Leonard Hofstra

Affiliations

Department of Cardiology, Amsterdam UMC VUMC Site, Amsterdam, The Netherlands leonard.hofstra@gmail.com.
Cardiology Centers of the Netherlands, Utrecht, The Netherlands.

Publications (27)

Effectiveness of web-based personalised e‑Coaching lifestyle interventions.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Avec: H Yousuf , R Reintjens , E Slipszenko , S Blok , G A Somsen , I I Tulevski , L Hofstra

Outcomes in patients with a first episode of chest pain undergoing early coronary CT imaging.

Heart (British Cardiac Society)

Avec: Klaske R Siegersma , N Charlotte Onland-Moret , Yolande Appelman , Pim van der Harst , Igor I Tulevski , G Aernout Somsen , Jagat Narula , Hester M den Ruijter , Leonard Hofstra

Coronary computed tomographic angiography as gatekeeper for new-onset stable angina.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Avec: C K M Boerhout , R G T Feenstra , G A Somsen , Y Appelman , P Ong , M A M Beijk , L Hofstra , T P van de Hoef , J J Piek

A media intervention applying debunking versus non-debunking content to combat vaccine misinformation in elderly in the Netherlands: A digital randomised trial.

EClinicalMedicine

Avec: Hamza Yousuf , Sander van der Linden , Luke Bredius , G A Ted van Essen , Govert Sweep , Zohar Preminger , Eric van Gorp , Erik Scherder , Jagat Narula , Leonard Hofstra

Deep neural networks reveal novel sex-specific electrocardiographic features relevant for mortality risk.

European heart journal. Digital health

Avec: Klaske R Siegersma , Rutger R van de Leur , N Charlotte Onland-Moret , David A Leon , Ernest Diez-Benavente , Liesbeth Rozendaal , Michiel L Bots , Ruben Coronel , Yolande Appelman , Leonard Hofstra , Pim van der Harst , Pieter A Doevendans , Rutger J Hassink , Hester M den Ruijter , René van Es

Plasma Proteomic Patterns Show Sex Differences in Early Concentric Left Ventricular Remodeling.

Circulation. Heart failure

Avec: Anne-Mar van Ommen , Ernest Diez Benavente , N Charlotte Onland-Moret , Gideon B Valstar , Maarten J Cramer , Frans H Rutten , Arco J Teske , Roxana Menken , Leonard Hofstra , Igor I Tulevski , Nancy Sweitzer , G Aernout Somsen , Hester M den Ruijter

Personalized E-Coaching in Cardiovascular Risk Reduction: A Randomized Controlled Trial.

Annals of global health

Avec: Mohammed Y Khanji , Armida Balawon , Redha Boubertakh , Leonard Hofstra , Jagat Narula , Myriam Hunink , Francesca Pugliese , Steffen E Petersen

Artificial intelligence in cardiovascular imaging: state of the art and implications for the imaging cardiologist.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Avec: K R Siegersma , T Leiner , D P Chew , Y Appelman , L Hofstra , J W Verjans

The HFA-PEFF score identifies 'early-HFpEF' phenogroups associated with distinct biomarker profiles.

ESC heart failure

Avec: Michiel T H M Henkens , Anne-Mar van Ommen , Sharon Remmelzwaal , Gideon B Valstar , Ping Wang , Job A J Verdonschot , Mark R Hazebroek , Leonard Hofstra , Vanessa P M van Empel , Joline W J Beulens , Hester M den Ruijter , Stephane R B Heymans

Current state of artificial intelligence-based algorithms for hospital admission prediction in patients with heart failure: a scoping review

European heart journal. Digital health

Avec: P M Croon , J L Selder , C P Allaart , H Bleijendaal , S A J Chamuleau , L Hofstra , I Išgum , K A Ziesemer , M M Winter

The importance of cultural tailoring of communicators and media outlets in an influenza vaccination awareness campaign: a digital randomized trial.

Scientific reports

Avec: G L Habib , H Yousuf , L Bredius , N R Bindraban , M M Winter , E J A Scherder , S van der Linden , J Narula , L Hofstra

Association of mild kidney dysfunction with diastolic dysfunction and heart failure with preserved ejection fraction.

