Jan E Carette

Affiliations

Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.

ORCID: http://orcid.org/0000-0002-5187-8070

Publications (23)

Lipid droplets can promote drug accumulation and activation.

Nature chemical biology

Avec: Ramin Dubey , Craig E Stivala , Huy Quoc Nguyen , Young-Hwa Goo , Antoni Paul , Jan E Carette , Barry M Trost , Rajat Rohatgi

Capsid Engineering Overcomes Barriers Toward Adeno-Associated Virus Vector-Mediated Transduction of Endothelial Cells.

Human gene therapy

Avec: L Zhang , A Rossi , L Lange , N Meumann , U Koitzsch , K Christie , M A Nesbit , C B T Moore , U T Hacker , M Morgan , D Hoffmann , J Zengel , J E Carette , A Schambach , A Salvetti , M Odenthal , H Büning

Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Gustavo de Alencastro , Francesco Puzzo , Mara Pavel-Dinu , Feijie Zhang , Sirika Pillay , Karim Majzoub , Matthew Tiffany , Hagoon Jang , Adam Sheikali , M Kyle Cromer , Ruhikanta Meetei , Jan E Carette , Matthew H Porteus , Katja Pekrun , Mark A Kay

Return of the Neurotropic Enteroviruses: Co-Opting Cellular Pathways for Infection.

Viruses

Avec: Christine E Peters , Jan E Carette

Small RNAs are modified with N-glycans and displayed on the surface of living cells.

Cell

Avec: Ryan A Flynn , Kayvon Pedram , Stacy A Malaker , Pedro J Batista , Benjamin A H Smith , Alex G Johnson , Benson M George , Karim Majzoub , Peter W Villalta , Jan E Carette , Carolyn R Bertozzi

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses.

Cell

Avec: Ruofan Wang , Camille R Simoneau , Jessie Kulsuptrakul , Mehdi Bouhaddou , Katherine A Travisano , Jennifer M Hayashi , Jared Carlson-Stevermer , James R Zengel , Christopher M Richards , Parinaz Fozouni , Jennifer Oki , Lauren Rodriguez , Bastian Joehnk , Keith Walcott , Kevin Holden , Anita Sil , Jan E Carette , Nevan J Krogan , Melanie Ott , Andreas S Puschnik

GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry.

Molecular therapy. Methods & clinical development

Avec: Jessica Hartmann , Frederic B Thalheimer , Felix Höpfner , Thomas Kerzel , Konstantin Khodosevich , Diego García-González , Hannah Monyer , Ilka Diester , Hildegard Büning , Jan E Carette , Pascal Fries , Christian J Buchholz

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity.

Cell reports

Avec: Jennifer Yinuo Cao , Aunoy Poddar , Leslie Magtanong , Jennifer H Lumb , Trevor R Mileur , Michael A Reid , Cole M Dovey , Jin Wang , Jason W Locasale , Everett Stone , Susan P C Cole , Jan E Carette , Scott J Dixon

Science translational medicine

Avec: Lauren E Surface , Damon T Burrow , Jinmei Li , Jiwoong Park , Sandeep Kumar , Cheng Lyu , Niki Song , Zhou Yu , Abbhirami Rajagopal , Yangjin Bae , Brendan H Lee , Steven Mumm , Charles C Gu , Jonathan C Baker , Mahshid Mohseni , Melissa Sum , Margaret Huskey , Shenghui Duan , Vinieth N Bijanki , Roberto Civitelli , Michael J Gardner , Chris M McAndrew , William M Ricci , Christina A Gurnett , Kathryn Diemer , Fei Wan , Christina L Costantino , Kristen M Shannon , Noopur Raje , Thomas B Dodson , Daniel A Haber , Jan E Carette , Malini Varadarajan , Thijn R Brummelkamp , Kivanc Birsoy , David M Sabatini , Gabe Haller , Timothy R Peterson

A memory of eS25 loss drives resistance phenotypes.

Nucleic acids research

Avec: Alex G Johnson , Ryan A Flynn , Christopher P Lapointe , Yaw Shin Ooi , Michael L Zhao , Christopher M Richards , Wenjie Qiao , Shizuka B Yamada , Julien Couthouis , Aaron D Gitler , Jan E Carette , Joseph D Puglisi

Conserved Oligomeric Golgi (COG) Complex Proteins Facilitate Orthopoxvirus Entry, Fusion and Spread.

