Michael Andreeff

Affiliations
  • Department of Leukemia, Division of Cancer Medicine, and.

Publications (98)

Outcomes of older patients with NPM1-mutated AML: current treatments and the promise of venetoclax-based regimens.

Blood advances
Avec: Curtis A Lachowiez , Sanam Loghavi , Tapan M Kadia , Naval Daver , Gautam Borthakur , Naveen Pemmaraju , Kiran Naqvi , Yesid Alvarado , Musa Yilmaz , Nicholas Short , Maro Ohanian , Sherry R Pierce , Keyur P Patel , Wei Qiao , Jing Ning , Koji Sasaki , Koichi Takahashi , Elias Jabbour , Michael Andreeff , Farhad Ravandi , Hagop M Kantarjian , Marina Konopleva , Courtney D DiNardo

Bone marrow niches in haematological malignancies.

Nature reviews. Cancer
Avec: Simón Méndez-Ferrer , Dominique Bonnet , David P Steensma , Robert P Hasserjian , Irene M Ghobrial , John G Gribben , Michael Andreeff , Daniela S Krause

Combined inhibition of MDM2 and BCR-ABL1 tyrosine kinase targets chronic myeloid leukemia stem/progenitor cells in a murine model.

Haematologica
Avec: Bing Z Carter , Po Yee Mak , Hong Mu , Xiangmeng Wang , Wenjing Tao , Duncan H Mak , Elisha J Dettman , Michael Cardone , Oleg Zernovak , Takahiko Seki , Michael Andreeff

BETP degradation simultaneously targets acute myelogenous leukemia stem cells and the microenvironment.

The Journal of clinical investigation
Avec: Sujan Piya , Hong Mu , Seemana Bhattacharya , Philip L Lorenzi , R Eric Davis , Teresa McQueen , Vivian Ruvolo , Natalia Baran , Zhiqiang Wang , Yimin Qian , Craig M Crews , Marina Konopleva , Jo Ishizawa , M James You , Hagop Kantarjian , Michael Andreeff , Gautam Borthakur

Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia.

Blood
Avec: Jan A Burger , Mariela Sivina , Nitin Jain , Ekaterina Kim , Tapan Kadia , Zeev Estrov , Graciela M Nogueras-Gonzalez , Xuelin Huang , Jeffrey Jorgensen , Jianling Li , Mei Cheng , Fong Clow , Maro Ohanian , Michael Andreeff , Thomas Mathew , Philip Thompson , Hagop Kantarjian , Susan O'Brien , William G Wierda , Alessandra Ferrajoli , Michael J Keating

Correction: Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1.

Oncotarget
Avec: Kazumasa Sekihara , Kaori Saitoh , Lina Han , Stefan Ciurea , Shinichi Yamamoto , Mika Kikkawa , Saiko Kazuno , Hikari Taka , Naoko Kaga , Hajime Arai , Takashi Miida , Michael Andreeff , Marina Konopleva , Yoko Tabe

High-throughput proteomic profiling reveals mechanisms of action of AMG925, a dual FLT3-CDK4/6 kinase inhibitor targeting AML and AML stem/progenitor cells.

Annals of hematology
Avec: Zhihong Zeng , Charlie Ly , Naval Daver , Jorge Cortes , Hagop M Kantarjian , Michael Andreeff , Marina Konopleva

Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 inhibitors.

Blood cancer discovery
Avec: Ahmad S Alotaibi , Musa Yilmaz , Rashmi Kanagal-Shamanna , Sanam Loghavi , Tapan M Kadia , Courtney D DiNardo , Gautam Borthakur , Marina Konopleva , Sherry A Pierce , Sa A Wang , Guilin Tang , Veronica Guerra , Bachar Samra , Naveen Pemmaraju , Elias Jabbour , Nicholas J Short , Ghayas C Issa , Maro Ohanian , Guillermo Garcia-Manero , Kapil N Bhalla , Keyur P Patel , Koichi Takahashi , Michael Andreeff , Jorge E Cortes , Hagop M Kantarjian , Farhad Ravandi , Naval Daver

Hypomethylating agent and venetoclax with FLT3 inhibitor "triplet" therapy in older/unfit patients with FLT3 mutated AML.

Blood cancer journal
Avec: Musa Yilmaz , Hagop Kantarjian , Nicholas J Short , Patrick Reville , Marina Konopleva , Tapan Kadia , Courtney DiNardo , Gautam Borthakur , Naveen Pemmaraju , Abhishek Maiti , Elias Jabbour , Nitin Jain , Ghayas Issa , Koichi Takahashi , Koji Sasaki , Maro Ohanian , Sherry Pierce , Guillin Tang , Sanam Loghavi , Keyur Patel , Sa A Wang , Guillermo Garcia-Manero , Michael Andreeff , Farhad Ravandi , Naval Daver

Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic-Resistant AML and AML Stem Cells.

