Francesca Cicchetti

Affiliations

Axe Neurosciences du Centre de recherche du CHU de Québec-Université Laval et Département de psychiatrie et de neurosciences de l'Université Laval, Québec, Canada.

Publications (23)

Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases.

The Journal of experimental medicine

Avec: Benoit Mailhot , Marine Christin , Nicolas Tessandier , Chaudy Sotoudeh , Floriane Bretheau , Roxanne Turmel , Ève Pellerin , Feng Wang , Cyril Bories , Charles Joly-Beauparlant , Yves De Koninck , Arnaud Droit , Francesca Cicchetti , Grégory Scherrer , Eric Boilard , Reza Sharif-Naeini , Steve Lacroix

Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease.

Neurobiology of disease

Avec: Stefan Bartl , Abid Oueslati , Amber L Southwell , Alberto Siddu , Michela Parth , Linda Suzanne David , Alexander Maxan , Nina Salhat , Markus Burkert , Andreas Mairhofer , Theresa Friedrich , Halyna Pankevych , Katja Balazs , Guenther Staffler , Michael R Hayden , Francesca Cicchetti , Oskar W Smrzka

A novel wireless brain stimulation device for long-term use in freely moving mice.

Scientific reports

Avec: Melanie Alpaugh , Martine Saint-Pierre , Marilyn Dubois , Benoit Aubé , Dany Arsenault , Jasna Kriz , Antonio Cicchetti , Francesca Cicchetti

Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders.

Molecular psychiatry

Avec: Aurélie de Rus Jacquet , Hélèna L Denis , Francesca Cicchetti , Melanie Alpaugh

Romidepsin (FK228) fails in counteracting the transformed phenotype of rhabdomyosarcoma cells but efficiently radiosensitizes, in vitro and in vivo, the alveolar phenotype subtype.

International journal of radiation biology

Avec: Alessandra Rossetti , Francesco Petragnano , Luisa Milazzo , Francesca Vulcano , Giampiero Macioce , Silvia Codenotti , Matteo Cassandri , Silvia Pomella , Francesca Cicchetti , Irene Fasciani , Cristina Antinozzi , Luigi Di Luigi , Claudio Festuccia , Francesca De Felice , Massimo Vergine , Alessandro Fanzani , Rossella Rota , Roberto Maggio , Antonella Polimeni , Vincenzo Tombolini , Giovanni Luca Gravina , Francesco Marampon

The toxin MPTP generates similar cognitive and locomotor deficits in hTau and tau knock-out mice.

Brain research

Avec: Maud Gratuze , Nicolas Josset , Franck R Petry , Mathieu Pflieger , Laura Eyoum Jong , Geoffrey Truchetti , Isabelle Poitras , Jacinthe Julien , François Bezeau , Françoise Morin , Pershia Samadi , Francesca Cicchetti , Frédéric Bretzner , Emmanuel Planel

Are immunotherapies for Huntington's disease a realistic option?

Molecular psychiatry

Avec: Hélèna L Denis , Florian Lauruol , Francesca Cicchetti

Platelet abnormalities in Huntington's disease.

Journal of neurology, neurosurgery, and psychiatry

Avec: Hélèna L Denis , Jérôme Lamontagne-Proulx , Isabelle St-Amour , Sarah L Mason , Jesse W Rowley , Nathalie Cloutier , Marie-Ève Tremblay , Antony T Vincent , Peter V Gould , Sylvain Chouinard , Andrew S Weyrich , Matthew T Rondina , Roger A Barker , Eric Boilard , Francesca Cicchetti

Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington's disease pathology.

Journal of neuroinflammation

Avec: Julie C Savage , Marie-Kim St-Pierre , Micaël Carrier , Hassan El Hajj , Sammy Weiser Novak , Maria Gabriela Sanchez , Francesca Cicchetti , Marie-Ève Tremblay

Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates.

