Dimitrios Mathios

Affiliations

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Publications (27)

Detection and characterization of lung cancer using cell-free DNA fragmentomes.

Nature communications

Avec: Dimitrios Mathios , Jakob Sidenius Johansen , Stephen Cristiano , Jamie E Medina , Jillian Phallen , Klaus R Larsen , Daniel C Bruhm , Noushin Niknafs , Leonardo Ferreira , Vilmos Adleff , Jia Yuee Chiao , Alessandro Leal , Michael Noe , James R White , Adith S Arun , Carolyn Hruban , Akshaya V Annapragada , Sarah Østrup Jensen , Mai-Britt Worm Ørntoft , Anders Husted Madsen , Beatriz Carvalho , Meike de Wit , Jacob Carey , Nicholas C Dracopoli , Tara Maddala , Kenneth C Fang , Anne-Renee Hartman , Patrick M Forde , Valsamo Anagnostou , Julie R Brahmer , Remond J A Fijneman , Hans Jørgen Nielsen , Gerrit A Meijer , Claus Lindbjerg Andersen , Anders Mellemgaard , Stig E Bojesen , Robert B Scharpf , Victor E Velculescu

Genome-wide repeat landscapes in cancer and cell-free DNA.

Science translational medicine

Avec: Akshaya V Annapragada , Noushin Niknafs , James R White , Daniel C Bruhm , Christopher Cherry , Jamie E Medina , Vilmos Adleff , Carolyn Hruban , Dimitrios Mathios , Zachariah H Foda , Jillian Phallen , Robert B Scharpf , Victor E Velculescu

Tumor-informed deep sequencing of ctDNA detects minimal residual disease and predicts relapse in osteosarcoma.

EClinicalMedicine

Avec: Yiwei Fu , Yu Xu , Weihai Liu , Jiajun Zhang , Fen Wang , Qijie Jian , Gang Huang , Changye Zou , Xianbiao Xie , Albert H Kim , Dimitrios Mathios , Fei Pang , Feng Li , Kai Wang , Jingnan Shen , Junqiang Yin

Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types.

International journal of cancer

Avec: Dimitrios Mathios , Taeyoung Hwang , Yuanxuan Xia , Jillian Phallen , Yuan Rui , Alfred P See , Russell Maxwell , Zineb Belcaid , Joshua Casaos , Peter C Burger , Kerrie L McDonald , Gary L Gallia , Leslie Cope , Mihoko Kai , Henry Brem , Drew M Pardoll , Patrick Ha , Jordan J Green , Victor E Velculescu , Chetan Bettegowda , Chul-Kee Park , Michael Lim

Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment.

Journal of neuro-oncology

Avec: Adela Wu , Russell Maxwell , Yuanxuan Xia , Pina Cardarelli , Miho Oyasu , Zineb Belcaid , Eileen Kim , Alice Hung , Andrew S Luksik , Tomas Garzon-Muvdi , Christopher M Jackson , Dimitrios Mathios , Debebe Theodros , John Cogswell , Henry Brem , Drew M Pardoll , Michael Lim

Innovation in Non-Invasive Diagnosis and Disease Monitoring for Meningiomas.

International journal of molecular sciences

Avec: Brianna Korte , Dimitrios Mathios

Advances in molecular biomarkers and liquid biopsy in gliomas.

Neuro-oncology advances

Avec: Dimitrios Mathios , Jillian Phallen

Predictors of extent of resection and recurrence following endoscopic endonasal resection of craniopharyngioma.

Journal of neurosurgery

Avec: Ernest J Bobeff , Dimitrios Mathios , Adina A Mistry , Georgiana A Dobri , Mark M Souweidane , Vijay K Anand , Abtin Tabaee , Ashutosh Kacker , Jeffrey P Greenfield , Theodore H Schwartz

Low-dose oncolytic adenovirus therapy overcomes tumor-induced immune suppression and sensitizes intracranial gliomas to anti-PD-1 therapy.

