David E MacHugh

Affiliations

Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

Publications (35)

Frontiers in immunology

Avec: Andres Garcia-Campos , Carolina N Correia , Amalia Naranjo-Lucena , Laura Garza-Cuartero , Gabriella Farries , John A Browne , David E MacHugh , Grace Mulcahy

RNA-Seq Transcriptome Analysis of Peripheral Blood From Cattle Infected With

Frontiers in veterinary science

Avec: Kirsten E McLoughlin , Carolina N Correia , John A Browne , David A Magee , Nicolas C Nalpas , Kevin Rue-Albrecht , Adam O Whelan , Bernardo Villarreal-Ramos , H Martin Vordermeier , Eamonn Gormley , Stephen V Gordon , David E MacHugh

Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis.

Parasite immunology

Avec: Pamela A Kelly , Gillian P McHugo , Caitriona Scaife , Susan Peters , M Lynn Stevenson , Jennifer S McKay , David E MacHugh , Irene Lara Saez , Rory Breathnach

Integrative genomics analysis highlights functionally relevant genes for equine behaviour.

Animal genetics

Avec: Amy R Holtby , Thomas J Hall , Beatrice A McGivney , Haige Han , Keith J Murphy , David E MacHugh , Lisa M Katz , Emmeline W Hill

Expression Quantitative Trait Loci in Equine Skeletal Muscle Reveals Heritable Variation in Metabolism and the Training Responsive Transcriptome.

Frontiers in genetics

Avec: Gabriella Farries , Kenneth Bryan , Charlotte L McGivney , Paul A McGettigan , Katie F Gough , John A Browne , David E MacHugh , Lisa Michelle Katz , Emmeline W Hill

Functional analysis of the Mycobacterium bovis AF2122/97 PhoPR system.

Tuberculosis (Edinburgh, Scotland)

Avec: Jose Maria Urtasun-Elizari , Ruoyao Ma , Hayleah Pickford , Damien Farrell , Gabriel Gonzalez , Viktor Perets , Chie Nakajima , Yasuhiko Suzuki , David E MacHugh , Apoorva Bhatt , Stephen V Gordon

Recent selection and introgression facilitated high-altitude adaptation in cattle.

Science bulletin

Avec: Yang Lyu , Fuwen Wang , Haijian Cheng , Jing Han , Ruihua Dang , Xiaoting Xia , Hui Wang , Jincheng Zhong , Johannes A Lenstra , Hucai Zhang , Jianlin Han , David E MacHugh , Ivica Medugorac , Maulik Upadhyay , Alexander S Leonard , He Ding , Xiaorui Yang , Ming-Shan Wang , Suolang Quji , Basang Zhuzha , Pubu Quzhen , Silang Wangmu , Nima Cangjue , Da Wa , Weidong Ma , Jianyong Liu , Jicai Zhang , Bizhi Huang , Xingshan Qi , Fuqiang Li , Yongzhen Huang , Yun Ma , Yu Wang , Yuanpeng Gao , Wenfa Lu , Chuzhao Lei , Ningbo Chen

High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course.

Tuberculosis (Edinburgh, Scotland)

Avec: Carolina N Correia , Gillian P McHugo , John A Browne , Kirsten E McLoughlin , Nicolas C Nalpas , David A Magee , Adam O Whelan , Bernardo Villarreal-Ramos , H Martin Vordermeier , Eamonn Gormley , Stephen V Gordon , David E MacHugh

Genomic insights into the population history and adaptive traits of Latin American Criollo cattle.

Royal Society open science

Avec: James A Ward , Said I Ng'ang'a , Imtiaz A S Randhawa , Gillian P McHugo , John F O'Grady , Julio M Flórez , John A Browne , Ana M Pérez O'Brien , Antonio J Landaeta-Hernández , Jóse F Garcia , Tad S Sonstegard , Laurent A F Frantz , Michael Salter-Townshend , David E MacHugh

Selection in Australian Thoroughbred horses acts on a locus associated with early two-year old speed.

PloS one

Avec: Haige Han , Beatrice A McGivney , Gabriella Farries , Lisa M Katz , David E MacHugh , Imtiaz A S Randhawa , Emmeline W Hill

Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent.

Science (New York, N.Y.)

