Elizabeth Pohler

Affiliations

Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.

Publications (8)

Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses.

eLife

Avec: Stephan Wilmes , Polly-Anne Jeffrey , Jonathan Martinez-Fabregas , Maximillian Hafer , Paul K Fyfe , Elizabeth Pohler , Silvia Gaggero , Martín López-García , Grant Lythe , Charles Taylor , Thomas Guerrier , David Launay , Suman Mitra , Jacob Piehler , Carmen Molina-París , Ignacio Moraga

Identifying cytokine signaling signatures in primary human Th-1 cells by phospho-proteomics analysis.

STAR protocols

Avec: Jonathan Martinez-Fabregas , Elizabeth Pohler , Ignacio Moraga

Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses.

Science signaling

Avec: Claire Gorby , Junel Sotolongo Bellón , Stephan Wilmes , Walid Warda , Elizabeth Pohler , Paul K Fyfe , Adeline Cozzani , Christophe Ferrand , Mark R Walter , Suman Mitra , Jacob Piehler , Ignacio Moraga

Molecular and cellular factors determining the functional pleiotropy of cytokines.

The FEBS journal

Avec: Alison McFarlane , Elizabeth Pohler , Ignacio Moraga

CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci.

Cell reports

Avec: Jonathan Martinez-Fabregas , Luopin Wang , Elizabeth Pohler , Adeline Cozzani , Stephan Wilmes , Majid Kazemian , Suman Mitra , Ignacio Moraga

Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency.

Nature communications

Avec: Scott Gardner , Yibo Jin , Paul K Fyfe , Tomas B Voisin , Junel Sotolongo Bellón , Elizabeth Pohler , Jacob Piehler , Ignacio Moraga , Doryen Bubeck

Kinetics of cytokine receptor trafficking determine signaling and functional selectivity.

eLife

Avec: Jonathan Martinez-Fabregas , Stephan Wilmes , Luopin Wang , Maximillian Hafer , Elizabeth Pohler , Juliane Lokau , Christoph Garbers , Adeline Cozzani , Paul K Fyfe , Jacob Piehler , Majid Kazemian , Suman Mitra , Ignacio Moraga

IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.

Science immunology

Avec: Silvia Gaggero , Jonathan Martinez-Fabregas , Adeline Cozzani , Paul K Fyfe , Malo Leprohon , Jie Yang , F Emil Thomasen , Hauke Winkelmann , Romain Magnez , Alberto G Conti , Stephan Wilmes , Elizabeth Pohler , Manuel van Gijsel Bonnello , Xavier Thuru , Bruno Quesnel , Fabrice Soncin , Jacob Piehler , Kresten Lindorff-Larsen , Rahul Roychoudhuri , Ignacio Moraga , Suman Mitra

Réseau de co-auteurs

Ignacio Moraga 8 collaborations

Stephan Wilmes 5 collaborations

Jonathan Martinez-Fabregas 5 collaborations

Paul K Fyfe 5 collaborations

Suman Mitra 5 collaborations

Jacob Piehler 5 collaborations

Adeline Cozzani 4 collaborations

Maximillian Hafer 2 collaborations

Silvia Gaggero 2 collaborations

Junel Sotolongo Bellón 2 collaborations

Luopin Wang 2 collaborations

Majid Kazemian 2 collaborations

Polly-Anne Jeffrey 1 collaboration

Martín López-García 1 collaboration

Grant Lythe 1 collaboration

Charles Taylor 1 collaboration

Thomas Guerrier 1 collaboration

David Launay 1 collaboration

Carmen Molina-París 1 collaboration

Claire Gorby 1 collaboration

Walid Warda 1 collaboration

Christophe Ferrand 1 collaboration

Mark R Walter 1 collaboration

Alison McFarlane 1 collaboration

Scott Gardner 1 collaboration

Yibo Jin 1 collaboration

Tomas B Voisin 1 collaboration

Doryen Bubeck 1 collaboration

Juliane Lokau 1 collaboration

Christoph Garbers 1 collaboration

Malo Leprohon 1 collaboration

Jie Yang 1 collaboration

F Emil Thomasen 1 collaboration

Hauke Winkelmann 1 collaboration

Romain Magnez 1 collaboration

Alberto G Conti 1 collaboration

Manuel van Gijsel Bonnello 1 collaboration

Xavier Thuru 1 collaboration

Bruno Quesnel 1 collaboration

Fabrice Soncin 1 collaboration

Kresten Lindorff-Larsen 1 collaboration

Rahul Roychoudhuri 1 collaboration