Gregory J Pazour

Affiliations

Program in Molecular Medicine, University of Massachusetts Medical School, Biotech II, Suite 213, 373 Plantation Street, Worcester, MA 01605, United States of America. Electronic address: gregory.pazour@umassmed.edu.

Publications (30)

Cilia in cystic kidney and other diseases.

Cellular signalling

Avec: Gregory J Pazour , Lynne Quarmby , Abigail O Smith , Paurav B Desai , Miriam Schmidts

Autonomous and non-cell autonomous etiology of ciliopathy associated structural birth defects.

bioRxiv : the preprint server for biology

Avec: Richard Francis , Jovenal T San Agustin , Heather L Szabo Rogers , Cheng Cui , Julie A Jonassen , Thibaut Eguether , John A Follit , Cecilia W Lo , Gregory J Pazour

The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in pre-cystic epithelial cells revealing a new target for polycystic kidney disease.

medRxiv : the preprint server for health sciences

Avec: Abigail O Smith , William Tyler Frantz , Kenley M Preval , Yvonne J K Edwards , Craig J Ceol , Julie A Jonassen , Gregory J Pazour

Contribution of intraflagellar transport to compartmentalization and maintenance of the photoreceptor cell.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Tylor R Lewis , Carson M Castillo , Natalia V Klementieva , Ying Hsu , Ying Hao , William J Spencer , Arlene V Drack , Gregory J Pazour , Vadim Y Arshavsky

X Caps the Phosphate for Phospho-Rab GTPase Recognition in Ciliogenesis and Parkinson's Disease.

Structure (London, England : 1993)

Avec: Michael W Struck , Gregory J Pazour , David G Lambright

E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened.

The Journal of cell biology

Avec: Bo Lv , Michael W Stuck , Paurav B Desai , Oscar A Cabrera , Gregory J Pazour

Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis.

Scientific reports

Avec: Benjamin Cyge , Vera Voronina , Mohammed Hoque , Eunice N Kim , Jason Hall , Jennifer M Bailey-Lundberg , Gregory J Pazour , Howard C Crawford , Randall T Moon , Feng-Qian Li , Ken-Ichi Takemaru

Biallelic pathogenic variants in roundabout guidance receptor 1 associate with syndromic congenital anomalies of the kidney and urinary tract.

Kidney international

Avec: Johannes Münch , Marie Engesser , Ria Schönauer , J Austin Hamm , Christin Hartig , Elena Hantmann , Gulsen Akay , Davut Pehlivan , Tadahiro Mitani , Zeynep Coban Akdemir , Beyhan Tüysüz , Toshihiko Shirakawa , Sumito Dateki , Laura R Claus , Albertien M van Eerde , Auteur inconnu , Thomas Smol , Louise Devisme , Hélène Franquet , Tania Attié-Bitach , Timo Wagner , Carsten Bergmann , Anne Kathrin Höhn , Shirlee Shril , Ari Pollack , Tara Wenger , Abbey A Scott , Sarah Paolucci , Jillian Buchan , George C Gabriel , Jennifer E Posey , James R Lupski , Florence Petit , Andrew A McCarthy , Gregory J Pazour , Cecilia W Lo , Bernt Popp , Jan Halbritter

c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease.

PLoS genetics

Avec: Abigail O Smith , Julie A Jonassen , Kenley M Preval , Roger J Davis , Gregory J Pazour

Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse.

Nature communications

Avec: Andres Ernesto Zucchetti , Laurence Bataille , Jean-Marie Carpier , Stéphanie Dogniaux , Mabel San Roman-Jouve , Mathieu Maurin , Michael W Stuck , Rosa M Rios , Cosima T Baldari , Gregory J Pazour , Claire Hivroz

WormCat: An Online Tool for Annotation and Visualization of

Genetics

Avec: Amy D Holdorf , Daniel P Higgins , Anne C Hart , Peter R Boag , Gregory J Pazour , Albertha J M Walhout , Amy K Walker

medRxiv : the preprint server for health sciences

Avec: Zeineb Bakey , Oscar A Cabrera , Julia Hoefele , Dinu Antony , Kaman Wu , Michael W Stuck , Dimitra Micha , Thibaut Eguether , Abigail O Smith , Nicole N van der Wel , Matias Wagner , Lara Strittmatter , Philip L Beales , Julie A Jonassen , Isabelle Thiffault , Maxime Cadieux-Dion , Laura Boyes , Saba Sharif , Beyhan Tüysüz , Desiree Dunstheimer , Hans W M Niessen , William Devine , Cecilia W Lo , Hannah M Mitchison , Miriam Schmidts , Gregory J Pazour

Autonomous and non-cell autonomous role of cilia in structural birth defects in mice.

