Krystian Andrezej Kozek

Affiliations

Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, USA.
Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

Publications (8)

Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) Channels.

ACS chemical neuroscience

Avec: Krystian A Kozek , Yu Du , Swagat Sharma , Francis J Prael , Brittany D Spitznagel , Sujay V Kharade , Jerod S Denton , Corey R Hopkins , C David Weaver

High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel K

Heart rhythm

Avec: Krystian A Kozek , Andrew M Glazer , Chai-Ann Ng , Daniel Blackwell , Christian L Egly , Loren R Vanags , Marcia Blair , Devyn Mitchell , Kenneth A Matreyek , Douglas M Fowler , Bjorn C Knollmann , Jamie I Vandenberg , Dan M Roden , Brett M Kroncke

Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators.

Bioorganic & medicinal chemistry letters

Avec: Swagat Sharma , Krystian A Kozek , Kristopher K Abney , Sushil Kumar , Nagsen Gautam , Yazen Alnouti , C David Weaver , Corey R Hopkins

Challenges in the Discovery and Optimization of mGlu

Letters in drug design & discovery

Avec: Mark Gallant Fulton , Matthew Thomas Loch , Caroline Anne Cuoco , Alice Lambert Rodriguez , Emily Days , Paige Newton Vinson , Krystian Andrezej Kozek , Charles David Weaver , Anna Louise Blobaum , Peter Jeffrey Conn , Colleen Marie Niswender , Craig William Lindsley

Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers.

Angewandte Chemie (International ed. in English)

Avec: Julie B Trads , Katharina Hüll , Bryan S Matsuura , Laura Laprell , Timm Fehrentz , Nicole Görldt , Krystian A Kozek , C David Weaver , Nikolaj Klöcker , David M Barber , Dirk Trauner

Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models.

ACS chemical neuroscience

Avec: Kristopher K Abney , Michael Bubser , Yu Du , Krystian A Kozek , Thomas M Bridges , Craig W Linsdley , J Scott Daniels , Ryan D Morrison , Kevin Wickman , Corey R Hopkins , Carrie K Jones , C David Weaver

VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical Neurons.

ACS chemical neuroscience

Avec: Brittany D Spitznagel , Nigam M Mishra , Alshaima'a M Qunies , Francis J Prael , Yu Du , Krystian A Kozek , Roman M Lazarenko , Jerod S Denton , Kyle A Emmitte , C David Weaver

A massively parallel assay accurately discriminates between functionally normal and abnormal variants in a hotspot domain of KCNH2.

American journal of human genetics

Avec: Chai-Ann Ng , Rizwan Ullah , Jessica Farr , Adam P Hill , Krystian A Kozek , Loren R Vanags , Devyn W Mitchell , Brett M Kroncke , Jamie I Vandenberg

Réseau de co-auteurs

Krystian A Kozek 7 collaborations

C David Weaver 5 collaborations

Yu Du 3 collaborations

Corey R Hopkins 3 collaborations

Swagat Sharma 2 collaborations

Francis J Prael 2 collaborations

Brittany D Spitznagel 2 collaborations

Jerod S Denton 2 collaborations

Chai-Ann Ng 2 collaborations

Loren R Vanags 2 collaborations

Jamie I Vandenberg 2 collaborations

Brett M Kroncke 2 collaborations

Kristopher K Abney 2 collaborations

Sujay V Kharade 1 collaboration

Andrew M Glazer 1 collaboration

Daniel Blackwell 1 collaboration

Christian L Egly 1 collaboration

Marcia Blair 1 collaboration

Devyn Mitchell 1 collaboration

Kenneth A Matreyek 1 collaboration

Douglas M Fowler 1 collaboration

Bjorn C Knollmann 1 collaboration

Dan M Roden 1 collaboration

Sushil Kumar 1 collaboration

Nagsen Gautam 1 collaboration

Yazen Alnouti 1 collaboration

Mark Gallant Fulton 1 collaboration

Matthew Thomas Loch 1 collaboration

Caroline Anne Cuoco 1 collaboration

Alice Lambert Rodriguez 1 collaboration

Emily Days 1 collaboration

Paige Newton Vinson 1 collaboration

Charles David Weaver 1 collaboration

Anna Louise Blobaum 1 collaboration

Peter Jeffrey Conn 1 collaboration

Colleen Marie Niswender 1 collaboration

Craig William Lindsley 1 collaboration

Julie B Trads 1 collaboration

Katharina Hüll 1 collaboration

Bryan S Matsuura 1 collaboration

Laura Laprell 1 collaboration

Timm Fehrentz 1 collaboration

Nicole Görldt 1 collaboration

Nikolaj Klöcker 1 collaboration

David M Barber 1 collaboration

Dirk Trauner 1 collaboration

Michael Bubser 1 collaboration

Thomas M Bridges 1 collaboration

Craig W Linsdley 1 collaboration

J Scott Daniels 1 collaboration

Ryan D Morrison 1 collaboration

Kevin Wickman 1 collaboration

Carrie K Jones 1 collaboration

Nigam M Mishra 1 collaboration

Alshaima'a M Qunies 1 collaboration

Roman M Lazarenko 1 collaboration

Kyle A Emmitte 1 collaboration

Rizwan Ullah 1 collaboration

Jessica Farr 1 collaboration

Adam P Hill 1 collaboration

Devyn W Mitchell 1 collaboration