David Carling

Affiliations

Medical Research Council London Institute of Medical Sciences, Imperial College London, Hammersmith Hospital, London, UK.

Publications (7)

A loss-of-function NUAK2 mutation in humans causes anencephaly due to impaired Hippo-YAP signaling.

The Journal of experimental medicine

Avec: Carine Bonnard , Naveenan Navaratnam , Kakaly Ghosh , Puck Wee Chan , Thong Teck Tan , Oz Pomp , Alvin Yu Jin Ng , Sumanty Tohari , Rishita Changede , David Carling , Byrappa Venkatesh , Umut Altunoglu , Hülya Kayserili , Bruno Reversade

Chronic activation of AMP-activated protein kinase leads to early-onset polycystic kidney phenotype.

Clinical science (London, England : 1979)

Avec: Laura Wilson , Alice E Pollard , Lucy Penfold , Phillip J Muckett , Chad Whilding , Mohammad Bohlooly-Y , Patricia Wilson , David Carling

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495.

The Biochemical journal

Avec: Katrin Spengler , Darya Zibrova , Angela Woods , Christopher G Langendorf , John W Scott , David Carling , Regine Heller

Thermogenic adipocytes: lineage, function and therapeutic potential.

The Biochemical journal

Avec: Alice E Pollard , David Carling

The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer.

British journal of cancer

Avec: Theodora A Constantin , Anabel Varela-Carver , Kyle K Greenland , Gilberto Serrano de Almeida , Ellen Olden , Lucy Penfold , Simon Ang , Alice Ormrod , Damien A Leach , Chun-Fui Lai , Edward K Ainscow , Ash K Bahl , David Carling , Matthew J Fuchter , Simak Ali , Charlotte L Bevan

AMPK activation protects against prostate cancer by inducing a catabolic cellular state.

Cell reports

Avec: Lucy Penfold , Angela Woods , Alice E Pollard , Julia Arizanova , Eneko Pascual-Navarro , Phillip J Muckett , Marian H Dore , Alex Montoya , Chad Whilding , Louise Fets , Joao Mokochinski , Theodora A Constantin , Anabel Varela-Carver , Damien A Leach , Charlotte L Bevan , Alexander Yu Nikitin , Zoe Hall , David Carling

Hematoma Resolution In Vivo Is Directed by Activating Transcription Factor 1.

Circulation research

Avec: Anusha Seneviratne , Yumeng Han , Eunice Wong , Edward R H Walter , Lijun Jiang , Luke Cave , Nicholas J Long , David Carling , Justin C Mason , Dorian O Haskard , Joseph J Boyle

Réseau de co-auteurs

Alice E Pollard 3 collaborations

Lucy Penfold 3 collaborations

Phillip J Muckett 2 collaborations

Chad Whilding 2 collaborations

Angela Woods 2 collaborations

Theodora A Constantin 2 collaborations

Anabel Varela-Carver 2 collaborations

Damien A Leach 2 collaborations

Charlotte L Bevan 2 collaborations

Carine Bonnard 1 collaboration

Naveenan Navaratnam 1 collaboration

Kakaly Ghosh 1 collaboration

Puck Wee Chan 1 collaboration

Thong Teck Tan 1 collaboration

Oz Pomp 1 collaboration

Alvin Yu Jin Ng 1 collaboration

Sumanty Tohari 1 collaboration

Rishita Changede 1 collaboration

Byrappa Venkatesh 1 collaboration

Umut Altunoglu 1 collaboration

Hülya Kayserili 1 collaboration

Bruno Reversade 1 collaboration

Laura Wilson 1 collaboration

Mohammad Bohlooly-Y 1 collaboration

Patricia Wilson 1 collaboration

Katrin Spengler 1 collaboration

Darya Zibrova 1 collaboration

Christopher G Langendorf 1 collaboration

John W Scott 1 collaboration

Regine Heller 1 collaboration

Kyle K Greenland 1 collaboration

Gilberto Serrano de Almeida 1 collaboration

Ellen Olden 1 collaboration

Simon Ang 1 collaboration

Alice Ormrod 1 collaboration

Chun-Fui Lai 1 collaboration

Edward K Ainscow 1 collaboration

Ash K Bahl 1 collaboration

Matthew J Fuchter 1 collaboration

Simak Ali 1 collaboration

Julia Arizanova 1 collaboration

Eneko Pascual-Navarro 1 collaboration

Marian H Dore 1 collaboration

Alex Montoya 1 collaboration

Louise Fets 1 collaboration

Joao Mokochinski 1 collaboration

Alexander Yu Nikitin 1 collaboration

Zoe Hall 1 collaboration

Anusha Seneviratne 1 collaboration

Yumeng Han 1 collaboration

Eunice Wong 1 collaboration

Edward R H Walter 1 collaboration

Lijun Jiang 1 collaboration

Luke Cave 1 collaboration

Nicholas J Long 1 collaboration

Justin C Mason 1 collaboration

Dorian O Haskard 1 collaboration

Joseph J Boyle 1 collaboration