I Alecu

Affiliations

Neural Regeneration Laboratory, India Taylor Lipidomic Research Platform, Department of Biochemistry, Microbiology and Immunology, Ottawa Institute of Systems Biology, Ottawa Brain and Mind Research Institute, University of Ottawa, Canada.

Publications (15)

Dysregulated Lipid Metabolism and Its Role in α-Synucleinopathy in Parkinson's Disease.

Frontiers in neuroscience

Avec: Irina Alecu , Steffany A L Bennett

Signed Distance Correlation (SiDCo): an online implementation of distance correlation and partial distance correlation for data-driven network analysis.

Bioinformatics (Oxford, England)

Avec: Francesco Monti , David Stewart , Anuradha Surendra , Irina Alecu , Thao Nguyen-Tran , Steffany A L Bennett , Miroslava Čuperlović-Culf

Oxidative stress increases 1-deoxysphingolipid levels in chronic kidney disease.

Free radical biology & medicine

Avec: Ting Gui , Yunlun Li , Shijun Zhang , Irina Alecu , Qingfa Chen , Ying Zhao , Thorsten Hornemann , Gerd A Kullak-Ublick , Zhibo Gai

BATL: Bayesian annotations for targeted lipidomics.

Bioinformatics (Oxford, England)

Avec: Justin G Chitpin , Anuradha Surendra , Thao T Nguyen , Graeme P Taylor , Hongbin Xu , Irina Alecu , Roberto Ortega , Julianna J Tomlinson , Angela M Crawley , Michaeline McGuinty , Michael G Schlossmacher , Rachel Saunders-Pullman , Miroslava Cuperlovic-Culf , Steffany A L Bennett , Theodore J Perkins

Epithelioid neoplasm of the spinal cord in a child with spinal muscular atrophy treated with onasemnogene abeparvovec.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Laura Retson , Nishant Tiwari , Jennifer Vaughn , Saunder Bernes , P David Adelson , Keith Mansfield , Silvana Libertini , Brent Kuzmiski , Iulian Alecu , Richard Gabriel , Ross Mangum

Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards.

Nature communications

Avec: Federico Torta , Nils Hoffmann , Bo Burla , Irina Alecu , Makoto Arita , Takeshi Bamba , Steffany A L Bennett , Justine Bertrand-Michel , Britta Brügger , Mónica P Cala , Dolores Camacho-Muñoz , Antonio Checa , Michael Chen , Michaela Chocholoušková , Michelle Cinel , Emeline Chu-Van , Benoit Colsch , Cristina Coman , Lisa Connell , Bebiana C Sousa , Alex M Dickens , Maria Fedorova , Finnur Freyr Eiríksson , Hector Gallart-Ayala , Mohan Ghorasaini , Martin Giera , Xue Li Guan , Mark Haid , Thomas Hankemeier , Amy Harms , Marcus Höring , Michal Holčapek , Thorsten Hornemann , Chunxiu Hu , Andreas J Hülsmeier , Kevin Huynh , Christina M Jones , Julijana Ivanisevic , Yoshihiro Izumi , Harald C Köfeler , Sin Man Lam , Mike Lange , Jong Cheol Lee , Gerhard Liebisch , Katrice Lippa , Andrea F Lopez-Clavijo , Malena Manzi , Manuela R Martinefski , Raviswamy G H Math , Satyajit Mayor , Peter J Meikle , María Eugenia Monge , Myeong Hee Moon , Sneha Muralidharan , Anna Nicolaou , Thao Nguyen-Tran , Valerie B O'Donnell , Matej Orešič , Arvind Ramanathan , Fabien Riols , Daisuke Saigusa , Tracey B Schock , Heidi Schwartz-Zimmermann , Guanghou Shui , Madhulika Singh , Masatomo Takahashi , Margrét Thorsteinsdóttir , Noriyuki Tomiyasu , Anthony Tournadre , Hiroshi Tsugawa , Victoria J Tyrrell , Grace van der Gugten , Michael O Wakelam , Craig E Wheelock , Denise Wolrab , Guowang Xu , Tianrun Xu , John A Bowden , Kim Ekroos , Robert Ahrends , Markus R Wenk

1-Deoxysphingolipids.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: M A Lone , T Santos , I Alecu , L C Silva , T Hornemann

1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development.

