R Moriggl

Affiliations
  • Institute of Animal Breeding and Genetics, Unit of Functional Cancer Genomics, University of Veterinary Medicine Vienna, 1210, Vienna, Austria.

Publications (63)

Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function.

Immunity
Avec: Alexander Lercher , Anannya Bhattacharya , Alexandra M Popa , Michael Caldera , Moritz F Schlapansky , Hatoon Baazim , Benedikt Agerer , Bettina Gürtl , Lindsay Kosack , Peter Májek , Julia S Brunner , Dijana Vitko , Theresa Pinter , Jakob-Wendelin Genger , Anna Orlova , Natalia Pikor , Daniela Reil , Maria Ozsvár-Kozma , Ulrich Kalinke , Burkhard Ludewig , Richard Moriggl , Keiryn L Bennett , Jörg Menche , Paul N Cheng , Gernot Schabbauer , Michael Trauner , Kristaps Klavins , Andreas Bergthaler

Advances in covalent kinase inhibitors.

Chemical Society reviews
Avec: Ayah Abdeldayem , Yasir S Raouf , Stefan N Constantinescu , Richard Moriggl , Patrick T Gunning

Retraction Note: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.

Cell death & disease
Avec: Tahereh Javaheri , Zahra Kazemi , Jan Pencik , Ha T T Pham , Maximilian Kauer , Rahil Noorizadeh , Barbara Sax , Harini Nivarthi , Michaela Schlederer , Barbara Maurer , Maximillian Hofbauer , Dave N T Aryee , Marc Wiedner , Eleni M Tomazou , Malcolm Logan , Christine Hartmann , Jan P Tuckermann , Lukas Kenner , Mario Mikula , Helmut Dolznig , Aykut Üren , Günther H Richter , Florian Grebien , Heinrich Kovar , Richard Moriggl

Cell Metabolism Control Through O-GlcNAcylation of STAT5: A Full or Empty Fuel Tank Makes a Big Difference for Cancer Cell Growth and Survival.

International journal of molecular sciences
Avec: Manuel Rauth , Patricia Freund , Anna Orlova , Stefan Grünert , Nikola Tasic , Xiaonan Han , Hai-Bin Ruan , Heidi A Neubauer , Richard Moriggl

Structural and functional consequences of the STAT5B

Nature communications
Avec: Elvin D de Araujo , Fettah Erdogan , Heidi A Neubauer , Deniz Meneksedag-Erol , Pimyupa Manaswiyoungkul , Mohammad S Eram , Hyuk-Soo Seo , Abdul K Qadree , Johan Israelian , Anna Orlova , Tobias Suske , Ha T T Pham , Auke Boersma , Simone Tangermann , Lukas Kenner , Thomas Rülicke , Aiping Dong , Manimekalai Ravichandran , Peter J Brown , Gerald F Audette , Sarah Rauscher , Sirano Dhe-Paganon , Richard Moriggl , Patrick T Gunning

Efficacy and Synergy of Small Molecule Inhibitors Targeting

Cancers
Avec: Javier Bregante , Anna Schönbichler , Daniel Pölöske , Lina Degenfeld-Schonburg , Garazi Monzó Contreras , Emir Hadzijusufovic , Elvin D de Araujo , Peter Valent , Richard Moriggl , Anna Orlova

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.

Oncogene
Avec: Alexander Swoboda , Robert Soukup , Oliver Eckel , Katharina Kinslechner , Bettina Wingelhofer , David Schörghofer , Christina Sternberg , Ha T T Pham , Maria Vallianou , Jaqueline Horvath , Dagmar Stoiber , Lukas Kenner , Lionel Larue , Valeria Poli , Friedrich Beermann , Takashi Yokota , Stefan Kubicek , Thomas Krausgruber , André F Rendeiro , Christoph Bock , Rainer Zenz , Boris Kovacic , Fritz Aberger , Markus Hengstschläger , Peter Petzelbauer , Mario Mikula , Richard Moriggl

A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells.

Blood
Avec: Sebastian Kollmann , Reinhard Grausenburger , Thorsten Klampfl , Michaela Prchal-Murphy , Klavdija Bastl , Hanja Pisa , Vanessa M Knab , Tania Brandstoetter , Eszter Doma , Wolfgang R Sperr , Sabine Lagger , Matthias Farlik , Richard Moriggl , Peter Valent , Florian Halbritter , Karoline Kollmann , Gerwin Heller , Barbara Maurer , Veronika Sexl

PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.

Molecular cancer
Avec: I Garces de Los Fayos Alonso , L Zujo , I Wiest , P Kodajova , G Timelthaler , S Edtmayer , M Zrimšek , S Kollmann , C Giordano , M Kothmayer , H A Neubauer , S Dey , M Schlederer , B S Schmalzbauer , T Limberger , C Probst , O Pusch , S Högler , S Tangermann , O Merkel , A I Schiefer , C Kornauth , N Prutsch , M Zimmerman , B Abraham , J Anagnostopoulos , L Quintanilla-Martinez , S Mathas , P Wolf , D Stoiber , P B Staber , G Egger , W Klapper , W Woessmann , T A Look , P Gunning , S D Turner , R Moriggl , S Lagger , L Kenner

Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia.