ESC heart failure

Avec: Robin W M Vernooij , Anne-Mar L N van Ommen , Gideon B Valstar , Maarten Jan Cramer , Arco J Teske , Roxana Menken , Leo Hofstra , Frans H Rutten , Michiel L Bots , Hester M den Ruijter , Marianne C Verhaar

Association of a Public Health Campaign About Coronavirus Disease 2019 Promoted by News Media and a Social Influencer With Self-reported Personal Hygiene and Physical Distancing in the Netherlands.

JAMA network open

Avec: Hamza Yousuf , Jonathan Corbin , Govert Sweep , Martijn Hofstra , Erik Scherder , Eric van Gorp , Peter Paul Zwetsloot , Jiayu Zhao , Bert van Rossum , Ting Jiang , Jan-Willem Lindemans , Jagat Narula , Leonard Hofstra

Routine clinical care data from thirteen cardiac outpatient clinics: design of the Cardiology Centers of the Netherlands (CCN) database.

BMC cardiovascular disorders

Avec: Sophie H Bots , Klaske R Siegersma , N Charlotte Onland-Moret , Folkert W Asselbergs , G Aernout Somsen , Igor I Tulevski , Hester M den Ruijter , Leonard Hofstra

Novel advances in cardiac rehabilitation : Position paper from the Working Group on Preventive Cardiology and Cardiac Rehabilitation of the Netherlands Society of Cardiology.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Avec: T Vromen , R W M Brouwers , H T Jorstad , R A Kraaijenhagen , R F Spee , M E Wittekoek , M J Cramer , J M C van Hal , L Hofstra , P M J C Kuijpers , E C de Melker , S F Rodrigo , M Sunamura , N H M K Uszko-Lencer , H M Kemps

Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum.

Scientific reports

Avec: Karolina Andrzejczyk , Sabrina Abou Kamar , Anne-Mar van Ommen , Elisa Dal Canto , Teun B Petersen , Gideon Valstar , K Martijn Akkerhuis , Maarten Jan Cramer , Victor Umans , Frans H Rutten , Arco Teske , Eric Boersma , Roxana Menken , Bas M van Dalen , Leonard Hofstra , Marianne Verhaar , Jasper Brugts , Folkert Asselbergs , Hester den Ruijter , Isabella Kardys

Coronary artery disease prediction in women and men using chest pain characteristics and risk factors: an observational study in outpatient clinics.

BMJ open

Avec: Floor Groepenhoff , Anouk L M Eikendal , N Charlotte Onland-Moret , Sophie Heleen Bots , Roxana Menken , Igor I Tulevski , Aernout G Somsen , Leonard Hofstra , Hester M den Ruijter

Discovery of biomarkers for the presence and progression of left ventricular diastolic dysfunction and HEart faiLure with Preserved ejection Fraction in patients at risk for cardiovascular disease: rationale and design of the HELPFul case-cohort study in a Dutch cardiology outpatient clinic.

BMJ open

Avec: Gideon B Valstar , Sophie H Bots , Floor Groepenhoff , Aisha Gohar , Frans H Rutten , Tim Leiner , Maarten Jan Maria Cramer , Arco J Teske , Leonardo P Suciadi , Roxana Menken , Gerard Pasterkamp , Folkert W Asselbergs , Leonard Hofstra , Michael L Bots , Hester M den Ruijter

The cardiovascular risk profile of middle age women previously diagnosed with premature ovarian insufficiency: A case-control study.

PloS one

Avec: Marlise N Gunning , Cindy Meun , Bas B van Rijn , Nadine M P Daan , Jeanine E Roeters van Lennep , Yolande Appelman , Eric Boersma , Leonard Hofstra , Clemens G K M Fauser , Oscar L Rueda-Ochoa , Mohammad A Ikram , Maryam Kavousi , Cornelis B Lambalk , Marinus J C Eijkemans , Joop S E Laven , Bart C J M Fauser , Auteur inconnu

Estimated Worldwide Mortality Attributed to Secondhand Tobacco Smoke Exposure, 1990-2016.

