Dorian M Cheff

Affiliations

National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.

Publications (9)

Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences.

SLAS discovery : advancing life sciences R & D

Avec: Jacob S Roth , Tobie D Lee , Dorian M Cheff , Maya L Gosztyla , Rosita R Asawa , Carina Danchik , Sam Michael , Anton Simeonov , Carleen Klumpp-Thomas , Kelli M Wilson , Matthew D Hall

Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties.

Journal of medicinal chemistry

Avec: Ganesha Rai , Daniel J Urban , Bryan T Mott , Xin Hu , Shyh-Ming Yang , Gloria A Benavides , Michelle S Johnson , Giuseppe L Squadrito , Kyle R Brimacombe , Tobie D Lee , Dorian M Cheff , Hu Zhu , Mark J Henderson , Katherine Pohida , Gary A Sulikowski , David M Dranow , Md Kabir , Pranav Shah , Elias Padilha , Dingyin Tao , Yuhong Fang , Plamen P Christov , Kwangho Kim , Somnath Jana , Pavan Muttil , Tamara Anderson , Nitesh K Kunda , Helen J Hathaway , Donna F Kusewitt , Nobu Oshima , Murali Cherukuri , Douglas R Davies , Jeffrey P Norenberg , Larry A Sklar , William J Moore , Chi V Dang , Gordon M Stott , Leonard Neckers , Andrew J Flint , Victor M Darley-Usmar , Anton Simeonov , Alex G Waterson , Ajit Jadhav , Matthew D Hall , David J Maloney

Arsenic exposure and increased

Redox Biochemistry and Chemistry

Avec: Dorian M Cheff , Helena Skröder , Evana Akhtar , Qing Cheng , Matthew D Hall , Rubhana Raqib , Maria Kippler , Marie Vahter , Elias S J Arnér

Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities.

Orphanet journal of rare diseases

Avec: Dorian M Cheff , Alysson R Muotri , Brent R Stockwell , Edward E Schmidt , Qitao Ran , Reena V Kartha , Simon C Johnson , Plavi Mittal , Elias S J Arnér , Kristen M Wigby , Matthew D Hall , Sanath Kumar Ramesh

The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1.

Redox biology

Avec: Dorian M Cheff , Chuying Huang , Karoline C Scholzen , Radosveta Gencheva , Michael H Ronzetti , Qing Cheng , Matthew D Hall , Elias S J Arnér

Predictive models for estimating cytotoxicity on the basis of chemical structures.

Bioorganic & medicinal chemistry

Avec: Hongmao Sun , Yuhong Wang , Dorian M Cheff , Matthew D Hall , Min Shen

Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.

SLAS discovery : advancing life sciences R & D

Avec: Olivia W Lee , Shelley Austin , Madison Gamma , Dorian M Cheff , Tobie D Lee , Kelli M Wilson , Joseph Johnson , Jameson Travers , John C Braisted , Rajarshi Guha , Carleen Klumpp-Thomas , Min Shen , Matthew D Hall

Discovery and Optimization of 2

Journal of medicinal chemistry

Avec: Jason M Rohde , Surendra Karavadhi , Rajan Pragani , Li Liu , Yuhong Fang , Weihe Zhang , Andrew McIver , Hongchao Zheng , Qingyang Liu , Mindy I Davis , Daniel J Urban , Tobie D Lee , Dorian M Cheff , Melinda Hollingshead , Mark J Henderson , Natalia J Martinez , Kyle R Brimacombe , Adam Yasgar , Wei Zhao , Carleen Klumpp-Thomas , Sam Michael , Joseph Covey , William J Moore , Gordon M Stott , Zhuyin Li , Anton Simeonov , Ajit Jadhav , Stephen Frye , Matthew D Hall , Min Shen , Xiaodong Wang , Samarjit Patnaik , Matthew B Boxer

Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4.