Neuro-oncology advances

Avec: Zineb Belcaid , Cor Berrevoets , John Choi , Edward van Beelen , Eftychia Stavrakaki , Tessa Pierson , Jenneke Kloezeman , Denis Routkevitch , Mariëlle van der Kaaij , Alicia van der Ploeg , Dimitrios Mathios , Stefan Sleijfer , Clemens Dirven , Michael Lim , Reno Debets , Martine L M Lamfers

Treatment-refractory Escherichia coli subdural empyema caused by infection of a chronic subdural hematoma in an infant.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Avec: Jason A Chen , Dimitrios Mathios , Joaquin Hidalgo , Alan R Cohen

Emerging Technologies for Non-invasive Monitoring of Treatment Response to Immunotherapy for Brain Tumors.

Neuromolecular medicine

Avec: Dimitrios Mathios , Siddhartha Srivastava , Timothy Kim , Chetan Bettegowda , Michael Lim

Synthesizing Molecular and Immune Characteristics to Move Beyond WHO Grade in Meningiomas: A Focused Review.

Frontiers in oncology

Avec: Nivedha V Kannapadi , Pavan P Shah , Dimitrios Mathios , Christopher M Jackson

Cell-Free DNA Fragmentomes in the Diagnostic Evaluation of Patients With Symptoms Suggestive of Lung Cancer.

Chest

Avec: Alessandro I C Leal , Dimitrios Mathios , Debbie Jakubowski , Jakob S Johansen , Anna Lau , Tony Wu , Stephen Cristiano , Jamie E Medina , Jillian Phallen , Daniel C Bruhm , Jacob Carey , Nicholas C Dracopoli , Stig E Bojesen , Robert B Scharpf , Victor E Velculescu , Anil Vachani , Peter B Bach

DNA methylation and gene expression as determinants of genome-wide cell-free DNA fragmentation.

Nature communications

Avec: Michaël Noë , Dimitrios Mathios , Akshaya V Annapragada , Shashikant Koul , Zacharia H Foda , Jamie E Medina , Stephen Cristiano , Christopher Cherry , Daniel C Bruhm , Noushin Niknafs , Vilmos Adleff , Leonardo Ferreira , Hari Easwaran , Stephen Baylin , Jillian Phallen , Robert B Scharpf , Victor E Velculescu

Combination checkpoint therapy with anti-PD-1 and anti-BTLA results in a synergistic therapeutic effect against murine glioblastoma.

Oncoimmunology

Avec: John Choi , Ravi Medikonda , Laura Saleh , Timothy Kim , Ayush Pant , Siddhartha Srivastava , Young-Hoon Kim , Christina Jackson , Luqing Tong , Denis Routkevitch , Christopher Jackson , Dimitrios Mathios , Tianna Zhao , Hyerim Cho , Henry Brem , Michael Lim

Synergy between glutamate modulation and anti-programmed cell death protein 1 immunotherapy for glioblastoma.

Journal of neurosurgery

Avec: Ravi Medikonda , John Choi , Ayush Pant , Laura Saleh , Denis Routkevitch , Luqing Tong , Zineb Belcaid , Young Hoon Kim , Christopher M Jackson , Christina Jackson , Dimitrios Mathios , Yuanxuan Xia , Pavan P Shah , Kisha Patel , Timothy Kim , Siddhartha Srivastava , Sakibul Huq , Jeff Ehresman , Zach Pennington , Betty Tyler , Henry Brem , Michael Lim

Genotype-Phenotype Correlations in Neurofibromatosis and Their Potential Clinical Use.

Neurology

Avec: Chetan Bettegowda , Meena Upadhayaya , D Gareth Evans , AeRang Kim , Dimitrios Mathios , Clemens O Hanemann , Auteur inconnu

Durable headache relief following endoscopic endonasal resection of sub-centimeter Rathke cleft cysts in medically refractory patients.

Acta neurochirurgica

Avec: Dimitrios Mathios , Shejoy Joshua , Ernest J Bobeff , Adina A Mistry , Alexandra C Schwartz , Georgiana A Dobri , Abtin Tabaee , Ashutosh Kacker , Vijay K Anand , Theodore H Schwartz

Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma.

Acta neuropathologica communications

Avec: Taeyoung Hwang , Dimitrios Mathios , Kerrie L McDonald , Irene Daris , Sung-Hye Park , Peter C Burger , Sojin Kim , Yun-Sik Dho , Hruban Carolyn , Chetan Bettegowda , Joo Heon Shin , Michael Lim , Chul-Kee Park

New Prospects for Molecular Targets for Chordomas.

