Jason P Lerch

Affiliations

Neurosciences and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada.
Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Wellcome Centre for Integrative Neuroimaging, Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.

Publications (22)

White Matter Changes Caused by Mild Traumatic Brain Injury in Mice Evaluated Using Neurite Orientation Dispersion and Density Imaging.

Journal of neurotrauma

Avec: Lisa M Gazdzinski , Miranda Mellerup , Tong Wang , Seyed Amir Ali Adel , Jason P Lerch , John G Sled , Brian J Nieman , Anne L Wheeler

Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits.

Cell reports

Avec: Renee J Tamming , Vanessa Dumeaux , Yan Jiang , Sarfraz Shafiq , Luana Langlois , Jacob Ellegood , Lily R Qiu , Jason P Lerch , Nathalie G Bérubé

Effects of Antipsychotic Medication on Brain Structure in Patients With Major Depressive Disorder and Psychotic Features: Neuroimaging Findings in the Context of a Randomized Placebo-Controlled Clinical Trial.

JAMA psychiatry

Avec: Aristotle N Voineskos , Benoit H Mulsant , Erin W Dickie , Nicholas H Neufeld , Anthony J Rothschild , Ellen M Whyte , Barnett S Meyers , George S Alexopoulos , Matthew J Hoptman , Jason P Lerch , Alastair J Flint

Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration.

Scientific reports

Avec: Elisa Guma , Jill Rocchetti , Gabriel A Devenyi , Arnaud Tanti , Axel P Mathieu , Jason P Lerch , Guillaume Elgbeili , Blandine Courcot , Naguib Mechawar , M Mallar Chakravarty , Bruno Giros

Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co-chaperone STI1.

Journal of neurochemistry

Avec: Rachel E Lackie , Abdul R Razzaq , Sali M K Farhan , Lily R Qiu , Gilli Moshitzky , Flavio H Beraldo , Marilene H Lopes , Andrzej Maciejewski , Robert Gros , Jue Fan , Wing-Yiu Choy , David S Greenberg , Vilma R Martins , Martin L Duennwald , Jason P Lerch , Hermona Soreq , Vania F Prado , Marco A M Prado

Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling.

Molecular psychiatry

Avec: Melanie Richter , Nadeem Murtaza , Robin Scharrenberg , Sean H White , Ole Johanns , Susan Walker , Ryan K C Yuen , Birgit Schwanke , Bianca Bedürftig , Melad Henis , Sarah Scharf , Vanessa Kraus , Ronja Dörk , Jakob Hellmann , Zsuzsa Lindenmaier , Jacob Ellegood , Henrike Hartung , Vickie Kwan , Jan Sedlacik , Jens Fiehler , Michaela Schweizer , Jason P Lerch , Ileana L Hanganu-Opatz , Fabio Morellini , Stephen W Scherer , Karun K Singh , Froylan Calderon de Anda

Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis.

NeuroImage

Avec: Joanes Grandjean , Carola Canella , Cynthia Anckaerts , Gülebru Ayrancı , Salma Bougacha , Thomas Bienert , David Buehlmann , Ludovico Coletta , Daniel Gallino , Natalia Gass , Clément M Garin , Nachiket Abhay Nadkarni , Neele S Hübner , Meltem Karatas , Yuji Komaki , Silke Kreitz , Francesca Mandino , Anna E Mechling , Chika Sato , Katja Sauer , Disha Shah , Sandra Strobelt , Norio Takata , Isabel Wank , Tong Wu , Noriaki Yahata , Ling Yun Yeow , Yohan Yee , Ichio Aoki , M Mallar Chakravarty , Wei-Tang Chang , Marc Dhenain , Dominik von Elverfeldt , Laura-Adela Harsan , Andreas Hess , Tianzi Jiang , Georgios A Keliris , Jason P Lerch , Andreas Meyer-Lindenberg , Hideyuki Okano , Markus Rudin , Alexander Sartorius , Annemie Van der Linden , Marleen Verhoye , Wolfgang Weber-Fahr , Nicole Wenderoth , Valerio Zerbi , Alessandro Gozzi

Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling.