JAMA network open

Avec: Hamza Yousuf , Martijn Hofstra , Jan Tijssen , Brian Leenen , Jan Willem Lindemans , Albert van Rossum , Jagat Narula , Leonard Hofstra

Cardiovascular imaging of women and men visiting the outpatient clinic with chest pain or discomfort: design and rationale of the ARGUS Study.

BMJ open

Avec: Floor Groepenhoff , Anouk L M Eikendal , Sophie Heleen Bots , Anne-Mar van Ommen , L M Overmars , Daniek Kapteijn , Gerard Pasterkamp , Johan H C Reiber , David Hautemann , Roxana Menken , Marianne E Wittekoek , Leonard Hofstra , N Charlotte Onland-Moret , Saskia Haitjema , Imo Hoefer , Tim Leiner , Hester M den Ruijter

Functional stress imaging to predict abnormal coronary fractional flow reserve: the PACIFIC 2 study.

European heart journal

Avec: Roel S Driessen , Pepijn A van Diemen , Pieter G Raijmakers , Juhani Knuuti , Teemu Maaniitty , S Richard Underwood , Eike Nagel , Lourens F H J Robbers , Ahmet Demirkiran , Martin B von Bartheld , Peter M van de Ven , Leonard Hofstra , G Aernout Somsen , Igor I Tulevski , Ronald Boellaard , Albert C van Rossum , Ibrahim Danad , Paul Knaapen

Development of a Pipeline for Adverse Drug Reaction Identification in Clinical Notes: Word Embedding Models and String Matching.

JMIR medical informatics

Avec: Klaske R Siegersma , Maxime Evers , Sophie H Bots , Floor Groepenhoff , Yolande Appelman , Leonard Hofstra , Igor I Tulevski , G Aernout Somsen , Hester M den Ruijter , Marco Spruit , N Charlotte Onland-Moret

Coronary calcification measures predict mortality in symptomatic women and men.

Open heart

Avec: Klaske R Siegersma , Floor Groepenhoff , Anouk L M Eikendal , Willemijn J Op den Brouw , Tim Leiner , Yolande Appelman , Igor I Tulevski , G Aernout Somsen , N Charlotte Onland-Moret , Leonard Hofstra , Hester M den Ruijter

Characterization of HIV variants from paired Cerebrospinal fluid and Plasma samples in primary microglia and CD4

Journal of neurovirology

Avec: Stephanie B H Gumbs , Arjen J Stam , Tania Mudrikova , Pauline J Schipper , Andy I M Hoepelman , Petra M van Ham , Anne L Borst , LMarije Hofstra , Lavina Gharu , Stephanie van Wyk , Eduan Wilkinson , Lot D de Witte , Annemarie M J Wensing , Monique Nijhuis

Sex Differences in the Relationship between New York Heart Association Functional Classification and Survival in Cardiovascular Disease Patients: A Mediation Analysis of Exercise Capacity with Regular Care Data.

Reviews in cardiovascular medicine

Avec: Klaske R Siegersma , Niels A Stens , Floor Groepenhoff , Yolande Appelman , Igor I Tulevski , Leonard Hofstra , Hester M den Ruijter , G Aernout Somsen , N Charlotte Onland-Moret

Enhancing cardiovascular artificial intelligence (AI) research in the Netherlands: CVON-AI consortium.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Avec: J W Benjamins , K van Leeuwen , L Hofstra , M Rienstra , Y Appelman , W Nijhof , B Verlaat , I Everts , H M den Ruijter , I Isgum , T Leiner , R Vliegenthart , F W Asselbergs , L E Juarez-Orozco , P van der Harst