Genes & diseases
Avec: Dongsheng Zhang , Wenjuan Tang , Haitao Niu , William Tse , Hai-Bin Ruan , Helmut Dolznig , Thomas Knösel , Friedrich Karl-Heinz , Madeleine Themanns , Jiang Wang , Mingquan Song , Lee Denson , Lukas Kenner , Richard Moriggl , Yi Zheng , Xiaonan Han

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.

Blood
Avec: Johannes Schmoellerl , Inês Amorim Monteiro Barbosa , Thomas Eder , Tania Brandstoetter , Luisa Schmidt , Barbara Maurer , Selina Troester , Ha Thi Thanh Pham , Mohanty Sagarajit , Jessica Ebner , Gabriele Manhart , Ezgi Aslan , Stefan Terlecki-Zaniewicz , Christa Van der Veen , Gregor Hoermann , Nicolas Duployez , Arnaud Petit , Helene Lapillonne , Alexandre Puissant , Raphael Itzykson , Richard Moriggl , Michael Heuser , Roland Meisel , Peter Valent , Veronika Sexl , Johannes Zuber , Florian Grebien

Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.

Leukemia
Avec: Nicole Prutsch , Elisabeth Gurnhofer , Tobias Suske , Huan Chang Liang , Michaela Schlederer , Simone Roos , Lawren C Wu , Ingrid Simonitsch-Klupp , Andrea Alvarez-Hernandez , Christoph Kornauth , Dario A Leone , Jasmin Svinka , Robert Eferl , Tanja Limberger , Astrid Aufinger , Nitesh Shirsath , Peter Wolf , Thomas Hielscher , Christina Sternberg , Fritz Aberger , Johannes Schmoellerl , Dagmar Stoiber , Birgit Strobl , Ulrich Jäger , Philipp B Staber , Florian Grebien , Richard Moriggl , Mathias Müller , Giorgio G Inghirami , Takaomi Sanda , A Thomas Look , Suzanne D Turner , Lukas Kenner , Olaf Merkel

STAT5a/b Deficiency Delays, but does not Prevent, Prolactin-Driven Prostate Tumorigenesis in Mice.

Cancers
Avec: Florence Boutillon , Natascha Pigat , Lucila Sackmann Sala , Edouard Reyes-Gomez , Richard Moriggl , Jacques-Emmanuel Guidotti , Vincent Goffin

Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases.

Cytokine
Avec: J Catharina Duvigneau , Andreia Luís , Adrienne M Gorman , Afshin Samali , Doris Kaltenecker , Richard Moriggl , Andrey V Kozlov

Interplay of transcription factors STAT3, STAT1 and AP-1 mediates activity of the matrix metallo-proteinase-1 promoter in colorectal carcinoma cells.

Neoplasma
Avec: A Muller , J Gasch , K F Albring , F Aberger , H Nivarthi , M Khemeri , R Moriggl , K H Friedrich

Direct Targeting Options for STAT3 and STAT5 in Cancer.

Cancers
Avec: Anna Orlova , Christina Wagner , Elvin D de Araujo , Dávid Bajusz , Heidi A Neubauer , Marco Herling , Patrick T Gunning , György M Keserű , Richard Moriggl

Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3.

Neoplasia (New York, N.Y.)
Avec: Sabrina Tripolt , Heidi A Neubauer , Vanessa M Knab , Dominik P Elmer , Fritz Aberger , Richard Moriggl , Daniela A Fux

Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia.

Journal of medicinal chemistry
Avec: Krimo Toutah , Nabanita Nawar , Sanna Timonen , Helena Sorger , Yasir S Raouf , Shazreh Bukhari , Jana von Jan , Aleksandr Ianevski , Justyna M Gawel , Olasunkanmi O Olaoye , Mulu Geletu , Ayah Abdeldayem , Johan Israelian , Tudor B Radu , Abootaleb Sedighi , Muzaffar N Bhatti , Muhammad Murtaza Hassan , Pimyupa Manaswiyoungkul , Andrew E Shouksmith , Heidi A Neubauer , Elvin D de Araujo , Tero Aittokallio , Oliver H Krämer , Richard Moriggl , Satu Mustjoki , Marco Herling , Patrick T Gunning

Proposed refined diagnostic criteria and classification of eosinophil disorders and related syndromes.

Allergy
Avec: Peter Valent , Amy D Klion , Florence Roufosse , Dagmar Simon , Georgia Metzgeroth , Kristin M Leiferman , Juliana Schwaab , Joseph H Butterfield , Wolfgang R Sperr , Karl Sotlar , Peter Vandenberghe , Gregor Hoermann , Torsten Haferlach , Richard Moriggl , Tracy I George , Cem Akin , Bruce S Bochner , Jason Gotlib , Andreas Reiter , Hans-Peter Horny , Michel Arock , Hans-Uwe Simon , Gerald J Gleich

Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors.

Journal of medicinal chemistry
Avec: Aaron B Keeley , Aleksandra Kopranovic , Vincenzo Di Lorenzo , Péter Ábrányi-Balogh , Niklas Jänsch , Linh N Lai , László Petri , Zoltán Orgován , Daniel Pölöske , Anna Orlova , András György Németh , Charlotte Desczyk , Tímea Imre , Dávid Bajusz , Richard Moriggl , Franz-Josef Meyer-Almes , György M Keserü

JAK-STAT signaling maintains homeostasis in T cells and macrophages.