Neurosurgery clinics of North America

Avec: Mohammad Zeeshan Ozair , Pavan Pinkesh Shah , Dimitrios Mathios , Michael Lim , Nelson S Moss

Lateral Transorbital Approach for Repair of Lateral Sphenoid Sinus Meningoencephaloceles in Proximity to Foramen Rotundum: Cadaveric Study and Case Report.

Operative neurosurgery (Hagerstown, Md.)

Avec: Dimitrios Mathios , Ernest J Bobeff , Davide Longo , Abtin Tabaee , Vijay K Anand , Kyle J Godfrey , Theodore H Schwartz

Spinal cord untethering and midline myelotomy for delayed, symptomatic post-traumatic syringomyelia due to retained ballistic fragments: case report.

Spinal cord series and cases

Avec: Tej D Azad , Joshua Materi , Brian Y Hwang , Dimitrios Mathios , Kurt R Lehner , Landon Hansen , Lydia J Bernhardt , Yuanxuan Xia , Pavan P Shah , Nivedha V Kannapadi , Nicholas Theodore

Endoscopic odontoidectomy for brainstem compression in association with posterior fossa decompression and occipitocervical fusion.

Journal of neurosurgery

Avec: Umberto Tosi , Alexandra Giantini-Larsen , Dimitrios Mathios , Ashutosh Kacker , Vijay K Anand , Kiarash Ferdowssian , Ali Baaj , Roger Härtl , Benjamin I Rapoport , Jeffrey P Greenfield , Theodore H Schwartz

The lateral transorbital approach to the medial sphenoid wing, anterior clinoid, middle fossa, cavernous sinus, and Meckel's cave: target-based classification, approach-related complications, and intermediate-term ocular outcomes.

Journal of neurosurgery

Avec: Dimitrios Mathios , Ernest J Bobeff , Davide Longo , Parsa Nilchian , Joshua Estin , Alexandra C Schwartz , Quillan Austria , Vijay K Anand , Kyle J Godfrey , Theodore H Schwartz

Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer.

Nature genetics

Avec: Daniel C Bruhm , Dimitrios Mathios , Zachariah H Foda , Akshaya V Annapragada , Jamie E Medina , Vilmos Adleff , Elaine Jiayuee Chiao , Leonardo Ferreira , Stephen Cristiano , James R White , Sarah A Mazzilli , Ehab Billatos , Avrum Spira , Ali H Zaidi , Jeffrey Mueller , Amy K Kim , Valsamo Anagnostou , Jillian Phallen , Robert B Scharpf , Victor E Velculescu

Detecting Liver Cancer Using Cell-Free DNA Fragmentomes.

Cancer discovery

Avec: Zachariah H Foda , Akshaya V Annapragada , Kavya Boyapati , Daniel C Bruhm , Nicholas A Vulpescu , Jamie E Medina , Dimitrios Mathios , Stephen Cristiano , Noushin Niknafs , Harry T Luu , Michael G Goggins , Robert A Anders , Jing Sun , Shruti H Meta , David L Thomas , Gregory D Kirk , Vilmos Adleff , Jillian Phallen , Robert B Scharpf , Amy K Kim , Victor E Velculescu

Early detection of ovarian cancer using cell-free DNA fragmentomes and protein biomarkers.

Cancer discovery

Avec: Jamie E Medina , Akshaya V Annapragada , Pien Lof , Sarah Short , Adrianna L Bartolomucci , Dimitrios Mathios , Shashikant Koul , Noushin Niknafs , Michael Noe , Zachariah H Foda , Daniel C Bruhm , Carolyn Hruban , Nicholas A Vulpescu , Euihye Jung , Renu Dua , Jenna V Canzoniero , Stephen Cristiano , Vilmos Adleff , Heather Symecko , Daan van den Broek , Lori J Sokoll , Stephen B Baylin , Michael F Press , Dennis J Slamon , Gottfried E Konecny , Christina Therkildsen , Beatriz Carvalho , Gerrit A Meijer , Claus Lindbjerg Andersen , Susan M Domchek , Ronny Drapkin , Robert B Scharpf , Jillian Phallen , Christine A R Lok , Victor E Velculescu