Réseau de co-auteurs

Hester M den Ruijter 12 collaborations

N Charlotte Onland-Moret 9 collaborations

Igor I Tulevski 8 collaborations

L Hofstra 7 collaborations

G Aernout Somsen 7 collaborations

Klaske R Siegersma 6 collaborations

Yolande Appelman 6 collaborations

Roxana Menken 6 collaborations

Floor Groepenhoff 6 collaborations

Jagat Narula 5 collaborations

Anne-Mar van Ommen 4 collaborations

Gideon B Valstar 4 collaborations

Frans H Rutten 4 collaborations

Y Appelman 3 collaborations

Hamza Yousuf 3 collaborations

Arco J Teske 3 collaborations

Sophie H Bots 3 collaborations

Anouk L M Eikendal 3 collaborations

Tim Leiner 3 collaborations

H Yousuf 2 collaborations

G A Somsen 2 collaborations

Pim van der Harst 2 collaborations

Govert Sweep 2 collaborations

Eric van Gorp 2 collaborations

Erik Scherder 2 collaborations

Michiel L Bots 2 collaborations

T Leiner 2 collaborations

M M Winter 2 collaborations

Maarten Jan Cramer 2 collaborations

Martijn Hofstra 2 collaborations

Folkert W Asselbergs 2 collaborations

Eric Boersma 2 collaborations

Sophie Heleen Bots 2 collaborations

Gerard Pasterkamp 2 collaborations

R Reintjens 1 collaboration

E Slipszenko 1 collaboration

S Blok 1 collaboration

I I Tulevski 1 collaboration

C K M Boerhout 1 collaboration

R G T Feenstra 1 collaboration

P Ong 1 collaboration

M A M Beijk 1 collaboration

T P van de Hoef 1 collaboration

J J Piek 1 collaboration

Sander van der Linden 1 collaboration

Luke Bredius 1 collaboration

G A Ted van Essen 1 collaboration

Zohar Preminger 1 collaboration

Rutger R van de Leur 1 collaboration

David A Leon 1 collaboration

Ernest Diez-Benavente 1 collaboration

Liesbeth Rozendaal 1 collaboration

Ruben Coronel 1 collaboration

Pieter A Doevendans 1 collaboration

Rutger J Hassink 1 collaboration

René van Es 1 collaboration

Ernest Diez Benavente 1 collaboration

Maarten J Cramer 1 collaboration

Nancy Sweitzer 1 collaboration

Mohammed Y Khanji 1 collaboration

Armida Balawon 1 collaboration

Redha Boubertakh 1 collaboration

Myriam Hunink 1 collaboration

Francesca Pugliese 1 collaboration

Steffen E Petersen 1 collaboration

K R Siegersma 1 collaboration

D P Chew 1 collaboration

J W Verjans 1 collaboration

Michiel T H M Henkens 1 collaboration

Sharon Remmelzwaal 1 collaboration

Ping Wang 1 collaboration

Job A J Verdonschot 1 collaboration

Mark R Hazebroek 1 collaboration

Vanessa P M van Empel 1 collaboration

Joline W J Beulens 1 collaboration

Stephane R B Heymans 1 collaboration

P M Croon 1 collaboration

J L Selder 1 collaboration

C P Allaart 1 collaboration

H Bleijendaal 1 collaboration

S A J Chamuleau 1 collaboration

I Išgum 1 collaboration

K A Ziesemer 1 collaboration

G L Habib 1 collaboration

L Bredius 1 collaboration

N R Bindraban 1 collaboration

E J A Scherder 1 collaboration

S van der Linden 1 collaboration

J Narula 1 collaboration

Robin W M Vernooij 1 collaboration

Anne-Mar L N van Ommen 1 collaboration

Leo Hofstra 1 collaboration

Marianne C Verhaar 1 collaboration

Jonathan Corbin 1 collaboration

Peter Paul Zwetsloot 1 collaboration

Jiayu Zhao 1 collaboration

Bert van Rossum 1 collaboration

Ting Jiang 1 collaboration

Jan-Willem Lindemans 1 collaboration

T Vromen 1 collaboration

R W M Brouwers 1 collaboration

