Janneke N Samsom

Affiliations

Laboratory of Pediatrics, Division Gastroenterology and Nutrition, Erasmus University Medical Center, Rotterdam, The Netherlands.

Publications (24)

IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4

Mucosal immunology

Avec: S Veenbergen , P Li , H C Raatgeep , D J Lindenbergh-Kortleve , Y Simons-Oosterhuis , A Farrel , L M M Costes , M E Joosse , L A van Berkel , L F de Ruiter , M A van Leeuwen , D Winter , S M Holland , A F Freeman , Y Wakabayashi , J Zhu , L de Ridder , G J Driessen , J C Escher , W J Leonard , J N Samsom

Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.

Oncoimmunology

Avec: Sandrine Nugteren , Jeroen A C M Goos , Pien M Delis-van Diemen , Ytje Simons-Oosterhuis , Dicky J Lindenbergh-Kortleve , Daniëlle H van Haaften , Joyce Sanders , Gerrit A Meijer , Remond J A Fijneman , Janneke N Samsom

The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease.

Journal of Crohn's & colitis

Avec: Arno R Bourgonje , Shixian Hu , Lieke M Spekhorst , Daria V Zhernakova , Arnau Vich Vila , Yanni Li , Michiel D Voskuil , Lisette A van Berkel , Brenda Bley Folly , Mohammed Charrout , Ahmed Mahfouz , Marcel J T Reinders , Julia I P van Heck , Leo A B Joosten , Marijn C Visschedijk , Hendrik M van Dullemen , Klaas Nico Faber , Janneke N Samsom , Eleonora A M Festen , Gerard Dijkstra , Rinse K Weersma

Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis.

Mucosal immunology

Avec: Maria E Joosse , Fabienne Charbit-Henrion , Remy Boisgard , Rolien H C Raatgeep , Dicky J Lindenbergh-Kortleve , Léa M M Costes , Sandrine Nugteren , Nicolas Guegan , Marianna Parlato , Sharon Veenbergen , Valérie Malan , Jan K Nowak , Iris H I M Hollink , M Luisa Mearin , Johanna C Escher , Nadine Cerf-Bensussan , Janneke N Samsom

Long-Term Dietary Patterns Are Reflected in the Plasma Inflammatory Proteome of Patients with Inflammatory Bowel Disease.

Nutrients

Avec: Arno R Bourgonje , Laura A Bolte , Lianne L C Vranckx , Lieke M Spekhorst , Ranko Gacesa , Shixian Hu , Hendrik M van Dullemen , Marijn C Visschedijk , Eleonora A M Festen , Janneke N Samsom , Gerard Dijkstra , Rinse K Weersma , Marjo J E Campmans-Kuijpers

Endogenous secretory leukocyte protease inhibitor inhibits microbial-induced monocyte activation.

European journal of immunology

Avec: Sandrine Nugteren , Ytje Simons-Oosterhuis , Celia L Menckeberg , Danielle H Hulleman-van Haaften , Dicky J Lindenbergh-Kortleve , Janneke N Samsom

Combined plasma protein and Tmem profiling discern IBD-patient-immunotypes related to intestinal disease and treatment outcomes: Short title: Defining immunotypes in CD and UC.

Mucosal immunology

Avec: Maud Heredia , Mohammed Charrout , Renz C W Klomberg , Martine A Aardoom , Maria M E Jongsma , Polychronis Kemos , Danielle H Hulleman-van Haaften , Bastiaan Tuk , Lisette A van Berkel , Brenda Bley Folly , Beatriz Calado , Sandrine Nugteren , Ytje Simons-Oosterhuis , Michail Doukas , Mathijs A Sanders , Gregory van Beek , Frank M Ruemmele , Nicholas M Croft , Ahmed Mahfouz , Marcel J T Reinders , Johanna C Escher , Lissy de Ridder , Janneke N Samsom

Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells.

Cell reports

Avec: Mónica Romera-Hernández , Patricia Aparicio-Domingo , Natalie Papazian , Julien J Karrich , Ferry Cornelissen , Remco M Hoogenboezem , Janneke N Samsom , Tom Cupedo

IL-10 signaling prevents gluten-dependent intraepithelial CD4

Mucosal immunology

Avec: L M M Costes , D J Lindenbergh-Kortleve , L A van Berkel , S Veenbergen , H R C Raatgeep , Y Simons-Oosterhuis , D H van Haaften , J J Karrich , J C Escher , M Groeneweg , B E Clausen , T Cupedo , J N Samsom

Secretory Leukocyte Protease Inhibitor (SLPI) in mucosal tissues: Protects against inflammation, but promotes cancer.

Cytokine & growth factor reviews

Avec: Sandrine Nugteren , Janneke N Samsom

First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn's disease: an open-label multicentre randomised controlled trial.