Molecular psychiatry

Avec: Megha Amar , Akula Bala Pramod , Nam-Kyung Yu , Victor Munive Herrera , Lily R Qiu , Patricia Moran-Losada , Pan Zhang , Cleber A Trujillo , Jacob Ellegood , Jorge Urresti , Kevin Chau , Jolene Diedrich , Jiaye Chen , Jessica Gutierrez , Jonathan Sebat , Dhakshin Ramanathan , Jason P Lerch , John R Yates , Alysson R Muotri , Lilia M Iakoucheva

Excessive Laughter-like Vocalizations, Microcephaly, and Translational Outcomes in the

The Journal of neuroscience : the official journal of the Society for Neuroscience

Avec: Elizabeth L Berg , Shekib A Jami , Stela P Petkova , Annuska Berz , Timothy A Fenton , Jason P Lerch , David J Segal , John A Gray , Jacob Ellegood , Markus Wöhr , Jill L Silverman

Pten haploinsufficiency disrupts scaling across brain areas during development in mice.

Translational psychiatry

Avec: Amy E Clipperton-Allen , Ori S Cohen , Massimiliano Aceti , Aya Zucca , Jenna Levy , Jacob Ellegood , Jason P Lerch , Damon T Page

Do shapes have feelings? Social attribution in children with autism spectrum disorder and attention-deficit/hyperactivity disorder.

Translational psychiatry

Avec: Marlee M Vandewouw , Kristina Safar , Sarah I Mossad , Julie Lu , Jason P Lerch , Evdokia Anagnostou , Margot J Taylor

Examining the Boundary Sharpness Coefficient as an Index of Cortical Microstructure in Autism Spectrum Disorder.

Cerebral cortex (New York, N.Y. : 1991)

Avec: Emily Olafson , Saashi A Bedford , Gabriel A Devenyi , Raihaan Patel , Stephanie Tullo , Min Tae M Park , Olivier Parent , Evdokia Anagnostou , Simon Baron-Cohen , Edward T Bullmore , Lindsay R Chura , Michael C Craig , Christine Ecker , Dorothea L Floris , Rosemary J Holt , Rhoshel Lenroot , Jason P Lerch , Michael V Lombardo , Declan G M Murphy , Armin Raznahan , Amber N V Ruigrok , Michael D Spencer , John Suckling , Margot J Taylor , Auteur inconnu , Meng-Chuan Lai , M Mallar Chakravarty

Transgenic mice with an R342X mutation in Phf6 display clinical features of Börjeson-Forssman-Lehmann Syndrome.

Human molecular genetics

Avec: Raies Ahmed , Shihab Sarwar , Jinghua Hu , Valérie Cardin , Lily R Qiu , Gerardo Zapata , Lucianne Vandeleur , Keqin Yan , Jason P Lerch , Mark A Corbett , Jozef Gecz , David J Picketts

Neuroanatomy and behavior in mice with a haploinsufficiency of AT-rich interactive domain 1B (ARID1B) throughout development.

Molecular autism

Avec: J Ellegood , S P Petkova , A Kinman , L R Qiu , A Adhikari , A A Wade , D Fernandes , Z Lindenmaier , A Creighton , L M J Nutter , A S Nord , J L Silverman , J P Lerch

Characterization of mice bearing humanized androgen receptor genes (h/mAr) varying in polymorphism length.

NeuroImage

Avec: Zsuzsa Lindenmaier , Yohan Yee , Adrienne Kinman , Darren Fernandes , Jacob Ellegood , Christie L Burton , Diane M Robins , Armin Raznahan , Paul Arnold , Jason P Lerch

Cortico-amygdalar connectivity and externalizing/internalizing behavior in children with neurodevelopmental disorders.

Brain structure & function

Avec: Hajer Nakua , Colin Hawco , Natalie J Forde , Grace R Jacobs , Michael Joseph , Aristotle N Voineskos , Anne L Wheeler , Meng-Chuan Lai , Peter Szatmari , Elizabeth Kelley , Xudong Liu , Stelios Georgiades , Rob Nicolson , Russell Schachar , Jennifer Crosbie , Evdokia Anagnostou , Jason P Lerch , Paul D Arnold , Stephanie H Ameis

Genetic mouse models of autism spectrum disorder present subtle heterogenous cardiac abnormalities.

Autism research : official journal of the International Society for Autism Research

Avec: Stephania Assimopoulos , Christopher Hammill , Darren J Fernandes , Tara Leigh Spencer Noakes , Yu-Qing Zhou , Lauryl M J Nutter , Jacob Ellegood , Evdokia Anagnostou , John G Sled , Jason P Lerch

A unique cerebellar pattern of microglia activation in a mouse model of encephalopathy of prematurity.