Developmental cell

Avec: Ting Wang , Zheng Wang , Lauriane de Fabritus , Jinglian Tao , Essa M Saied , Ho-Joon Lee , Bulat R Ramazanov , Benjamin Jackson , Daniel Burkhardt , Mikhail Parker , Anne S Gleinich , Zhirui Wang , Dong Eun Seo , Ting Zhou , Shihao Xu , Irina Alecu , Parastoo Azadi , Christoph Arenz , Thorsten Hornemann , Smita Krishnaswamy , Serge A van de Pavert , Susan M Kaech , Natalia B Ivanova , Fabio R Santori

Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity.

EBioMedicine

Avec: Chantal A Pileggi , Denis P Blondin , Breana G Hooks , Gaganvir Parmar , Irina Alecu , David A Patten , Alexanne Cuillerier , Conor O'Dwyer , A Brianne Thrush , Morgan D Fullerton , Steffany Al Bennett , Éric Doucet , François Haman , Miroslava Cuperlovic-Culf , Ruth McPherson , Robert R M Dent , Mary-Ellen Harper

Loss of Dnajc21 leads to cytopenia and altered nucleotide metabolism in zebrafish.

Leukemia

Avec: Sarada Ketharnathan , Sujata Pokharel , Sergey V Prykhozhij , Anna Cordeiro-Santanach , Kevin Ban , Serkan Dogan , Huy-Dung Hoang , Mira F Liebman , Elaine Leung , Tommy Alain , Irina Alecu , Steffany A L Bennett , Miroslava Čuperlović-Culf , Yigal Dror , Jason N Berman

Farnesoid X receptor activation induces the degradation of hepatotoxic 1-deoxysphingolipids in non-alcoholic fatty liver disease.

Liver international : official journal of the International Association for the Study of the Liver

Avec: Zhibo Gai , Ting Gui , Irina Alecu , Museer A Lone , Thorsten Hornemann , Qingfa Chen , Michele Visentin , Christian Hiller , Stephanie Hausler , Gerd A Kullak-Ublick

Serine palmitoyltransferase assembles at ER-mitochondria contact sites.

Life science alliance

Avec: Mari J Aaltonen , Irina Alecu , Tim König , Steffany Al Bennett , Eric A Shoubridge

Plasma Sphingoid Base Profiles of Patients Diagnosed with Intrinsic or Idiosyncratic Drug-induced Liver Injury.

International journal of molecular sciences

Avec: Zhibo Gai , Sophia L Samodelov , Irina Alecu , Thorsten Hornemann , Jane I Grove , Guruprasad P Aithal , Michele Visentin , Gerd A Kullak-Ublick

Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.

PLoS pathogens

Avec: Peyman Ghorbani , Sang Yong Kim , Tyler K T Smith , Lucía Minarrieta , Victoria Robert-Gostlin , Marisa K Kilgour , Maja Ilijevska , Irina Alecu , Shayne A Snider , Kaitlyn D Margison , Julia R C Nunes , Daniel Woo , Ciara Pember , Conor O'Dwyer , Julie Ouellette , Pavel Kotchetkov , Julie St-Pierre , Steffany A L Bennett , Baptiste Lacoste , Alexandre Blais , Meera G Nair , Morgan D Fullerton

The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics.

Current research in neurobiology

Avec: Chantal A Pileggi , Gaganvir Parmar , Hussein Elkhatib , Corina M Stewart , Irina Alecu , Marceline Côté , Steffany A L Bennett , Jagdeep K Sandhu , Miroslava Cuperlovic-Culf , Mary-Ellen Harper