Gut

Avec: Maria M E Jongsma , Martine A Aardoom , Martinus A Cozijnsen , Merel van Pieterson , Tim de Meij , Michael Groeneweg , Obbe F Norbruis , Victorien M Wolters , Herbert M van Wering , Iva Hojsak , Kaija-Leena Kolho , Thalia Hummel , Janneke Stapelbroek , Cathelijne van der Feen , Patrick F van Rheenen , Michiel P van Wijk , Sarah T A Teklenburg-Roord , Marco W J Schreurs , Dimitris Rizopoulos , Michail Doukas , Johanna C Escher , Janneke N Samsom , Lissy de Ridder

Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cells.

Cell reports

Avec: Justin Jacobse , Rachel E Brown , Jing Li , Jennifer M Pilat , Ly Pham , Sarah P Short , Christopher T Peek , Andrea Rolong , M Kay Washington , Ruben Martinez-Barricarte , Mariana X Byndloss , Catherine Shelton , Janet G Markle , Yvonne L Latour , Margaret M Allaman , James E Cassat , Keith T Wilson , Yash A Choksi , Christopher S Williams , Ken S Lau , Charles R Flynn , Jean-Laurent Casanova , Edmond H H M Rings , Janneke N Samsom , Jeremy A Goettel

Serum Immune Profiling in Paediatric Crohn's Disease Demonstrates Stronger Immune Modulation With First-Line Infliximab Than Conventional Therapy and Pre-Treatment Profiles Predict Clinical Response to Both Treatments.

Journal of Crohn's & colitis

Avec: Maria M E Jongsma , Lea M M Costes , Irma Tindemans , Martinus A Cozijnsen , Rolien H C Raatgreep , Merel van Pieterson , Yunlei Li , Johanna C Escher , Lissy de Ridder , Janneke N Samsom

International prospective observational study investigating the disease course and heterogeneity of paediatric-onset inflammatory bowel disease: the protocol of the PIBD-SETQuality inception cohort study.

BMJ open

Avec: Martine A Aardoom , Polychronis Kemos , Irma Tindemans , Marina Aloi , Sibylle Koletzko , Arie Levine , Dan Turner , Gigi Veereman , Mattias Neyt , Richard K Russell , Thomas D Walters , Frank M Ruemmele , Janneke N Samsom , Nicholas M Croft , Lissy de Ridder , Auteur inconnu

Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells.

European journal of immunology

Avec: Julien J Karrich , Mónica Romera-Hernández , Natalie Papazian , Sharon Veenbergen , Ferry Cornelissen , Patricia Aparicio-Domingo , Frances H Stenhouse , C Diana Peddie , Remco M Hoogenboezem , Chelsea W J den Hollander , Terri Gaskell , Tanya Medley , Louis Boon , C Clare Blackburn , David R Withers , Janneke N Samsom , Tom Cupedo

Intestinal Regulatory T Cells as Specialized Tissue-Restricted Immune Cells in Intestinal Immune Homeostasis and Disease.

Frontiers in immunology

Avec: Justin Jacobse , Jing Li , Edmond H H M Rings , Janneke N Samsom , Jeremy A Goettel

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

Scientific reports

Avec: Sandrine Nugteren , Sjoerd H den Uil , Pien M Delis-van Diemen , Ytje Simons-Oosterhuis , Dicky J Lindenbergh-Kortleve , Daniëlle H van Haaften , Hein B A C Stockmann , Joyce Sanders , Gerrit A Meijer , Remond J A Fijneman , Janneke N Samsom

Management of Autoimmune Encephalitis in a 7-Year-Old Child With CTLA-4 Haploinsufficiency and AMPA Receptor Antibodies: A Case Report.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Marjolijn S W Quaak , Michiel S J S Buijze , Virginie J M Verhoeven , Clementien Vermont , Emmeline P Buddingh , Maud Heredia , Janneke N Samsom , Maarten J Titulaer , Annemarie M van Rossum , Sylvia Kamphuis , Rinze F Neuteboom

A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization.

Clinical pharmacology and therapeutics

Avec: Kit Wun Kathy Cheung , Bianca D van Groen , Edwin Spaans , Marjolein D van Borselen , Adrianus C J M de Bruijn , Ytje Simons-Oosterhuis , Dick Tibboel , Janneke N Samsom , Robert M Verdijk , Bart Smeets , Lei Zhang , Shiew-Mei Huang , Kathleen M Giacomini , Saskia N de Wildt

Frequencies of circulating regulatory TIGIT

Mucosal immunology

Avec: Maria E Joosse , Celia L Menckeberg , Lilian F de Ruiter , H Rolien C Raatgeep , Lisette A van Berkel , Ytje Simons-Oosterhuis , Irma Tindemans , A Femke M Muskens , Rudi W Hendriks , Remco M Hoogenboezem , Tom Cupedo , Lissy de Ridder , Johanna C Escher , Sharon Veenbergen , Janneke N Samsom

Dissecting the Heterogeneity in T-Cell Mediated Inflammation in IBD.

