Francisco Azuaje

Affiliations

Computational Biomedicine Research Group, Quantitative Biology Unit, Luxembourg Institute of Health, Luxembourg, Luxembourg.

Publications (17)

Extracellular ATP and CD39 Activate cAMP-Mediated Mitochondrial Stress Response to Promote Cytarabine Resistance in Acute Myeloid Leukemia.

Cancer discovery

Avec: Nesrine Aroua , Emeline Boet , Margherita Ghisi , Marie-Laure Nicolau-Travers , Estelle Saland , Ryan Gwilliam , Fabienne de Toni , Mohsen Hosseini , Pierre-Luc Mouchel , Thomas Farge , Claudie Bosc , Lucille Stuani , Marie Sabatier , Fetta Mazed , Clément Larrue , Latifa Jarrou , Sarah Gandarillas , Massimiliano Bardotti , Muriel Picard , Charlotte Syrykh , Camille Laurent , Mathilde Gotanègre , Nathalie Bonnefoy , Floriant Bellvert , Jean-Charles Portais , Nathalie Nicot , Francisco Azuaje , Tony Kaoma , Carine Joffre , Jérome Tamburini , Christian Récher , François Vergez , Jean-Emmanuel Sarry

Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity.

Scientific reports

Avec: Sophie Rodius , Niek de Klein , Céline Jeanty , Héctor Sánchez-Iranzo , Isaac Crespo , Mark Ibberson , Ioannis Xenarios , Gunnar Dittmar , Nadia Mercader , Simone P Niclou , Francisco Azuaje

Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry.

Nature communications

Avec: Amit Kulkarni , Tiago Ferreira , Clemens Bretscher , Annabel Grewenig , Nazim El-Andaloussi , Serena Bonifati , Tiina Marttila , Valérie Palissot , Jubayer A Hossain , Francisco Azuaje , Hrvoje Miletic , Lars A R Ystaas , Anna Golebiewska , Simone P Niclou , Ralf Roeth , Beate Niesler , Amélie Weiss , Laurent Brino , Antonio Marchini

Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice.

Allergy

Avec: Aurélie Poli , Anaïs Oudin , Arnaud Muller , Ilaria Salvato , Andrea Scafidi , Oliver Hunewald , Olivia Domingues , Petr V Nazarov , Vincent Puard , Virginie Baus , Francisco Azuaje , Gunnar Dittmar , Jacques Zimmer , Tatiana Michel , Alessandro Michelucci , Simone P Niclou , Markus Ollert

Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma.

Neuro-oncology

Avec: Jubayer A Hossain , Md A Latif , Lars A R Ystaas , Sandra Ninzima , Kristoffer Riecken , Arnaud Muller , Francisco Azuaje , Justin V Joseph , Krishna M Talasila , Jiwan Ghimire , Boris Fehse , Rolf Bjerkvig , Hrvoje Miletic

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.

Nature communications

Avec: Anne Dirkse , Anna Golebiewska , Thomas Buder , Petr V Nazarov , Arnaud Muller , Suresh Poovathingal , Nicolaas H C Brons , Sonia Leite , Nicolas Sauvageot , Dzjemma Sarkisjan , Mathieu Seyfrid , Sabrina Fritah , Daniel Stieber , Alessandro Michelucci , Frank Hertel , Christel Herold-Mende , Francisco Azuaje , Alexander Skupin , Rolf Bjerkvig , Andreas Deutsch , Anja Voss-Böhme , Simone P Niclou

A deep neural network approach to predicting clinical outcomes of neuroblastoma patients.

BMC medical genomics

Avec: Léon-Charles Tranchevent , Francisco Azuaje , Jagath C Rajapakse

Machine learning-assisted neurotoxicity prediction in human midbrain organoids.

Parkinsonism & related disorders

Avec: Anna S Monzel , Kathrin Hemmer , Tony Kaoma , Lisa M Smits , Silvia Bolognin , Philippe Lucarelli , Isabel Rosety , Alise Zagare , Paul Antony , Sarah L Nickels , Rejko Krueger , Francisco Azuaje , Jens C Schwamborn

Artificial intelligence for precision oncology: beyond patient stratification.