Réseau de co-auteurs

Jillian Phallen 9 collaborations

Victor E Velculescu 8 collaborations

Michael Lim 8 collaborations

Jamie E Medina 7 collaborations

Daniel C Bruhm 7 collaborations

Robert B Scharpf 7 collaborations

Stephen Cristiano 6 collaborations

Vilmos Adleff 6 collaborations

Akshaya V Annapragada 6 collaborations

Noushin Niknafs 5 collaborations

Vijay K Anand 5 collaborations

Theodore H Schwartz 5 collaborations

Zachariah H Foda 4 collaborations

Yuanxuan Xia 4 collaborations

Zineb Belcaid 4 collaborations

Henry Brem 4 collaborations

Chetan Bettegowda 4 collaborations

Ernest J Bobeff 4 collaborations

Leonardo Ferreira 3 collaborations

James R White 3 collaborations

Carolyn Hruban 3 collaborations

Christopher M Jackson 3 collaborations

Abtin Tabaee 3 collaborations

Ashutosh Kacker 3 collaborations

John Choi 3 collaborations

Denis Routkevitch 3 collaborations

Siddhartha Srivastava 3 collaborations

Timothy Kim 3 collaborations

Pavan P Shah 3 collaborations

Michael Noe 2 collaborations

Beatriz Carvalho 2 collaborations

Jacob Carey 2 collaborations

Nicholas C Dracopoli 2 collaborations

Valsamo Anagnostou 2 collaborations

Gerrit A Meijer 2 collaborations

Claus Lindbjerg Andersen 2 collaborations

Stig E Bojesen 2 collaborations

Christopher Cherry 2 collaborations

Taeyoung Hwang 2 collaborations

Russell Maxwell 2 collaborations

Peter C Burger 2 collaborations

Kerrie L McDonald 2 collaborations

Drew M Pardoll 2 collaborations

Chul-Kee Park 2 collaborations

Adina A Mistry 2 collaborations

Georgiana A Dobri 2 collaborations

Jeffrey P Greenfield 2 collaborations

Nivedha V Kannapadi 2 collaborations

Shashikant Koul 2 collaborations

Ravi Medikonda 2 collaborations

Laura Saleh 2 collaborations

Ayush Pant 2 collaborations

Christina Jackson 2 collaborations

Luqing Tong 2 collaborations

Alexandra C Schwartz 2 collaborations

Davide Longo 2 collaborations

Kyle J Godfrey 2 collaborations

Amy K Kim 2 collaborations

Nicholas A Vulpescu 2 collaborations

Jakob Sidenius Johansen 1 collaboration

Klaus R Larsen 1 collaboration

Jia Yuee Chiao 1 collaboration

Alessandro Leal 1 collaboration

Adith S Arun 1 collaboration

Sarah Østrup Jensen 1 collaboration

Mai-Britt Worm Ørntoft 1 collaboration

Anders Husted Madsen 1 collaboration

Meike de Wit 1 collaboration

Tara Maddala 1 collaboration

Kenneth C Fang 1 collaboration

Anne-Renee Hartman 1 collaboration

Patrick M Forde 1 collaboration

Julie R Brahmer 1 collaboration

Remond J A Fijneman 1 collaboration

Hans Jørgen Nielsen 1 collaboration

Anders Mellemgaard 1 collaboration

Yiwei Fu 1 collaboration

Yu Xu 1 collaboration

Weihai Liu 1 collaboration

Jiajun Zhang 1 collaboration

Fen Wang 1 collaboration

Qijie Jian 1 collaboration

Gang Huang 1 collaboration

Changye Zou 1 collaboration

Xianbiao Xie 1 collaboration

Albert H Kim 1 collaboration

Fei Pang 1 collaboration

Feng Li 1 collaboration

Kai Wang 1 collaboration

Jingnan Shen 1 collaboration

Junqiang Yin 1 collaboration

Yuan Rui 1 collaboration

Alfred P See 1 collaboration

Joshua Casaos 1 collaboration

Gary L Gallia 1 collaboration

Leslie Cope 1 collaboration

Mihoko Kai 1 collaboration

Patrick Ha 1 collaboration

Jordan J Green 1 collaboration

Adela Wu 1 collaboration

Pina Cardarelli 1 collaboration

Miho Oyasu 1 collaboration