Molecular cancer therapeutics
Avec: Bing Z Carter , Po Yee Mak , Wenjing Tao , Qi Zhang , Vivian Ruvolo , Vinitha M Kuruvilla , Xiangmeng Wang , Duncan H Mak , Venkata L Battula , Marina Konopleva , Elias J Jabbour , Paul E Hughes , Xiaoyue Chen , Phuong K Morrow , Michael Andreeff

Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production.

Blood
Avec: Jong Bok Lee , Dilshad H Khan , Rose Hurren , Mingjing Xu , Yoosu Na , Hyeonjeong Kang , Sara Mirali , Xiaoming Wang , Marcela Gronda , Yulia Jitkova , Neil MacLean , Andrea Arruda , Zoe Alaniz , Marina Y Konopleva , Michael Andreeff , Mark D Minden , Li Zhang , Aaron D Schimmer

Phase II study of azacitidine with pembrolizumab in patients with intermediate-1 or higher-risk myelodysplastic syndrome.

British journal of haematology
Avec: Kelly S Chien , Kunhwa Kim , Graciela M Nogueras-Gonzalez , Gautam Borthakur , Kiran Naqvi , Naval G Daver , Guillermo Montalban-Bravo , Jorge E Cortes , Courtney D DiNardo , Elias Jabbour , Yesid Alvarado , Michael Andreeff , Prithviraj Bose , Nitin Jain , Tapan M Kadia , Xuelin Huang , Kimberly B Sheppard , Cheri Klingner-Winton , Sherry A Pierce , Xiao Qin Dong , Kelly A Soltysiak , Hagop M Kantarjian , Guillermo Garcia-Manero

Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition.

Blood advances
Avec: Kaori Saito , Qi Zhang , Haeun Yang , Kotoko Yamatani , Tomohiko Ai , Vivian Ruvolo , Natalia Baran , Tianyu Cai , Helen Ma , Rodrigo Jacamo , Vinitha Kuruvilla , Junichi Imoto , Sonoko Kinjo , Kazuho Ikeo , Kaori Moriya , Koya Suzuki , Takashi Miida , Yong-Mi Kim , Christopher P Vellano , Michael Andreeff , Joseph R Marszalek , Yoko Tabe , Marina Konopleva

Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.

Signal transduction and targeted therapy
Avec: Qi Zhang , Bridget Riley-Gillis , Lina Han , Yannan Jia , Alessia Lodi , Haijiao Zhang , Saravanan Ganesan , Rongqing Pan , Sergej N Konoplev , Shannon R Sweeney , Jeremy A Ryan , Yulia Jitkova , Kenneth Dunner , Shaun E Grosskurth , Priyanka Vijay , Sujana Ghosh , Charles Lu , Wencai Ma , Stephen Kurtz , Vivian R Ruvolo , Helen Ma , Connie C Weng , Cassandra L Ramage , Natalia Baran , Ce Shi , Tianyu Cai , Richard Eric Davis , Venkata L Battula , Yingchang Mi , Jing Wang , Courtney D DiNardo , Michael Andreeff , Jeffery W Tyner , Aaron Schimmer , Anthony Letai , Rose Ann Padua , Carlos E Bueso-Ramos , Stefano Tiziani , Joel Leverson , Relja Popovic , Marina Konopleva

Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML.

Blood advances
Avec: Ghayas C Issa , Aram Bidikian , Sangeetha Venugopal , Marina Konopleva , Courtney D DiNardo , Tapan M Kadia , Gautam Borthakur , Elias Jabbour , Naveen Pemmaraju , Musa Yilmaz , Nicholas J Short , Abhishek Maiti , Koji Sasaki , Lucia Masarova , Sherry Pierce , Koichi Takahashi , Guilin Tang , Sanam Loghavi , Keyur Patel , Michael Andreeff , Kapil Bhalla , Guillermo Garcia-Manero , Farhad Ravandi , Hagop Kantarjian , Naval Daver

A phase 1/2 study of azacitidine, venetoclax and pevonedistat in newly diagnosed secondary AML and in MDS or CMML after failure of hypomethylating agents.