Avec: Marta Pereira Verdugo , Victoria E Mullin , Amelie Scheu , Valeria Mattiangeli , Kevin G Daly , Pierpaolo Maisano Delser , Andrew J Hare , Joachim Burger , Matthew J Collins , Ron Kehati , Paula Hesse , Deirdre Fulton , Eberhard W Sauer , Fatemeh A Mohaseb , Hossein Davoudi , Roya Khazaeli , Johanna Lhuillier , Claude Rapin , Saeed Ebrahimi , Mutalib Khasanov , S M Farhad Vahidi , David E MacHugh , Okan Ertuğrul , Chaido Koukouli-Chrysanthaki , Adamantios Sampson , George Kazantzis , Ioannis Kontopoulos , Jelena Bulatovic , Ivana Stojanović , Abdesalam Mikdad , Norbert Benecke , Jörg Linstädter , Mikhail Sablin , Robin Bendrey , Lionel Gourichon , Benjamin S Arbuckle , Marjan Mashkour , David Orton , Liora Kolska Horwitz , Matthew D Teasdale , Daniel G Bradley

A Population Genomics Analysis of the Native Irish Galway Sheep Breed.

Frontiers in genetics

Avec: Gillian P McHugo , Sam Browett , Imtiaz A S Randhawa , Dawn J Howard , Michael P Mullen , Ian W Richardson , Stephen D E Park , David A Magee , Erik Scraggs , Michael J Dover , Carolina N Correia , James P Hanrahan , David E MacHugh

Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria.

BMC genomics

Avec: Thomas J Hall , Michael P Mullen , Gillian P McHugo , Kate E Killick , Siobhán C Ring , Donagh P Berry , Carolina N Correia , John A Browne , Stephen V Gordon , David E MacHugh

Identification of novel molecular markers of mastitis caused by

Journal of animal science and biotechnology

Avec: Di Wang , Lei Liu , Serafino M A Augustino , Tao Duan , Thomas J Hall , David E MacHugh , Jinhuan Dou , Yi Zhang , Yachun Wang , Ying Yu

Transcriptome profiling of differentiating adipose-derived stem cells across species reveals new genes regulating adipogenesis.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Jiangang Han , Xiaojie Li , Benmeng Liang , Sijia Ma , Yabin Pu , Fuqing Yu , Jian Lu , Yuehui Ma , David E MacHugh , Lin Jiang

Inbreeding depression and durability in the North American Thoroughbred horse.

Animal genetics

Avec: Emmeline W Hill , Beatrice A McGivney , David E MacHugh

Genomic inbreeding trends, influential sire lines and selection in the global Thoroughbred horse population.

Scientific reports

Avec: Beatrice A McGivney , Haige Han , Leanne R Corduff , Lisa M Katz , Teruaki Tozaki , David E MacHugh , Emmeline W Hill

Refinement of Global Domestic Horse Biogeography Using Historic Landrace Chinese Mongolian Populations.

The Journal of heredity

Avec: Haige Han , Kenneth Bryan , Wunierfu Shiraigol , Dongyi Bai , Yiping Zhao , Wuyingga Bao , Siqin Yang , Wengang Zhang , David E MacHugh , Manglai Dugarjaviin , Emmeline W Hill

A genomic prediction model for racecourse starts in the Thoroughbred horse.

Animal genetics

Avec: B A McGivney , B Hernandez , L M Katz , D E MacHugh , S P McGovern , A C Parnell , H L Wiencko , E W Hill

The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis.

Scientific reports

Avec: Alan Mark O'Doherty , Kevin Christophe Rue-Albrecht , David Andrew Magee , Simone Ahting , Rachelle Elizabeth Irwin , Thomas Jonathan Hall , John Arthur Browne , Nicolas Claude Nalpas , Colum Patrick Walsh , Stephen Vincent Gordon , Marcin Włodzimierz Wojewodzic , David Evan MacHugh

Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics.

BMC biology

Avec: Gillian P McHugo , Michael J Dover , David E MacHugh

Integrative and comparative genomic analyses of mammalian macrophage responses to intracellular mycobacterial pathogens.

Tuberculosis (Edinburgh, Scotland)

Avec: Thomas J Hall , Gillian P McHugo , Michael P Mullen , James A Ward , Kate E Killick , John A Browne , Stephen V Gordon , David E MacHugh

Preferential differential gene expression within the WC1.1

Frontiers in immunology

Avec: Sajad A Bhat , Mahmoud Elnaggar , Thomas J Hall , Gillian P McHugo , Cian Reid , David E MacHugh , Kieran G Meade

Transcriptomics analysis of the bovine endometrium during the perioestrus period.

PloS one

Avec: Mohammed A Alfattah , Carolina N Correia , John A Browne , Paul A McGettigan , Katarzyna Pluta , Stephen D Carrington , David E MacHugh , Jane A Irwin

Analysis of genetic variation contributing to measured speed in Thoroughbreds identifies genomic regions involved in the transcriptional response to exercise.

