Françoise Debart

Affiliations

IBMM, UMR 5247 CNRS, Université de Montpellier, ENSCM, Montpellier, France.

Publications (19)

The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation.

Journal of virology

Avec: Coralie Valle , Baptiste Martin , Françoise Debart , Jean-Jacques Vasseur , Isabelle Imbert , Bruno Canard , Bruno Coutard , Etienne Decroly

Combining Chemical Synthesis and Enzymatic Methylation to Access Short RNAs with Various 5' Caps.

Chembiochem : a European journal of chemical biology

Avec: Nils Muthmann , Théo Guez , Jean-Jacques Vasseur , Samie R Jaffrey , Françoise Debart , Andrea Rentmeister

The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation.

PLoS pathogens

Avec: Priscila Sutto-Ortiz , Sergey Tcherniuk , Nina Ysebaert , Pravien Abeywickrema , Mathieu Noël , Alice Decombe , Françoise Debart , Jean-Jacques Vasseur , Bruno Canard , Dirk Roymans , Peter Rigaux , Jean-François Eléouët , Etienne Decroly

AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5.

Antiviral research

Avec: Mikael Feracci , Cécilia Eydoux , Véronique Fattorini , Lea Lo Bello , Pierre Gauffre , Barbara Selisko , Priscila Sutto-Ortiz , Ashleigh Shannon , Hongjie Xia , Pei-Yong Shi , Mathieu Noel , Françoise Debart , Jean-Jacques Vasseur , Steve Good , Kai Lin , Adel Moussa , Jean-Pierre Sommadossi , Aurélie Chazot , Karine Alvarez , Jean-Claude Guillemot , Etienne Decroly , François Ferron , Bruno Canard

FTO-mediated cytoplasmic m

Nature communications

Avec: Sébastien Relier , Julie Ripoll , Hélène Guillorit , Amandine Amalric , Cyrinne Achour , Florence Boissière , Jérôme Vialaret , Aurore Attina , Françoise Debart , Armelle Choquet , Françoise Macari , Virginie Marchand , Yuri Motorin , Emmanuelle Samalin , Jean-Jacques Vasseur , Julie Pannequin , Francesca Aguilo , Evelyne Lopez-Crapez , Christophe Hirtz , Eric Rivals , Amandine Bastide , Alexandre David

Identification of the m

Molecular cell

Avec: Konstantinos Boulias , Diana Toczydłowska-Socha , Ben R Hawley , Noa Liberman , Ken Takashima , Sara Zaccara , Théo Guez , Jean-Jacques Vasseur , Françoise Debart , L Aravind , Samie R Jaffrey , Eric Lieberman Greer

Potent Inhibition of SARS-CoV-2 nsp14

Journal of medicinal chemistry

Avec: Rostom Ahmed-Belkacem , Marcel Hausdorff , Adrien Delpal , Priscila Sutto-Ortiz , Agathe M G Colmant , Franck Touret , Natacha S Ogando , Eric J Snijder , Bruno Canard , Bruno Coutard , Jean-Jacques Vasseur , Etienne Decroly , Françoise Debart

Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases.

European journal of medicinal chemistry

Avec: Marcel Hausdorff , Adrien Delpal , Sarah Barelier , Laura Nicollet , Bruno Canard , Franck Touret , Agathe Colmant , Bruno Coutard , Jean-Jacques Vasseur , Etienne Decroly , Françoise Debart

FTO controls reversible m

Nature chemical biology

Avec: Jan Mauer , Miriam Sindelar , Vladimir Despic , Théo Guez , Ben R Hawley , Jean-Jacques Vasseur , Andrea Rentmeister , Steven S Gross , Livio Pellizzoni , Françoise Debart , Hani Goodarzi , Samie R Jaffrey

First insights into the structural features of Ebola virus methyltransferase activities.

Nucleic acids research

Avec: Coralie Valle , Baptiste Martin , François Ferron , Véronique Roig-Zamboni , Aline Desmyter , Françoise Debart , Jean-Jacques Vasseur , Bruno Canard , Bruno Coutard , Etienne Decroly

A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome.

Nucleic acids research

Avec: Ashleigh Shannon , Bhawna Sama , Pierre Gauffre , Théo Guez , Françoise Debart , Jean-Jacques Vasseur , Etienne Decroly , Bruno Canard , François Ferron

Internal RNA 2'O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect.

Nucleic acids research

Avec: Priscila El Kazzi , Nadia Rabah , Célia Chamontin , Lina Poulain , François Ferron , Françoise Debart , Bruno Canard , Dorothée Missé , Bruno Coutard , Sébastien Nisole , Etienne Decroly

Access to High-Purity

Chembiochem : a European journal of chemical biology

Avec: Mathieu Noël , Theo Guez , Yann Thillier , Jean-Jacques Vasseur , Françoise Debart

Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase.

European journal of medicinal chemistry

Avec: Rostom Ahmed-Belkacem , Priscila Sutto-Ortiz , Mathis Guiraud , Bruno Canard , Jean-Jacques Vasseur , Etienne Decroly , Françoise Debart

Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers.

Molecules (Basel, Switzerland)

Avec: Florian Gauthier , Jean-Rémi Bertrand , Jean-Jacques Vasseur , Christelle Dupouy , Françoise Debart

Importance of RNA length for in vitro encapsidation by the nucleoprotein of human respiratory syncytial virus.

