Flores-Langarica , Alastair Copland , Kendle M Maslowski , David C Wraith , David Bending

Induction of Tolerance to Therapeutic Proteins With Antigen-Processing Independent T Cell Epitopes: Controlling Immune Responses to Biologics.

Frontiers in immunology

Avec: Evelien Schurgers , David C Wraith

A LAT-Based Signaling Complex in the Immunological Synapse as Determined with Live Cell Imaging Is Less Stable in T Cells with Regulatory Capability.

Cells

Avec: Yikui Li , Helen M Tunbridge , Graham J Britton , Elaine V Hill , Parisa Sinai , Silvia Cirillo , Clare Thompson , Farnaz Fallah-Arani , Simon J Dovedi , David C Wraith , Christoph Wülfing

Serological responses to SARS-CoV-2 following non-hospitalised infection: clinical and ethnodemographic features associated with the magnitude of the antibody response.

medRxiv : the preprint server for health sciences

Avec: Adrian M Shields , Sian E Faustini , Marisol Perez-Toledo , Sian Jossi , Joel D Allen , Saly Al-Taei , Claire Backhouse , Lynsey Dunbar , Daniel Ebanks , Beena Emmanuel , Aduragbemi A Faniyi , Mark I Garvey , Annabel Grinbergs , Golaleh McGinnell , Joanne O'Neill , Yasunori Watanabe , Max Crispin , David C Wraith , Adam F Cunningham , Mark T Drayson , Alex G Richter

Establishing the prevalence of common tissue-specific autoantibodies following severe acute respiratory syndrome coronavirus 2 infection.

Clinical and experimental immunology

Avec: Alex G Richter , Adrian M Shields , Abid Karim , David Birch , Sian E Faustini , Lora Steadman , Kerensa Ward , Timothy Plant , Gary Reynolds , Tonny Veenith , Adam F Cunningham , Mark T Drayson , David C Wraith

Preclinical models of arthritis for studying immunotherapy and immune tolerance.

Annals of the rheumatic diseases

Avec: Gavin R Meehan , Ranjeny Thomas , Shaima Al Khabouri , Pascale Wehr , Catharien Mu Hilkens , David C Wraith , Daniela Sieghart , Michael Bonelli , György Nagy , Paul Garside , David F Tough , Huw D Lewis , James M Brewer

Autoantigens in rheumatoid arthritis and the potential for antigen-specific tolerising immunotherapy.

The Lancet. Rheumatology

Avec: Hendrik J Nel , Vivianne Malmström , David C Wraith , Ranjeny Thomas

Incidence of immune-mediated inflammatory diseases following COVID-19: a matched cohort study in UK primary care.

BMC medicine

Avec: Umer Syed , Anuradhaa Subramanian , David C Wraith , Janet M Lord , Kirsty McGee , Krishna Ghokale , Krishnarajah Nirantharakumar , Shamil Haroon

Detection of antibodies to the SARS-CoV-2 spike glycoprotein in both serum and saliva enhances detection of infection.

medRxiv : the preprint server for health sciences

Antigen-Specific Immunotherapy for Treatment of Autoimmune Liver Diseases.

Frontiers in immunology

Avec: Naomi Richardson , Sky T H Ng , David C Wraith

Chromatin Priming Renders T Cell Tolerance-Associated Genes Sensitive to Activation below the Signaling Threshold for Immune Response Genes.

Cell reports

Avec: Sarah L Bevington , Sky T H Ng , Graham J Britton , Peter Keane , David C Wraith , Peter N Cockerill

Nr4a1 and Nr4a3 Reporter Mice Are Differentially Sensitive to T Cell Receptor Signal Strength and Duration.

Cell reports

Avec: Emma Jennings , Thomas A E Elliot , Natasha Thawait , Shivani Kanabar , Juan Carlos Yam-Puc , Masahiro Ono , Kai-Michael Toellner , David C Wraith , Graham Anderson , David Bending

The Mechanism of Action of Antigen Processing Independent T Cell Epitopes Designed for Immunotherapy of Autoimmune Diseases.

Frontiers in immunology

Avec: Ella R Shepard , Anja Wegner , Elaine V Hill , Bronwen R Burton , Sarah Aerts , Evelien Schurgers , Brecht Hoedemaekers , Sky T H Ng , Heather B Streeter , Lotta Jansson , David C Wraith

SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study.

Thorax

Avec: Adrian Shields , Sian E Faustini , Marisol Perez-Toledo , Sian Jossi , Erin Aldera , Joel D Allen , Saly Al-Taei , Claire Backhouse , Andrew Bosworth , Lyndsey A Dunbar , Daniel Ebanks , Beena Emmanuel , Mark Garvey , Joanna Gray , I Michael Kidd , Golaleh McGinnell , Dee E McLoughlin , Gabriella Morley , Joanna O'Neill , Danai Papakonstantinou , Oliver Pickles , Charlotte Poxon , Megan Richter , Eloise M Walker , Kasun Wanigasooriya , Yasunori Watanabe , Celina Whalley , Agnieszka E Zielinska , Max Crispin , David C Wraith , Andrew D Beggs , Adam F Cunningham , Mark T Drayson , Alex G Richter

Symptoms and risk factors for long COVID in non-hospitalized adults.