Cells

Avec: Irma Tindemans , Maria E Joosse , Janneke N Samsom

PolyI:C Maternal Immune Activation on E9.5 Causes the Deregulation of Microglia and the Complement System in Mice, Leading to Decreased Synaptic Spine Density.

International journal of molecular sciences

Avec: Shuxin Yan , Le Wang , James Nicholas Samsom , Daniel Ujic , Fang Liu

Proteomic analyses do not reveal subclinical inflammation in fatigued patients with clinically quiescent inflammatory bowel disease.

Scientific reports

Avec: Arno R Bourgonje , Sietse J Wichers , Shixian Hu , Hendrik M van Dullemen , Marijn C Visschedijk , Klaas Nico Faber , Eleonora A M Festen , Gerard Dijkstra , Janneke N Samsom , Rinse K Weersma , Lieke M Spekhorst

Tipping the balance: inhibitory checkpoints in intestinal homeostasis.

Mucosal immunology

Avec: Maria E Joosse , Iris Nederlof , Lucy S K Walker , Janneke N Samsom

Réseau de co-auteurs

Sandrine Nugteren 6 collaborations

Ytje Simons-Oosterhuis 6 collaborations

Johanna C Escher 5 collaborations

Lissy de Ridder 5 collaborations

Dicky J Lindenbergh-Kortleve 4 collaborations

Maria E Joosse 4 collaborations

Irma Tindemans 4 collaborations

Arno R Bourgonje 3 collaborations

Shixian Hu 3 collaborations

Lieke M Spekhorst 3 collaborations

Lisette A van Berkel 3 collaborations

Marijn C Visschedijk 3 collaborations

Hendrik M van Dullemen 3 collaborations

Eleonora A M Festen 3 collaborations

Gerard Dijkstra 3 collaborations

Rinse K Weersma 3 collaborations

Sharon Veenbergen 3 collaborations

Martine A Aardoom 3 collaborations

Maria M E Jongsma 3 collaborations

Remco M Hoogenboezem 3 collaborations

Tom Cupedo 3 collaborations

S Veenbergen 2 collaborations

D J Lindenbergh-Kortleve 2 collaborations

Y Simons-Oosterhuis 2 collaborations

L M M Costes 2 collaborations

L A van Berkel 2 collaborations

J C Escher 2 collaborations

J N Samsom 2 collaborations

Pien M Delis-van Diemen 2 collaborations

Daniëlle H van Haaften 2 collaborations

Joyce Sanders 2 collaborations

Gerrit A Meijer 2 collaborations

Remond J A Fijneman 2 collaborations

Brenda Bley Folly 2 collaborations

Mohammed Charrout 2 collaborations

Ahmed Mahfouz 2 collaborations

Marcel J T Reinders 2 collaborations

Klaas Nico Faber 2 collaborations

Celia L Menckeberg 2 collaborations

Danielle H Hulleman-van Haaften 2 collaborations

Maud Heredia 2 collaborations

Polychronis Kemos 2 collaborations

Michail Doukas 2 collaborations

Frank M Ruemmele 2 collaborations

Nicholas M Croft 2 collaborations

Mónica Romera-Hernández 2 collaborations

Patricia Aparicio-Domingo 2 collaborations

Natalie Papazian 2 collaborations

Julien J Karrich 2 collaborations

Ferry Cornelissen 2 collaborations

Martinus A Cozijnsen 2 collaborations

Merel van Pieterson 2 collaborations

Justin Jacobse 2 collaborations

Jing Li 2 collaborations

Edmond H H M Rings 2 collaborations

Jeremy A Goettel 2 collaborations

P Li 1 collaboration

H C Raatgeep 1 collaboration

A Farrel 1 collaboration

M E Joosse 1 collaboration

L F de Ruiter 1 collaboration

M A van Leeuwen 1 collaboration

D Winter 1 collaboration

S M Holland 1 collaboration

A F Freeman 1 collaboration

Y Wakabayashi 1 collaboration

J Zhu 1 collaboration

L de Ridder 1 collaboration

G J Driessen 1 collaboration

W J Leonard 1 collaboration

Jeroen A C M Goos 1 collaboration

Daria V Zhernakova 1 collaboration

Arnau Vich Vila 1 collaboration

Yanni Li 1 collaboration

Michiel D Voskuil 1 collaboration

Julia I P van Heck 1 collaboration

Leo A B Joosten 1 collaboration

Fabienne Charbit-Henrion 1 collaboration

Remy Boisgard 1 collaboration

Rolien H C Raatgeep 1 collaboration

Léa M M Costes 1 collaboration

Nicolas Guegan 1 collaboration