Animal genetics

Avec: G Farries , K F Gough , A C Parnell , B A McGivney , C L McGivney , P A McGettigan , D E MacHugh , L M Katz , E W Hill

Chinese Mongolian horses may retain early domestic male genetic lineages yet to be discovered.

Animal genetics

Avec: H Han , B Wallner , D Rigler , D E MacHugh , D Manglai , E W Hill

Domestication of cattle: Two or three events?

Evolutionary applications

Avec: Daniel Pitt , Natalia Sevane , Ezequiel L Nicolazzi , David E MacHugh , Stephen D E Park , Licia Colli , Rodrigo Martinez , Michael W Bruford , Pablo Orozco-terWengel

The contribution of myostatin (MSTN) and additional modifying genetic loci to race distance aptitude in Thoroughbred horses racing in different geographic regions.

Equine veterinary journal

Avec: E W Hill , B A McGivney , M F Rooney , L M Katz , A Parnell , D E MacHugh

Alveolar Macrophage Chromatin Is Modified to Orchestrate Host Response to

Frontiers in genetics

Avec: Thomas J Hall , Douglas Vernimmen , John A Browne , Michael P Mullen , Stephen V Gordon , David E MacHugh , Alan M O'Doherty

Timing of Transcriptomic Peripheral Blood Mononuclear Cell Responses of Sheep to

Frontiers in immunology

Avec: Dagmara A Niedziela , Amalia Naranjo-Lucena , Verónica Molina-Hernández , John A Browne , Álvaro Martínez-Moreno , José Pérez , David E MacHugh , Grace Mulcahy

Transcriptome Profiling of Developing Ovine Fat Tail Tissue Reveals an Important Role for

Frontiers in cell and developmental biology

Avec: Jiangang Han , Sijia Ma , Benmeng Liang , Tianyou Bai , Yuhetian Zhao , Yuehui Ma , David E MacHugh , Lina Ma , Lin Jiang

Inbreeding depression and the probability of racing in the Thoroughbred horse.

Proceedings. Biological sciences

Avec: Emmeline W Hill , Martin A Stoffel , Beatrice A McGivney , David E MacHugh , Josephine M Pemberton

Genome-wide local ancestry and evidence for mitonuclear coadaptation in African hybrid cattle populations.

iScience

Avec: James A Ward , Gillian P McHugo , Michael J Dover , Thomas J Hall , Said Ismael Ng'ang'a , Tad S Sonstegard , Daniel G Bradley , Laurent A F Frantz , Michael Salter-Townshend , David E MacHugh

Common protein-coding variants influence the racing phenotype in galloping racehorse breeds.

Communications biology

Avec: Haige Han , Beatrice A McGivney , Lucy Allen , Dongyi Bai , Leanne R Corduff , Gantulga Davaakhuu , Jargalsaikhan Davaasambuu , Dulguun Dorjgotov , Thomas J Hall , Andrew J Hemmings , Amy R Holtby , Tuyatsetseg Jambal , Badarch Jargalsaikhan , Uyasakh Jargalsaikhan , Naveen K Kadri , David E MacHugh , Hubert Pausch , Carol Readhead , David Warburton , Manglai Dugarjaviin , Emmeline W Hill

Selection signatures for local and regional adaptation in Chinese Mongolian horse breeds reveal candidate genes for hoof health.

BMC genomics

Avec: Haige Han , Imtiaz A S Randhawa , David E MacHugh , Beatrice A McGivney , Lisa M Katz , Manglai Dugarjaviin , Emmeline W Hill

