David Rageot

Affiliations

Centre de Recherche INSERM LNC-UMR1231, Dijon, France; Cancer Biology Transfer Platform, Centre Georges-François Leclerc, Dijon, France.

Publications (14)

A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR Inhibitor.

Journal of medicinal chemistry

Avec: Chiara Borsari , Denise Rageot , Alix Dall'Asen , Thomas Bohnacker , Anna Melone , Alexander M Sele , Eileen Jackson , Jean-Baptiste Langlois , Florent Beaufils , Paul Hebeisen , Doriano Fabbro , Petra Hillmann , Matthias P Wymann

Machine learning evaluation of immune infiltrate through digital tumour score allows prediction of survival outcome in a pooled analysis of three international stage III colon cancer cohorts.

EBioMedicine

Avec: Julie Lecuelle , Caroline Truntzer , Debora Basile , Luigi Laghi , Luana Greco , Alis Ilie , David Rageot , Jean-François Emile , Fréderic Bibeau , Julien Taïeb , Valentin Derangere , Come Lepage , François Ghiringhelli

The Endogenous Inhibitor of CETP, apoC1, Remains Ineffective In Vivo after Correction of Hyperglycemia in People with Type 1 Diabetes.

Metabolites

Avec: Alexia Rouland , Thomas Gautier , Damien Denimal , Laurence Duvillard , Isabelle Simoneau , David Rageot , Bruno Vergès , Benjamin Bouillet

Brain-penetrant PQR620 mTOR and PQR530 PI3K/mTOR inhibitor reduce huntingtin levels in cell models of HD.

Neuropharmacology

Avec: Elisabeth Singer , Carolin Walter , Doriano Fabbro , Denise Rageot , Florent Beaufils , Matthias P Wymann , Nadine Rischert , Olaf Riess , Petra Hillmann , Huu Phuc Nguyen

Using a convolutional neural network for classification of squamous and non-squamous non-small cell lung cancer based on diagnostic histopathology HES images.

Scientific reports

Avec: Anne Laure Le Page , Elise Ballot , Caroline Truntzer , Valentin Derangère , Alis Ilie , David Rageot , Frederic Bibeau , Francois Ghiringhelli

CD3-CD8 immune score associated with a clinical score stratifies PDAC prognosis regardless of adjuvant or neoadjuvant chemotherapy.

Oncoimmunology

Avec: Coralie Schoumacher , Valentin Derangère , Gwladys Gaudillière-Le Dain , Titouan Huppe , David Rageot , Alis Ilie , Angélique Vienot , Christophe Borg , Franck Monnien , Frederic Bibeau , Caroline Truntzer , François Ghiringhelli , Auteur inconnu

The Novel TORC1/2 Kinase Inhibitor PQR620 Has Anti-Tumor Activity in Lymphomas as a Single Agent and in Combination with Venetoclax.

Cancers

Avec: Chiara Tarantelli , Eugenio Gaudio , Petra Hillmann , Filippo Spriano , Giulio Sartori , Luca Aresu , Luciano Cascione , Denise Rageot , Ivo Kwee , Florent Beaufils , Emanuele Zucca , Anastasios Stathis , Matthias P Wymann , Vladimir Cmiljanovic , Doriano Fabbro , Francesco Bertoni

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Journal of medicinal chemistry

Avec: Denise Rageot , Thomas Bohnacker , Erhan Keles , Jacob A McPhail , Reece M Hoffmann , Anna Melone , Chiara Borsari , Rohitha Sriramaratnam , Alexander M Sele , Florent Beaufils , Paul Hebeisen , Doriano Fabbro , Petra Hillmann , John E Burke , Matthias P Wymann

Preclinical Development of PQR514, a Highly Potent PI3K Inhibitor Bearing a Difluoromethyl-Pyrimidine Moiety.