NPJ precision oncology

Avec: Francisco Azuaje

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis.

Acta neuropathologica communications

Avec: Terje Sundstrøm , Lars Prestegarden , Francisco Azuaje , Synnøve Nymark Aasen , Gro Vatne Røsland , Jobin K Varughese , Marzieh Bahador , Simon Bernatz , Yannick Braun , Patrick N Harter , Kai Ove Skaftnesmo , Elizabeth S Ingham , Lisa M Mahakian , Sarah Tam , Clifford G Tepper , Kjell Petersen , Katherine W Ferrara , Karl Johan Tronstad , Morten Lund-Johansen , Rudi Beschorner , Rolf Bjerkvig , Frits Thorsen

Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients.

BMC medical genomics

Avec: Petr V Nazarov , Anke K Wienecke-Baldacchino , Andrei Zinovyev , Urszula Czerwińska , Arnaud Muller , Dorothée Nashan , Gunnar Dittmar , Francisco Azuaje , Stephanie Kreis

Connecting Histopathology Imaging and Proteomics in Kidney Cancer through Machine Learning.

Journal of clinical medicine

Avec: Francisco Azuaje , Sang-Yoon Kim , Daniel Perez Hernandez , Gunnar Dittmar

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.

Acta neuropathologica

Avec: Anna Golebiewska , Ann-Christin Hau , Anaïs Oudin , Daniel Stieber , Yahaya A Yabo , Virginie Baus , Vanessa Barthelemy , Eliane Klein , Sébastien Bougnaud , Olivier Keunen , May Wantz , Alessandro Michelucci , Virginie Neirinckx , Arnaud Muller , Tony Kaoma , Petr V Nazarov , Francisco Azuaje , Alfonso De Falco , Ben Flies , Lorraine Richart , Suresh Poovathingal , Thais Arns , Kamil Grzyb , Andreas Mock , Christel Herold-Mende , Anne Steino , Dennis Brown , Patrick May , Hrvoje Miletic , Tathiane M Malta , Houtan Noushmehr , Yong-Jun Kwon , Winnie Jahn , Barbara Klink , Georgette Tanner , Lucy F Stead , Michel Mittelbronn , Alexander Skupin , Frank Hertel , Rolf Bjerkvig , Simone P Niclou

A Network-Based Embedding Method for Drug-Target Interaction Prediction.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Avec: Poorya Parvizi , Francisco Azuaje , Evropi Theodoratou , Saturnino Luz

Temozolomide-Induced RNA Interactome Uncovers Novel LncRNA Regulatory Loops in Glioblastoma.

Cancers

Avec: Sabrina Fritah , Arnaud Muller , Wei Jiang , Ramkrishna Mitra , Mohamad Sarmini , Monika Dieterle , Anna Golebiewska , Tao Ye , Eric Van Dyck , Christel Herold-Mende , Zhongming Zhao , Francisco Azuaje , Simone P Niclou

DrDimont: explainable drug response prediction from differential analysis of multi-omics networks.

Bioinformatics (Oxford, England)

Avec: Pauline Hiort , Julian Hugo , Justus Zeinert , Nataniel Müller , Spoorthi Kashyap , Jagath C Rajapakse , Francisco Azuaje , Bernhard Y Renard , Katharina Baum

Machine learning for predicting neurodegenerative diseases in the general older population: a cohort study.