Réseau de co-auteurs

John A Browne 10 collaborations

Gillian P McHugo 9 collaborations

Emmeline W Hill 9 collaborations

Thomas J Hall 8 collaborations

Beatrice A McGivney 7 collaborations

Carolina N Correia 6 collaborations

Stephen V Gordon 6 collaborations

Haige Han 6 collaborations

Lisa M Katz 4 collaborations

Imtiaz A S Randhawa 4 collaborations

Michael P Mullen 4 collaborations

D E MacHugh 4 collaborations

E W Hill 4 collaborations

Gabriella Farries 3 collaborations

David A Magee 3 collaborations

James A Ward 3 collaborations

Michael J Dover 3 collaborations

Manglai Dugarjaviin 3 collaborations

B A McGivney 3 collaborations

L M Katz 3 collaborations

Amalia Naranjo-Lucena 2 collaborations

Grace Mulcahy 2 collaborations

Kirsten E McLoughlin 2 collaborations

Nicolas C Nalpas 2 collaborations

Adam O Whelan 2 collaborations

Bernardo Villarreal-Ramos 2 collaborations

H Martin Vordermeier 2 collaborations

Eamonn Gormley 2 collaborations

Amy R Holtby 2 collaborations

Kenneth Bryan 2 collaborations

Paul A McGettigan 2 collaborations

Tad S Sonstegard 2 collaborations

Laurent A F Frantz 2 collaborations

Michael Salter-Townshend 2 collaborations

Daniel G Bradley 2 collaborations

Stephen D E Park 2 collaborations

Kate E Killick 2 collaborations

Jiangang Han 2 collaborations

Benmeng Liang 2 collaborations

Sijia Ma 2 collaborations

Yuehui Ma 2 collaborations

Lin Jiang 2 collaborations

Leanne R Corduff 2 collaborations

Dongyi Bai 2 collaborations

A C Parnell 2 collaborations

Andres Garcia-Campos 1 collaboration

Laura Garza-Cuartero 1 collaboration

Kevin Rue-Albrecht 1 collaboration

Pamela A Kelly 1 collaboration

Caitriona Scaife 1 collaboration

Susan Peters 1 collaboration

M Lynn Stevenson 1 collaboration

Jennifer S McKay 1 collaboration

Irene Lara Saez 1 collaboration

Rory Breathnach 1 collaboration

Keith J Murphy 1 collaboration

Charlotte L McGivney 1 collaboration

Katie F Gough 1 collaboration

Lisa Michelle Katz 1 collaboration

Jose Maria Urtasun-Elizari 1 collaboration

Ruoyao Ma 1 collaboration

Hayleah Pickford 1 collaboration

Damien Farrell 1 collaboration

Gabriel Gonzalez 1 collaboration

Viktor Perets 1 collaboration

Chie Nakajima 1 collaboration

Yasuhiko Suzuki 1 collaboration

Apoorva Bhatt 1 collaboration

Yang Lyu 1 collaboration

Fuwen Wang 1 collaboration

Haijian Cheng 1 collaboration

Jing Han 1 collaboration

Ruihua Dang 1 collaboration

Xiaoting Xia 1 collaboration

Hui Wang 1 collaboration

Jincheng Zhong 1 collaboration

Johannes A Lenstra 1 collaboration

Hucai Zhang 1 collaboration

Jianlin Han 1 collaboration

Ivica Medugorac 1 collaboration

Maulik Upadhyay 1 collaboration

Alexander S Leonard 1 collaboration

He Ding 1 collaboration

Xiaorui Yang 1 collaboration

Ming-Shan Wang 1 collaboration

Suolang Quji 1 collaboration

Basang Zhuzha 1 collaboration

Pubu Quzhen 1 collaboration

Silang Wangmu 1 collaboration

Nima Cangjue 1 collaboration

Da Wa 1 collaboration

Weidong Ma 1 collaboration

Jianyong Liu 1 collaboration

Jicai Zhang 1 collaboration

Bizhi Huang 1 collaboration

Xingshan Qi 1 collaboration

Fuqiang Li 1 collaboration

Yongzhen Huang 1 collaboration

Yun Ma 1 collaboration

Yu Wang 1 collaboration

Yuanpeng Gao 1 collaboration

Wenfa Lu 1 collaboration

Chuzhao Lei 1 collaboration

Ningbo Chen 1 collaboration

Said I Ng'ang'a 1 collaboration

John F O'Grady 1 collaboration

Julio M Flórez 1 collaboration

Ana M Pérez O'Brien 1 collaboration

Antonio J Landaeta-Hernández 1 collaboration

Jóse F Garcia 1 collaboration

Marta Pereira Verdugo 1 collaboration

Victoria E Mullin 1 collaboration

Amelie Scheu 1 collaboration

Valeria Mattiangeli 1 collaboration

Kevin G Daly 1 collaboration

Pierpaolo Maisano Delser 1 collaboration

Andrew J Hare 1 collaboration

Joachim Burger 1 collaboration

Matthew J Collins 1 collaboration