Viruses

Avec: Susan Realegeno , Lalita Priyamvada , Amrita Kumar , Jessica B Blackburn , Claire Hartloge , Andreas S Puschnik , Suryaprakash Sambhara , Victoria A Olson , Jan E Carette , Vladimir Lupashin , Panayampalli Subbian Satheshkumar

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

Nature genetics

Avec: Scott B Biering , Sylvia A Sarnik , Eleanor Wang , James R Zengel , Sarah R Leist , Alexandra Schäfer , Varun Sathyan , Padraig Hawkins , Kenichi Okuda , Cyrus Tau , Aditya R Jangid , Connor V Duffy , Jin Wei , Rodney C Gilmore , Mia Madel Alfajaro , Madison S Strine , Xammy Nguyenla , Erik Van Dis , Carmelle Catamura , Livia H Yamashiro , Julia A Belk , Adam Begeman , Jessica C Stark , D Judy Shon , Douglas M Fox , Shahrzad Ezzatpour , Emily Huang , Nico Olegario , Arjun Rustagi , Allison S Volmer , Alessandra Livraghi-Butrico , Eddie Wehri , Richard R Behringer , Dong-Joo Cheon , Julia Schaletzky , Hector C Aguilar , Andreas S Puschnik , Brian Button , Benjamin A Pinsky , Catherine A Blish , Ralph S Baric , Wanda K O'Neal , Carolyn R Bertozzi , Craig B Wilen , Richard C Boucher , Jan E Carette , Sarah A Stanley , Eva Harris , Silvana Konermann , Patrick D Hsu

Autoantibodies are highly prevalent in non-SARS-CoV-2 respiratory infections and critical illness.

JCI insight

Avec: Allan Feng , Emily Y Yang , Andrew Reese Moore , Shaurya Dhingra , Sarah Esther Chang , Xihui Yin , Ruoxi Pi , Elisabeth Km Mack , Sara Völkel , Reinhard Geßner , Margrit Gündisch , Andreas Neubauer , Harald Renz , Sotirios Tsiodras , Paraskevi C Fragkou , Adijat A Asuni , Joseph E Levitt , Jennifer G Wilson , Michelle Leong , Jennifer H Lumb , Rong Mao , Kassandra Pinedo , Jonasel Roque , Christopher M Richards , Mikayla Stabile , Gayathri Swaminathan , Maria L Salagianni , Vasiliki Triantafyllia , Wilhelm Bertrams , Catherine A Blish , Jan E Carette , Jennifer Frankovich , Eric Meffre , Kari Christine Nadeau , Upinder Singh , Taia T Wang , Eline T Luning Prak , Susanne Herold , Evangelos Andreakos , Bernd Schmeck , Chrysanthi Skevaki , Angela J Rogers , Paul J Utz

Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens.

PloS one

Avec: Bhaven B Patel , Andres M Lebensohn , Ganesh V Pusapati , Jan E Carette , Julia Salzman , Rajat Rohatgi

Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation.

Nucleic acids research

Avec: Yanhua Song , Gaopeng Hou , Jonathan Diep , Yaw Shin Ooi , Natalia S Akopyants , Stephen M Beverley , Jan E Carette , Harry B Greenberg , Siyuan Ding

Loquacious modulates flaviviral RNA replication in mosquito cells.

PLoS pathogens

Avec: Shwetha Shivaprasad , Kuo-Feng Weng , Yaw Shin Ooi , Julia Belk , Jan E Carette , Ryan Flynn , Peter Sarnow

The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation.

bioRxiv : the preprint server for biology

Avec: Magda Wąhalska , Celeste Riepe , Magdalena J Ślusarz , Małgorzata Graul , Lukasz S Borowski , Wenjie Qiao , Michalina Foltynska , Jan E Carette , Krystyna Bieńkowska-Szewczyk , Roman J Szczesny , Ron R Kopito , Andrea D Lipińska

Characterization of Effect of Enterovirus D68 in 129/Sv Mice Deficient in IFN-α/β and/or IFN-γ Receptors.

Comparative medicine

Avec: Wenqi Song , Tanya Watarastaporn , Yaw Shin Ooi , Khanh Nguyen , Jeffery S Glenn , Jan E Carette , Kerriann M Casey , Claude M Nagamine

GPR108 Is a Highly Conserved AAV Entry Factor.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Amanda M Dudek , Nerea Zabaleta , Eric Zinn , Sirika Pillay , James Zengel , Caryn Porter , Jennifer Santos Franceschini , Reynette Estelien , Jan E Carette , Guo Ling Zhou , Luk H Vandenberghe

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling.

eLife

Avec: Ramin Dubey , Peter van Kerkhof , Ingrid Jordens , Tomas Malinauskas , Ganesh V Pusapati , Joseph K McKenna , Dan Li , Jan E Carette , Mitchell Ho , Christian Siebold , Madelon Maurice , Andres M Lebensohn , Rajat Rohatgi

Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus.

mBio

Avec: Jim Baggen , Hendrik Jan Thibaut , Daniel L Hurdiss , Maryam Wahedi , Caleb D Marceau , Arno L W van Vliet , Jan E Carette , Frank J M van Kuppeveld

An RNA-centric dissection of host complexes controlling flavivirus infection.

