Elena Ceccacci

Affiliations

Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan, Italy.

Publications (9)

Co-targeting leukemia-initiating cells and leukemia bulk leads to disease eradication.

Leukemia

Avec: Simona Moretti , Amal Kamal Abdel-Aziz , Elena Ceccacci , Isabella Pallavicini , Fabio Santoro , Hugues de Thé , Saverio Minucci

LSD1-directed therapy affects glioblastoma tumorigenicity by deregulating the protective ATF4-dependent integrated stress response.

Science translational medicine

Avec: Stefania Faletti , Daniela Osti , Elena Ceccacci , Cristina Richichi , Brunella Costanza , Luciano Nicosia , Roberta Noberini , Giulia Marotta , Laura Furia , Mario R Faretta , Silvia Brambillasca , Micaela Quarto , Luca Bertero , Renzo Boldorini , Bianca Pollo , Sara Gandini , Davide Cora , Saverio Minucci , Ciro Mercurio , Mario Varasi , Tiziana Bonaldi , Giuliana Pelicci

Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML.

Oncogene

Avec: Luciano Nicosia , Francesca Ludovica Boffo , Elena Ceccacci , Fabio Conforti , Isabella Pallavicini , Fabio Bedin , Roberto Ravasio , Enrico Massignani , Tim C P Somervaille , Saverio Minucci , Tiziana Bonaldi

A Refined Single Cell Landscape of Haematopoiesis in the Mouse Foetal Liver.

Journal of developmental biology

Avec: Elena Ceccacci , Emanuela Villa , Fabio Santoro , Saverio Minucci , Christiana Ruhrberg , Alessandro Fantin

Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation.

Science advances

Avec: Roberto Ravasio , Elena Ceccacci , Luciano Nicosia , Amir Hosseini , Pier Luigi Rossi , Iros Barozzi , Lorenzo Fornasari , Roberto Dal Zuffo , Sergio Valente , Rossella Fioravanti , Ciro Mercurio , Mario Varasi , Andrea Mattevi , Antonello Mai , Giulio Pavesi , Tiziana Bonaldi , Saverio Minucci

Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition.

Haematologica

Avec: Amal Kamal Abdel-Aziz , Isabella Pallavicini , Elena Ceccacci , Giuseppe Meroni , Mona Kamal Saadeldin , Mario Varasi , Saverio Minucci

KIT Is Required for Fetal Liver Hematopoiesis.

Frontiers in cell and developmental biology

Avec: Alessandro Fantin , Carlotta Tacconi , Emanuela Villa , Elena Ceccacci , Laura Denti , Christiana Ruhrberg

CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer.

Nature communications

Avec: M G Filippone , D Gaglio , R Bonfanti , F A Tucci , E Ceccacci , R Pennisi , M Bonanomi , G Jodice , M Tillhon , F Montani , G Bertalot , S Freddi , M Vecchi , A Taglialatela , M Romanenghi , F Romeo , N Bianco , E Munzone , F Sanguedolce , G Vago , G Viale , P P Di Fiore , S Minucci , L Alberghina , M Colleoni , P Veronesi , D Tosoni , S Pece

LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8

Nature communications

Avec: Isabella Pallavicini , Teresa Maria Frasconi , Carlotta Catozzi , Elena Ceccacci , Silvia Tiberti , Dorothee Haas , Jule Samson , Christoph Heuser-Loy , Carina B Nava Lauson , Marta Mangione , Elisa Preto , Alberto Bigogno , Eleonora Sala , Matteo Iannacone , Ciro Mercurio , Luca Gattinoni , Ignazio Caruana , Mirela Kuka , Luigi Nezi , Saverio Minucci , Teresa Manzo

Réseau de co-auteurs

Saverio Minucci 7 collaborations

Isabella Pallavicini 4 collaborations

Luciano Nicosia 3 collaborations

Ciro Mercurio 3 collaborations

Mario Varasi 3 collaborations

Tiziana Bonaldi 3 collaborations

Amal Kamal Abdel-Aziz 2 collaborations

Fabio Santoro 2 collaborations

Roberto Ravasio 2 collaborations

Emanuela Villa 2 collaborations

Christiana Ruhrberg 2 collaborations

Alessandro Fantin 2 collaborations

Simona Moretti 1 collaboration

Hugues de Thé 1 collaboration

Stefania Faletti 1 collaboration

Daniela Osti 1 collaboration

Cristina Richichi 1 collaboration

Brunella Costanza 1 collaboration

Roberta Noberini 1 collaboration

Giulia Marotta 1 collaboration

Laura Furia 1 collaboration

Mario R Faretta 1 collaboration

Silvia Brambillasca 1 collaboration

Micaela Quarto 1 collaboration

Luca Bertero 1 collaboration

Renzo Boldorini 1 collaboration

Bianca Pollo 1 collaboration

Sara Gandini 1 collaboration

Davide Cora 1 collaboration

Giuliana Pelicci 1 collaboration

Francesca Ludovica Boffo 1 collaboration

Fabio Conforti 1 collaboration

Fabio Bedin 1 collaboration

Enrico Massignani 1 collaboration

Tim C P Somervaille 1 collaboration

Amir Hosseini 1 collaboration

Pier Luigi Rossi 1 collaboration

Iros Barozzi 1 collaboration

Lorenzo Fornasari 1 collaboration

Roberto Dal Zuffo 1 collaboration

Sergio Valente 1 collaboration

Rossella Fioravanti 1 collaboration

Andrea Mattevi 1 collaboration

Antonello Mai 1 collaboration

Giulio Pavesi 1 collaboration

Giuseppe Meroni 1 collaboration

Mona Kamal Saadeldin 1 collaboration

Carlotta Tacconi 1 collaboration

Laura Denti 1 collaboration

M G Filippone 1 collaboration

D Gaglio 1 collaboration

R Bonfanti 1 collaboration

F A Tucci 1 collaboration

E Ceccacci 1 collaboration

R Pennisi 1 collaboration

M Bonanomi 1 collaboration

G Jodice 1 collaboration

M Tillhon 1 collaboration

F Montani 1 collaboration

G Bertalot 1 collaboration

S Freddi 1 collaboration

M Vecchi 1 collaboration

A Taglialatela 1 collaboration

M Romanenghi 1 collaboration

F Romeo 1 collaboration

N Bianco 1 collaboration

E Munzone 1 collaboration

F Sanguedolce 1 collaboration

G Vago 1 collaboration

G Viale 1 collaboration

P P Di Fiore 1 collaboration

S Minucci 1 collaboration

L Alberghina 1 collaboration

M Colleoni 1 collaboration

P Veronesi 1 collaboration

D Tosoni 1 collaboration

S Pece 1 collaboration

Teresa Maria Frasconi 1 collaboration

Carlotta Catozzi 1 collaboration

Silvia Tiberti 1 collaboration

Dorothee Haas 1 collaboration

Jule Samson 1 collaboration

Christoph Heuser-Loy 1 collaboration

Carina B Nava Lauson 1 collaboration

Marta Mangione 1 collaboration

Elisa Preto 1 collaboration

Alberto Bigogno 1 collaboration

Eleonora Sala 1 collaboration

Matteo Iannacone 1 collaboration

Luca Gattinoni 1 collaboration

Ignazio Caruana 1 collaboration

Mirela Kuka 1 collaboration

Luigi Nezi 1 collaboration

Teresa Manzo 1 collaboration