Glia

Avec: Luisa Klein , Juliette Van Steenwinckel , Bobbi Fleiss , Till Scheuer , Christoph Bührer , Valerie Faivre , Sophie Lemoine , Corinne Blugeon , Leslie Schwendimann , Zsolt Csaba , Cindy Bokobza , Dulcie A Vousden , Jason P Lerch , Anthony C Vernon , Pierre Gressens , Thomas Schmitz

Multiple-mouse magnetic resonance imaging with cryogenic radiofrequency probes for evaluation of brain development.

NeuroImage

Avec: A Arbabi , L Spencer Noakes , D Vousden , J Dazai , S Spring , O Botelho , T Keshavarzian , M Mattingly , J E Ellegood , L M J Nutter , R Wissmann , J G Sled , J P Lerch , R M Henkelman , B J Nieman

A ketogenic diet affects brain volume and metabolome in juvenile mice.

NeuroImage

Avec: Shyamchand Mayengbam , Jacob Ellegood , Mitch Kesler , Raylene A Reimer , Jane Shearer , Kartikeya Murari , Jong M Rho , Jason P Lerch , Ning Cheng

Cortical Gyrification Morphology in ASD and ADHD: Implication for Further Similarities or Disorder-Specific Features?

Cerebral cortex (New York, N.Y. : 1991)

Avec: Avideh Gharehgazlou , Marlee Vandewouw , Justine Ziolkowski , Jimmy Wong , Jennifer Crosbie , Russell Schachar , Rob Nicolson , Stelios Georgiades , Elizabeth Kelley , Muhammad Ayub , Christopher Hammill , Stephanie H Ameis , Margot J Taylor , Jason P Lerch , Evdokia Anagnostou

Exercise promotes growth and rescues volume deficits in the hippocampus after cranial radiation in young mice.

NMR in biomedicine

Avec: Kamila Szulc-Lerch , Jonas Yeung , A Elizabeth de Guzman , Shannon Egan , Yohan Yee , Darren Fernandes , Jason P Lerch , Donald J Mabbott , Brian J Nieman