The Journal of biological chemistry

Avec: Lorène Gonnin , Charles-Adrien Richard , Irina Gutsche , Didier Chevret , Joris Troussier , Jean-Jacques Vasseur , Françoise Debart , Jean-François Eléouët , Marie Galloux

5'-cap RNA/SAM mimetic conjugates as bisubstrate inhibitors of viral RNA cap 2'-O-methyltransferases.

Bioorganic chemistry

Avec: Rostom Ahmed-Belkacem , Priscila Sutto-Ortiz , Adrien Delpal , Joris Troussier , Bruno Canard , Jean-Jacques Vasseur , Etienne Decroly , Françoise Debart

RSC medicinal chemistry

Avec: Rostom Ahmed-Belkacem , Joris Troussier , Adrien Delpal , Bruno Canard , Jean-Jacques Vasseur , Etienne Decroly , Françoise Debart

Accelerated, high-quality photolithographic synthesis of RNA microarrays in situ.

Science advances

Avec: Tadija Kekić , Nemanja Milisavljević , Joris Troussier , Amina Tahir , Françoise Debart , Jory Lietard

Réseau de co-auteurs

Jean-Jacques Vasseur 17 collaborations

Bruno Canard 11 collaborations

Etienne Decroly 11 collaborations

Bruno Coutard 5 collaborations

Priscila Sutto-Ortiz 5 collaborations

Théo Guez 4 collaborations

François Ferron 4 collaborations

Rostom Ahmed-Belkacem 4 collaborations

Adrien Delpal 4 collaborations

Joris Troussier 4 collaborations

Samie R Jaffrey 3 collaborations

Coralie Valle 2 collaborations

Baptiste Martin 2 collaborations

Andrea Rentmeister 2 collaborations

Mathieu Noël 2 collaborations

Jean-François Eléouët 2 collaborations

Pierre Gauffre 2 collaborations

Ashleigh Shannon 2 collaborations

Ben R Hawley 2 collaborations

Marcel Hausdorff 2 collaborations

Franck Touret 2 collaborations

Isabelle Imbert 1 collaboration

Nils Muthmann 1 collaboration

Sergey Tcherniuk 1 collaboration

Nina Ysebaert 1 collaboration

Pravien Abeywickrema 1 collaboration

Alice Decombe 1 collaboration

Dirk Roymans 1 collaboration

Peter Rigaux 1 collaboration

Mikael Feracci 1 collaboration

Cécilia Eydoux 1 collaboration

Véronique Fattorini 1 collaboration

Lea Lo Bello 1 collaboration

Barbara Selisko 1 collaboration

Hongjie Xia 1 collaboration

Pei-Yong Shi 1 collaboration

Mathieu Noel 1 collaboration

Steve Good 1 collaboration

Kai Lin 1 collaboration

Adel Moussa 1 collaboration

Jean-Pierre Sommadossi 1 collaboration

Aurélie Chazot 1 collaboration

Karine Alvarez 1 collaboration

Jean-Claude Guillemot 1 collaboration

Sébastien Relier 1 collaboration

Julie Ripoll 1 collaboration

Hélène Guillorit 1 collaboration

Amandine Amalric 1 collaboration

Cyrinne Achour 1 collaboration

Florence Boissière 1 collaboration

Jérôme Vialaret 1 collaboration

Aurore Attina 1 collaboration

Armelle Choquet 1 collaboration

Françoise Macari 1 collaboration

Virginie Marchand 1 collaboration

Yuri Motorin 1 collaboration

Emmanuelle Samalin 1 collaboration

Julie Pannequin 1 collaboration

Francesca Aguilo 1 collaboration

Evelyne Lopez-Crapez 1 collaboration

Christophe Hirtz 1 collaboration

Eric Rivals 1 collaboration

Amandine Bastide 1 collaboration

Alexandre David 1 collaboration

Konstantinos Boulias 1 collaboration

Diana Toczydłowska-Socha 1 collaboration

Noa Liberman 1 collaboration

Ken Takashima 1 collaboration

Sara Zaccara 1 collaboration

L Aravind 1 collaboration

Eric Lieberman Greer 1 collaboration

Agathe M G Colmant 1 collaboration

Natacha S Ogando 1 collaboration

Eric J Snijder 1 collaboration

Sarah Barelier 1 collaboration

Laura Nicollet 1 collaboration

Agathe Colmant 1 collaboration

Jan Mauer 1 collaboration

Miriam Sindelar 1 collaboration

Vladimir Despic 1 collaboration

Steven S Gross 1 collaboration

Livio Pellizzoni 1 collaboration

Hani Goodarzi 1 collaboration

Véronique Roig-Zamboni 1 collaboration

Aline Desmyter 1 collaboration

Bhawna Sama 1 collaboration

Priscila El Kazzi 1 collaboration

Nadia Rabah 1 collaboration

Célia Chamontin 1 collaboration

Lina Poulain 1 collaboration

Dorothée Missé 1 collaboration

Sébastien Nisole 1 collaboration

Theo Guez 1 collaboration

Yann Thillier 1 collaboration

Mathis Guiraud 1 collaboration

Florian Gauthier 1 collaboration

Jean-Rémi Bertrand 1 collaboration

Christelle Dupouy 1 collaboration

Lorène Gonnin 1 collaboration

Charles-Adrien Richard 1 collaboration

Irina Gutsche 1 collaboration

Didier Chevret 1 collaboration

Marie Galloux 1 collaboration

Tadija Kekić 1 collaboration

Nemanja Milisavljević 1 collaboration

Amina Tahir 1 collaboration

Jory Lietard 1 collaboration