Nature microbiology

Avec: Yaw Shin Ooi , Karim Majzoub , Ryan A Flynn , Miguel A Mata , Jonathan Diep , Jason Kenichi Li , Nicholas van Buuren , Neil Rumachik , Alex G Johnson , Andreas S Puschnik , Caleb D Marceau , Luwanika Mlera , Jeffrey M Grabowski , Karla Kirkegaard , Marshall E Bloom , Peter Sarnow , Carolyn R Bertozzi , Jan E Carette

Differential and convergent utilization of autophagy components by positive-strand RNA viruses.

PLoS biology

Avec: Emma Abernathy , Roberto Mateo , Karim Majzoub , Nick van Buuren , Sara W Bird , Jan E Carette , Karla Kirkegaard

Réseau de co-auteurs

Yaw Shin Ooi 5 collaborations

Karim Majzoub 4 collaborations

Andreas S Puschnik 4 collaborations

Rajat Rohatgi 3 collaborations

Ryan A Flynn 3 collaborations

Alex G Johnson 3 collaborations

Carolyn R Bertozzi 3 collaborations

Christopher M Richards 3 collaborations

Ramin Dubey 2 collaborations

Sirika Pillay 2 collaborations

James R Zengel 2 collaborations

Jennifer H Lumb 2 collaborations

Wenjie Qiao 2 collaborations

Catherine A Blish 2 collaborations

Andres M Lebensohn 2 collaborations

Ganesh V Pusapati 2 collaborations

Jonathan Diep 2 collaborations

Peter Sarnow 2 collaborations

Caleb D Marceau 2 collaborations

Karla Kirkegaard 2 collaborations

Craig E Stivala 1 collaboration

Huy Quoc Nguyen 1 collaboration

Young-Hwa Goo 1 collaboration

Antoni Paul 1 collaboration

Barry M Trost 1 collaboration

L Zhang 1 collaboration

A Rossi 1 collaboration

L Lange 1 collaboration

N Meumann 1 collaboration

U Koitzsch 1 collaboration

K Christie 1 collaboration

M A Nesbit 1 collaboration

C B T Moore 1 collaboration

U T Hacker 1 collaboration

M Morgan 1 collaboration

D Hoffmann 1 collaboration

J Zengel 1 collaboration

J E Carette 1 collaboration

A Schambach 1 collaboration

A Salvetti 1 collaboration

M Odenthal 1 collaboration

H Büning 1 collaboration

Gustavo de Alencastro 1 collaboration

Francesco Puzzo 1 collaboration

Mara Pavel-Dinu 1 collaboration

Feijie Zhang 1 collaboration

Matthew Tiffany 1 collaboration

Hagoon Jang 1 collaboration

Adam Sheikali 1 collaboration

M Kyle Cromer 1 collaboration

Ruhikanta Meetei 1 collaboration

Matthew H Porteus 1 collaboration

Katja Pekrun 1 collaboration

Mark A Kay 1 collaboration

Christine E Peters 1 collaboration

Kayvon Pedram 1 collaboration

Stacy A Malaker 1 collaboration

Pedro J Batista 1 collaboration

Benjamin A H Smith 1 collaboration

Benson M George 1 collaboration

Peter W Villalta 1 collaboration

Ruofan Wang 1 collaboration

Camille R Simoneau 1 collaboration

Jessie Kulsuptrakul 1 collaboration

Mehdi Bouhaddou 1 collaboration

Katherine A Travisano 1 collaboration

Jennifer M Hayashi 1 collaboration

Jared Carlson-Stevermer 1 collaboration

Parinaz Fozouni 1 collaboration

Jennifer Oki 1 collaboration

Lauren Rodriguez 1 collaboration

Bastian Joehnk 1 collaboration

Keith Walcott 1 collaboration

Kevin Holden 1 collaboration

Anita Sil 1 collaboration

Nevan J Krogan 1 collaboration

Melanie Ott 1 collaboration

Jessica Hartmann 1 collaboration

Frederic B Thalheimer 1 collaboration

Felix Höpfner 1 collaboration

Thomas Kerzel 1 collaboration

Konstantin Khodosevich 1 collaboration

Diego García-González 1 collaboration

Hannah Monyer 1 collaboration

Ilka Diester 1 collaboration

Hildegard Büning 1 collaboration

Pascal Fries 1 collaboration

Christian J Buchholz 1 collaboration