Réseau de co-auteurs

Jacob Ellegood 8 collaborations

Evdokia Anagnostou 5 collaborations

Lily R Qiu 4 collaborations

M Mallar Chakravarty 3 collaborations

Yohan Yee 3 collaborations

Margot J Taylor 3 collaborations

John G Sled 2 collaborations

Brian J Nieman 2 collaborations

Anne L Wheeler 2 collaborations

Aristotle N Voineskos 2 collaborations

Gabriel A Devenyi 2 collaborations

Zsuzsa Lindenmaier 2 collaborations

Armin Raznahan 2 collaborations

Meng-Chuan Lai 2 collaborations

L M J Nutter 2 collaborations

J P Lerch 2 collaborations

Darren Fernandes 2 collaborations

Elizabeth Kelley 2 collaborations

Stelios Georgiades 2 collaborations

Rob Nicolson 2 collaborations

Russell Schachar 2 collaborations

Jennifer Crosbie 2 collaborations

Stephanie H Ameis 2 collaborations

Christopher Hammill 2 collaborations

Lisa M Gazdzinski 1 collaboration

Miranda Mellerup 1 collaboration

Tong Wang 1 collaboration

Seyed Amir Ali Adel 1 collaboration

Renee J Tamming 1 collaboration

Vanessa Dumeaux 1 collaboration

Yan Jiang 1 collaboration

Sarfraz Shafiq 1 collaboration

Luana Langlois 1 collaboration

Nathalie G Bérubé 1 collaboration

Benoit H Mulsant 1 collaboration

Erin W Dickie 1 collaboration

Nicholas H Neufeld 1 collaboration

Anthony J Rothschild 1 collaboration

Ellen M Whyte 1 collaboration

Barnett S Meyers 1 collaboration

George S Alexopoulos 1 collaboration

Matthew J Hoptman 1 collaboration

Alastair J Flint 1 collaboration

Elisa Guma 1 collaboration

Jill Rocchetti 1 collaboration

Arnaud Tanti 1 collaboration

Axel P Mathieu 1 collaboration

Guillaume Elgbeili 1 collaboration

Blandine Courcot 1 collaboration

Naguib Mechawar 1 collaboration

Bruno Giros 1 collaboration

Rachel E Lackie 1 collaboration

Abdul R Razzaq 1 collaboration

Sali M K Farhan 1 collaboration

Gilli Moshitzky 1 collaboration

Flavio H Beraldo 1 collaboration

Marilene H Lopes 1 collaboration

Andrzej Maciejewski 1 collaboration

Robert Gros 1 collaboration

Jue Fan 1 collaboration

Wing-Yiu Choy 1 collaboration

David S Greenberg 1 collaboration

Vilma R Martins 1 collaboration

Martin L Duennwald 1 collaboration

Hermona Soreq 1 collaboration

Vania F Prado 1 collaboration

Marco A M Prado 1 collaboration

Melanie Richter 1 collaboration

Nadeem Murtaza 1 collaboration

Robin Scharrenberg 1 collaboration

Sean H White 1 collaboration

Ole Johanns 1 collaboration

Susan Walker 1 collaboration

Ryan K C Yuen 1 collaboration

Birgit Schwanke 1 collaboration

Bianca Bedürftig 1 collaboration

Melad Henis 1 collaboration

Sarah Scharf 1 collaboration

Vanessa Kraus 1 collaboration

Ronja Dörk 1 collaboration

Jakob Hellmann 1 collaboration

Henrike Hartung 1 collaboration

Vickie Kwan 1 collaboration

Jan Sedlacik 1 collaboration

Jens Fiehler 1 collaboration

Michaela Schweizer 1 collaboration

Ileana L Hanganu-Opatz 1 collaboration

Fabio Morellini 1 collaboration

Stephen W Scherer 1 collaboration

Karun K Singh 1 collaboration

Froylan Calderon de Anda 1 collaboration

Joanes Grandjean 1 collaboration

Carola Canella 1 collaboration

Cynthia Anckaerts 1 collaboration

Gülebru Ayrancı 1 collaboration

Salma Bougacha 1 collaboration

Thomas Bienert 1 collaboration

David Buehlmann 1 collaboration

Ludovico Coletta 1 collaboration

Daniel Gallino 1 collaboration

Natalia Gass 1 collaboration

Clément M Garin 1 collaboration

Nachiket Abhay Nadkarni 1 collaboration

Neele S Hübner 1 collaboration

Meltem Karatas 1 collaboration

Yuji Komaki 1 collaboration

Silke Kreitz 1 collaboration

Francesca Mandino 1 collaboration

Anna E Mechling 1 collaboration

Chika Sato 1 collaboration

Katja Sauer 1 collaboration

Disha Shah 1 collaboration

Sandra Strobelt 1 collaboration

Norio Takata 1 collaboration

Isabel Wank 1 collaboration

Tong Wu 1 collaboration

Noriaki Yahata 1 collaboration

Ling Yun Yeow 1 collaboration

Ichio Aoki 1 collaboration

Wei-Tang Chang 1 collaboration

Marc Dhenain 1 collaboration

Dominik von Elverfeldt 1 collaboration

Laura-Adela Harsan 1 collaboration

Andreas Hess 1 collaboration

Tianzi Jiang 1 collaboration

Georgios A Keliris 1 collaboration

Andreas Meyer-Lindenberg 1 collaboration

Hideyuki Okano 1 collaboration

Markus Rudin 1 collaboration

Alexander Sartorius 1 collaboration

Annemie Van der Linden 1 collaboration

Marleen Verhoye 1 collaboration

Wolfgang Weber-Fahr 1 collaboration

Nicole Wenderoth 1 collaboration

Valerio Zerbi 1 collaboration