H T Jorstad 1 collaboration

R A Kraaijenhagen 1 collaboration

R F Spee 1 collaboration

M E Wittekoek 1 collaboration

M J Cramer 1 collaboration

J M C van Hal 1 collaboration

P M J C Kuijpers 1 collaboration

E C de Melker 1 collaboration

S F Rodrigo 1 collaboration

M Sunamura 1 collaboration

N H M K Uszko-Lencer 1 collaboration

H M Kemps 1 collaboration

Karolina Andrzejczyk 1 collaboration

Sabrina Abou Kamar 1 collaboration

Elisa Dal Canto 1 collaboration

Teun B Petersen 1 collaboration

Gideon Valstar 1 collaboration

K Martijn Akkerhuis 1 collaboration

Victor Umans 1 collaboration

Arco Teske 1 collaboration

Bas M van Dalen 1 collaboration

Marianne Verhaar 1 collaboration

Jasper Brugts 1 collaboration

Folkert Asselbergs 1 collaboration

Hester den Ruijter 1 collaboration

Isabella Kardys 1 collaboration

Aernout G Somsen 1 collaboration

Aisha Gohar 1 collaboration

Maarten Jan Maria Cramer 1 collaboration

Leonardo P Suciadi 1 collaboration

Michael L Bots 1 collaboration

Marlise N Gunning 1 collaboration

Cindy Meun 1 collaboration

Bas B van Rijn 1 collaboration

Nadine M P Daan 1 collaboration

Jeanine E Roeters van Lennep 1 collaboration

Clemens G K M Fauser 1 collaboration

Oscar L Rueda-Ochoa 1 collaboration

Mohammad A Ikram 1 collaboration

Maryam Kavousi 1 collaboration

Cornelis B Lambalk 1 collaboration

Marinus J C Eijkemans 1 collaboration

Joop S E Laven 1 collaboration

Bart C J M Fauser 1 collaboration

None None 1 collaboration

Jan Tijssen 1 collaboration

Brian Leenen 1 collaboration

Jan Willem Lindemans 1 collaboration

Albert van Rossum 1 collaboration

L M Overmars 1 collaboration

Daniek Kapteijn 1 collaboration

Johan H C Reiber 1 collaboration

David Hautemann 1 collaboration

Marianne E Wittekoek 1 collaboration

Saskia Haitjema 1 collaboration

Imo Hoefer 1 collaboration

Roel S Driessen 1 collaboration

Pepijn A van Diemen 1 collaboration

Pieter G Raijmakers 1 collaboration

Juhani Knuuti 1 collaboration

Teemu Maaniitty 1 collaboration

S Richard Underwood 1 collaboration

Eike Nagel 1 collaboration

Lourens F H J Robbers 1 collaboration

Ahmet Demirkiran 1 collaboration

Martin B von Bartheld 1 collaboration

Peter M van de Ven 1 collaboration

Ronald Boellaard 1 collaboration

Albert C van Rossum 1 collaboration

Ibrahim Danad 1 collaboration

Paul Knaapen 1 collaboration

Maxime Evers 1 collaboration

Marco Spruit 1 collaboration

Willemijn J Op den Brouw 1 collaboration

Stephanie B H Gumbs 1 collaboration

Arjen J Stam 1 collaboration

Tania Mudrikova 1 collaboration

Pauline J Schipper 1 collaboration

Andy I M Hoepelman 1 collaboration

Petra M van Ham 1 collaboration

Anne L Borst 1 collaboration

LMarije Hofstra 1 collaboration

Lavina Gharu 1 collaboration

Stephanie van Wyk 1 collaboration

Eduan Wilkinson 1 collaboration

Lot D de Witte 1 collaboration

Annemarie M J Wensing 1 collaboration

Monique Nijhuis 1 collaboration

Niels A Stens 1 collaboration

J W Benjamins 1 collaboration

K van Leeuwen 1 collaboration

M Rienstra 1 collaboration

W Nijhof 1 collaboration

B Verlaat 1 collaboration

I Everts 1 collaboration

H M den Ruijter 1 collaboration

I Isgum 1 collaboration

R Vliegenthart 1 collaboration

F W Asselbergs 1 collaboration

L E Juarez-Orozco 1 collaboration

P van der Harst 1 collaboration