Florence Vallelian

Affiliations

Division of Internal Medicine, University Hospital of Zurich, Zurich, Switzerland.

Publications (23)

Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.

The Journal of clinical investigation

Avec: Michael Hugelshofer , Raphael M Buzzi , Christian A Schaer , Henning Richter , Kevin Akeret , Vania Anagnostakou , Leila Mahmoudi , Raphael Vaccani , Florence Vallelian , Jeremy W Deuel , Peter W Kronen , Zsolt Kulcsar , Luca Regli , Jin Hyen Baek , Ivan S Pires , Andre F Palmer , Matthias Dennler , Rok Humar , Paul W Buehler , Patrick R Kircher , Emanuela Keller , Dominik J Schaer

Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia.

Cell death and differentiation

Avec: Florence Vallelian , Raphael M Buzzi , Marc Pfefferlé , Ayla Yalamanoglu , Irina L Dubach , Andreas Wassmer , Thomas Gentinetta , Kerstin Hansen , Rok Humar , Nadja Schulthess , Christian A Schaer , Dominik J Schaer

Acute Hemolysis and Heme Suppress Anti-CD40 Antibody-Induced Necro-Inflammatory Liver Disease.

Frontiers in immunology

Avec: Marc Pfefferlé , Giada Ingoglia , Christian A Schaer , Kerstin Hansen , Nadja Schulthess , Rok Humar , Dominik J Schaer , Florence Vallelian

[Light and Shadow of Hyperuricemia - Neuroprotection, Comorbidities and Therapeutic Strategies].

Praxis

Avec: Heiko Pohl , Florence Vallelian , Gregor Herfs

Alternate day versus consecutive day oral iron supplementation in iron-depleted women: a randomized double-blind placebo-controlled study.

EClinicalMedicine

Avec: Hanna K von Siebenthal , Sara Gessler , Florence Vallelian , Joachim Steinwendner , Urs-Martin Kuenzi , Diego Moretti , Michael B Zimmermann , Nicole U Stoffel

Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function.

Advances in experimental medicine and biology

Avec: Marc Pfefferlé , Florence Vallelian

Cerebrospinal fluid hemoglobin drives subarachnoid hemorrhage-related secondary brain injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Avec: Kevin Akeret , Raphael M Buzzi , Christian A Schaer , Bart R Thomson , Florence Vallelian , Sophie Wang , Jan Willms , Martina Sebök , Ulrike Held , Jeremy W Deuel , Rok Humar , Luca Regli , Emanuela Keller , Michael Hugelshofer , Dominik J Schaer

Spatial transcriptome analysis defines heme as a hemopexin-targetable inflammatoxin in the brain.

Free radical biology & medicine

Avec: Raphael M Buzzi , Kevin Akeret , Nina Schwendinger , Jan Klohs , Florence Vallelian , Michael Hugelshofer , Dominik J Schaer

Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease.

Free radical biology & medicine

Avec: Paul W Buehler , Delaney Swindle , David I Pak , Scott K Ferguson , Susan M Majka , Vijaya Karoor , Radu Moldovan , Chantal Sintas , Jennifer Black , Thomas Gentinetta , Raphael M Buzzi , Florence Vallelian , Andreas Wassmer , Monika Edler , Joseph Bain , Daniel Schu , Kathryn Hassell , Rachelle Nuss , Dominik J Schaer , David C Irwin

Impaired health-related quality of life in long-COVID syndrome after mild to moderate COVID-19.

Scientific reports

Avec: Stefan Malesevic , Noriane A Sievi , Patrick Baumgartner , Katharina Roser , Grit Sommer , Dörthe Schmidt , Florence Vallelian , Ilijas Jelcic , Christian F Clarenbach , Malcolm Kohler

Agonistic Anti-CD40 Antibody Triggers an Acute Liver Crisis With Systemic Inflammation in Humanized Sickle Cell Disease Mice.

Frontiers in immunology

Avec: Ayla Yalamanoglu , Irina L Dubach , Nadja Schulthess , Giada Ingoglia , Delaney C Swindle , Rok Humar , Dominik J Schaer , Paul W Buehler , David C Irwin , Florence Vallelian

Modular Platform for the Development of Recombinant Hemoglobin Scavenger Biotherapeutics.