Alessandro Gozzi 1 collaboration

Megha Amar 1 collaboration

Akula Bala Pramod 1 collaboration

Nam-Kyung Yu 1 collaboration

Victor Munive Herrera 1 collaboration

Patricia Moran-Losada 1 collaboration

Pan Zhang 1 collaboration

Cleber A Trujillo 1 collaboration

Jorge Urresti 1 collaboration

Kevin Chau 1 collaboration

Jolene Diedrich 1 collaboration

Jiaye Chen 1 collaboration

Jessica Gutierrez 1 collaboration

Jonathan Sebat 1 collaboration

Dhakshin Ramanathan 1 collaboration

John R Yates 1 collaboration

Alysson R Muotri 1 collaboration

Lilia M Iakoucheva 1 collaboration

Elizabeth L Berg 1 collaboration

Shekib A Jami 1 collaboration

Stela P Petkova 1 collaboration

Annuska Berz 1 collaboration

Timothy A Fenton 1 collaboration

David J Segal 1 collaboration

John A Gray 1 collaboration

Markus Wöhr 1 collaboration

Jill L Silverman 1 collaboration

Amy E Clipperton-Allen 1 collaboration

Ori S Cohen 1 collaboration

Massimiliano Aceti 1 collaboration

Aya Zucca 1 collaboration

Jenna Levy 1 collaboration

Damon T Page 1 collaboration

Marlee M Vandewouw 1 collaboration

Kristina Safar 1 collaboration

Sarah I Mossad 1 collaboration

Julie Lu 1 collaboration

Emily Olafson 1 collaboration

Saashi A Bedford 1 collaboration

Raihaan Patel 1 collaboration

Stephanie Tullo 1 collaboration

Min Tae M Park 1 collaboration

Olivier Parent 1 collaboration

Simon Baron-Cohen 1 collaboration

Edward T Bullmore 1 collaboration

Lindsay R Chura 1 collaboration

Michael C Craig 1 collaboration

Christine Ecker 1 collaboration

Dorothea L Floris 1 collaboration

Rosemary J Holt 1 collaboration

Rhoshel Lenroot 1 collaboration

Michael V Lombardo 1 collaboration

Declan G M Murphy 1 collaboration

Amber N V Ruigrok 1 collaboration

Michael D Spencer 1 collaboration

John Suckling 1 collaboration

None None 1 collaboration

Raies Ahmed 1 collaboration

Shihab Sarwar 1 collaboration

Jinghua Hu 1 collaboration

Valérie Cardin 1 collaboration

Gerardo Zapata 1 collaboration

Lucianne Vandeleur 1 collaboration

Keqin Yan 1 collaboration

Mark A Corbett 1 collaboration

Jozef Gecz 1 collaboration

David J Picketts 1 collaboration

J Ellegood 1 collaboration

S P Petkova 1 collaboration

A Kinman 1 collaboration

L R Qiu 1 collaboration

A Adhikari 1 collaboration

A A Wade 1 collaboration

D Fernandes 1 collaboration

Z Lindenmaier 1 collaboration

A Creighton 1 collaboration

A S Nord 1 collaboration

J L Silverman 1 collaboration

Adrienne Kinman 1 collaboration

Christie L Burton 1 collaboration

Diane M Robins 1 collaboration

Paul Arnold 1 collaboration

Hajer Nakua 1 collaboration

Colin Hawco 1 collaboration

Natalie J Forde 1 collaboration

Grace R Jacobs 1 collaboration

Michael Joseph 1 collaboration

Peter Szatmari 1 collaboration

Xudong Liu 1 collaboration

Paul D Arnold 1 collaboration

Stephania Assimopoulos 1 collaboration

Darren J Fernandes 1 collaboration

Tara Leigh Spencer Noakes 1 collaboration

Yu-Qing Zhou 1 collaboration

Lauryl M J Nutter 1 collaboration

Luisa Klein 1 collaboration

Juliette Van Steenwinckel 1 collaboration

Bobbi Fleiss 1 collaboration

Till Scheuer 1 collaboration

Christoph Bührer 1 collaboration

Valerie Faivre 1 collaboration

Sophie Lemoine 1 collaboration

Corinne Blugeon 1 collaboration

Leslie Schwendimann 1 collaboration

Zsolt Csaba 1 collaboration

Cindy Bokobza 1 collaboration

Dulcie A Vousden 1 collaboration

Anthony C Vernon 1 collaboration

Pierre Gressens 1 collaboration

Thomas Schmitz 1 collaboration

A Arbabi 1 collaboration

L Spencer Noakes 1 collaboration

D Vousden 1 collaboration

J Dazai 1 collaboration

S Spring 1 collaboration

O Botelho 1 collaboration

T Keshavarzian 1 collaboration

M Mattingly 1 collaboration

J E Ellegood 1 collaboration

R Wissmann 1 collaboration

J G Sled 1 collaboration

R M Henkelman 1 collaboration

B J Nieman 1 collaboration

Shyamchand Mayengbam 1 collaboration

Mitch Kesler 1 collaboration

Raylene A Reimer 1 collaboration

Jane Shearer 1 collaboration

Kartikeya Murari 1 collaboration

Jong M Rho 1 collaboration

Ning Cheng 1 collaboration

Avideh Gharehgazlou 1 collaboration

Marlee Vandewouw 1 collaboration

Justine Ziolkowski 1 collaboration

Jimmy Wong 1 collaboration

Muhammad Ayub 1 collaboration

Kamila Szulc-Lerch 1 collaboration

Jonas Yeung 1 collaboration

A Elizabeth de Guzman 1 collaboration

Shannon Egan 1 collaboration

Donald J Mabbott 1 collaboration