Nature immunology
Avec: Nikolaus Fortelny , Matthias Farlik , Victoria Fife , Anna-Dorothea Gorki , Caroline Lassnig , Barbara Maurer , Katrin Meissl , Marlies Dolezal , Laura Boccuni , Aarathy Ravi Sundar Jose Geetha , Mojoyinola Joanna Akagha , Anzhelika Karjalainen , Stephen Shoebridge , Asma Farhat , Ulrike Mann , Rohit Jain , Shweta Tikoo , Nina Zila , Wolfgang Esser-Skala , Thomas Krausgruber , Katarzyna Sitnik , Thomas Penz , Anastasiya Hladik , Tobias Suske , Sophie Zahalka , Martin Senekowitsch , Daniele Barreca , Florian Halbritter , Sabine Macho-Maschler , Wolfgang Weninger , Heidi A Neubauer , Richard Moriggl , Sylvia Knapp , Veronika Sexl , Birgit Strobl , Thomas Decker , Mathias Müller , Christoph Bock

JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.

Molecular cancer
Avec: Torben Redmer , Martin Raigel , Christina Sternberg , Roman Ziegler , Clara Probst , Desiree Lindner , Astrid Aufinger , Tanja Limberger , Karolina Trachtova , Petra Kodajova , Sandra Högler , Michaela Schlederer , Stefan Stoiber , Monika Oberhuber , Marco Bolis , Heidi A Neubauer , Sara Miranda , Martina Tomberger , Nora S Harbusch , Ines Garces de Los Fayos Alonso , Felix Sternberg , Richard Moriggl , Jean-Philippe Theurillat , Boris Tichy , Vojtech Bystry , Jenny L Persson , Stephan Mathas , Fritz Aberger , Birgit Strobl , Sarka Pospisilova , Olaf Merkel , Gerda Egger , Sabine Lagger , Lukas Kenner

High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.

Haematologica
Avec: Barbara Maurer , Harini Nivarthi , Bettina Wingelhofer , Ha Thi Thanh Pham , Michaela Schlederer , Tobias Suske , Reinhard Grausenburger , Ana-Iris Schiefer , Michaela Prchal-Murphy , Doris Chen , Susanne Winkler , Olaf Merkel , Christoph Kornauth , Maximilian Hofbauer , Birgit Hochgatterer , Gregor Hoermann , Andrea Hoelbl-Kovacic , Jana Prochazkova , Cosimo Lobello , Abbarna A Cumaraswamy , Johanna Latzka , Melitta Kitzwögerer , Andreas Chott , Andrea Janikova , Šárka Pospíšilova , Joanna I Loizou , Stefan Kubicek , Peter Valent , Thomas Kolbe , Florian Grebien , Lukas Kenner , Patrick T Gunning , Robert Kralovics , Marco Herling , Mathias Müller , Thomas Rülicke , Veronika Sexl , Richard Moriggl

Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer.

Angiogenesis
Avec: Daniela Unterleuthner , Patrick Neuhold , Katharina Schwarz , Lukas Janker , Benjamin Neuditschko , Harini Nivarthi , Ilija Crncec , Nina Kramer , Christine Unger , Markus Hengstschläger , Robert Eferl , Richard Moriggl , Wolfgang Sommergruber , Christopher Gerner , Helmut Dolznig

Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice.

PloS one
Avec: Marianna Beghini , Theresia Wagner , Andreea Corina Luca , Matthäus Metz , Doris Kaltenecker , Katrin Spirk , Martina Theresa Hackl , Johannes Haybaeck , Richard Moriggl , Alexandra Kautzky-Willer , Thomas Scherer , Clemens Fürnsinn

Proteomic Analysis Identifies NDUFS1 and ATP5O as Novel Markers for Survival Outcome in Prostate Cancer.

Cancers
Avec: Robert Wiebringhaus , Matteo Pecoraro , Heidi A Neubauer , Karolína Trachtová , Bettina Trimmel , Maritta Wieselberg , Jan Pencik , Gerda Egger , Christoph Krall , Richard Moriggl , Matthias Mann , Brigitte Hantusch , Lukas Kenner

A hydride transfer complex reprograms NAD metabolism and bypasses senescence.

Molecular cell
Avec: Sebastian Igelmann , Frédéric Lessard , Oro Uchenunu , Jacob Bouchard , Ana Fernandez-Ruiz , Marie-Camille Rowell , Stéphane Lopes-Paciencia , David Papadopoli , Aurélien Fouillen , Katia Julissa Ponce , Geneviève Huot , Lian Mignacca , Mehdi Benfdil , Paloma Kalegari , Haytham M Wahba , Jan Pencik , Nhung Vuong , Jordan Quenneville , Jordan Guillon , Véronique Bourdeau , Laura Hulea , Etienne Gagnon , Lukas Kenner , Richard Moriggl , Antonio Nanci , Michael N Pollak , James G Omichinski , Ivan Topisirovic , Gerardo Ferbeyre

A centric view of JAK/STAT5 in intestinal homeostasis, infection, and inflammation.

Cytokine
Avec: Marta Surbek , William Tse , Richard Moriggl , Xiaonan Han

STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation.

Leukemia
Avec: Daehong Kim , Giljun Park , Jani Huuhtanen , Bishwa Ghimire , Hanna Rajala , Richard Moriggl , Wing C Chan , Matti Kankainen , Mikko Myllymäki , Satu Mustjoki

Oncogenic Kinase Cascades Induce Molecular Mechanisms That Protect Leukemic Cell Models from Lethal Effects of De Novo dNTP Synthesis Inhibition.