Marianna Parlato 1 collaboration

Valérie Malan 1 collaboration

Jan K Nowak 1 collaboration

Iris H I M Hollink 1 collaboration

M Luisa Mearin 1 collaboration

Nadine Cerf-Bensussan 1 collaboration

Laura A Bolte 1 collaboration

Lianne L C Vranckx 1 collaboration

Ranko Gacesa 1 collaboration

Marjo J E Campmans-Kuijpers 1 collaboration

Renz C W Klomberg 1 collaboration

Bastiaan Tuk 1 collaboration

Beatriz Calado 1 collaboration

Mathijs A Sanders 1 collaboration

Gregory van Beek 1 collaboration

H R C Raatgeep 1 collaboration

D H van Haaften 1 collaboration

J J Karrich 1 collaboration

M Groeneweg 1 collaboration

B E Clausen 1 collaboration

T Cupedo 1 collaboration

Tim de Meij 1 collaboration

Michael Groeneweg 1 collaboration

Obbe F Norbruis 1 collaboration

Victorien M Wolters 1 collaboration

Herbert M van Wering 1 collaboration

Iva Hojsak 1 collaboration

Kaija-Leena Kolho 1 collaboration

Thalia Hummel 1 collaboration

Janneke Stapelbroek 1 collaboration

Cathelijne van der Feen 1 collaboration

Patrick F van Rheenen 1 collaboration

Michiel P van Wijk 1 collaboration

Sarah T A Teklenburg-Roord 1 collaboration

Marco W J Schreurs 1 collaboration

Dimitris Rizopoulos 1 collaboration

Rachel E Brown 1 collaboration

Jennifer M Pilat 1 collaboration

Ly Pham 1 collaboration

Sarah P Short 1 collaboration

Christopher T Peek 1 collaboration

Andrea Rolong 1 collaboration

M Kay Washington 1 collaboration

Ruben Martinez-Barricarte 1 collaboration

Mariana X Byndloss 1 collaboration

Catherine Shelton 1 collaboration

Janet G Markle 1 collaboration

Yvonne L Latour 1 collaboration

Margaret M Allaman 1 collaboration

James E Cassat 1 collaboration

Keith T Wilson 1 collaboration

Yash A Choksi 1 collaboration

Christopher S Williams 1 collaboration

Ken S Lau 1 collaboration

Charles R Flynn 1 collaboration

Jean-Laurent Casanova 1 collaboration

Lea M M Costes 1 collaboration

Rolien H C Raatgreep 1 collaboration

Yunlei Li 1 collaboration

Marina Aloi 1 collaboration

Sibylle Koletzko 1 collaboration

Arie Levine 1 collaboration

Dan Turner 1 collaboration

Gigi Veereman 1 collaboration

Mattias Neyt 1 collaboration

Richard K Russell 1 collaboration

Thomas D Walters 1 collaboration

None None 1 collaboration

Frances H Stenhouse 1 collaboration

C Diana Peddie 1 collaboration

Chelsea W J den Hollander 1 collaboration

Terri Gaskell 1 collaboration

Tanya Medley 1 collaboration

Louis Boon 1 collaboration

C Clare Blackburn 1 collaboration

David R Withers 1 collaboration

Sjoerd H den Uil 1 collaboration

Hein B A C Stockmann 1 collaboration

Marjolijn S W Quaak 1 collaboration

Michiel S J S Buijze 1 collaboration

Virginie J M Verhoeven 1 collaboration

Clementien Vermont 1 collaboration

Emmeline P Buddingh 1 collaboration

Maarten J Titulaer 1 collaboration

Annemarie M van Rossum 1 collaboration

Sylvia Kamphuis 1 collaboration

Rinze F Neuteboom 1 collaboration

Kit Wun Kathy Cheung 1 collaboration

Bianca D van Groen 1 collaboration

Edwin Spaans 1 collaboration

Marjolein D van Borselen 1 collaboration

Adrianus C J M de Bruijn 1 collaboration

Dick Tibboel 1 collaboration

Robert M Verdijk 1 collaboration

Bart Smeets 1 collaboration

Lei Zhang 1 collaboration

Shiew-Mei Huang 1 collaboration

Kathleen M Giacomini 1 collaboration

Saskia N de Wildt 1 collaboration

Lilian F de Ruiter 1 collaboration

H Rolien C Raatgeep 1 collaboration

A Femke M Muskens 1 collaboration

Rudi W Hendriks 1 collaboration

Shuxin Yan 1 collaboration

Le Wang 1 collaboration

James Nicholas Samsom 1 collaboration

Daniel Ujic 1 collaboration

Fang Liu 1 collaboration

Sietse J Wichers 1 collaboration

Iris Nederlof 1 collaboration

Lucy S K Walker 1 collaboration