Linus Wahnschaffe

Affiliations

Department I of Internal Medicine, Center for Integrated Oncology, Aachen-Bonn-Cologne-Duesseldorf, Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases, Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

Publications (11)

Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic Leukemia.

Cancer research

Avec: Till Braun , Johanna Stachelscheid , Nadine Bley , Sebastian Oberbeck , Moritz Otte , Tony Andreas Müller , Linus Wahnschaffe , Markus Glaß , Katharina Ommer , Marek Franitza , Birgit Gathof , Janine Altmüller , Michael Hallek , Daniel Auguin , Stefan Hüttelmaier , Alexandra Schrader , Marco Herling

Proteogenomics refines the molecular classification of chronic lymphocytic leukemia.

Nature communications

Avec: Sophie A Herbst , Mattias Vesterlund , Alexander J Helmboldt , Rozbeh Jafari , Ioannis Siavelis , Matthias Stahl , Eva C Schitter , Nora Liebers , Berit J Brinkmann , Felix Czernilofsky , Tobias Roider , Peter-Martin Bruch , Murat Iskar , Adam Kittai , Ying Huang , Junyan Lu , Sarah Richter , Georgios Mermelekas , Husen Muhammad Umer , Mareike Knoll , Carolin Kolb , Angela Lenze , Xiaofang Cao , Cecilia Österholm , Linus Wahnschaffe , Carmen Herling , Sebastian Scheinost , Matthias Ganzinger , Larry Mansouri , Katharina Kriegsmann , Mark Kriegsmann , Simon Anders , Marc Zapatka , Giovanni Del Poeta , Antonella Zucchetto , Riccardo Bomben , Valter Gattei , Peter Dreger , Jennifer Woyach , Marco Herling , Carsten Müller-Tidow , Richard Rosenquist , Stephan Stilgenbauer , Thorsten Zenz , Wolfgang Huber , Eugen Tausch , Janne Lehtiö , Sascha Dietrich

Computational gene expression analysis reveals distinct molecular subgroups of T-cell prolymphocytic leukemia.

PloS one

Avec: Nathan Mikhaylenko , Linus Wahnschaffe , Marco Herling , Ingo Roeder , Michael Seifert

Advances and Perspectives in the Treatment of T-PLL.

Current hematologic malignancy reports

Avec: Till Braun , Jana von Jan , Linus Wahnschaffe , Marco Herling

CCR7 as a novel therapeutic target in t-cell PROLYMPHOCYTIC leukemia.

Biomarker research

Avec: Carlos Cuesta-Mateos , Patricia Fuentes , Alexandra Schrader , Raquel Juárez-Sánchez , Javier Loscertales , Tamara Mateu-Albero , Lorena Vega-Piris , Marina Espartero-Santos , Ana Marcos-Jimenez , Blanca Andrea Sánchez-López , Yaiza Pérez-García , Dennis Jungherz , Sebastian Oberbeck , Linus Wahnschaffe , Anna Kreutzman , Emma I Andersson , Satu Mustjoki , Edgar Faber , Ana Urzainqui , Manuel Fresno , Kostantino Stamatakis , Arantzazu Alfranca , Fernando Terrón , Marco Herling , María Luisa Toribio , Cecilia Muñoz-Calleja

JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL.

Cancers

Avec: Linus Wahnschaffe , Till Braun , Sanna Timonen , Anil K Giri , Alexandra Schrader , Prerana Wagle , Henrikki Almusa , Patricia Johansson , Dorine Bellanger , Cristina López , Claudia Haferlach , Marc-Henri Stern , Jan Dürig , Reiner Siebert , Satu Mustjoki , Tero Aittokallio , Marco Herling

Noncanonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling.

Blood

Avec: S Oberbeck , A Schrader , K Warner , D Jungherz , G Crispatzu , J von Jan , M Chmielewski , A Ianevski , H H Diebner , P Mayer , A Kondo Ados , L Wahnschaffe , T Braun , T A Müller , P Wagle , A Bouska , T Neumann , S Pützer , L Varghese , N Pflug , M Thelen , J Makalowski , N Riet , H J M Göx , G Rappl , J Altmüller , M Kotrová , T Persigehl , G Hopfinger , M L Hansmann , H Schlößer , S Stilgenbauer , J Dürig , D Mougiakakos , M von Bergwelt-Baildon , I Roeder , S Hartmann , M Hallek , R Moriggl , M Brüggemann , T Aittokallio , J Iqbal , S Newrzela , H Abken , M Herling

Case Report: Large Granular Lymphocyte Leukemia (LGLL)-A Case Series of Challenging Presentations.