PLoS biology

Avec: Richard J B Francis , Jovenal T San Agustin , Heather L Szabo Rogers , Cheng Cui , Julie A Jonassen , Thibaut Eguether , John A Follit , Cecilia W Lo , Gregory J Pazour

Intraflagellar transport: A critical player in photoreceptor development and the pathogenesis of retinal degenerative diseases.

Cytoskeleton (Hoboken, N.J.)

Avec: Mohona Gupta , Gregory J Pazour

Abnormal fertility, acrosome formation, IFT20 expression and localization in conditional

American journal of physiology. Cell physiology

Avec: Zhenyu Wang , Yuqin Shi , Suheng Ma , Qian Huang , Yi Tian Yap , Lin Shi , Shiyang Zhang , Ting Zhou , Wei Li , Bo Hu , Ling Zhang , Stephen A Krawetz , Gregory J Pazour , Rex A Hess , Zhibing Zhang

Ciliary Doublet Microtubules at Near-Atomic Resolution.

Cell

Avec: Gregory J Pazour , Stephen M King

A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia.

Journal of cell science

Avec: Tyler Picariello , Jason M Brown , Yuqing Hou , Gregory Swank , Deborah A Cochran , Oliver D King , Karl Lechtreck , Gregory J Pazour , George B Witman

c-JUN n-Terminal Kinase (JNK) Signaling in Autosomal Dominant Polycystic Kidney Disease.

Journal of cellular signaling

Avec: Abigail O Smith , Julie A Jonassen , Kenley M Preval , Roger J Davis , Gregory J Pazour

Arih2 regulates Hedgehog signaling through smoothened ubiquitylation and ER-associated degradation.

Journal of cell science

Avec: Bo Lv , Xiao-Ou Zhang , Gregory J Pazour

IFT74 variants cause skeletal ciliopathy and motile cilia defects in mice and humans.

PLoS genetics

Inpp5e is a Critical Regulator of Protein Transport to Photoreceptor Outer Segments.

bioRxiv : the preprint server for biology

Avec: Mohona Gupta , Tylor R Lewis , Michael W Stuck , William J Spencer , Natasha Klementeva , Vadim Y Arshavsky , Gregory J Pazour

Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.

The Journal of cell biology

Avec: Paurav B Desai , Michael W Stuck , Bo Lv , Gregory J Pazour

Allelic Diversity in the Serum Amyloid A2 Gene and Amyloid A Amyloidosis in a Breeding Colony of Zebra Finches (

Comparative medicine

Avec: Lisa J Shientag , Oscar A Cabrera , Gregory J Pazour

Hypomorphic mutations of TRIP11 cause odontochondrodysplasia.

JCI insight

Avec: Anika Wehrle , Tomasz M Witkos , Sheila Unger , Judith Schneider , John A Follit , Johannes Hermann , Tim Welting , Virginia Fano , Marja Hietala , Nithiwat Vatanavicharn , Katharina Schoner , Jürgen Spranger , Miriam Schmidts , Bernhard Zabel , Gregory J Pazour , Agnes Bloch-Zupan , Gen Nishimura , Andrea Superti-Furga , Martin Lowe , Ekkehart Lausch

Intraflagellar transport protein 74 is essential for spermatogenesis and male fertility in mice†.

Biology of reproduction

Avec: Lin Shi , Ting Zhou , Qian Huang , Shiyang Zhang , Wei Li , Ling Zhang , Rex A Hess , Gregory J Pazour , Zhibing Zhang

Consensus nomenclature for dyneins and associated assembly factors.

The Journal of cell biology

Avec: Bryony Braschi , Heymut Omran , George B Witman , Gregory J Pazour , K Kevin Pfister , Elspeth A Bruford , Stephen M King

Rab34 is necessary for early stages of intracellular ciliogenesis.