Molecular pharmaceutics

Avec: Raphael M Buzzi , Catherine M Owczarek , Kevin Akeret , Andrea Tester , Natasha Pereira , Rebecca Butcher , Valérie Brügger-Verdon , Matthew P Hardy , Marlies Illi , Andreas Wassmer , Florence Vallelian , Rok Humar , Michael Hugelshofer , Paul W Buehler , Thomas Gentinetta , Dominik J Schaer

Erythrophagocytes in hemolytic anemia, wound healing, and cancer.

Trends in molecular medicine

Avec: Rok Humar , Dominik J Schaer , Florence Vallelian

Chest CT Findings after Mild COVID-19 Do Not Explain Persisting Respiratory Symptoms: An Explanatory Study.

Diagnostics (Basel, Switzerland)

Avec: Stefan Malesevic , Noriane A Sievi , Jonas Herth , Felix Schmidt , Dörthe Schmidt , Florence Vallelian , Ilijas Jelcic , Lisa Jungblut , Thomas Frauenfelder , Malcolm Kohler , Katharina Martini , Christian F Clarenbach

Hemorrhage-activated NRF2 in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance.

The Journal of clinical investigation

Avec: Dominik J Schaer , Nadja Schulthess-Lutz , Livio Baselgia , Kerstin Hansen , Raphael M Buzzi , Rok Humar , Elena Dürst , Florence Vallelian

Line-selective macrophage activation with an anti-CD40 antibody drives a hemophagocytic syndrome in mice.

Blood advances

Avec: Giada Ingoglia , Ayla Yalamanoglu , Marc Pfefferlé , Irina L Dubach , Christian A Schaer , Kristyna Valkova , Kerstin Hansen , Nadja Schulthess , Rok Humar , Dominik J Schaer , Florence Vallelian

Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes.

The Journal of clinical investigation

Avec: Marc Pfefferlé , Giada Ingoglia , Christian A Schaer , Ayla Yalamanoglu , Raphael Buzzi , Irina L Dubach , Ge Tan , Emilio Y López-Cano , Nadja Schulthess , Kerstin Hansen , Rok Humar , Dominik J Schaer , Florence Vallelian

Clinical outcomes in patients with systemic lupus erythematosus treated with belimumab in clinical practice settings: a retrospective analysis of results from the OBSErve study in Switzerland.

Swiss medical weekly

Avec: Johannes von Kempis , Sabine Duetsch , Nicola Reuschling , Rahel Villiger , Peter M Villiger , Florence Vallelian , Dominik J Schaer , Ruediger B Mueller

The effect of a natural polyphenol supplement on iron absorption in adults with hereditary hemochromatosis.

European journal of nutrition

Avec: Simone Buerkli , Laura Salvioni , Natalie Koller , Christophe Zeder , Maria José Teles , Graça Porto , Jana Helena Habermann , Irina Léa Dubach , Florence Vallelian , Beat M Frey , Diego Moretti , Jeannine Baumgartner , Michael B Zimmermann

Hemolysis, free hemoglobin toxicity, and scavenger protein therapeutics.

Blood

Avec: Florence Vallelian , Paul W Buehler , Dominik J Schaer

Physical Health-Related Quality of Life Improves over Time in Post-COVID-19 Patients: An Exploratory Prospective Study.

Journal of clinical medicine

Avec: Stefan Malesevic , Noriane A Sievi , Dörthe Schmidt , Florence Vallelian , Ilijas Jelcic , Malcolm Kohler , Christian F Clarenbach

MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage.

Journal of neuroinflammation

Avec: Kevin Akeret , Raphael M Buzzi , Bart R Thomson , Nina Schwendinger , Jan Klohs , Nadja Schulthess-Lutz , Livio Baselgia , Kerstin Hansen , Luca Regli , Florence Vallelian , Michael Hugelshofer , Dominik J Schaer

Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity.

