Inbreeding depression and durability in the North American Thoroughbred horse.


Journal

Animal genetics
ISSN: 1365-2052
Titre abrégé: Anim Genet
Pays: England
ID NLM: 8605704

Informations de publication

Date de publication:
Jun 2023
Historique:
revised: 18 01 2023
received: 24 08 2022
accepted: 09 02 2023
medline: 3 5 2023
pubmed: 28 2 2023
entrez: 27 2 2023
Statut: ppublish

Résumé

The proportion of the genome containing runs of homozygosity (ROH) affects production traits in livestock populations. In European and Australasian Thoroughbreds inbreeding, quantified using ROH (F

Identifiants

pubmed: 36843349
doi: 10.1111/age.13309
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

408-411

Subventions

Organisme : Science Foundation Ireland
ID : 11/PI/1166
Pays : Ireland

Informations de copyright

© 2023 The Authors. Animal Genetics published by John Wiley & Sons Ltd on behalf of Stichting International Foundation for Animal Genetics.

Références

116th United States Congress [2019-2020]. (2020) H.R.1754 - Horseracing Integrity and Safety Act of 2020. https://www.congress.gov/bill/116th-congress/house-bill/1754/text
Bates, D., Mächler, M., Bolker, B. & Walker, S. (2015) Fitting linear mixed-effects models using lme4. Journal of Statistical Software, 67, 1-48.
Binns, M.M., Boehler, D.A., Bailey, E., Lear, T.L., Cardwell, J.M. & Lambert, D.H. (2012) Inbreeding in the thoroughbred horse. Animal Genetics, 43, 340-342.
Han, H., McGivney, B.A., Farries, G., Katz, L.M., MacHugh, D.E., Randhawa, I.A.S. et al. (2020) Selection in Australian thoroughbred horses acts on a locus associated with early two-year old speed. PLoS One, 15, e0227212.
Hill, E.W., Stoffel, M.A., McGivney, B.A., MacHugh, D.E. & Pemberton, J.M. (2022) Inbreeding depression and the probability of racing in the thoroughbred horse. Proceedings: Biological Sciences, the Royal Society, 289, 20220487.
Horse Racing Ireland. (2021) Horse racing Ireland Factbook 2021. Kildare, Ireland: The Curragh. https://www.hri.ie/hri/2021/HRI%20Factbook%202021%20FINAL.pdf
Lampi, S., Donner, J., Anderson, H. & Pohjoismaki, J. (2020) Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages. Canine Med Genetics, 7, 5.
McGivney, B.A., Han, H., Corduff, L.R., Katz, L.M., Tozaki, T., MacHugh, D.E. et al. (2020) Genomic inbreeding trends, influential sire lines and selection in the global thoroughbred horse population. Scientific Reports, 10, 466.
McQuillan, R., Leutenegger, A.L., Abdel-Rahman, R., Franklin, C.S., Pericic, M., Barac-Lauc, L. et al. (2008) Runs of homozygosity in European populations. American Journal of Human Genetics, 83, 359-372.
Orlando, L. & Librado, P. (2019) Origin and evolution of deleterious mutations in horses. Genes (Basel), 10.
Petersen, J.L., Mickelson, J.R., Cothran, E.G., Andersson, L.S., Axelsson, J., Bailey, E. et al. (2013) Genetic diversity in the modern horse illustrated from genome-wide SNP data. PLoS One, 8, e54997.
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M.A., Bender, D. et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. American Journal of Human Genetics, 81, 559-575.
The Jockey Club. (2022) 2022 Fact book. New York, NY, USA: The Jockey Club. https://www.jockeyclub.com/Default.asp?section=Resources&area=11
Todd, E.T., Ho, S.Y.W., Thomson, P.C., Ang, R.A., Velie, B.D. & Hamilton, N.A. (2018) Founder-specific inbreeding depression affects racing performance in thoroughbred horses. Scientific Reports, 8, 6167.
Wade, C.M., Giulotto, E., Sigurdsson, S., Zoli, M., Gnerre, S., Imsland, F. et al. (2009) Genome sequence, comparative analysis, and population genetics of the domestic horse. Science, 326, 865-867.

Auteurs

Emmeline W Hill (EW)

Plusvital Ltd., The Highline, Dun Laoghaire Industrial Estate, Dublin, Ireland.
UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.

Beatrice A McGivney (BA)

Plusvital Ltd., The Highline, Dun Laoghaire Industrial Estate, Dublin, Ireland.

David E MacHugh (DE)

UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

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Classifications MeSH