Cancers
Avec: Miriam Pons , Yanira Zeyn , Stella Zahn , Nisintha Mahendrarajah , Brent D G Page , Patrick T Gunning , Richard Moriggl , Walburgis Brenner , Falk Butter , Oliver H Krämer

Proposed Diagnostic Criteria and Classification of Canine Mast Cell Neoplasms: A Consensus Proposal.

Frontiers in veterinary science
Avec: Michael Willmann , Vilma Yuzbasiyan-Gurkan , Laura Marconato , Mauro Dacasto , Emir Hadzijusufovic , Olivier Hermine , Irina Sadovnik , Susanne Gamperl , Mathias Schneeweiss-Gleixner , Karoline V Gleixner , Thomas Böhm , Barbara Peter , Gregor Eisenwort , Richard Moriggl , Zhixiong Li , Mohamad Jawhar , Karl Sotlar , Erika Jensen-Jarolim , Veronika Sexl , Hans-Peter Horny , Stephen J Galli , Michel Arock , David M Vail , Matti Kiupel , Peter Valent

Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma.

EMBO molecular medicine
Avec: Helena Sorger , Saptaswa Dey , Pablo Augusto Vieyra-Garcia , Daniel Pölöske , Andrea R Teufelberger , Elvin D de Araujo , Abootaleb Sedighi , Ricarda Graf , Benjamin Spiegl , Isaac Lazzeri , Till Braun , Ines Garces de Los Fayos Alonso , Michaela Schlederer , Gerald Timelthaler , Petra Kodajova , Christine Pirker , Marta Surbek , Michael Machtinger , Thomas Graier , Isabella Perchthaler , Yi Pan , Regina Fink-Puches , Lorenzo Cerroni , Jennifer Ober , Moritz Otte , Jana D Albrecht , Gary Tin , Ayah Abdeldayem , Pimyupa Manaswiyoungkul , Olasunkanmi O Olaoye , Martin L Metzelder , Anna Orlova , Walter Berger , Marion Wobser , Jan P Nicolay , Fiona André , Van Anh Nguyen , Heidi A Neubauer , Roman Fleck , Olaf Merkel , Marco Herling , Ellen Heitzer , Patrick T Gunning , Lukas Kenner , Richard Moriggl , Peter Wolf

STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.

Molecular cancer
Avec: Jan Pencik , Cecile Philippe , Michaela Schlederer , Emine Atas , Matteo Pecoraro , Sandra Grund-Gröschke , Wen Jess Li , Amanda Tracz , Isabel Heidegger , Sabine Lagger , Karolína Trachtová , Monika Oberhuber , Ellen Heitzer , Osman Aksoy , Heidi A Neubauer , Bettina Wingelhofer , Anna Orlova , Nadine Witzeneder , Thomas Dillinger , Elisa Redl , Georg Greiner , David D'Andrea , Johnny R Östman , Simone Tangermann , Ivana Hermanova , Georg Schäfer , Felix Sternberg , Elena E Pohl , Christina Sternberg , Adam Varady , Jaqueline Horvath , Dagmar Stoiber , Tim I Malcolm , Suzanne D Turner , Eileen E Parkes , Brigitte Hantusch , Gerda Egger , Stefan Rose-John , Valeria Poli , Suneil Jain , Chris W D Armstrong , Gregor Hoermann , Vincent Goffin , Fritz Aberger , Richard Moriggl , Arkaitz Carracedo , Cathal McKinney , Richard D Kennedy , Helmut Klocker , Michael R Speicher , Dean G Tang , Ali A Moazzami , David M Heery , Marcus Hacker , Lukas Kenner

Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms.

Nature immunology
Avec: Nital Sumaria , Gina J Fiala , Daniel Inácio , Marta Curado-Avelar , Ana Cachucho , Rúben Pinheiro , Robert Wiesheu , Shunsuke Kimura , Lucien Courtois , Birte Blankenhaus , Julie Darrigues , Tobias Suske , Afonso R M Almeida , Susana Minguet , Vahid Asnafi , Ludovic Lhermitte , Charles G Mullighan , Seth B Coffelt , Richard Moriggl , João T Barata , Daniel J Pennington , Bruno Silva-Santos

STAT5 is Expressed in CD34

Cancers
Avec: Emir Hadzijusufovic , Alexandra Keller , Daniela Berger , Georg Greiner , Bettina Wingelhofer , Nadine Witzeneder , Daniel Ivanov , Emmanuel Pecnard , Harini Nivarthi , Florian K M Schur , Yüksel Filik , Christoph Kornauth , Heidi A Neubauer , Leonhard Müllauer , Gary Tin , Jisung Park , Elvin D de Araujo , Patrick T Gunning , Gregor Hoermann , Fabrice Gouilleux , Robert Kralovics , Richard Moriggl , Peter Valent

The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5.

The Journal of clinical investigation
Avec: Darshana Kadekar , Rasmus Agerholm , John Rizk , Heidi A Neubauer , Tobias Suske , Barbara Maurer , Monica Torrellas Viñals , Elena M Comelli , Amel Taibi , Richard Moriggl , Vasileios Bekiaris

Structural Implications of STAT3 and STAT5 SH2 Domain Mutations.

Cancers
Avec: Elvin D de Araujo , Anna Orlova , Heidi A Neubauer , Dávid Bajusz , Hyuk-Soo Seo , Sirano Dhe-Paganon , György M Keserű , Richard Moriggl , Patrick T Gunning

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease.