Neurobiology of disease

Avec: Alexander Maxan , Giacomo Sciacca , Melanie Alpaugh , Zhu Tao , Ludivine Breger , Benjamin Dehay , Zhang Ling , Qin Chuan , Giulia Cisbani , Maria Masnata , Shireen Salem , Steve Lacroix , Abid Oueslati , Erwan Bezard , Francesca Cicchetti

MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells.

International journal of molecular sciences

Avec: Matteo Cassandri , Silvia Pomella , Alessandra Rossetti , Francesco Petragnano , Luisa Milazzo , Francesca Vulcano , Simona Camero , Silvia Codenotti , Francesca Cicchetti , Roberto Maggio , Claudio Festuccia , Giovanni Luca Gravina , Alessandro Fanzani , Francesca Megiorni , Marialuigia Catanoso , Cinzia Marchese , Vincenzo Tombolini , Franco Locatelli , Rossella Rota , Francesco Marampon

Prompting endogenous repair of brain injury: science fiction or reality?

Molecular neurodegeneration

Avec: Aurelie de Rus Jacquet , Francesca Cicchetti

Evidence of mutant huntingtin and tau-related pathology within neuronal grafts in Huntington's disease cases.

Neurobiology of disease

Avec: Shireen Salem , Mitchell D Kilgore , Mehwish Anwer , Alexander Maxan , Dan Child , Thomas D Bird , C Dirk Keene , Francesca Cicchetti , Caitlin Latimer

Detection of antibodies against the huntingtin protein in human plasma.

Cellular and molecular life sciences : CMLS

Avec: Hélèna L Denis , Melanie Alpaugh , Claudia P Alvarez , Alexis Fenyi , Roger A Barker , Sylvain Chouinard , Cheryl H Arrowsmith , Ronald Melki , Richard Labib , Rachel J Harding , Francesca Cicchetti

Untangling the Role of Tau in Huntington's Disease Pathology.

Journal of Huntington's disease

Avec: Shireen Salem , Francesca Cicchetti

The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson's disease.

Nature communications

Avec: A de Rus Jacquet , M Alpaugh , H L Denis , J L Tancredi , M Boutin , J Decaestecker , C Beauparlant , L Herrmann , M Saint-Pierre , M Parent , A Droit , S Breton , F Cicchetti

Tau: a biomarker of Huntington's disease.

Molecular psychiatry

Avec: Eva Lepinay , Francesca Cicchetti

The Quebec Parkinson Network: A Researcher-Patient Matching Platform and Multimodal Biorepository.

Journal of Parkinson's disease

Avec: Ziv Gan-Or , Trisha Rao , Etienne Leveille , Clotilde Degroot , Sylvain Chouinard , Francesca Cicchetti , Alain Dagher , Samir Das , Alex Desautels , Janelle Drouin-Ouellet , Thomas Durcan , Jean-François Gagnon , Angela Genge , Jason Karamchandani , Anne-Louise Lafontaine , Sonia Lai Wing Sun , Mélanie Langlois , Martin Levesque , Calvin Melmed , Michel Panisset , Martin Parent , Jean-Baptiste Poline , Ronald B Postuma , Emmanuelle Pourcher , Guy A Rouleau , Madeleine Sharp , Oury Monchi , Nicolas Dupré , Edward A Fon

Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms.

Acta neuropathologica

Avec: Maria Masnata , Giacomo Sciacca , Alexander Maxan , Luc Bousset , Hélèna L Denis , Florian Lauruol , Linda David , Martine Saint-Pierre , Jeffrey H Kordower , Ronald Melki , Melanie Alpaugh , Francesca Cicchetti

DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma.

Cells

Avec: Simona Camero , Giulia Vitali , Paola Pontecorvi , Simona Ceccarelli , Eleni Anastasiadou , Francesca Cicchetti , Elisabetta Flex , Silvia Pomella , Matteo Cassandri , Rossella Rota , Francesco Marampon , Cinzia Marchese , Amalia Schiavetti , Francesca Megiorni

Clinical perception and management of Parkinson's disease during the COVID-19 pandemic: A Canadian experience.