Nature medicine

Avec: Anuradhaa Subramanian , Krishnarajah Nirantharakumar , Sarah Hughes , Puja Myles , Tim Williams , Krishna M Gokhale , Tom Taverner , Joht Singh Chandan , Kirsty Brown , Nikita Simms-Williams , Anoop D Shah , Megha Singh , Farah Kidy , Kelvin Okoth , Richard Hotham , Nasir Bashir , Neil Cockburn , Siang Ing Lee , Grace M Turner , Georgios V Gkoutos , Olalekan Lee Aiyegbusi , Christel McMullan , Alastair K Denniston , Elizabeth Sapey , Janet M Lord , David C Wraith , Edward Leggett , Clare Iles , Tom Marshall , Malcolm J Price , Steven Marwaha , Elin Haf Davies , Louise J Jackson , Karen L Matthews , Jenny Camaradou , Melanie Calvert , Shamil Haroon

Advancement of antigen-specific immunotherapy: knowledge transfer between allergy and autoimmunity.

Immunotherapy advances

Avec: Naomi Richardson , David Cameron Wraith

Réseau de co-auteurs

Sian E Faustini 9 collaborations

Mark T Drayson 9 collaborations

Adam F Cunningham 9 collaborations

Alex G Richter 9 collaborations

Adrian M Shields 8 collaborations

Marisol Perez-Toledo 7 collaborations

Max Crispin 7 collaborations

Joel D Allen 6 collaborations

Yasunori Watanabe 6 collaborations

Margaret Goodall 4 collaborations

Sian E Jossi 3 collaborations

Tonny V Veenith 3 collaborations

Maddy L Newby 3 collaborations

Edith Marcial-Juarez 3 collaborations

Shamil Haroon 3 collaborations

Krishnarajah Nirantharakumar 3 collaborations

Anuradhaa Subramanian 3 collaborations

Tonny Veenith 3 collaborations

Sian Jossi 3 collaborations

Saly Al-Taei 3 collaborations

Claire Backhouse 3 collaborations

Daniel Ebanks 3 collaborations

Beena Emmanuel 3 collaborations

Golaleh McGinnell 3 collaborations

Heather B Streeter 3 collaborations

Evelien Schurgers 3 collaborations

Sky T H Ng 3 collaborations

Alex Cook 2 collaborations

Carrie R Willcox 2 collaborations

Mahboob Salim 2 collaborations

Jennifer L Heaney 2 collaborations

Gabriella L Morley 2 collaborations

Barbara Torlinska 2 collaborations

Stephen Harding 2 collaborations

Stephen Jolles 2 collaborations

Mark J Ponsford 2 collaborations

Tim Plant 2 collaborations

Aarnoud Huissoon 2 collaborations

Matthew K O'Shea 2 collaborations

Benjamin E Willcox 2 collaborations

Olalekan Lee Aiyegbusi 2 collaborations

Elin Haf Davies 2 collaborations

Puja Myles 2 collaborations

Tim Williams 2 collaborations

Joht Singh Chandan 2 collaborations

Christel McMullan 2 collaborations

Kirsty McGee 2 collaborations

Alastair K Denniston 2 collaborations

Louise J Jackson 2 collaborations

Elizabeth Sapey 2 collaborations

Edward Leggett 2 collaborations

Clare Iles 2 collaborations

Tom Marshall 2 collaborations

Steven Marwaha 2 collaborations

Nikita Simms-Williams 2 collaborations

Kirsty Brown 2 collaborations

Melanie Calvert 2 collaborations

Aduragbemi A Faniyi 2 collaborations

Mark Garvey 2 collaborations

Annabel Grinbergs 2 collaborations

Joanne O'Neill 2 collaborations

Lora Steadman 2 collaborations

Lotta Jansson 2 collaborations

Thomas A E Elliot 2 collaborations

Natasha Thawait 2 collaborations

David Bending 2 collaborations

Graham J Britton 2 collaborations

Elaine V Hill 2 collaborations

Ranjeny Thomas 2 collaborations

Janet M Lord 2 collaborations

Naomi Richardson 2 collaborations

Hari Krishnan Kanthimathinathan 1 collaboration

Deepthi Jyothish 1 collaboration

Eslam Al-Abadi 1 collaboration

Ashish Chikermane 1 collaboration

Steven B Welch 1 collaboration

Kavitha Masilamani 1 collaboration

Scott Hackett 1 collaboration

Barnaby R Scholefield 1 collaboration

Sarah E Hughes 1 collaboration

Grace Turner 1 collaboration

Janet Lord 1 collaboration

Thomas Taverner 1 collaboration

George Gkoutos 1 collaboration

Krishna Gokhale 1 collaboration

Christopher Frost 1 collaboration

Gary McNamara 1 collaboration