Journal for immunotherapy of cancer

Avec: Marc Pfefferlé , Irina L Dubach , Raphael M Buzzi , Elena Dürst , Nadja Schulthess-Lutz , Livio Baselgia , Kerstin Hansen , Larissa Imhof , Sandra Koernig , Didier Le Roy , Thierry Roger , Rok Humar , Dominik J Schaer , Florence Vallelian

Réseau de co-auteurs

Dominik J Schaer 16 collaborations

Rok Humar 11 collaborations

Raphael M Buzzi 9 collaborations

Kerstin Hansen 7 collaborations

Christian A Schaer 6 collaborations

Marc Pfefferlé 6 collaborations

Michael Hugelshofer 5 collaborations

Kevin Akeret 5 collaborations

Paul W Buehler 5 collaborations

Irina L Dubach 5 collaborations

Nadja Schulthess 5 collaborations

Ayla Yalamanoglu 4 collaborations

Giada Ingoglia 4 collaborations

Luca Regli 3 collaborations

Andreas Wassmer 3 collaborations

Thomas Gentinetta 3 collaborations

Stefan Malesevic 3 collaborations

Noriane A Sievi 3 collaborations

Dörthe Schmidt 3 collaborations

Ilijas Jelcic 3 collaborations

Christian F Clarenbach 3 collaborations

Malcolm Kohler 3 collaborations

Nadja Schulthess-Lutz 3 collaborations

Livio Baselgia 3 collaborations

Jeremy W Deuel 2 collaborations

Emanuela Keller 2 collaborations

Diego Moretti 2 collaborations

Michael B Zimmermann 2 collaborations

Bart R Thomson 2 collaborations

Nina Schwendinger 2 collaborations

Jan Klohs 2 collaborations

David C Irwin 2 collaborations

Elena Dürst 2 collaborations

Henning Richter 1 collaboration

Vania Anagnostakou 1 collaboration

Leila Mahmoudi 1 collaboration

Raphael Vaccani 1 collaboration

Peter W Kronen 1 collaboration

Zsolt Kulcsar 1 collaboration

Jin Hyen Baek 1 collaboration

Ivan S Pires 1 collaboration

Andre F Palmer 1 collaboration

Matthias Dennler 1 collaboration

Patrick R Kircher 1 collaboration

Heiko Pohl 1 collaboration

Gregor Herfs 1 collaboration

Hanna K von Siebenthal 1 collaboration

Sara Gessler 1 collaboration

Joachim Steinwendner 1 collaboration

Urs-Martin Kuenzi 1 collaboration

Nicole U Stoffel 1 collaboration

Sophie Wang 1 collaboration

Jan Willms 1 collaboration

Martina Sebök 1 collaboration

Ulrike Held 1 collaboration

Delaney Swindle 1 collaboration

David I Pak 1 collaboration

Scott K Ferguson 1 collaboration

Susan M Majka 1 collaboration

Vijaya Karoor 1 collaboration

Radu Moldovan 1 collaboration

Chantal Sintas 1 collaboration

Jennifer Black 1 collaboration

Monika Edler 1 collaboration

Joseph Bain 1 collaboration

Daniel Schu 1 collaboration

Kathryn Hassell 1 collaboration

Rachelle Nuss 1 collaboration

Patrick Baumgartner 1 collaboration

Katharina Roser 1 collaboration

Grit Sommer 1 collaboration

Delaney C Swindle 1 collaboration

Catherine M Owczarek 1 collaboration

Andrea Tester 1 collaboration

Natasha Pereira 1 collaboration

Rebecca Butcher 1 collaboration

Valérie Brügger-Verdon 1 collaboration

Matthew P Hardy 1 collaboration

Marlies Illi 1 collaboration

Jonas Herth 1 collaboration

Felix Schmidt 1 collaboration

Lisa Jungblut 1 collaboration

Thomas Frauenfelder 1 collaboration

Katharina Martini 1 collaboration

Kristyna Valkova 1 collaboration

Raphael Buzzi 1 collaboration

Ge Tan 1 collaboration

Emilio Y López-Cano 1 collaboration

Johannes von Kempis 1 collaboration

Sabine Duetsch 1 collaboration

Nicola Reuschling 1 collaboration

Rahel Villiger 1 collaboration

Peter M Villiger 1 collaboration

Ruediger B Mueller 1 collaboration

Simone Buerkli 1 collaboration

Laura Salvioni 1 collaboration

Natalie Koller 1 collaboration

Christophe Zeder 1 collaboration

Maria José Teles 1 collaboration

Graça Porto 1 collaboration

Jana Helena Habermann 1 collaboration

Irina Léa Dubach 1 collaboration

Beat M Frey 1 collaboration

Jeannine Baumgartner 1 collaboration

Larissa Imhof 1 collaboration

Sandra Koernig 1 collaboration

Didier Le Roy 1 collaboration

Thierry Roger 1 collaboration