Journal of hematology & oncology
Avec: Nicholas J Short , Muharrem Muftuoglu , Faustine Ong , Lewis Nasr , Walid Macaron , Guillermo Montalban-Bravo , Yesid Alvarado , Mahesh Basyal , Naval Daver , Courtney D Dinardo , Gautam Borthakur , Nitin Jain , Maro Ohanian , Elias Jabbour , Ghayas C Issa , Wei Qiao , Xuelin Huang , Rashmi Kanagal-Shamanna , Keyur P Patel , Prithviraj Bose , Farhad Ravandi , Ricardo Delumpa , Regina Abramova , Guillermo Garcia-Manero , Michael Andreeff , Jorge Cortes , Hagop Kantarjian

Enhanced

Science advances
Avec: Yuki Nishida , Jo Ishizawa , Edward Ayoub , Rafael Heinz Montoya , Lauren B Ostermann , Muharrem Muftuoglu , Vivian R Ruvolo , Tallie Patsilevas , Darah A Scruggs , Shayaun Khazaei , Po Yee Mak , Wenjing Tao , Bing Z Carter , Steffen Boettcher , Benjamin L Ebert , Naval G Daver , Marina Konopleva , Takahiko Seki , Kensuke Kojima , Michael Andreeff

Early mortality in acute myeloid leukemia with KMT2A rearrangement is associated with high risk of bleeding and disseminated intravascular coagulation.

Cancer
Avec: Daniel Nguyen , Hagop M Kantarjian , Nicholas J Short , Wei Qiao , Jing Ning , Branko Cuglievan , Naval G Daver , Courtney D DiNardo , Elias J Jabbour , Tapan M Kadia , Gautam Borthakur , Guillermo Garcia-Manero , Marina Y Konopleva , Michael Andreeff , Farhad Ravandi-Kashani , Koji Sasaki , Ghayas C Issa

Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.

Cancer cell
Avec: Jo Ishizawa , Sarah F Zarabi , R Eric Davis , Ondrej Halgas , Takenobu Nii , Yulia Jitkova , Ran Zhao , Jonathan St-Germain , Lauren E Heese , Grace Egan , Vivian R Ruvolo , Samir H Barghout , Yuki Nishida , Rose Hurren , Wencai Ma , Marcela Gronda , Todd Link , Keith Wong , Mark Mabanglo , Kensuke Kojima , Gautam Borthakur , Neil MacLean , Man Chun John Ma , Andrew B Leber , Mark D Minden , Walid Houry , Hagop Kantarjian , Martin Stogniew , Brian Raught , Emil F Pai , Aaron D Schimmer , Michael Andreeff

CXCR4 Inhibition Enhances Efficacy of FLT3 Inhibitors in FLT3-Mutated AML Augmented by Suppressed TGF-b Signaling.

Cancers
Avec: Bo-Reum Kim , Seung-Hyun Jung , A-Reum Han , Gyeongsin Park , Hee-Je Kim , Bin Yuan , Venkata Lokesh Battula , Michael Andreeff , Marina Konopleva , Yeun-Jun Chung , Byung-Sik Cho

10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial.

The Lancet. Haematology
Avec: Courtney D DiNardo , Abhishek Maiti , Caitlin R Rausch , Naveen Pemmaraju , Kiran Naqvi , Naval G Daver , Tapan M Kadia , Gautam Borthakur , Maro Ohanian , Yesid Alvarado , Ghayas C Issa , Guillermo Montalban-Bravo , Nicholas J Short , Musa Yilmaz , Prithviraj Bose , Elias J Jabbour , Koichi Takahashi , Jan A Burger , Guillermo Garcia-Manero , Nitin Jain , Steven M Kornblau , Philip A Thompson , Zeev Estrov , Lucia Masarova , Koji Sasaki , Srdan Verstovsek , Alessandra Ferrajoli , William G Weirda , Sa A Wang , Sergej Konoplev , Zhining Chen , Sherry A Pierce , Jing Ning , Wei Qiao , Farhad Ravandi , Michael Andreeff , John S Welch , Hagop M Kantarjian , Marina Y Konopleva

Updates on the hematologic tumor microenvironment and its therapeutic targeting.

Haematologica
Avec: Dorian Forte , Daniela S Krause , Michael Andreeff , Dominique Bonnet , Simón Méndez-Ferrer

TAM kinases as regulators of cell death.

Biochimica et biophysica acta. Molecular cell research
Avec: Sean M Post , Michael Andreeff , Courtney DiNardo , Joseph D Khoury , Peter P Ruvolo

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.

International journal of molecular sciences
Avec: Petra Gorombei , Fabien Guidez , Saravanan Ganesan , Mathieu Chiquet , Andrea Pellagatti , Laure Goursaud , Nilgun Tekin , Stephanie Beurlet , Satyananda Patel , Laura Guerenne , Carole Le Pogam , Niclas Setterblad , Pierre de la Grange , Christophe LeBoeuf , Anne Janin , Maria-Elena Noguera , Laure Sarda-Mantel , Pascale Merlet , Jacqueline Boultwood , Marina Konopleva , Michael Andreeff , Robert West , Marika Pla , Lionel Adès , Pierre Fenaux , Patricia Krief , Christine Chomienne , Nader Omidvar , Rose Ann Padua

Correction: Discovery and clinical introduction of first-in-class imipridone ONC201.