Amy Bamford 1 collaboration

Dawit T Zemedikun 1 collaboration

Gary Price 1 collaboration

Anita Walker 1 collaboration

Karen Jones 1 collaboration

Karen Matthews 1 collaboration

Jennifer Camaradou 1 collaboration

Michael Saint-Cricq 1 collaboration

Sumita Kumar 1 collaboration

Yvonne Alder 1 collaboration

David E Stanton 1 collaboration

Lisa Agyen 1 collaboration

Megan Baber 1 collaboration

Hannah Blaize 1 collaboration

Rachel E Lamerton 1 collaboration

Siân E Jossi 1 collaboration

Iain Chapple 1 collaboration

Thomas Dietrich 1 collaboration

Lorraine Harper 1 collaboration

Ian R Henderson 1 collaboration

Julie Rayes 1 collaboration

Steve P Watson 1 collaboration

Lynsey A Dunbar 1 collaboration

Mamidipudi T Krishna 1 collaboration

Kerensa E Ward 1 collaboration

Abid R Karim 1 collaboration

Gary M Reynolds 1 collaboration

Matthew Pugh 1 collaboration

Winnie Chua 1 collaboration

Ryan S Thwaites 1 collaboration

Peter J M Openshaw 1 collaboration

Katrien Pletinckx 1 collaboration

Kirsty S Nicolson 1 collaboration

William J Sanderson 1 collaboration

Emma K Jennings 1 collaboration

David A J Lecky 1 collaboration

Adriana Flores-Langarica 1 collaboration

Alastair Copland 1 collaboration

Kendle M Maslowski 1 collaboration

Yikui Li 1 collaboration

Helen M Tunbridge 1 collaboration

Parisa Sinai 1 collaboration

Silvia Cirillo 1 collaboration

Clare Thompson 1 collaboration

Farnaz Fallah-Arani 1 collaboration

Simon J Dovedi 1 collaboration

Christoph Wülfing 1 collaboration

Lynsey Dunbar 1 collaboration

Mark I Garvey 1 collaboration

Abid Karim 1 collaboration

David Birch 1 collaboration

Kerensa Ward 1 collaboration

Timothy Plant 1 collaboration

Gary Reynolds 1 collaboration

Gavin R Meehan 1 collaboration

Shaima Al Khabouri 1 collaboration

Pascale Wehr 1 collaboration

Catharien Mu Hilkens 1 collaboration

Daniela Sieghart 1 collaboration

Michael Bonelli 1 collaboration

György Nagy 1 collaboration

Paul Garside 1 collaboration

David F Tough 1 collaboration

Huw D Lewis 1 collaboration

James M Brewer 1 collaboration

Hendrik J Nel 1 collaboration

Vivianne Malmström 1 collaboration

Umer Syed 1 collaboration

Krishna Ghokale 1 collaboration

Sarah L Bevington 1 collaboration

Peter Keane 1 collaboration

Peter N Cockerill 1 collaboration

Emma Jennings 1 collaboration

Shivani Kanabar 1 collaboration

Juan Carlos Yam-Puc 1 collaboration

Masahiro Ono 1 collaboration

Kai-Michael Toellner 1 collaboration

Graham Anderson 1 collaboration

Ella R Shepard 1 collaboration

Anja Wegner 1 collaboration

Bronwen R Burton 1 collaboration

Sarah Aerts 1 collaboration

Brecht Hoedemaekers 1 collaboration

Adrian Shields 1 collaboration

Erin Aldera 1 collaboration

Andrew Bosworth 1 collaboration

Lyndsey A Dunbar 1 collaboration

Joanna Gray 1 collaboration

I Michael Kidd 1 collaboration

Dee E McLoughlin 1 collaboration

Gabriella Morley 1 collaboration

Joanna O'Neill 1 collaboration

Danai Papakonstantinou 1 collaboration

Oliver Pickles 1 collaboration

Charlotte Poxon 1 collaboration

Megan Richter 1 collaboration

Eloise M Walker 1 collaboration

Kasun Wanigasooriya 1 collaboration

Celina Whalley 1 collaboration

Agnieszka E Zielinska 1 collaboration

Andrew D Beggs 1 collaboration

Sarah Hughes 1 collaboration

Krishna M Gokhale 1 collaboration

Tom Taverner 1 collaboration

Anoop D Shah 1 collaboration

Megha Singh 1 collaboration

Farah Kidy 1 collaboration

Kelvin Okoth 1 collaboration

Richard Hotham 1 collaboration

Nasir Bashir 1 collaboration

Neil Cockburn 1 collaboration

Siang Ing Lee 1 collaboration

Grace M Turner 1 collaboration

Georgios V Gkoutos 1 collaboration

Malcolm J Price 1 collaboration

Karen L Matthews 1 collaboration

Jenny Camaradou 1 collaboration

David Cameron Wraith 1 collaboration