Parkinsonism & related disorders

Avec: Aurelie de Rus Jacquet , Sarah Bogard , Catherine P Normandeau , Clotilde Degroot , Ronald B Postuma , Nicolas Dupré , Janis M Miyasaki , Oury Monchi , Davide Martino , Edward A Fon , Francesca Cicchetti

Prion-like properties of the mutant huntingtin protein in living organisms: the evidence and the relevance.

Molecular psychiatry

Avec: Melanie Alpaugh , Hélèna L Denis , Francesca Cicchetti

Targeting Tau to Treat Clinical Features of Huntington's Disease.

Frontiers in neurology

Avec: Maria Masnata , Shireen Salem , Aurelie de Rus Jacquet , Mehwish Anwer , Francesca Cicchetti

Réseau de co-auteurs

Melanie Alpaugh 6 collaborations

Hélèna L Denis 6 collaborations

Alexander Maxan 4 collaborations

Shireen Salem 4 collaborations

Matteo Cassandri 3 collaborations

Silvia Pomella 3 collaborations

Rossella Rota 3 collaborations

Francesco Marampon 3 collaborations

Sylvain Chouinard 3 collaborations

Maria Masnata 3 collaborations

Aurelie de Rus Jacquet 3 collaborations

Eric Boilard 2 collaborations

Steve Lacroix 2 collaborations

Abid Oueslati 2 collaborations

Martine Saint-Pierre 2 collaborations

Alessandra Rossetti 2 collaborations

Francesco Petragnano 2 collaborations

Luisa Milazzo 2 collaborations

Francesca Vulcano 2 collaborations

Silvia Codenotti 2 collaborations

Claudio Festuccia 2 collaborations

Alessandro Fanzani 2 collaborations

Roberto Maggio 2 collaborations

Vincenzo Tombolini 2 collaborations

Giovanni Luca Gravina 2 collaborations

Florian Lauruol 2 collaborations

Marie-Ève Tremblay 2 collaborations

Roger A Barker 2 collaborations

Giacomo Sciacca 2 collaborations

Simona Camero 2 collaborations

Francesca Megiorni 2 collaborations

Cinzia Marchese 2 collaborations

Mehwish Anwer 2 collaborations

Ronald Melki 2 collaborations

Clotilde Degroot 2 collaborations

Ronald B Postuma 2 collaborations

Oury Monchi 2 collaborations

Nicolas Dupré 2 collaborations

Edward A Fon 2 collaborations

Benoit Mailhot 1 collaboration

Marine Christin 1 collaboration

Nicolas Tessandier 1 collaboration

Chaudy Sotoudeh 1 collaboration

Floriane Bretheau 1 collaboration

Roxanne Turmel 1 collaboration

Ève Pellerin 1 collaboration

Feng Wang 1 collaboration

Cyril Bories 1 collaboration

Charles Joly-Beauparlant 1 collaboration

Yves De Koninck 1 collaboration

Arnaud Droit 1 collaboration

Grégory Scherrer 1 collaboration

Reza Sharif-Naeini 1 collaboration

Stefan Bartl 1 collaboration

Amber L Southwell 1 collaboration

Alberto Siddu 1 collaboration

Michela Parth 1 collaboration

Linda Suzanne David 1 collaboration

Nina Salhat 1 collaboration

Markus Burkert 1 collaboration

Andreas Mairhofer 1 collaboration

Theresa Friedrich 1 collaboration

Halyna Pankevych 1 collaboration

Katja Balazs 1 collaboration

Guenther Staffler 1 collaboration

Michael R Hayden 1 collaboration

Oskar W Smrzka 1 collaboration

Marilyn Dubois 1 collaboration

Benoit Aubé 1 collaboration

Dany Arsenault 1 collaboration

Jasna Kriz 1 collaboration

Antonio Cicchetti 1 collaboration

Aurélie de Rus Jacquet 1 collaboration

Giampiero Macioce 1 collaboration

Irene Fasciani 1 collaboration

Cristina Antinozzi 1 collaboration

Luigi Di Luigi 1 collaboration