Cancer cell
Avec: Lindsay Kosack , Bettina Wingelhofer , Alexandra Popa , Anna Orlova , Benedikt Agerer , Bojan Vilagos , Peter Majek , Katja Parapatics , Alexander Lercher , Anna Ringler , Johanna Klughammer , Mark Smyth , Kseniya Khamina , Hatoon Baazim , Elvin D de Araujo , David A Rosa , Jisung Park , Gary Tin , Siawash Ahmar , Patrick T Gunning , Christoph Bock , Hannah V Siddle , Gregory M Woods , Stefan Kubicek , Elizabeth P Murchison , Keiryn L Bennett , Richard Moriggl , Andreas Bergthaler

High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype.

Translational oncology
Avec: Nicole Golob-Schwarzl , Kira Bettermann , Anita Kuldeep Mehta , Sonja M Kessler , Julia Unterluggauer , Stefanie Krassnig , Kensuke Kojima , Xintong Chen , Yujin Hoshida , Nabeel M Bardeesy , Heimo Müller , Vendula Svendova , Michael G Schimek , Clemens Diwoky , Alexandra Lipfert , Vineet Mahajan , Cornelia Stumptner , Andrea Thüringer , Leopold F Fröhlich , Tatjana Stojakovic , K P R Nilsson , Thomas Kolbe , Thomas Rülicke , Thomas M Magin , Pavel Strnad , Alexandra K Kiemer , Richard Moriggl , Johannes Haybaeck

Editorial: Cytokines in liver diseases.

Cytokine
Avec: Subburaj Ilangumaran , Richard Moriggl , Dhan V Kalvakolanu

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.

Leukemia
Avec: Nicole Prutsch , Elisabeth Gurnhofer , Tobias Suske , Huan Chang Liang , Michaela Schlederer , Simone Roos , Lawren C Wu , Ingrid Simonitsch-Klupp , Andrea Alvarez-Hernandez , Christoph Kornauth , Dario A Leone , Jasmin Svinka , Robert Eferl , Tanja Limberger , Astrid Aufinger , Nitesh Shirsath , Peter Wolf , Thomas Hielscher , Christina Sternberg , Fritz Aberger , Johannes Schmoellerl , Dagmar Stoiber , Birgit Strobl , Ulrich Jäger , Philipp B Staber , Florian Grebien , Richard Moriggl , Mathias Müller , Giorgio G Inghirami , Takaomi Sanda , A Thomas Look , Suzanne D Turner , Lukas Kenner , Olaf Merkel

Noncanonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling.

Blood
Avec: S Oberbeck , A Schrader , K Warner , D Jungherz , G Crispatzu , J von Jan , M Chmielewski , A Ianevski , H H Diebner , P Mayer , A Kondo Ados , L Wahnschaffe , T Braun , T A Müller , P Wagle , A Bouska , T Neumann , S Pützer , L Varghese , N Pflug , M Thelen , J Makalowski , N Riet , H J M Göx , G Rappl , J Altmüller , M Kotrová , T Persigehl , G Hopfinger , M L Hansmann , H Schlößer , S Stilgenbauer , J Dürig , D Mougiakakos , M von Bergwelt-Baildon , I Roeder , S Hartmann , M Hallek , R Moriggl , M Brüggemann , T Aittokallio , J Iqbal , S Newrzela , H Abken , M Herling

TYK2 licenses non-canonical inflammasome activation during endotoxemia.

Cell death and differentiation
Avec: Andrea Poelzl , Caroline Lassnig , Simone Tangermann , Dominika Hromadová , Ursula Reichart , Riem Gawish , Kristina Mueller , Richard Moriggl , Andreas Linkermann , Martin Glösmann , Lukas Kenner , Mathias Mueller , Birgit Strobl

JAK-STAT core cancer pathway: An integrative cancer interactome analysis.

Journal of cellular and molecular medicine
Avec: Fettah Erdogan , Tudor Bogdan Radu , Anna Orlova , Abdul Khawazak Qadree , Elvin Dominic de Araujo , Johan Israelian , Peter Valent , Satu M Mustjoki , Marco Herling , Richard Moriggl , Patrick Thomas Gunning

Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade.

Haematologica
Avec: Katharina Woess , Sabine Macho-Maschler , Dorette S Van Ingen Schenau , Miriam Butler , Caroline Lassnig , Daniel Valcanover , Andrea Poelzl , Katrin Meissl , Barbara Maurer , Tania Brandstoetter , Claus Vogl , Anna Koren , Stefan Kubicek , Anna Orlova , Richard Moriggl , Birgit Strobl , Veronika Sexl , Frank N Van Leeuwen , Roland P Kuiper , Mathias Mueller

High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma.

Pharmaceuticals (Basel, Switzerland)
Avec: Harsimran Kaur Garcha , Nabanita Nawar , Helena Sorger , Fettah Erdogan , Myint Myat Khine Aung , Abootaleb Sedighi , Pimyupa Manaswiyoungkul , Hyuk-Soo Seo , Susann Schönefeldt , Daniel Pölöske , Sirano Dhe-Paganon , Heidi A Neubauer , Satu M Mustjoki , Marco Herling , Elvin D de Araujo , Richard Moriggl , Patrick T Gunning

Inhibitor Library Screening of SH2 Domains Through Denaturation-Based Assays.