ACS medicinal chemistry letters

Avec: Chiara Borsari , Denise Rageot , Florent Beaufils , Thomas Bohnacker , Erhan Keles , Ivan Buslov , Anna Melone , Alexander M Sele , Paul Hebeisen , Doriano Fabbro , Petra Hillmann , Matthias P Wymann

Case report: Immune response characterization of a pseudoprogression in a PD-L1-negative, TMB-low,

Frontiers in immunology

Avec: Nicolas Roussot , Marion Thibaudin , Jean-David Fumet , Susy Daumoine , Léa Hampe , Cédric Rébé , Emeric Limagne , Aurélie Lagrange , Victor Herreros , Julie Lecuelle , Hugo Mananet , Alis Ilie , David Rageot , Romain Boidot , Vincent Goussot , Anthony Comte , Pierre Jacob , Françoise Beltjens , Anthony Bergeron , Céline Charon-Barra , Laurent Arnould , Valentin Derangère , Sylvain Ladoire , Caroline Truntzer , François Ghiringhelli

A Multicentre Pilot Study of a Two-Tier Newborn Sickle Cell Disease Screening Procedure with a First Tier Based on a Fully Automated MALDI-TOF MS Platform.

International journal of neonatal screening

Avec: Pierre Naubourg , Marven El Osta , David Rageot , Olivier Grunewald , Gilles Renom , Patrick Ducoroy , Jean-Marc Périni

4-(Difluoromethyl)-5-(4-((3

Journal of medicinal chemistry

Avec: Chiara Borsari , Erhan Keles , Denise Rageot , Andrea Treyer , Thomas Bohnacker , Lukas Bissegger , Martina De Pascale , Anna Melone , Rohitha Sriramaratnam , Florent Beaufils , Matthias Hamburger , Paul Hebeisen , Wolfgang Löscher , Doriano Fabbro , Petra Hillmann , Matthias P Wymann

Follicular helper-T cells restore CD8

Journal for immunotherapy of cancer

Avec: Julie Niogret , Hélène Berger , Cédric Rebe , Romain Mary , Elise Ballot , Caroline Truntzer , Marion Thibaudin , Valentin Derangère , Christophe Hibos , Léa Hampe , David Rageot , Théo Accogli , Philippe Joubert , Bertrand Routy , James Harker , Frederique Vegran , Francois Ghiringhelli , Fanny Chalmin

Combination of CDX2 H-score quantitative analysis with CD3 AI-guided analysis identifies patients with a good prognosis only in stage III colon cancer.

European journal of cancer (Oxford, England : 1990)

Avec: Valentin Derangère , Julie Lecuelle , Come Lepage , Oumaima Aoulad-Ben Salem , Ben M Allatessem , Alis Ilie , Olivier Bouché , Jean-Marc Phelip , Mathieu Baconnier , Denis Pezet , Virginie Sebbagh , Eric Terrebonne , Gauthier Bouard , Valérie Jooste , Anne-Marie Bouvier , Chloé Molimard , Franck Monnien , Daniel Gonzalez , Karine Le Malicot , David Rageot , Caroline Truntzer , Fréderic Bibeau , Francois Ghiringhelli , Auteur inconnu