Jennifer Yinuo Cao 1 collaboration

Aunoy Poddar 1 collaboration

Leslie Magtanong 1 collaboration

Trevor R Mileur 1 collaboration

Michael A Reid 1 collaboration

Cole M Dovey 1 collaboration

Jin Wang 1 collaboration

Jason W Locasale 1 collaboration

Everett Stone 1 collaboration

Susan P C Cole 1 collaboration

Scott J Dixon 1 collaboration

Lauren E Surface 1 collaboration

Damon T Burrow 1 collaboration

Jinmei Li 1 collaboration

Jiwoong Park 1 collaboration

Sandeep Kumar 1 collaboration

Cheng Lyu 1 collaboration

Niki Song 1 collaboration

Zhou Yu 1 collaboration

Abbhirami Rajagopal 1 collaboration

Yangjin Bae 1 collaboration

Brendan H Lee 1 collaboration

Steven Mumm 1 collaboration

Charles C Gu 1 collaboration

Jonathan C Baker 1 collaboration

Mahshid Mohseni 1 collaboration

Melissa Sum 1 collaboration

Margaret Huskey 1 collaboration

Shenghui Duan 1 collaboration

Vinieth N Bijanki 1 collaboration

Roberto Civitelli 1 collaboration

Michael J Gardner 1 collaboration

Chris M McAndrew 1 collaboration

William M Ricci 1 collaboration

Christina A Gurnett 1 collaboration

Kathryn Diemer 1 collaboration

Fei Wan 1 collaboration

Christina L Costantino 1 collaboration

Kristen M Shannon 1 collaboration

Noopur Raje 1 collaboration

Thomas B Dodson 1 collaboration

Daniel A Haber 1 collaboration

Malini Varadarajan 1 collaboration

Thijn R Brummelkamp 1 collaboration

Kivanc Birsoy 1 collaboration

David M Sabatini 1 collaboration

Gabe Haller 1 collaboration

Timothy R Peterson 1 collaboration

Christopher P Lapointe 1 collaboration

Michael L Zhao 1 collaboration

Shizuka B Yamada 1 collaboration

Julien Couthouis 1 collaboration

Aaron D Gitler 1 collaboration

Joseph D Puglisi 1 collaboration

Susan Realegeno 1 collaboration

Lalita Priyamvada 1 collaboration

Amrita Kumar 1 collaboration

Jessica B Blackburn 1 collaboration

Claire Hartloge 1 collaboration

Suryaprakash Sambhara 1 collaboration

Victoria A Olson 1 collaboration

Vladimir Lupashin 1 collaboration

Panayampalli Subbian Satheshkumar 1 collaboration

Scott B Biering 1 collaboration

Sylvia A Sarnik 1 collaboration

Eleanor Wang 1 collaboration

Sarah R Leist 1 collaboration

Alexandra Schäfer 1 collaboration

Varun Sathyan 1 collaboration

Padraig Hawkins 1 collaboration

Kenichi Okuda 1 collaboration

Cyrus Tau 1 collaboration

Aditya R Jangid 1 collaboration

Connor V Duffy 1 collaboration

Jin Wei 1 collaboration

Rodney C Gilmore 1 collaboration

Mia Madel Alfajaro 1 collaboration

Madison S Strine 1 collaboration

Xammy Nguyenla 1 collaboration

Erik Van Dis 1 collaboration

Carmelle Catamura 1 collaboration

Livia H Yamashiro 1 collaboration

Julia A Belk 1 collaboration

Adam Begeman 1 collaboration

Jessica C Stark 1 collaboration

D Judy Shon 1 collaboration

Douglas M Fox 1 collaboration

Shahrzad Ezzatpour 1 collaboration

Emily Huang 1 collaboration

Nico Olegario 1 collaboration

Arjun Rustagi 1 collaboration

Allison S Volmer 1 collaboration

Alessandra Livraghi-Butrico 1 collaboration

Eddie Wehri 1 collaboration

Richard R Behringer 1 collaboration

Dong-Joo Cheon 1 collaboration

Julia Schaletzky 1 collaboration

Hector C Aguilar 1 collaboration

Brian Button 1 collaboration

Benjamin A Pinsky 1 collaboration

Ralph S Baric 1 collaboration

Wanda K O'Neal 1 collaboration

Craig B Wilen 1 collaboration

Richard C Boucher 1 collaboration

Sarah A Stanley 1 collaboration