Réseau de co-auteurs

Irina Alecu 13 collaborations

Steffany A L Bennett 7 collaborations

Thorsten Hornemann 5 collaborations

Gerd A Kullak-Ublick 3 collaborations

Zhibo Gai 3 collaborations

Miroslava Cuperlovic-Culf 3 collaborations

Anuradha Surendra 2 collaborations

Thao Nguyen-Tran 2 collaborations

Miroslava Čuperlović-Culf 2 collaborations

Ting Gui 2 collaborations

Qingfa Chen 2 collaborations

Chantal A Pileggi 2 collaborations

Gaganvir Parmar 2 collaborations

Conor O'Dwyer 2 collaborations

Morgan D Fullerton 2 collaborations

Steffany Al Bennett 2 collaborations

Mary-Ellen Harper 2 collaborations

Michele Visentin 2 collaborations

Francesco Monti 1 collaboration

David Stewart 1 collaboration

Yunlun Li 1 collaboration

Shijun Zhang 1 collaboration

Ying Zhao 1 collaboration

Justin G Chitpin 1 collaboration

Thao T Nguyen 1 collaboration

Graeme P Taylor 1 collaboration

Hongbin Xu 1 collaboration

Roberto Ortega 1 collaboration

Julianna J Tomlinson 1 collaboration

Angela M Crawley 1 collaboration

Michaeline McGuinty 1 collaboration

Michael G Schlossmacher 1 collaboration

Rachel Saunders-Pullman 1 collaboration

Theodore J Perkins 1 collaboration

Laura Retson 1 collaboration

Nishant Tiwari 1 collaboration

Jennifer Vaughn 1 collaboration

Saunder Bernes 1 collaboration

P David Adelson 1 collaboration

Keith Mansfield 1 collaboration

Silvana Libertini 1 collaboration

Brent Kuzmiski 1 collaboration

Iulian Alecu 1 collaboration

Richard Gabriel 1 collaboration

Ross Mangum 1 collaboration

Federico Torta 1 collaboration

Nils Hoffmann 1 collaboration

Bo Burla 1 collaboration

Makoto Arita 1 collaboration

Takeshi Bamba 1 collaboration

Justine Bertrand-Michel 1 collaboration

Britta Brügger 1 collaboration

Mónica P Cala 1 collaboration

Dolores Camacho-Muñoz 1 collaboration

Antonio Checa 1 collaboration

Michael Chen 1 collaboration

Michaela Chocholoušková 1 collaboration

Michelle Cinel 1 collaboration

Emeline Chu-Van 1 collaboration

Benoit Colsch 1 collaboration

Cristina Coman 1 collaboration

Lisa Connell 1 collaboration

Bebiana C Sousa 1 collaboration

Alex M Dickens 1 collaboration

Maria Fedorova 1 collaboration

Finnur Freyr Eiríksson 1 collaboration

Hector Gallart-Ayala 1 collaboration

Mohan Ghorasaini 1 collaboration

Martin Giera 1 collaboration

Xue Li Guan 1 collaboration

Mark Haid 1 collaboration

Thomas Hankemeier 1 collaboration

Amy Harms 1 collaboration

Marcus Höring 1 collaboration

Michal Holčapek 1 collaboration

Chunxiu Hu 1 collaboration

Andreas J Hülsmeier 1 collaboration

Kevin Huynh 1 collaboration

Christina M Jones 1 collaboration

Julijana Ivanisevic 1 collaboration

Yoshihiro Izumi 1 collaboration

Harald C Köfeler 1 collaboration

Sin Man Lam 1 collaboration

Mike Lange 1 collaboration

Jong Cheol Lee 1 collaboration

Gerhard Liebisch 1 collaboration

Katrice Lippa 1 collaboration

Andrea F Lopez-Clavijo 1 collaboration

Malena Manzi 1 collaboration

Manuela R Martinefski 1 collaboration

Raviswamy G H Math 1 collaboration

Satyajit Mayor 1 collaboration

Peter J Meikle 1 collaboration

María Eugenia Monge 1 collaboration

Myeong Hee Moon 1 collaboration

Sneha Muralidharan 1 collaboration

Anna Nicolaou 1 collaboration

Valerie B O'Donnell 1 collaboration