Francesca De Felice 1 collaboration

Massimo Vergine 1 collaboration

Antonella Polimeni 1 collaboration

Maud Gratuze 1 collaboration

Nicolas Josset 1 collaboration

Franck R Petry 1 collaboration

Mathieu Pflieger 1 collaboration

Laura Eyoum Jong 1 collaboration

Geoffrey Truchetti 1 collaboration

Isabelle Poitras 1 collaboration

Jacinthe Julien 1 collaboration

François Bezeau 1 collaboration

Françoise Morin 1 collaboration

Pershia Samadi 1 collaboration

Frédéric Bretzner 1 collaboration

Emmanuel Planel 1 collaboration

Jérôme Lamontagne-Proulx 1 collaboration

Isabelle St-Amour 1 collaboration

Sarah L Mason 1 collaboration

Jesse W Rowley 1 collaboration

Nathalie Cloutier 1 collaboration

Antony T Vincent 1 collaboration

Peter V Gould 1 collaboration

Andrew S Weyrich 1 collaboration

Matthew T Rondina 1 collaboration

Julie C Savage 1 collaboration

Marie-Kim St-Pierre 1 collaboration

Micaël Carrier 1 collaboration

Hassan El Hajj 1 collaboration

Sammy Weiser Novak 1 collaboration

Maria Gabriela Sanchez 1 collaboration

Zhu Tao 1 collaboration

Ludivine Breger 1 collaboration

Benjamin Dehay 1 collaboration

Zhang Ling 1 collaboration

Qin Chuan 1 collaboration

Giulia Cisbani 1 collaboration

Erwan Bezard 1 collaboration

Marialuigia Catanoso 1 collaboration

Franco Locatelli 1 collaboration

Mitchell D Kilgore 1 collaboration

Dan Child 1 collaboration

Thomas D Bird 1 collaboration

C Dirk Keene 1 collaboration

Caitlin Latimer 1 collaboration

Claudia P Alvarez 1 collaboration

Alexis Fenyi 1 collaboration

Cheryl H Arrowsmith 1 collaboration

Richard Labib 1 collaboration

Rachel J Harding 1 collaboration

A de Rus Jacquet 1 collaboration

M Alpaugh 1 collaboration

H L Denis 1 collaboration

J L Tancredi 1 collaboration

M Boutin 1 collaboration

J Decaestecker 1 collaboration

C Beauparlant 1 collaboration

L Herrmann 1 collaboration

M Saint-Pierre 1 collaboration

M Parent 1 collaboration

A Droit 1 collaboration

S Breton 1 collaboration

F Cicchetti 1 collaboration

Eva Lepinay 1 collaboration

Ziv Gan-Or 1 collaboration

Trisha Rao 1 collaboration

Etienne Leveille 1 collaboration

Alain Dagher 1 collaboration

Samir Das 1 collaboration

Alex Desautels 1 collaboration

Janelle Drouin-Ouellet 1 collaboration

Thomas Durcan 1 collaboration

Jean-François Gagnon 1 collaboration

Angela Genge 1 collaboration

Jason Karamchandani 1 collaboration

Anne-Louise Lafontaine 1 collaboration

Sonia Lai Wing Sun 1 collaboration

Mélanie Langlois 1 collaboration

Martin Levesque 1 collaboration

Calvin Melmed 1 collaboration

Michel Panisset 1 collaboration

Martin Parent 1 collaboration

Jean-Baptiste Poline 1 collaboration

Emmanuelle Pourcher 1 collaboration

Guy A Rouleau 1 collaboration

Madeleine Sharp 1 collaboration

Luc Bousset 1 collaboration

Linda David 1 collaboration

Jeffrey H Kordower 1 collaboration

Giulia Vitali 1 collaboration

Paola Pontecorvi 1 collaboration

Simona Ceccarelli 1 collaboration

Eleni Anastasiadou 1 collaboration

Elisabetta Flex 1 collaboration

Amalia Schiavetti 1 collaboration

Sarah Bogard 1 collaboration

Catherine P Normandeau 1 collaboration

Janis M Miyasaki 1 collaboration

Davide Martino 1 collaboration