Redox biology

Avec: Dorian M Cheff , Qing Cheng , Hui Guo , Jameson Travers , Carleen Klumpp-Thomas , Min Shen , Elias S J Arnér , Matthew D Hall

Réseau de co-auteurs

Matthew D Hall 9 collaborations

Tobie D Lee 4 collaborations

Carleen Klumpp-Thomas 4 collaborations

Elias S J Arnér 4 collaborations

Min Shen 4 collaborations

Anton Simeonov 3 collaborations

Qing Cheng 3 collaborations

Sam Michael 2 collaborations

Kelli M Wilson 2 collaborations

Daniel J Urban 2 collaborations

Kyle R Brimacombe 2 collaborations

Mark J Henderson 2 collaborations

Yuhong Fang 2 collaborations

William J Moore 2 collaborations

Gordon M Stott 2 collaborations

Ajit Jadhav 2 collaborations

Jameson Travers 2 collaborations

Jacob S Roth 1 collaboration

Maya L Gosztyla 1 collaboration

Rosita R Asawa 1 collaboration

Carina Danchik 1 collaboration

Ganesha Rai 1 collaboration

Bryan T Mott 1 collaboration

Xin Hu 1 collaboration

Shyh-Ming Yang 1 collaboration

Gloria A Benavides 1 collaboration

Michelle S Johnson 1 collaboration

Giuseppe L Squadrito 1 collaboration

Hu Zhu 1 collaboration

Katherine Pohida 1 collaboration

Gary A Sulikowski 1 collaboration

David M Dranow 1 collaboration

Md Kabir 1 collaboration

Pranav Shah 1 collaboration

Elias Padilha 1 collaboration

Dingyin Tao 1 collaboration

Plamen P Christov 1 collaboration

Kwangho Kim 1 collaboration

Somnath Jana 1 collaboration

Pavan Muttil 1 collaboration

Tamara Anderson 1 collaboration

Nitesh K Kunda 1 collaboration

Helen J Hathaway 1 collaboration

Donna F Kusewitt 1 collaboration

Nobu Oshima 1 collaboration

Murali Cherukuri 1 collaboration

Douglas R Davies 1 collaboration

Jeffrey P Norenberg 1 collaboration

Larry A Sklar 1 collaboration

Chi V Dang 1 collaboration

Leonard Neckers 1 collaboration

Andrew J Flint 1 collaboration

Victor M Darley-Usmar 1 collaboration

Alex G Waterson 1 collaboration

David J Maloney 1 collaboration

Helena Skröder 1 collaboration

Evana Akhtar 1 collaboration

Rubhana Raqib 1 collaboration

Maria Kippler 1 collaboration

Marie Vahter 1 collaboration

Alysson R Muotri 1 collaboration

Brent R Stockwell 1 collaboration

Edward E Schmidt 1 collaboration

Qitao Ran 1 collaboration

Reena V Kartha 1 collaboration

Simon C Johnson 1 collaboration

Plavi Mittal 1 collaboration

Kristen M Wigby 1 collaboration

Sanath Kumar Ramesh 1 collaboration

Chuying Huang 1 collaboration

Karoline C Scholzen 1 collaboration

Radosveta Gencheva 1 collaboration

Michael H Ronzetti 1 collaboration

Hongmao Sun 1 collaboration

Yuhong Wang 1 collaboration

Olivia W Lee 1 collaboration

Shelley Austin 1 collaboration

Madison Gamma 1 collaboration

Joseph Johnson 1 collaboration

John C Braisted 1 collaboration

Rajarshi Guha 1 collaboration

Jason M Rohde 1 collaboration

Surendra Karavadhi 1 collaboration

Rajan Pragani 1 collaboration

Li Liu 1 collaboration

Weihe Zhang 1 collaboration

Andrew McIver 1 collaboration

Hongchao Zheng 1 collaboration

Qingyang Liu 1 collaboration

Mindy I Davis 1 collaboration

Melinda Hollingshead 1 collaboration

Natalia J Martinez 1 collaboration

Adam Yasgar 1 collaboration

Wei Zhao 1 collaboration

Joseph Covey 1 collaboration

Zhuyin Li 1 collaboration

Stephen Frye 1 collaboration

Xiaodong Wang 1 collaboration

Samarjit Patnaik 1 collaboration

Matthew B Boxer 1 collaboration

Hui Guo 1 collaboration