Matej Orešič 1 collaboration

Arvind Ramanathan 1 collaboration

Fabien Riols 1 collaboration

Daisuke Saigusa 1 collaboration

Tracey B Schock 1 collaboration

Heidi Schwartz-Zimmermann 1 collaboration

Guanghou Shui 1 collaboration

Madhulika Singh 1 collaboration

Masatomo Takahashi 1 collaboration

Margrét Thorsteinsdóttir 1 collaboration

Noriyuki Tomiyasu 1 collaboration

Anthony Tournadre 1 collaboration

Hiroshi Tsugawa 1 collaboration

Victoria J Tyrrell 1 collaboration

Grace van der Gugten 1 collaboration

Michael O Wakelam 1 collaboration

Craig E Wheelock 1 collaboration

Denise Wolrab 1 collaboration

Guowang Xu 1 collaboration

Tianrun Xu 1 collaboration

John A Bowden 1 collaboration

Kim Ekroos 1 collaboration

Robert Ahrends 1 collaboration

Markus R Wenk 1 collaboration

M A Lone 1 collaboration

T Santos 1 collaboration

L C Silva 1 collaboration

T Hornemann 1 collaboration

Ting Wang 1 collaboration

Zheng Wang 1 collaboration

Lauriane de Fabritus 1 collaboration

Jinglian Tao 1 collaboration

Essa M Saied 1 collaboration

Ho-Joon Lee 1 collaboration

Bulat R Ramazanov 1 collaboration

Benjamin Jackson 1 collaboration

Daniel Burkhardt 1 collaboration

Mikhail Parker 1 collaboration

Anne S Gleinich 1 collaboration

Zhirui Wang 1 collaboration

Dong Eun Seo 1 collaboration

Ting Zhou 1 collaboration

Shihao Xu 1 collaboration

Parastoo Azadi 1 collaboration

Christoph Arenz 1 collaboration

Smita Krishnaswamy 1 collaboration

Serge A van de Pavert 1 collaboration

Susan M Kaech 1 collaboration

Natalia B Ivanova 1 collaboration

Fabio R Santori 1 collaboration

Denis P Blondin 1 collaboration

Breana G Hooks 1 collaboration

David A Patten 1 collaboration

Alexanne Cuillerier 1 collaboration

A Brianne Thrush 1 collaboration

Éric Doucet 1 collaboration

François Haman 1 collaboration

Ruth McPherson 1 collaboration

Robert R M Dent 1 collaboration

Sarada Ketharnathan 1 collaboration

Sujata Pokharel 1 collaboration

Sergey V Prykhozhij 1 collaboration

Anna Cordeiro-Santanach 1 collaboration

Kevin Ban 1 collaboration

Serkan Dogan 1 collaboration

Huy-Dung Hoang 1 collaboration

Mira F Liebman 1 collaboration

Elaine Leung 1 collaboration

Tommy Alain 1 collaboration

Yigal Dror 1 collaboration

Jason N Berman 1 collaboration

Museer A Lone 1 collaboration

Christian Hiller 1 collaboration

Stephanie Hausler 1 collaboration

Mari J Aaltonen 1 collaboration

Tim König 1 collaboration

Eric A Shoubridge 1 collaboration

Sophia L Samodelov 1 collaboration

Jane I Grove 1 collaboration

Guruprasad P Aithal 1 collaboration

Peyman Ghorbani 1 collaboration

Sang Yong Kim 1 collaboration

Tyler K T Smith 1 collaboration

Lucía Minarrieta 1 collaboration

Victoria Robert-Gostlin 1 collaboration

Marisa K Kilgour 1 collaboration

Maja Ilijevska 1 collaboration

Shayne A Snider 1 collaboration

Kaitlyn D Margison 1 collaboration

Julia R C Nunes 1 collaboration

Daniel Woo 1 collaboration

Ciara Pember 1 collaboration

Julie Ouellette 1 collaboration

Pavel Kotchetkov 1 collaboration

Julie St-Pierre 1 collaboration

Baptiste Lacoste 1 collaboration

Alexandre Blais 1 collaboration

Meera G Nair 1 collaboration

Hussein Elkhatib 1 collaboration

Corina M Stewart 1 collaboration

Marceline Côté 1 collaboration

Jagdeep K Sandhu 1 collaboration