Current biology : CB

Avec: Michael W Stuck , Weng Man Chong , Jung-Chi Liao , Gregory J Pazour

Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation.

Frontiers in cell and developmental biology

Avec: Delayna Paulson , Rebecca Harms , Cody Ward , Mackenzie Latterell , Gregory J Pazour , Darci M Fink

A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation.

EMBO reports

Avec: Jan N Hansen , Fabian Kaiser , Philipp Leyendecker , Birthe Stüven , Jens-Henning Krause , Fatemeh Derakhshandeh , Jaazba Irfan , Tommy J Sroka , Kenley M Preval , Paurav B Desai , Michael Kraut , Heidi Theis , Anna-Dorothee Drews , Elena De-Domenico , Kristian Händler , Gregory J Pazour , David J P Henderson , David U Mick , Dagmar Wachten

Cilia Structure and Function in Human Disease.

Current opinion in endocrine and metabolic research

Avec: Gregory J Pazour

Réseau de co-auteurs

Julie A Jonassen 7 collaborations

Michael W Stuck 7 collaborations

Abigail O Smith 6 collaborations

Cecilia W Lo 5 collaborations

Paurav B Desai 4 collaborations

Miriam Schmidts 4 collaborations

Thibaut Eguether 4 collaborations

Kenley M Preval 4 collaborations

Oscar A Cabrera 4 collaborations

John A Follit 3 collaborations

Bo Lv 3 collaborations

Beyhan Tüysüz 3 collaborations

Jovenal T San Agustin 2 collaborations

Heather L Szabo Rogers 2 collaborations

Cheng Cui 2 collaborations

Tylor R Lewis 2 collaborations

William J Spencer 2 collaborations

Vadim Y Arshavsky 2 collaborations

Roger J Davis 2 collaborations

Zeineb Bakey 2 collaborations

Julia Hoefele 2 collaborations

Dinu Antony 2 collaborations

Kaman Wu 2 collaborations

Dimitra Micha 2 collaborations

Nicole N van der Wel 2 collaborations

Matias Wagner 2 collaborations

Lara Strittmatter 2 collaborations

Philip L Beales 2 collaborations

Isabelle Thiffault 2 collaborations

Maxime Cadieux-Dion 2 collaborations

Laura Boyes 2 collaborations

Saba Sharif 2 collaborations

Desiree Dunstheimer 2 collaborations

Hans W M Niessen 2 collaborations

William Devine 2 collaborations

Hannah M Mitchison 2 collaborations

Mohona Gupta 2 collaborations

Qian Huang 2 collaborations

Lin Shi 2 collaborations

Shiyang Zhang 2 collaborations

Ting Zhou 2 collaborations

Wei Li 2 collaborations

Ling Zhang 2 collaborations

Rex A Hess 2 collaborations

Zhibing Zhang 2 collaborations

Stephen M King 2 collaborations

George B Witman 2 collaborations

Lynne Quarmby 1 collaboration

Richard Francis 1 collaboration

William Tyler Frantz 1 collaboration

Yvonne J K Edwards 1 collaboration

Craig J Ceol 1 collaboration

Carson M Castillo 1 collaboration

Natalia V Klementieva 1 collaboration

Ying Hsu 1 collaboration

Ying Hao 1 collaboration

Arlene V Drack 1 collaboration

Michael W Struck 1 collaboration

David G Lambright 1 collaboration

Benjamin Cyge 1 collaboration

Vera Voronina 1 collaboration

Mohammed Hoque 1 collaboration

Eunice N Kim 1 collaboration

Jason Hall 1 collaboration

Jennifer M Bailey-Lundberg 1 collaboration

Howard C Crawford 1 collaboration

Randall T Moon 1 collaboration

Feng-Qian Li 1 collaboration

Ken-Ichi Takemaru 1 collaboration

Johannes Münch 1 collaboration

Marie Engesser 1 collaboration

Ria Schönauer 1 collaboration

J Austin Hamm 1 collaboration

Christin Hartig 1 collaboration

Elena Hantmann 1 collaboration

Gulsen Akay 1 collaboration

