Lars Plate

Affiliations

Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Publications (14)

Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and Blastocysts.

International journal of molecular sciences

Avec: Oktay Kirak , Eugene Ke , Kevin Y Yang , Anna Schwarz , Lars Plate , Amy Nham , Justin R Abadejos , Anna Valencia , R Luke Wiseman , Kathy O Lui , Manching Ku

Site-specific crosslinking reveals Phosphofructokinase-L inhibition drives self-assembly and attenuation of protein interactions.

Advances in biological regulation

Avec: Athira Sivadas , Eli Fritz McDonald , Sydney O Shuster , Caitlin M Davis , Lars Plate

Proteostasis Landscapes of Selective versus Poorly Responsive CFTR Variants Reveals Structural Vulnerabilities to Correction.

bioRxiv : the preprint server for biology

Avec: Eli Fritz McDonald , Minsoo Kim , John A Olson , Jens Meiler , Lars Plate

The proteostasis interactomes of trafficking-deficient variants of the voltage-gated potassium channel K

The Journal of biological chemistry

Avec: Christian L Egly , Lea A Barny , Tri Do , Eli F McDonald , Bjorn C Knollmann , Lars Plate

Revealing functional insights into ER proteostasis through proteomics and interactomics.

Experimental cell research

Avec: Madison T Wright , Lars Plate

Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants.

bioRxiv : the preprint server for biology

Avec: Eli Fritz McDonald , Kathryn E Oliver , Jonathan P Schlebach , Jens Meiler , Lars Plate

CFTR Folding: From Structure and Proteostasis to Cystic Fibrosis Personalized Medicine.

ACS chemical biology

Avec: Eli Fritz McDonald , Jens Meiler , Lars Plate

BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Dongsheng Han , Samantha H Schaffner , Jonathan P Davies , Mary Lauren Benton , Lars Plate , Jared T Nordman

Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging.

The EMBO journal

Avec: Felipe Cabral-Miranda , Giovanni Tamburini , Gabriela Martinez , Alvaro O Ardiles , Danilo B Medinas , Yannis Gerakis , Mei-Li Diaz Hung , René Vidal , Matias Fuentealba , Tim Miedema , Claudia Duran-Aniotz , Javier Diaz , Cristobal Ibaceta-Gonzalez , Carleen M Sabusap , Francisca Bermedo-Garcia , Paula Mujica , Stuart Adamson , Kaitlyn Vitangcol , Hernan Huerta , Xu Zhang , Tomohiro Nakamura , Sergio Pablo Sardi , Stuart A Lipton , Brian K Kennedy , Juan Pablo Henriquez , J Cesar Cárdenas , Lars Plate , Adrian G Palacios , Claudio Hetz

The proteostasis interactomes of trafficking-deficient K

bioRxiv : the preprint server for biology

Avec: Christian L Egly , Lea Barny , Tri Do , Eli F McDonald , Lars Plate , Bjorn C Knollmann

Ribosomal Frameshifting Selectively Modulates the Assembly, Function, and Pharmacological Rescue of a Misfolded CFTR Variant.

bioRxiv : the preprint server for biology

Avec: Patrick Carmody , Francis J Roushar , Austin Tedman , Wei Wang , Madeline Herwig , Minsoo Kim , Eli Fritz McDonald , Karen Noguera , Jennifer Wong-Roushar , Jon-Luc Poirier , Nathan Zelt , Ben Pockrass , Andrew G McKee , Charles P Kuntz , S Vamsee Raju , Lars Plate , Wesley D Penn , Jonathan P Schlebach

Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase.

Nature chemical biology

Avec: Benjamin J Reisman , Hui Guo , Haley E Ramsey , Madison T Wright , Bradley I Reinfeld , P Brent Ferrell , Gary A Sulikowski , W Kimryn Rathmell , Michael R Savona , Lars Plate , John L Rubinstein , Brian O Bachmann

Glycosylation limits forward trafficking of the tetraspan membrane protein PMP22.