Frontiers in oncology

Avec: Natali Pflug , Annika Littauer , David Beverungen , Aleksandra Sretenovic , Linus Wahnschaffe , Till Braun , Annika Dechow , Dennis Jungherz , Moritz Otte , Astrid Monecke , Enrica Bach , Georg-Nikolaus Franke , Sebastian Schwind , Madlen Jentzsch , Uwe Platzbecker , Marco Herling , Vladan Vucinic

Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways.

Haematologica

Avec: Till Braun , Markus Glass , Linus Wahnschaffe , Moritz Otte , Petra Mayer , Marek Franitza , Janine Altmüller , Michael Hallek , Stefan Hüttelmaier , Alexandra Schrader , Marco Herling

The miR-141/200c-STAT4 Axis Contributes to Leukemogenesis by Enhancing Cell Proliferation in T-PLL.

Cancers

Avec: Moritz Otte , Johanna Stachelscheid , Markus Glaß , Linus Wahnschaffe , Qu Jiang , Waseem Lone , Aleksandr Ianevski , Tero Aittokallio , Javeed Iqbal , Michael Hallek , Stefan Hüttelmaier , Alexandra Schrader , Till Braun , Marco Herling

Optimizing Drug Combinations for T-PLL: Restoring DNA Damage and P53-Mediated Apoptotic Responses.

Blood

Avec: Jana von Jan , Sanna Timonen , Till Braun , Qu Jiang , Aleksandr Ianevski , Yayi Peng , Kathleen McConnell , Paola Sindaco , Tony Andreas Müller , Sabine Pützer , Hanna Klepzig , Dennis Jungherz , Annika Dechow , Linus Wahnschaffe , Anil K Giri , Matti Kankainen , Heikki Kuusanmäki , Heidi A Neubauer , Richard H Moriggl , Paolo Mazzeo , Nicole Schmidt , Raphael Koch , Michael J Hallek , Amel Chebel , David Armisen , Laurent Genestier , Emmanuel Bachy , Anjali Mishra , Alexandra Schrader , Tero Aittokallio , Satu Mustjoki , Marco Herling