Davut Pehlivan 1 collaboration

Tadahiro Mitani 1 collaboration

Zeynep Coban Akdemir 1 collaboration

Toshihiko Shirakawa 1 collaboration

Sumito Dateki 1 collaboration

Laura R Claus 1 collaboration

Albertien M van Eerde 1 collaboration

None None 1 collaboration

Thomas Smol 1 collaboration

Louise Devisme 1 collaboration

Hélène Franquet 1 collaboration

Tania Attié-Bitach 1 collaboration

Timo Wagner 1 collaboration

Carsten Bergmann 1 collaboration

Anne Kathrin Höhn 1 collaboration

Shirlee Shril 1 collaboration

Ari Pollack 1 collaboration

Tara Wenger 1 collaboration

Abbey A Scott 1 collaboration

Sarah Paolucci 1 collaboration

Jillian Buchan 1 collaboration

George C Gabriel 1 collaboration

Jennifer E Posey 1 collaboration

James R Lupski 1 collaboration

Florence Petit 1 collaboration

Andrew A McCarthy 1 collaboration

Bernt Popp 1 collaboration

Jan Halbritter 1 collaboration

Andres Ernesto Zucchetti 1 collaboration

Laurence Bataille 1 collaboration

Jean-Marie Carpier 1 collaboration

Stéphanie Dogniaux 1 collaboration

Mabel San Roman-Jouve 1 collaboration

Mathieu Maurin 1 collaboration

Rosa M Rios 1 collaboration

Cosima T Baldari 1 collaboration

Claire Hivroz 1 collaboration

Amy D Holdorf 1 collaboration

Daniel P Higgins 1 collaboration

Anne C Hart 1 collaboration

Peter R Boag 1 collaboration

Albertha J M Walhout 1 collaboration

Amy K Walker 1 collaboration

Richard J B Francis 1 collaboration

Zhenyu Wang 1 collaboration

Yuqin Shi 1 collaboration

Suheng Ma 1 collaboration

Yi Tian Yap 1 collaboration

Bo Hu 1 collaboration

Stephen A Krawetz 1 collaboration

Tyler Picariello 1 collaboration

Jason M Brown 1 collaboration

Yuqing Hou 1 collaboration

Gregory Swank 1 collaboration

Deborah A Cochran 1 collaboration

Oliver D King 1 collaboration

Karl Lechtreck 1 collaboration

Xiao-Ou Zhang 1 collaboration

Natasha Klementeva 1 collaboration

Lisa J Shientag 1 collaboration

Anika Wehrle 1 collaboration

Tomasz M Witkos 1 collaboration

Sheila Unger 1 collaboration

Judith Schneider 1 collaboration

Johannes Hermann 1 collaboration

Tim Welting 1 collaboration

Virginia Fano 1 collaboration

Marja Hietala 1 collaboration

Nithiwat Vatanavicharn 1 collaboration

Katharina Schoner 1 collaboration

Jürgen Spranger 1 collaboration

Bernhard Zabel 1 collaboration

Agnes Bloch-Zupan 1 collaboration

Gen Nishimura 1 collaboration

Andrea Superti-Furga 1 collaboration

Martin Lowe 1 collaboration

Ekkehart Lausch 1 collaboration

Bryony Braschi 1 collaboration

Heymut Omran 1 collaboration

K Kevin Pfister 1 collaboration

Elspeth A Bruford 1 collaboration

Weng Man Chong 1 collaboration

Jung-Chi Liao 1 collaboration

Delayna Paulson 1 collaboration

Rebecca Harms 1 collaboration

Cody Ward 1 collaboration

Mackenzie Latterell 1 collaboration

Darci M Fink 1 collaboration

Jan N Hansen 1 collaboration

Fabian Kaiser 1 collaboration

Philipp Leyendecker 1 collaboration

Birthe Stüven 1 collaboration

Jens-Henning Krause 1 collaboration

Fatemeh Derakhshandeh 1 collaboration

Jaazba Irfan 1 collaboration

Tommy J Sroka 1 collaboration

Michael Kraut 1 collaboration

Heidi Theis 1 collaboration

Anna-Dorothee Drews 1 collaboration

Elena De-Domenico 1 collaboration

Kristian Händler 1 collaboration

David J P Henderson 1 collaboration

David U Mick 1 collaboration

Dagmar Wachten 1 collaboration