Eva Harris 1 collaboration

Silvana Konermann 1 collaboration

Patrick D Hsu 1 collaboration

Allan Feng 1 collaboration

Emily Y Yang 1 collaboration

Andrew Reese Moore 1 collaboration

Shaurya Dhingra 1 collaboration

Sarah Esther Chang 1 collaboration

Xihui Yin 1 collaboration

Ruoxi Pi 1 collaboration

Elisabeth Km Mack 1 collaboration

Sara Völkel 1 collaboration

Reinhard Geßner 1 collaboration

Margrit Gündisch 1 collaboration

Andreas Neubauer 1 collaboration

Harald Renz 1 collaboration

Sotirios Tsiodras 1 collaboration

Paraskevi C Fragkou 1 collaboration

Adijat A Asuni 1 collaboration

Joseph E Levitt 1 collaboration

Jennifer G Wilson 1 collaboration

Michelle Leong 1 collaboration

Rong Mao 1 collaboration

Kassandra Pinedo 1 collaboration

Jonasel Roque 1 collaboration

Mikayla Stabile 1 collaboration

Gayathri Swaminathan 1 collaboration

Maria L Salagianni 1 collaboration

Vasiliki Triantafyllia 1 collaboration

Wilhelm Bertrams 1 collaboration

Jennifer Frankovich 1 collaboration

Eric Meffre 1 collaboration

Kari Christine Nadeau 1 collaboration

Upinder Singh 1 collaboration

Taia T Wang 1 collaboration

Eline T Luning Prak 1 collaboration

Susanne Herold 1 collaboration

Evangelos Andreakos 1 collaboration

Bernd Schmeck 1 collaboration

Chrysanthi Skevaki 1 collaboration

Angela J Rogers 1 collaboration

Paul J Utz 1 collaboration

Bhaven B Patel 1 collaboration

Julia Salzman 1 collaboration

Yanhua Song 1 collaboration

Gaopeng Hou 1 collaboration

Natalia S Akopyants 1 collaboration

Stephen M Beverley 1 collaboration

Harry B Greenberg 1 collaboration

Siyuan Ding 1 collaboration

Shwetha Shivaprasad 1 collaboration

Kuo-Feng Weng 1 collaboration

Julia Belk 1 collaboration

Ryan Flynn 1 collaboration

Magda Wąhalska 1 collaboration

Celeste Riepe 1 collaboration

Magdalena J Ślusarz 1 collaboration

Małgorzata Graul 1 collaboration

Lukasz S Borowski 1 collaboration

Michalina Foltynska 1 collaboration

Krystyna Bieńkowska-Szewczyk 1 collaboration

Roman J Szczesny 1 collaboration

Ron R Kopito 1 collaboration

Andrea D Lipińska 1 collaboration

Wenqi Song 1 collaboration

Tanya Watarastaporn 1 collaboration

Khanh Nguyen 1 collaboration

Jeffery S Glenn 1 collaboration

Kerriann M Casey 1 collaboration

Claude M Nagamine 1 collaboration

Amanda M Dudek 1 collaboration

Nerea Zabaleta 1 collaboration

Eric Zinn 1 collaboration

James Zengel 1 collaboration

Caryn Porter 1 collaboration

Jennifer Santos Franceschini 1 collaboration

Reynette Estelien 1 collaboration

Guo Ling Zhou 1 collaboration

Luk H Vandenberghe 1 collaboration

Peter van Kerkhof 1 collaboration

Ingrid Jordens 1 collaboration

Tomas Malinauskas 1 collaboration

Joseph K McKenna 1 collaboration

Dan Li 1 collaboration

Mitchell Ho 1 collaboration

Christian Siebold 1 collaboration

Madelon Maurice 1 collaboration

Jim Baggen 1 collaboration

Hendrik Jan Thibaut 1 collaboration

Daniel L Hurdiss 1 collaboration

Maryam Wahedi 1 collaboration

Arno L W van Vliet 1 collaboration

Frank J M van Kuppeveld 1 collaboration

Miguel A Mata 1 collaboration

Jason Kenichi Li 1 collaboration

Nicholas van Buuren 1 collaboration

Neil Rumachik 1 collaboration

Luwanika Mlera 1 collaboration

Jeffrey M Grabowski 1 collaboration

Marshall E Bloom 1 collaboration

Emma Abernathy 1 collaboration

Roberto Mateo 1 collaboration

Nick van Buuren 1 collaboration

Sara W Bird 1 collaboration