The Journal of biological chemistry

Avec: Justin T Marinko , Madison T Wright , Jonathan P Schlebach , Katherine R Clowes , Darren R Heintzman , Lars Plate , Charles R Sanders

Thyroglobulin Interactome Profiling Defines Altered Proteostasis Topology Associated With Thyroid Dyshormonogenesis.

Molecular & cellular proteomics : MCP

Avec: Madison T Wright , Logan Kouba , Lars Plate

Réseau de co-auteurs

Eli Fritz McDonald 5 collaborations

Madison T Wright 4 collaborations

Jens Meiler 3 collaborations

Jonathan P Schlebach 3 collaborations

Minsoo Kim 2 collaborations

Christian L Egly 2 collaborations

Tri Do 2 collaborations

Eli F McDonald 2 collaborations

Bjorn C Knollmann 2 collaborations

Oktay Kirak 1 collaboration

Eugene Ke 1 collaboration

Kevin Y Yang 1 collaboration

Anna Schwarz 1 collaboration

Amy Nham 1 collaboration

Justin R Abadejos 1 collaboration

Anna Valencia 1 collaboration

R Luke Wiseman 1 collaboration

Kathy O Lui 1 collaboration

Manching Ku 1 collaboration

Athira Sivadas 1 collaboration

Sydney O Shuster 1 collaboration

Caitlin M Davis 1 collaboration

John A Olson 1 collaboration

Lea A Barny 1 collaboration

Kathryn E Oliver 1 collaboration

Dongsheng Han 1 collaboration

Samantha H Schaffner 1 collaboration

Jonathan P Davies 1 collaboration

Mary Lauren Benton 1 collaboration

Jared T Nordman 1 collaboration

Felipe Cabral-Miranda 1 collaboration

Giovanni Tamburini 1 collaboration

Gabriela Martinez 1 collaboration

Alvaro O Ardiles 1 collaboration

Danilo B Medinas 1 collaboration

Yannis Gerakis 1 collaboration

Mei-Li Diaz Hung 1 collaboration

René Vidal 1 collaboration

Matias Fuentealba 1 collaboration

Tim Miedema 1 collaboration

Claudia Duran-Aniotz 1 collaboration

Javier Diaz 1 collaboration

Cristobal Ibaceta-Gonzalez 1 collaboration

Carleen M Sabusap 1 collaboration

Francisca Bermedo-Garcia 1 collaboration

Paula Mujica 1 collaboration

Stuart Adamson 1 collaboration

Kaitlyn Vitangcol 1 collaboration

Hernan Huerta 1 collaboration

Xu Zhang 1 collaboration

Tomohiro Nakamura 1 collaboration

Sergio Pablo Sardi 1 collaboration

Stuart A Lipton 1 collaboration

Brian K Kennedy 1 collaboration

Juan Pablo Henriquez 1 collaboration

J Cesar Cárdenas 1 collaboration

Adrian G Palacios 1 collaboration

Claudio Hetz 1 collaboration

Lea Barny 1 collaboration

Patrick Carmody 1 collaboration

Francis J Roushar 1 collaboration

Austin Tedman 1 collaboration

Wei Wang 1 collaboration

Madeline Herwig 1 collaboration

Karen Noguera 1 collaboration

Jennifer Wong-Roushar 1 collaboration

Jon-Luc Poirier 1 collaboration

Nathan Zelt 1 collaboration

Ben Pockrass 1 collaboration

Andrew G McKee 1 collaboration

Charles P Kuntz 1 collaboration

S Vamsee Raju 1 collaboration

Wesley D Penn 1 collaboration

Benjamin J Reisman 1 collaboration

Hui Guo 1 collaboration

Haley E Ramsey 1 collaboration

Bradley I Reinfeld 1 collaboration

P Brent Ferrell 1 collaboration

Gary A Sulikowski 1 collaboration

W Kimryn Rathmell 1 collaboration

Michael R Savona 1 collaboration

John L Rubinstein 1 collaboration

Brian O Bachmann 1 collaboration

Justin T Marinko 1 collaboration

Katherine R Clowes 1 collaboration

Darren R Heintzman 1 collaboration

Charles R Sanders 1 collaboration

Logan Kouba 1 collaboration