Demis Menolfi

Affiliations

Institute for Cancer Genetics, Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY, USA. dm3231@cumc.columbia.edu.
IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy. dm3231@cumc.columbia.edu.

Publications (13)

Using Cell Cycle-Restricted Alleles to Study the Chromatin Dynamics and Functions of the Structural Maintenance of Chromosomes (SMC) Complexes In Vivo.

Methods in molecular biology (Clifton, N.J.)

Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites.

Nature communications

Avec: Sumedha Agashe , Chinnu Rose Joseph , Teresa Anne Clarisse Reyes , Demis Menolfi , Michele Giannattasio , Anja Waizenegger , Barnabas Szakal , Dana Branzei

70 years of the DNA double helix: An interview with Daniela Rhodes.

Molecular cell

Avec: Demis Menolfi , Daniela Rhodes

Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.

bioRxiv : the preprint server for biology

Avec: Xiaohui Lin , Dipika Gupta , Alina Vaitsiankova , Seema Khattri Bhandari , Kay Sze Karina Leung , Demis Menolfi , Brian J Lee , Helen R Russell , Steven Gershik , Wei Gu , Peter J McKinnon , Françoise Dantzer , Eli Rothenberg , Alan E Tomkinson , Shan Zha

DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Xiaobin S Wang , Demis Menolfi , Foon Wu-Baer , Marco Fangazio , Stefanie N Meyer , Zhengping Shao , Yunyue Wang , Yimeng Zhu , Brian J Lee , Verna M Estes , Olivia M Cupo , Jean Gautier , Laura Pasqualucci , Riccardo Dalla-Favera , Richard Baer , Shan Zha

FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Maja Milanovic , Zhengping Shao , Verna M Estes , Xiaobin S Wang , Demis Menolfi , Xiaohui Lin , Brian J Lee , Jun Xu , Olivia M Cupo , Dong Wang , Shan Zha

Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.

Molecular cell

Avec: Xiaohui Lin , Dipika Gupta , Alina Vaitsiankova , Seema Khattri Bhandari , Kay Sze Karina Leung , Demis Menolfi , Brian J Lee , Helen R Russell , Steven Gershik , Xiaoyu Huang , Wei Gu , Peter J McKinnon , Françoise Dantzer , Eli Rothenberg , Alan E Tomkinson , Shan Zha

ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion.

Cell & bioscience

Avec: Demis Menolfi , Shan Zha

DNA-PKcs kinase activity orchestrates both end-processing and end-ligation.

Trends in cell biology

Avec: Demis Menolfi , Shan Zha

The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM Activation and Its Exchange.

Cancer research

Avec: Maja Milanovic , Lisa M Houghton , Demis Menolfi , Ji-Hoon Lee , Kenta Yamamoto , Yang Li , Brian J Lee , Jun Xu , Verna M Estes , Dong Wang , Peter J Mckinnon , Tanya T Paull , Shan Zha

Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements.

Nature

Avec: Zhiming Li , Shoufu Duan , Xu Hua , Xiaowei Xu , Yinglu Li , Demis Menolfi , Hui Zhou , Chao Lu , Shan Zha , Stephen P Goff , Zhiguo Zhang

ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.

bioRxiv : the preprint server for biology

Avec: Demis Menolfi , Brian J Lee , Hanwen Zhang , Wenxia Jiang , Nicole E Bowen , Yunyue Wang , Junfei Zhao , Antony Holmes , Steven Gershik , Raul Rabadan , Baek Kim , Shan Zha

ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.

Nature communications

Avec: Demis Menolfi , Brian J Lee , Hanwen Zhang , Wenxia Jiang , Nicole E Bowen , Yunyue Wang , Junfei Zhao , Antony Holmes , Steven Gershik , Raul Rabadan , Baek Kim , Shan Zha

Réseau de co-auteurs

Shan Zha 10 collaborations

Brian J Lee 7 collaborations

Steven Gershik 4 collaborations

Xiaohui Lin 3 collaborations

Yunyue Wang 3 collaborations

Verna M Estes 3 collaborations

Dana Branzei 2 collaborations

Dipika Gupta 2 collaborations

Alina Vaitsiankova 2 collaborations

Seema Khattri Bhandari 2 collaborations

Kay Sze Karina Leung 2 collaborations

Helen R Russell 2 collaborations

Wei Gu 2 collaborations

Peter J McKinnon 2 collaborations

Françoise Dantzer 2 collaborations

Eli Rothenberg 2 collaborations

Alan E Tomkinson 2 collaborations

Xiaobin S Wang 2 collaborations

Zhengping Shao 2 collaborations

Olivia M Cupo 2 collaborations

Maja Milanovic 2 collaborations

Jun Xu 2 collaborations

Dong Wang 2 collaborations

Hanwen Zhang 2 collaborations

Wenxia Jiang 2 collaborations

Nicole E Bowen 2 collaborations

Junfei Zhao 2 collaborations

Antony Holmes 2 collaborations

Raul Rabadan 2 collaborations

Baek Kim 2 collaborations

Sumedha Agashe 1 collaboration

Chinnu Rose Joseph 1 collaboration

Teresa Anne Clarisse Reyes 1 collaboration

Michele Giannattasio 1 collaboration

Anja Waizenegger 1 collaboration

Barnabas Szakal 1 collaboration

Daniela Rhodes 1 collaboration

Foon Wu-Baer 1 collaboration

Marco Fangazio 1 collaboration

Stefanie N Meyer 1 collaboration

Yimeng Zhu 1 collaboration

Jean Gautier 1 collaboration

Laura Pasqualucci 1 collaboration

Riccardo Dalla-Favera 1 collaboration

Richard Baer 1 collaboration

Xiaoyu Huang 1 collaboration

Lisa M Houghton 1 collaboration

Ji-Hoon Lee 1 collaboration

Kenta Yamamoto 1 collaboration

Yang Li 1 collaboration

Peter J Mckinnon 1 collaboration

Tanya T Paull 1 collaboration

Zhiming Li 1 collaboration

Shoufu Duan 1 collaboration

Xu Hua 1 collaboration

Xiaowei Xu 1 collaboration

Yinglu Li 1 collaboration

Hui Zhou 1 collaboration

Chao Lu 1 collaboration

Stephen P Goff 1 collaboration

Zhiguo Zhang 1 collaboration