Ron Kehati 1 collaboration

Paula Hesse 1 collaboration

Deirdre Fulton 1 collaboration

Eberhard W Sauer 1 collaboration

Fatemeh A Mohaseb 1 collaboration

Hossein Davoudi 1 collaboration

Roya Khazaeli 1 collaboration

Johanna Lhuillier 1 collaboration

Claude Rapin 1 collaboration

Saeed Ebrahimi 1 collaboration

Mutalib Khasanov 1 collaboration

S M Farhad Vahidi 1 collaboration

Okan Ertuğrul 1 collaboration

Chaido Koukouli-Chrysanthaki 1 collaboration

Adamantios Sampson 1 collaboration

George Kazantzis 1 collaboration

Ioannis Kontopoulos 1 collaboration

Jelena Bulatovic 1 collaboration

Ivana Stojanović 1 collaboration

Abdesalam Mikdad 1 collaboration

Norbert Benecke 1 collaboration

Jörg Linstädter 1 collaboration

Mikhail Sablin 1 collaboration

Robin Bendrey 1 collaboration

Lionel Gourichon 1 collaboration

Benjamin S Arbuckle 1 collaboration

Marjan Mashkour 1 collaboration

David Orton 1 collaboration

Liora Kolska Horwitz 1 collaboration

Matthew D Teasdale 1 collaboration

Sam Browett 1 collaboration

Dawn J Howard 1 collaboration

Ian W Richardson 1 collaboration

Erik Scraggs 1 collaboration

James P Hanrahan 1 collaboration

Siobhán C Ring 1 collaboration

Donagh P Berry 1 collaboration

Di Wang 1 collaboration

Lei Liu 1 collaboration

Serafino M A Augustino 1 collaboration

Tao Duan 1 collaboration

Jinhuan Dou 1 collaboration

Yi Zhang 1 collaboration

Yachun Wang 1 collaboration

Ying Yu 1 collaboration

Xiaojie Li 1 collaboration

Yabin Pu 1 collaboration

Fuqing Yu 1 collaboration

Jian Lu 1 collaboration

Teruaki Tozaki 1 collaboration

Wunierfu Shiraigol 1 collaboration

Yiping Zhao 1 collaboration

Wuyingga Bao 1 collaboration

Siqin Yang 1 collaboration

Wengang Zhang 1 collaboration

B Hernandez 1 collaboration

S P McGovern 1 collaboration

H L Wiencko 1 collaboration

Alan Mark O'Doherty 1 collaboration

Kevin Christophe Rue-Albrecht 1 collaboration

David Andrew Magee 1 collaboration

Simone Ahting 1 collaboration

Rachelle Elizabeth Irwin 1 collaboration

Thomas Jonathan Hall 1 collaboration

John Arthur Browne 1 collaboration

Nicolas Claude Nalpas 1 collaboration

Colum Patrick Walsh 1 collaboration

Stephen Vincent Gordon 1 collaboration

Marcin Włodzimierz Wojewodzic 1 collaboration

David Evan MacHugh 1 collaboration

Sajad A Bhat 1 collaboration

Mahmoud Elnaggar 1 collaboration

Cian Reid 1 collaboration

Kieran G Meade 1 collaboration

Mohammed A Alfattah 1 collaboration

Katarzyna Pluta 1 collaboration

Stephen D Carrington 1 collaboration

Jane A Irwin 1 collaboration

G Farries 1 collaboration

K F Gough 1 collaboration

C L McGivney 1 collaboration

P A McGettigan 1 collaboration

H Han 1 collaboration

B Wallner 1 collaboration

D Rigler 1 collaboration

D Manglai 1 collaboration

Daniel Pitt 1 collaboration

Natalia Sevane 1 collaboration

Ezequiel L Nicolazzi 1 collaboration

Licia Colli 1 collaboration

Rodrigo Martinez 1 collaboration

Michael W Bruford 1 collaboration

Pablo Orozco-terWengel 1 collaboration

M F Rooney 1 collaboration

A Parnell 1 collaboration

Douglas Vernimmen 1 collaboration

Alan M O'Doherty 1 collaboration

Dagmara A Niedziela 1 collaboration

Verónica Molina-Hernández 1 collaboration

Álvaro Martínez-Moreno 1 collaboration

José Pérez 1 collaboration

Tianyou Bai 1 collaboration

Yuhetian Zhao 1 collaboration

Lina Ma 1 collaboration

Martin A Stoffel 1 collaboration

Josephine M Pemberton 1 collaboration

Said Ismael Ng'ang'a 1 collaboration

Lucy Allen 1 collaboration

Gantulga Davaakhuu 1 collaboration

Jargalsaikhan Davaasambuu 1 collaboration

Dulguun Dorjgotov 1 collaboration

Andrew J Hemmings 1 collaboration

Tuyatsetseg Jambal 1 collaboration

Badarch Jargalsaikhan 1 collaboration

Uyasakh Jargalsaikhan 1 collaboration

Naveen K Kadri 1 collaboration

Hubert Pausch 1 collaboration

Carol Readhead 1 collaboration

David Warburton 1 collaboration