Methods in molecular biology (Clifton, N.J.)
Avec: Elvin D de Araujo , Anna Orlova , Qirat F Ashraf , Richard Moriggl , Patrick T Gunning

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia.

Nature communications
Avec: Jessica Ebner , Johannes Schmoellerl , Martin Piontek , Gabriele Manhart , Selina Troester , Bing Z Carter , Heidi Neubauer , Richard Moriggl , Gergely Szakács , Johannes Zuber , Thomas Köcher , Michael Andreeff , Wolfgang R Sperr , Peter Valent , Florian Grebien

Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.

The Journal of clinical investigation
Avec: Tobias Suske , Helena Sorger , Gabriele Manhart , Frank Ruge , Nicole Prutsch , Mark W Zimmerman , Thomas Eder , Diaaeldin I Abdallah , Barbara Maurer , Christina Wagner , Susann Schönefeldt , Katrin Spirk , Alexander Pichler , Tea Pemovska , Carmen Schweicker , Daniel Pölöske , Emina Hubanic , Dennis Jungherz , Tony Andreas Müller , Myint Myat Khine Aung , Anna Orlova , Ha Thi Thanh Pham , Kerstin Zimmel , Thomas Krausgruber , Christoph Bock , Mathias Müller , Maik Dahlhoff , Auke Boersma , Thomas Rülicke , Roman Fleck , Elvin Dominic de Araujo , Patrick Thomas Gunning , Tero Aittokallio , Satu Mustjoki , Takaomi Sanda , Sylvia Hartmann , Florian Grebien , Gregor Hoermann , Torsten Haferlach , Philipp Bernhard Staber , Heidi Anne Neubauer , Alfred Thomas Look , Marco Herling , Richard Moriggl

Thyroid and androgen receptor signaling are antagonized by μ-Crystallin in prostate cancer.

International journal of cancer
Avec: Osman Aksoy , Jan Pencik , Markus Hartenbach , Ali A Moazzami , Michaela Schlederer , Theresa Balber , Adam Varady , Cecile Philippe , Pascal A Baltzer , Bismoy Mazumder , Jonathan B Whitchurch , Christopher J Roberts , Andrea Haitel , Merima Herac , Martin Susani , Markus Mitterhauser , Rodrig Marculescu , Judith Stangl-Kremser , Melanie R Hassler , Gero Kramer , Shahrokh F Shariat , Suzanne D Turner , Boris Tichy , Jan Oppelt , Sarka Pospisilova , Sabrina Hartenbach , Simone Tangermann , Gerda Egger , Heidi A Neubauer , Richard Moriggl , Zoran Culig , Georg Greiner , Gregor Hoermann , Marcus Hacker , David M Heery , Olaf Merkel , Lukas Kenner

Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions.

HemaSphere
Avec: Peter Valent , Alberto Orfao , Stefan Kubicek , Philipp Staber , Torsten Haferlach , Michael Deininger , Karoline Kollmann , Thomas Lion , Irene Virgolini , Georg Winter , Oliver Hantschel , Lukas Kenner , Johannes Zuber , Florian Grebien , Richard Moriggl , Gregor Hoermann , Olivier Hermine , Michael Andreeff , Christoph Bock , Tariq Mughal , Stefan N Constantinescu , Robert Kralovics , Veronika Sexl , Radek Skoda , Giulio Superti-Furga , Ulrich Jäger

STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.

Cytokine
Avec: Doris Kaltenecker , Madeleine Themanns , Kristina M Mueller , Katrin Spirk , Nicole Golob-Schwarzl , Katrin Friedbichler , Lukas Kenner , Johannes Haybaeck , Richard Moriggl

Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression.

Cytokine
Avec: Doris Kaltenecker , Madeleine Themanns , Kristina M Mueller , Katrin Spirk , Tobias Suske , Olaf Merkel , Lukas Kenner , Andreia Luís , Andrey Kozlov , Johannes Haybaeck , Mathias Müller , Xiaonan Han , Richard Moriggl

STAT3β is a tumor suppressor in acute myeloid leukemia.

Blood advances
Avec: Petra Aigner , Tatsuaki Mizutani , Jaqueline Horvath , Thomas Eder , Stefan Heber , Karin Lind , Valentin Just , Herwig P Moll , Assa Yeroslaviz , Michael J M Fischer , Lukas Kenner , Balázs Győrffy , Heinz Sill , Florian Grebien , Richard Moriggl , Emilio Casanova , Dagmar Stoiber

JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression.

International journal of cancer
Avec: Julian Mohrherr , Marcel Haber , Kristina Breitenecker , Petra Aigner , Stefan Moritsch , Viktor Voronin , Robert Eferl , Richard Moriggl , Dagmar Stoiber , Balázs Győrffy , Luka Brcic , Viktória László , Balázs Döme , Judit Moldvay , Katalin Dezső , Martin Bilban , Helmut Popper , Herwig P Moll , Emilio Casanova

Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival.

Biochimica et biophysica acta. Molecular basis of disease
Avec: Florian Kleinegger , Eva Hofer , Christina Wodlej , Nicole Golob-Schwarzl , Anna Maria Birkl-Toeglhofer , Alexander Stallinger , Johannes Petzold , Anna Orlova , Stefanie Krassnig , Robert Reihs , Tobias Niedrist , Harald Mangge , Young Nyun Park , Michael Thalhammer , Ariane Aigelsreiter , Sigurd Lax , Christoph Garbers , Peter Fickert , Stefan Rose-John , Richard Moriggl , Beate Rinner , Johannes Haybaeck

Targeting STAT3 and STAT5 in Cancer.