Réseau de co-auteurs

Denise Rageot 6 collaborations

Florent Beaufils 6 collaborations

Doriano Fabbro 6 collaborations

Petra Hillmann 6 collaborations

Matthias P Wymann 6 collaborations

Caroline Truntzer 6 collaborations

Alis Ilie 5 collaborations

Valentin Derangère 5 collaborations

Chiara Borsari 4 collaborations

Thomas Bohnacker 4 collaborations

Anna Melone 4 collaborations

Paul Hebeisen 4 collaborations

Alexander M Sele 3 collaborations

Julie Lecuelle 3 collaborations

François Ghiringhelli 3 collaborations

Francois Ghiringhelli 3 collaborations

Erhan Keles 3 collaborations

Fréderic Bibeau 2 collaborations

Come Lepage 2 collaborations

Elise Ballot 2 collaborations

Frederic Bibeau 2 collaborations

Franck Monnien 2 collaborations

None None 2 collaborations

Rohitha Sriramaratnam 2 collaborations

Marion Thibaudin 2 collaborations

Léa Hampe 2 collaborations

Alix Dall'Asen 1 collaboration

Eileen Jackson 1 collaboration

Jean-Baptiste Langlois 1 collaboration

Debora Basile 1 collaboration

Luigi Laghi 1 collaboration

Luana Greco 1 collaboration

Jean-François Emile 1 collaboration

Julien Taïeb 1 collaboration

Valentin Derangere 1 collaboration

Alexia Rouland 1 collaboration

Thomas Gautier 1 collaboration

Damien Denimal 1 collaboration

Laurence Duvillard 1 collaboration

Isabelle Simoneau 1 collaboration

Bruno Vergès 1 collaboration

Benjamin Bouillet 1 collaboration

Elisabeth Singer 1 collaboration

Carolin Walter 1 collaboration

Nadine Rischert 1 collaboration

Olaf Riess 1 collaboration

Huu Phuc Nguyen 1 collaboration

Anne Laure Le Page 1 collaboration

Coralie Schoumacher 1 collaboration

Gwladys Gaudillière-Le Dain 1 collaboration

Titouan Huppe 1 collaboration

Angélique Vienot 1 collaboration

Christophe Borg 1 collaboration

Chiara Tarantelli 1 collaboration

Eugenio Gaudio 1 collaboration

Filippo Spriano 1 collaboration

Giulio Sartori 1 collaboration

Luca Aresu 1 collaboration

Luciano Cascione 1 collaboration

Ivo Kwee 1 collaboration

Emanuele Zucca 1 collaboration

Anastasios Stathis 1 collaboration

Vladimir Cmiljanovic 1 collaboration

Francesco Bertoni 1 collaboration

Jacob A McPhail 1 collaboration

Reece M Hoffmann 1 collaboration

John E Burke 1 collaboration

Ivan Buslov 1 collaboration

Nicolas Roussot 1 collaboration

Jean-David Fumet 1 collaboration

Susy Daumoine 1 collaboration

Cédric Rébé 1 collaboration

Emeric Limagne 1 collaboration

Aurélie Lagrange 1 collaboration

Victor Herreros 1 collaboration

Hugo Mananet 1 collaboration

Romain Boidot 1 collaboration

Vincent Goussot 1 collaboration

Anthony Comte 1 collaboration

Pierre Jacob 1 collaboration

Françoise Beltjens 1 collaboration

Anthony Bergeron 1 collaboration

Céline Charon-Barra 1 collaboration

Laurent Arnould 1 collaboration

Sylvain Ladoire 1 collaboration

Pierre Naubourg 1 collaboration

Marven El Osta 1 collaboration

Olivier Grunewald 1 collaboration

Gilles Renom 1 collaboration

Patrick Ducoroy 1 collaboration

Jean-Marc Périni 1 collaboration

Andrea Treyer 1 collaboration

Lukas Bissegger 1 collaboration

Martina De Pascale 1 collaboration

Matthias Hamburger 1 collaboration

Wolfgang Löscher 1 collaboration

Julie Niogret 1 collaboration

Hélène Berger 1 collaboration

Cédric Rebe 1 collaboration

Romain Mary 1 collaboration

Christophe Hibos 1 collaboration

Théo Accogli 1 collaboration

Philippe Joubert 1 collaboration

Bertrand Routy 1 collaboration

James Harker 1 collaboration

Frederique Vegran 1 collaboration

Fanny Chalmin 1 collaboration

Oumaima Aoulad-Ben Salem 1 collaboration

Ben M Allatessem 1 collaboration

Olivier Bouché 1 collaboration

Jean-Marc Phelip 1 collaboration

Mathieu Baconnier 1 collaboration

Denis Pezet 1 collaboration

Virginie Sebbagh 1 collaboration

Eric Terrebonne 1 collaboration

Gauthier Bouard 1 collaboration

Valérie Jooste 1 collaboration

Anne-Marie Bouvier 1 collaboration

Chloé Molimard 1 collaboration

Daniel Gonzalez 1 collaboration

Karine Le Malicot 1 collaboration