Eileen Kim 1 collaboration

Alice Hung 1 collaboration

Andrew S Luksik 1 collaboration

Tomas Garzon-Muvdi 1 collaboration

Debebe Theodros 1 collaboration

John Cogswell 1 collaboration

Brianna Korte 1 collaboration

Mark M Souweidane 1 collaboration

Cor Berrevoets 1 collaboration

Edward van Beelen 1 collaboration

Eftychia Stavrakaki 1 collaboration

Tessa Pierson 1 collaboration

Jenneke Kloezeman 1 collaboration

Mariëlle van der Kaaij 1 collaboration

Alicia van der Ploeg 1 collaboration

Stefan Sleijfer 1 collaboration

Clemens Dirven 1 collaboration

Reno Debets 1 collaboration

Martine L M Lamfers 1 collaboration

Jason A Chen 1 collaboration

Joaquin Hidalgo 1 collaboration

Alan R Cohen 1 collaboration

Alessandro I C Leal 1 collaboration

Debbie Jakubowski 1 collaboration

Jakob S Johansen 1 collaboration

Anna Lau 1 collaboration

Tony Wu 1 collaboration

Anil Vachani 1 collaboration

Peter B Bach 1 collaboration

Michaël Noë 1 collaboration

Zacharia H Foda 1 collaboration

Hari Easwaran 1 collaboration

Stephen Baylin 1 collaboration

Young-Hoon Kim 1 collaboration

Christopher Jackson 1 collaboration

Tianna Zhao 1 collaboration

Hyerim Cho 1 collaboration

Young Hoon Kim 1 collaboration

Kisha Patel 1 collaboration

Sakibul Huq 1 collaboration

Jeff Ehresman 1 collaboration

Zach Pennington 1 collaboration

Betty Tyler 1 collaboration

Meena Upadhayaya 1 collaboration

D Gareth Evans 1 collaboration

AeRang Kim 1 collaboration

Clemens O Hanemann 1 collaboration

None None 1 collaboration

Shejoy Joshua 1 collaboration

Irene Daris 1 collaboration

Sung-Hye Park 1 collaboration

Sojin Kim 1 collaboration

Yun-Sik Dho 1 collaboration

Hruban Carolyn 1 collaboration

Joo Heon Shin 1 collaboration

Mohammad Zeeshan Ozair 1 collaboration

Pavan Pinkesh Shah 1 collaboration

Nelson S Moss 1 collaboration

Tej D Azad 1 collaboration

Joshua Materi 1 collaboration

Brian Y Hwang 1 collaboration

Kurt R Lehner 1 collaboration

Landon Hansen 1 collaboration

Lydia J Bernhardt 1 collaboration

Nicholas Theodore 1 collaboration

Umberto Tosi 1 collaboration

Alexandra Giantini-Larsen 1 collaboration

Kiarash Ferdowssian 1 collaboration

Ali Baaj 1 collaboration

Roger Härtl 1 collaboration

Benjamin I Rapoport 1 collaboration

Parsa Nilchian 1 collaboration

Joshua Estin 1 collaboration

Quillan Austria 1 collaboration

Elaine Jiayuee Chiao 1 collaboration

Sarah A Mazzilli 1 collaboration

Ehab Billatos 1 collaboration

Avrum Spira 1 collaboration

Ali H Zaidi 1 collaboration

Jeffrey Mueller 1 collaboration

Kavya Boyapati 1 collaboration

Harry T Luu 1 collaboration

Michael G Goggins 1 collaboration

Robert A Anders 1 collaboration

Jing Sun 1 collaboration

Shruti H Meta 1 collaboration

David L Thomas 1 collaboration

Gregory D Kirk 1 collaboration

Pien Lof 1 collaboration

Sarah Short 1 collaboration

Adrianna L Bartolomucci 1 collaboration

Euihye Jung 1 collaboration

Renu Dua 1 collaboration

Jenna V Canzoniero 1 collaboration

Heather Symecko 1 collaboration

Daan van den Broek 1 collaboration

Lori J Sokoll 1 collaboration

Stephen B Baylin 1 collaboration

Michael F Press 1 collaboration

Dennis J Slamon 1 collaboration

Gottfried E Konecny 1 collaboration

Christina Therkildsen 1 collaboration

Susan M Domchek 1 collaboration

Ronny Drapkin 1 collaboration

Christine A R Lok 1 collaboration