Réseau de co-auteurs

Marco Herling 10 collaborations

Till Braun 7 collaborations

Alexandra Schrader 6 collaborations

Moritz Otte 4 collaborations

Michael Hallek 3 collaborations

Stefan Hüttelmaier 3 collaborations

Dennis Jungherz 3 collaborations

Satu Mustjoki 3 collaborations

Tero Aittokallio 3 collaborations

Johanna Stachelscheid 2 collaborations

Sebastian Oberbeck 2 collaborations

Tony Andreas Müller 2 collaborations

Markus Glaß 2 collaborations

Marek Franitza 2 collaborations

Janine Altmüller 2 collaborations

Jana von Jan 2 collaborations

Sanna Timonen 2 collaborations

Anil K Giri 2 collaborations

Annika Dechow 2 collaborations

Qu Jiang 2 collaborations

Aleksandr Ianevski 2 collaborations

Nadine Bley 1 collaboration

Katharina Ommer 1 collaboration

Birgit Gathof 1 collaboration

Daniel Auguin 1 collaboration

Sophie A Herbst 1 collaboration

Mattias Vesterlund 1 collaboration

Alexander J Helmboldt 1 collaboration

Rozbeh Jafari 1 collaboration

Ioannis Siavelis 1 collaboration

Matthias Stahl 1 collaboration

Eva C Schitter 1 collaboration

Nora Liebers 1 collaboration

Berit J Brinkmann 1 collaboration

Felix Czernilofsky 1 collaboration

Tobias Roider 1 collaboration

Peter-Martin Bruch 1 collaboration

Murat Iskar 1 collaboration

Adam Kittai 1 collaboration

Ying Huang 1 collaboration

Junyan Lu 1 collaboration

Sarah Richter 1 collaboration

Georgios Mermelekas 1 collaboration

Husen Muhammad Umer 1 collaboration

Mareike Knoll 1 collaboration

Carolin Kolb 1 collaboration

Angela Lenze 1 collaboration

Xiaofang Cao 1 collaboration

Cecilia Österholm 1 collaboration

Carmen Herling 1 collaboration

Sebastian Scheinost 1 collaboration

Matthias Ganzinger 1 collaboration

Larry Mansouri 1 collaboration

Katharina Kriegsmann 1 collaboration

Mark Kriegsmann 1 collaboration

Simon Anders 1 collaboration

Marc Zapatka 1 collaboration

Giovanni Del Poeta 1 collaboration

Antonella Zucchetto 1 collaboration

Riccardo Bomben 1 collaboration

Valter Gattei 1 collaboration

Peter Dreger 1 collaboration

Jennifer Woyach 1 collaboration

Carsten Müller-Tidow 1 collaboration

Richard Rosenquist 1 collaboration

Stephan Stilgenbauer 1 collaboration

Thorsten Zenz 1 collaboration

Wolfgang Huber 1 collaboration

Eugen Tausch 1 collaboration

Janne Lehtiö 1 collaboration

Sascha Dietrich 1 collaboration

Nathan Mikhaylenko 1 collaboration

Ingo Roeder 1 collaboration

Michael Seifert 1 collaboration

Carlos Cuesta-Mateos 1 collaboration

Patricia Fuentes 1 collaboration

Raquel Juárez-Sánchez 1 collaboration

Javier Loscertales 1 collaboration

Tamara Mateu-Albero 1 collaboration

Lorena Vega-Piris 1 collaboration

Marina Espartero-Santos 1 collaboration

Ana Marcos-Jimenez 1 collaboration

Blanca Andrea Sánchez-López 1 collaboration

Yaiza Pérez-García 1 collaboration

Anna Kreutzman 1 collaboration

Emma I Andersson 1 collaboration

Edgar Faber 1 collaboration

Ana Urzainqui 1 collaboration

Manuel Fresno 1 collaboration

Kostantino Stamatakis 1 collaboration

Arantzazu Alfranca 1 collaboration

Fernando Terrón 1 collaboration

María Luisa Toribio 1 collaboration

Cecilia Muñoz-Calleja 1 collaboration

Prerana Wagle 1 collaboration

Henrikki Almusa 1 collaboration

Patricia Johansson 1 collaboration

Dorine Bellanger 1 collaboration

Cristina López 1 collaboration

Claudia Haferlach 1 collaboration

Marc-Henri Stern 1 collaboration

Jan Dürig 1 collaboration

Reiner Siebert 1 collaboration

S Oberbeck 1 collaboration

A Schrader 1 collaboration

K Warner 1 collaboration

D Jungherz 1 collaboration

G Crispatzu 1 collaboration

J von Jan 1 collaboration

M Chmielewski 1 collaboration

A Ianevski 1 collaboration

H H Diebner 1 collaboration

P Mayer 1 collaboration

A Kondo Ados 1 collaboration

L Wahnschaffe 1 collaboration

T Braun 1 collaboration

T A Müller 1 collaboration

P Wagle 1 collaboration

A Bouska 1 collaboration

T Neumann 1 collaboration

S Pützer 1 collaboration

L Varghese 1 collaboration

N Pflug 1 collaboration

M Thelen 1 collaboration

J Makalowski 1 collaboration

N Riet 1 collaboration

H J M Göx 1 collaboration

G Rappl 1 collaboration

J Altmüller 1 collaboration

M Kotrová 1 collaboration

T Persigehl 1 collaboration

G Hopfinger 1 collaboration

M L Hansmann 1 collaboration

H Schlößer 1 collaboration

S Stilgenbauer 1 collaboration

J Dürig 1 collaboration

D Mougiakakos 1 collaboration

M von Bergwelt-Baildon 1 collaboration

I Roeder 1 collaboration

S Hartmann 1 collaboration

M Hallek 1 collaboration

R Moriggl 1 collaboration

M Brüggemann 1 collaboration

T Aittokallio 1 collaboration

J Iqbal 1 collaboration

S Newrzela 1 collaboration

H Abken 1 collaboration

M Herling 1 collaboration

Natali Pflug 1 collaboration

Annika Littauer 1 collaboration

David Beverungen 1 collaboration

Aleksandra Sretenovic 1 collaboration

Astrid Monecke 1 collaboration

Enrica Bach 1 collaboration

Georg-Nikolaus Franke 1 collaboration

Sebastian Schwind 1 collaboration

Madlen Jentzsch 1 collaboration

Uwe Platzbecker 1 collaboration

Vladan Vucinic 1 collaboration

Markus Glass 1 collaboration

Petra Mayer 1 collaboration

Waseem Lone 1 collaboration

Javeed Iqbal 1 collaboration

Yayi Peng 1 collaboration

Kathleen McConnell 1 collaboration

Paola Sindaco 1 collaboration

Sabine Pützer 1 collaboration

Hanna Klepzig 1 collaboration

Matti Kankainen 1 collaboration

Heikki Kuusanmäki 1 collaboration

Heidi A Neubauer 1 collaboration

Richard H Moriggl 1 collaboration

Paolo Mazzeo 1 collaboration

Nicole Schmidt 1 collaboration

Raphael Koch 1 collaboration

Michael J Hallek 1 collaboration

Amel Chebel 1 collaboration

David Armisen 1 collaboration

Laurent Genestier 1 collaboration

Emmanuel Bachy 1 collaboration

Anjali Mishra 1 collaboration