Cancers
Avec: Elvin D de Araujo , György M Keserű , Patrick T Gunning , Richard Moriggl

STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue.

Molecular metabolism
Avec: Doris Kaltenecker , Katrin Spirk , Frank Ruge , Florian Grebien , Marco Herling , Anne Rupprecht , Lukas Kenner , Elena E Pohl , Kristina M Mueller , Richard Moriggl

Down-regulation of A20 promotes immune escape of lung adenocarcinomas.

Science translational medicine
Avec: Kristina Breitenecker , Monika Homolya , Andreea C Luca , Veronika Lang , Christoph Trenk , Georg Petroczi , Julian Mohrherr , Jaqueline Horvath , Stefan Moritsch , Lisa Haas , Margarita Kurnaeva , Robert Eferl , Dagmar Stoiber , Richard Moriggl , Martin Bilban , Anna C Obenauf , Christiane Ferran , Balazs Dome , Viktoria Laszlo , Balázs Győrffy , Katalin Dezso , Judit Moldvay , Emilio Casanova , Herwig P Moll

A Recurrent

Cancers
Avec: Matthias Kieslinger , Alexander Swoboda , Nina Kramer , Patricia Freund , Barbara Pratscher , Heidi A Neubauer , Ralf Steinborn , Birgitt Wolfesberger , Andrea Fuchs-Baumgartinger , Richard Moriggl , Iwan A Burgener

The Diverse Roles of γδ T Cells in Cancer: From Rapid Immunity to Aggressive Lymphoma.

Cancers
Avec: Susann Schönefeldt , Tamara Wais , Marco Herling , Satu Mustjoki , Vasileios Bekiaris , Richard Moriggl , Heidi A Neubauer

Structural and mutational analysis of member-specific STAT functions.

Biochimica et biophysica acta. General subjects
Avec: Fettah Erdogan , Abdul K Qadree , Tudor B Radu , Anna Orlova , Elvin D de Araujo , Johan Israelian , Peter Valent , Satu M Mustjoki , Marco Herling , Richard Moriggl , Patrick T Gunning

Medicinal chemistry advances in targeting class I histone deacetylases.

Exploration of targeted anti-tumor therapy
Avec: Diaaeldin I Abdallah , Elvin D de Araujo , Naman H Patel , Lina S Hasan , Richard Moriggl , Oliver H Krämer , Patrick T Gunning