BMC medical research methodology

Avec: Gloria A Aguayo , Lu Zhang , Michel Vaillant , Moses Ngari , Magali Perquin , Valerie Moran , Laetitia Huiart , Rejko Krüger , Francisco Azuaje , Cyril Ferdynus , Guy Fagherazzi

Réseau de co-auteurs

Simone P Niclou 6 collaborations

Arnaud Muller 6 collaborations

Gunnar Dittmar 4 collaborations

Anna Golebiewska 4 collaborations

Petr V Nazarov 4 collaborations

Rolf Bjerkvig 4 collaborations

Tony Kaoma 3 collaborations

Hrvoje Miletic 3 collaborations

Alessandro Michelucci 3 collaborations

Christel Herold-Mende 3 collaborations

Jubayer A Hossain 2 collaborations

Lars A R Ystaas 2 collaborations

Anaïs Oudin 2 collaborations

Virginie Baus 2 collaborations

Suresh Poovathingal 2 collaborations

Sabrina Fritah 2 collaborations

Daniel Stieber 2 collaborations

Frank Hertel 2 collaborations

Alexander Skupin 2 collaborations

Jagath C Rajapakse 2 collaborations

Nesrine Aroua 1 collaboration

Emeline Boet 1 collaboration

Margherita Ghisi 1 collaboration

Marie-Laure Nicolau-Travers 1 collaboration

Estelle Saland 1 collaboration

Ryan Gwilliam 1 collaboration

Fabienne de Toni 1 collaboration

Mohsen Hosseini 1 collaboration

Pierre-Luc Mouchel 1 collaboration

Thomas Farge 1 collaboration

Claudie Bosc 1 collaboration

Lucille Stuani 1 collaboration

Marie Sabatier 1 collaboration

Fetta Mazed 1 collaboration

Clément Larrue 1 collaboration

Latifa Jarrou 1 collaboration

Sarah Gandarillas 1 collaboration

Massimiliano Bardotti 1 collaboration

Muriel Picard 1 collaboration

Charlotte Syrykh 1 collaboration

Camille Laurent 1 collaboration

Mathilde Gotanègre 1 collaboration

Nathalie Bonnefoy 1 collaboration

Floriant Bellvert 1 collaboration

Jean-Charles Portais 1 collaboration

Nathalie Nicot 1 collaboration

Carine Joffre 1 collaboration

Jérome Tamburini 1 collaboration

Christian Récher 1 collaboration

François Vergez 1 collaboration

Jean-Emmanuel Sarry 1 collaboration

Sophie Rodius 1 collaboration

Niek de Klein 1 collaboration

Céline Jeanty 1 collaboration

Héctor Sánchez-Iranzo 1 collaboration

Isaac Crespo 1 collaboration

Mark Ibberson 1 collaboration

Ioannis Xenarios 1 collaboration

Nadia Mercader 1 collaboration

Amit Kulkarni 1 collaboration

Tiago Ferreira 1 collaboration

Clemens Bretscher 1 collaboration

Annabel Grewenig 1 collaboration

Nazim El-Andaloussi 1 collaboration

Serena Bonifati 1 collaboration

Tiina Marttila 1 collaboration

Valérie Palissot 1 collaboration

Ralf Roeth 1 collaboration

Beate Niesler 1 collaboration

Amélie Weiss 1 collaboration

Laurent Brino 1 collaboration

Antonio Marchini 1 collaboration

Aurélie Poli 1 collaboration

Ilaria Salvato 1 collaboration

Andrea Scafidi 1 collaboration

Oliver Hunewald 1 collaboration

Olivia Domingues 1 collaboration

Vincent Puard 1 collaboration

Jacques Zimmer 1 collaboration

Tatiana Michel 1 collaboration

Markus Ollert 1 collaboration

Md A Latif 1 collaboration

Sandra Ninzima 1 collaboration

Kristoffer Riecken 1 collaboration

Justin V Joseph 1 collaboration

Krishna M Talasila 1 collaboration

Jiwan Ghimire 1 collaboration

Boris Fehse 1 collaboration

Anne Dirkse 1 collaboration

Thomas Buder 1 collaboration

