Jules A A C Heuberger

Affiliations

Centre for Human Drug Research, Zernikedreef 8, 2333 CL Leiden, The Netherlands.

ORCID: 0000-0001-7202-5088

Publications (11)

Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders.

International journal of molecular sciences

Avec: Maurits F J M Vissers , Jules A A C Heuberger , Geert Jan Groeneveld

Dealing with doping. A plea for better science, governance and education.

British journal of clinical pharmacology

Avec: Jules A A C Heuberger , April Henning , Adam F Cohen , Bengt Kayser

Acute retigabine-induced effects on myelinated motor axons in amyotrophic lateral sclerosis.

Pharmacology research & perspectives

Avec: Boudewijn T H M Sleutjes , Diederik J L Stikvoort García , Maria O Kovalchuk , Jules A A C Heuberger , Geert Jan Groeneveld , Hessel Franssen , Leonard H van den Berg

Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double-blind placebo-controlled cross-over study.

Clinical and translational science

Avec: Titia Q Ruijs , Ingrid W Koopmans , Marieke L de Kam , Martijn R Tannemaat , Geert Jan Groeneveld , Jules A A C Heuberger

EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis.

Nature communications

Avec: Daniel Hidalgo , Jacob Bejder , Ramona Pop , Kyle Gellatly , Yung Hwang , S Maxwell Scalf , Anna E Eastman , Jane-Jane Chen , Lihua Julie Zhu , Jules A A C Heuberger , Shangqin Guo , Mark J Koury , Nikolai Baastrup Nordsborg , Merav Socolovsky

The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis.

Science translational medicine

Avec: Martin Skov , Titia Q Ruijs , Thomas S Grønnebæk , Marianne Skals , Anders Riisager , Jeppe Blichfeldt Winther , Kamilla Løhde Tordrup Dybdahl , Anders Findsen , Jeanette J Morgen , Nete Huus , Martin Broch-Lips , Ole B Nielsen , Catherine M K E de Cuba , Jules A A C Heuberger , Marieke L de Kam , Martijn Tannemaat , Jan J G M Verschuuren , Lars J S Knutsen , Nicholas M Kelly , Klaus G Jensen , William D Arnold , Arthur H Burghes , Claus Olesen , Jane Bold , Thomas K Petersen , Jorge A Quiroz , John Hutchison , Eva R Chin , Geert J Groeneveld , Thomas H Pedersen

Effects of Mexiletine and Lacosamide on Nerve Excitability in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.

Clinical pharmacology and therapeutics

Avec: Titia Q Ruijs , Ingrid W Koopmans , Marieke L de Kam , Michiel J van Esdonk , Martin Koltzenburg , Geert Jan Groeneveld , Jules A A C Heuberger

Review of WADA Prohibited Substances: Limited Evidence for Performance-Enhancing Effects.

Sports medicine (Auckland, N.Z.)

Avec: Jules A A C Heuberger , Adam F Cohen

Additive effect of erythropoietin use on exercise-induced endothelial activation and hypercoagulability in athletes.

European journal of applied physiology

Avec: Jules A A C Heuberger , Jelle J Posthuma , Dimitrios Ziagkos , Joris I Rotmans , Johannes M A Daniels , Pim Gal , Frederik E Stuurman , Henri M H Spronk , Hugo Ten Cate , Jacobus Burggraaf , Matthijs Moerland , Adam F Cohen

Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double-blind, placebo-controlled, cross-over study.

British journal of clinical pharmacology

Avec: Titia Q Ruijs , Jules A A C Heuberger , Annika A de Goede , Dimitrios Ziagkos , Marije E Otto , Robert J Doll , Michel J A M van Putten , Geert Jan Groeneveld

DNL104, a Centrally Penetrant RIPK1 Inhibitor, Inhibits RIP1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers.

Clinical pharmacology and therapeutics

Avec: Hendrika W Grievink , Jules A A C Heuberger , Fen Huang , Rinkal Chaudhary , Willem A J Birkhoff , George R Tonn , Sofia Mosesova , Rebecca Erickson , Matthijs Moerland , Patrick C G Haddick , Kimberly Scearce-Levie , Carole Ho , Geert Jan Groeneveld

Réseau de co-auteurs

Geert Jan Groeneveld 6 collaborations

Titia Q Ruijs 4 collaborations

Adam F Cohen 3 collaborations

Marieke L de Kam 3 collaborations

Ingrid W Koopmans 2 collaborations

Dimitrios Ziagkos 2 collaborations

Matthijs Moerland 2 collaborations

Maurits F J M Vissers 1 collaboration

April Henning 1 collaboration

Bengt Kayser 1 collaboration

Boudewijn T H M Sleutjes 1 collaboration

Diederik J L Stikvoort García 1 collaboration

Maria O Kovalchuk 1 collaboration

Hessel Franssen 1 collaboration

Leonard H van den Berg 1 collaboration

Martijn R Tannemaat 1 collaboration

Daniel Hidalgo 1 collaboration

Jacob Bejder 1 collaboration

Ramona Pop 1 collaboration

Kyle Gellatly 1 collaboration

Yung Hwang 1 collaboration

S Maxwell Scalf 1 collaboration

Anna E Eastman 1 collaboration

Jane-Jane Chen 1 collaboration

Lihua Julie Zhu 1 collaboration

Shangqin Guo 1 collaboration

Mark J Koury 1 collaboration

Nikolai Baastrup Nordsborg 1 collaboration

Merav Socolovsky 1 collaboration

Martin Skov 1 collaboration

Thomas S Grønnebæk 1 collaboration

Marianne Skals 1 collaboration

Anders Riisager 1 collaboration

Jeppe Blichfeldt Winther 1 collaboration

Kamilla Løhde Tordrup Dybdahl 1 collaboration

Anders Findsen 1 collaboration

Jeanette J Morgen 1 collaboration

Nete Huus 1 collaboration

Martin Broch-Lips 1 collaboration

Ole B Nielsen 1 collaboration

Catherine M K E de Cuba 1 collaboration

Martijn Tannemaat 1 collaboration

Jan J G M Verschuuren 1 collaboration

Lars J S Knutsen 1 collaboration

Nicholas M Kelly 1 collaboration

Klaus G Jensen 1 collaboration

William D Arnold 1 collaboration

Arthur H Burghes 1 collaboration

Claus Olesen 1 collaboration

Jane Bold 1 collaboration

Thomas K Petersen 1 collaboration

Jorge A Quiroz 1 collaboration

John Hutchison 1 collaboration

Eva R Chin 1 collaboration

Geert J Groeneveld 1 collaboration

Thomas H Pedersen 1 collaboration

Michiel J van Esdonk 1 collaboration

Martin Koltzenburg 1 collaboration

Jelle J Posthuma 1 collaboration

Joris I Rotmans 1 collaboration

Johannes M A Daniels 1 collaboration

Pim Gal 1 collaboration

Frederik E Stuurman 1 collaboration

Henri M H Spronk 1 collaboration

Hugo Ten Cate 1 collaboration

Jacobus Burggraaf 1 collaboration

Annika A de Goede 1 collaboration

Marije E Otto 1 collaboration

Robert J Doll 1 collaboration

Michel J A M van Putten 1 collaboration

Hendrika W Grievink 1 collaboration

Fen Huang 1 collaboration

Rinkal Chaudhary 1 collaboration

Willem A J Birkhoff 1 collaboration

George R Tonn 1 collaboration

Sofia Mosesova 1 collaboration

Rebecca Erickson 1 collaboration

Patrick C G Haddick 1 collaboration

Kimberly Scearce-Levie 1 collaboration

Carole Ho 1 collaboration