Réseau de co-auteurs

Richard Moriggl 60 collaborations
Lukas Kenner 19 collaborations
Heidi A Neubauer 17 collaborations
Anna Orlova 16 collaborations
Patrick T Gunning 15 collaborations
Elvin D de Araujo 13 collaborations
Peter Valent 11 collaborations
Florian Grebien 10 collaborations
Marco Herling 10 collaborations
Tobias Suske 9 collaborations
Michaela Schlederer 8 collaborations
Barbara Maurer 8 collaborations
Gregor Hoermann 8 collaborations
Dagmar Stoiber 7 collaborations
Veronika Sexl 7 collaborations
Olaf Merkel 7 collaborations
Fritz Aberger 6 collaborations
Birgit Strobl 6 collaborations
Mathias Müller 6 collaborations
Jan Pencik 5 collaborations
Daniel Pölöske 5 collaborations
Bettina Wingelhofer 5 collaborations
Christina Sternberg 5 collaborations
Stefan Kubicek 5 collaborations
Christoph Bock 5 collaborations
Robert Eferl 5 collaborations
Doris Kaltenecker 5 collaborations
Katrin Spirk 5 collaborations
Johannes Haybaeck 5 collaborations
Harini Nivarthi 4 collaborations
Xiaonan Han 4 collaborations
Fettah Erdogan 4 collaborations
Pimyupa Manaswiyoungkul 4 collaborations
Johan Israelian 4 collaborations
Simone Tangermann 4 collaborations
Thomas Rülicke 4 collaborations
Jaqueline Horvath 4 collaborations
Johannes Schmoellerl 4 collaborations
Christoph Kornauth 4 collaborations
Suzanne D Turner 4 collaborations
Helena Sorger 4 collaborations
Satu Mustjoki 4 collaborations
Gerda Egger 4 collaborations
Ayah Abdeldayem 3 collaborations
Ha T T Pham 3 collaborations
Helmut Dolznig 3 collaborations
Hyuk-Soo Seo 3 collaborations
Sirano Dhe-Paganon 3 collaborations
Emir Hadzijusufovic 3 collaborations
Thomas Krausgruber 3 collaborations
Tania Brandstoetter 3 collaborations
Wolfgang R Sperr 3 collaborations
Sabine Lagger 3 collaborations
Madeleine Themanns 3 collaborations
Thomas Eder 3 collaborations
Ha Thi Thanh Pham 3 collaborations
Gabriele Manhart 3 collaborations
Johannes Zuber 3 collaborations
Nicole Prutsch 3 collaborations
Tanja Limberger 3 collaborations
Astrid Aufinger 3 collaborations
Peter Wolf 3 collaborations
Ulrich Jäger 3 collaborations
Takaomi Sanda 3 collaborations
Dávid Bajusz 3 collaborations
György M Keserű 3 collaborations
Abootaleb Sedighi 3 collaborations
Oliver H Krämer 3 collaborations
Torsten Haferlach 3 collaborations
Caroline Lassnig 3 collaborations
Robert Kralovics 3 collaborations
Gary Tin 3 collaborations
Georg Greiner 3 collaborations
Nicole Golob-Schwarzl 3 collaborations
Satu M Mustjoki 3 collaborations
Susann Schönefeldt 3 collaborations
Kristina M Mueller 3 collaborations
Herwig P Moll 3 collaborations
Balázs Győrffy 3 collaborations
Emilio Casanova 3 collaborations
Alexander Lercher 2 collaborations
Hatoon Baazim 2 collaborations
Benedikt Agerer 2 collaborations
Lindsay Kosack 2 collaborations
Keiryn L Bennett 2 collaborations
Andreas Bergthaler 2 collaborations
Yasir S Raouf 2 collaborations
Stefan N Constantinescu 2 collaborations
Mario Mikula 2 collaborations
Patricia Freund 2 collaborations
Hai-Bin Ruan 2 collaborations
Abdul K Qadree 2 collaborations
Auke Boersma 2 collaborations
Alexander Swoboda 2 collaborations
Valeria Poli 2 collaborations
Markus Hengstschläger 2 collaborations
Reinhard Grausenburger 2 collaborations
Michaela Prchal-Murphy 2 collaborations
Vanessa M Knab 2 collaborations
Matthias Farlik 2 collaborations
Florian Halbritter 2 collaborations
Karoline Kollmann 2 collaborations
William Tse 2 collaborations
Selina Troester 2 collaborations
Jessica Ebner 2 collaborations
Elisabeth Gurnhofer 2 collaborations
Huan Chang Liang 2 collaborations
Simone Roos 2 collaborations
Lawren C Wu 2 collaborations
Ingrid Simonitsch-Klupp 2 collaborations
Andrea Alvarez-Hernandez 2 collaborations
Dario A Leone 2 collaborations
Jasmin Svinka 2 collaborations
Nitesh Shirsath 2 collaborations
Thomas Hielscher 2 collaborations
Philipp B Staber 2 collaborations
Giorgio G Inghirami 2 collaborations
A Thomas Look 2 collaborations
Vincent Goffin 2 collaborations
Andreia Luís 2 collaborations
Christina Wagner 2 collaborations
Nabanita Nawar 2 collaborations
Olasunkanmi O Olaoye 2 collaborations
Tudor B Radu 2 collaborations
Tero Aittokallio 2 collaborations
Karl Sotlar 2 collaborations
Hans-Peter Horny 2 collaborations
Michel Arock 2 collaborations
Katrin Meissl 2 collaborations
Sabine Macho-Maschler 2 collaborations
Petra Kodajova 2 collaborations
Monika Oberhuber 2 collaborations
Ines Garces de Los Fayos Alonso 2 collaborations
Felix Sternberg 2 collaborations
Boris Tichy 2 collaborations
Sarka Pospisilova 2 collaborations
Thomas Kolbe 2 collaborations
Nina Kramer 2 collaborations
Matteo Pecoraro 2 collaborations
Karolína Trachtová 2 collaborations
Brigitte Hantusch 2 collaborations
Marta Surbek 2 collaborations
Olivier Hermine 2 collaborations
Roman Fleck 2 collaborations
Ellen Heitzer 2 collaborations
Cecile Philippe 2 collaborations
Osman Aksoy 2 collaborations
Nadine Witzeneder 2 collaborations
Elena E Pohl 2 collaborations
Adam Varady 2 collaborations
Stefan Rose-John 2 collaborations
Ali A Moazzami 2 collaborations
David M Heery 2 collaborations
Marcus Hacker 2 collaborations
Jisung Park 2 collaborations
Vasileios Bekiaris 2 collaborations
Stefanie Krassnig 2 collaborations
Andrea Poelzl 2 collaborations
Mathias Mueller 2 collaborations
Elvin Dominic de Araujo 2 collaborations
Patrick Thomas Gunning 2 collaborations
Myint Myat Khine Aung 2 collaborations
Michael Andreeff 2 collaborations
Frank Ruge 2 collaborations
Diaaeldin I Abdallah 2 collaborations
Petra Aigner 2 collaborations
Julian Mohrherr 2 collaborations
Kristina Breitenecker 2 collaborations
Stefan Moritsch 2 collaborations
Judit Moldvay 2 collaborations
Martin Bilban 2 collaborations
Anannya Bhattacharya 1 collaboration
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Beate Rinner 1 collaboration
Anne Rupprecht 1 collaboration
Monika Homolya 1 collaboration
Andreea C Luca 1 collaboration
Veronika Lang 1 collaboration
Christoph Trenk 1 collaboration
Georg Petroczi 1 collaboration
Lisa Haas 1 collaboration
Margarita Kurnaeva 1 collaboration
Anna C Obenauf 1 collaboration
Christiane Ferran 1 collaboration
Balazs Dome 1 collaboration
Viktoria Laszlo 1 collaboration
Katalin Dezso 1 collaboration
Matthias Kieslinger 1 collaboration
Barbara Pratscher 1 collaboration
Ralf Steinborn 1 collaboration
Birgitt Wolfesberger 1 collaboration
Andrea Fuchs-Baumgartinger 1 collaboration
Iwan A Burgener 1 collaboration
Tamara Wais 1 collaboration
Naman H Patel 1 collaboration
Lina S Hasan 1 collaboration