Nicolaas H C Brons 1 collaboration

Sonia Leite 1 collaboration

Nicolas Sauvageot 1 collaboration

Dzjemma Sarkisjan 1 collaboration

Mathieu Seyfrid 1 collaboration

Andreas Deutsch 1 collaboration

Anja Voss-Böhme 1 collaboration

Léon-Charles Tranchevent 1 collaboration

Anna S Monzel 1 collaboration

Kathrin Hemmer 1 collaboration

Lisa M Smits 1 collaboration

Silvia Bolognin 1 collaboration

Philippe Lucarelli 1 collaboration

Isabel Rosety 1 collaboration

Alise Zagare 1 collaboration

Paul Antony 1 collaboration

Sarah L Nickels 1 collaboration

Rejko Krueger 1 collaboration

Jens C Schwamborn 1 collaboration

Terje Sundstrøm 1 collaboration

Lars Prestegarden 1 collaboration

Synnøve Nymark Aasen 1 collaboration

Gro Vatne Røsland 1 collaboration

Jobin K Varughese 1 collaboration

Marzieh Bahador 1 collaboration

Simon Bernatz 1 collaboration

Yannick Braun 1 collaboration

Patrick N Harter 1 collaboration

Kai Ove Skaftnesmo 1 collaboration

Elizabeth S Ingham 1 collaboration

Lisa M Mahakian 1 collaboration

Sarah Tam 1 collaboration

Clifford G Tepper 1 collaboration

Kjell Petersen 1 collaboration

Katherine W Ferrara 1 collaboration

Karl Johan Tronstad 1 collaboration

Morten Lund-Johansen 1 collaboration

Rudi Beschorner 1 collaboration

Frits Thorsen 1 collaboration

Anke K Wienecke-Baldacchino 1 collaboration

Andrei Zinovyev 1 collaboration

Urszula Czerwińska 1 collaboration

Dorothée Nashan 1 collaboration

Stephanie Kreis 1 collaboration

Sang-Yoon Kim 1 collaboration

Daniel Perez Hernandez 1 collaboration

Ann-Christin Hau 1 collaboration

Yahaya A Yabo 1 collaboration

Vanessa Barthelemy 1 collaboration

Eliane Klein 1 collaboration

Sébastien Bougnaud 1 collaboration

Olivier Keunen 1 collaboration

May Wantz 1 collaboration

Virginie Neirinckx 1 collaboration

Alfonso De Falco 1 collaboration

Ben Flies 1 collaboration

Lorraine Richart 1 collaboration

Thais Arns 1 collaboration

Kamil Grzyb 1 collaboration

Andreas Mock 1 collaboration

Anne Steino 1 collaboration

Dennis Brown 1 collaboration

Patrick May 1 collaboration

Tathiane M Malta 1 collaboration

Houtan Noushmehr 1 collaboration

Yong-Jun Kwon 1 collaboration

Winnie Jahn 1 collaboration

Barbara Klink 1 collaboration

Georgette Tanner 1 collaboration

Lucy F Stead 1 collaboration

Michel Mittelbronn 1 collaboration

Poorya Parvizi 1 collaboration

Evropi Theodoratou 1 collaboration

Saturnino Luz 1 collaboration

Wei Jiang 1 collaboration

Ramkrishna Mitra 1 collaboration

Mohamad Sarmini 1 collaboration

Monika Dieterle 1 collaboration

Tao Ye 1 collaboration

Eric Van Dyck 1 collaboration

Zhongming Zhao 1 collaboration

Pauline Hiort 1 collaboration

Julian Hugo 1 collaboration

Justus Zeinert 1 collaboration

Nataniel Müller 1 collaboration

Spoorthi Kashyap 1 collaboration

Bernhard Y Renard 1 collaboration

Katharina Baum 1 collaboration

Gloria A Aguayo 1 collaboration

Lu Zhang 1 collaboration

Michel Vaillant 1 collaboration

Moses Ngari 1 collaboration

Magali Perquin 1 collaboration

Valerie Moran 1 collaboration

Laetitia Huiart 1 collaboration

Rejko Krüger 1 collaboration

Cyril Ferdynus 1 collaboration

Guy Fagherazzi 1 collaboration