Oncotarget
Avec: Joshua E Allen , C Leah B Kline , Varun V Prabhu , Jessica Wagner , Jo Ishizawa , Neel Madhukar , Avital Lev , Marie Baumeister , Lanlan Zhou , Amriti Lulla , Martin Stogniew , Lee Schalop , Cyril Benes , Howard L Kaufman , Richard S Pottorf , B Rao Nallaganchu , Gary L Olson , Fahd Al-Mulla , Madeleine Duvic , Gen Sheng Wu , David T Dicker , Mala K Talekar , Bora Lim , Olivier Elemento , Wolfgang Oster , Joseph Bertino , Keith Flaherty , Michael L Wang , Gautam Borthakur , Michael Andreeff , Mark Stein , Wafik S El-Deiry

Bone marrow stromal cells induce an ALDH+ stem cell-like phenotype and enhance therapy resistance in AML through a TGF-β-p38-ALDH2 pathway.

PloS one
Avec: Bin Yuan , Fouad El Dana , Stanley Ly , Yuanqing Yan , Vivian Ruvolo , Elizabeth J Shpall , Marina Konopleva , Michael Andreeff , Venkata Lokesh Battula

BL-8040 CXCR4 antagonist is safe and demonstrates antileukemic activity in combination with cytarabine for the treatment of relapsed/refractory acute myelogenous leukemia: An open-label safety and efficacy phase 2a study.

Cancer
Avec: Gautam Borthakur , Yishai Ofran , Martin S Tallman , James Foran , Geoffrey L Uy , John F DiPersio , Margaret M Showel , Avichai Shimoni , Arnon Nagler , Jacob M Rowe , Jessica K Altman , Michal Abraham , Amnon Peled , Stephen Shaw , Osnat Bohana-Kashtan , Ella Sorani , Yaron Pereg , Adam Foley-Comer , Galia Oberkovitz , Tzipi M Lustig , Irit Glicko-Kabir , Arnon Aharon , Abi Vainstein-Haras , Shaul E Kadosh , Emil Samara , Ahmed N Al-Rawi , Naveen Pemmaraju , Carlos Bueso-Ramos , Jorge E Cortes , Michael Andreeff

Outcomes with sequential FLT3-inhibitor-based therapies in patients with AML.

Journal of hematology & oncology
Avec: Musa Yilmaz , Mansour Alfayez , Courtney D DiNardo , Gautam Borthakur , Tapan M Kadia , Marina Y Konopleva , Sanam Loghavi , Rashmi Kanagal-Shamanna , Keyur P Patel , Elias J Jabbour , Guillermo Garcia-Manero , Naveen Pemmaraju , Sherry A Pierce , Issa Ghayas , Nicholas J Short , Guillermo Montalban-Bravo , Koichi Takahashi , Rita Assi , Ahmad S Alotaibi , Maro Ohanian , Michael Andreeff , Jorge E Cortes , Hagop M Kantarjian , Farhad Ravandi , Naval G Daver

Loss of expression of both miR-15/16 loci in CML transition to blast crisis.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Francesca Lovat , Pierluigi Gasparini , Giovanni Nigita , Karilyn Larkin , John C Byrd , Mark D Minden , Michael Andreeff , Bing Z Carter , Carlo M Croce

Extended live-cell barcoding approach for multiplexed mass cytometry.

Scientific reports
Avec: Muharrem Muftuoglu , Li Li , Shaoheng Liang , Duncan Mak , Angelique J Lin , Junxiang Fang , Jared K Burks , Ken Chen , Michael Andreeff

A phase 1b/2 study of azacitidine with PD-L1 antibody avelumab in relapsed/refractory acute myeloid leukemia.

Cancer
Avec: Kapil Saxena , Shelley M Herbrich , Naveen Pemmaraju , Tapan M Kadia , Courtney D DiNardo , Gautam Borthakur , Sherry A Pierce , Elias Jabbour , Sa A Wang , Carlos Bueso-Ramos , Sanam Loghavi , Guillin Tang , Cora M Cheung , Lynette Alexander , Steven Kornblau , Michael Andreeff , Guillermo Garcia-Manero , Farhad Ravandi , Marina Y Konopleva , Naval Daver

Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia.

Nature communications
Avec: Natalia Baran , Alessia Lodi , Yogesh Dhungana , Shelley Herbrich , Meghan Collins , Shannon Sweeney , Renu Pandey , Anna Skwarska , Shraddha Patel , Mathieu Tremblay , Vinitha Mary Kuruvilla , Antonio Cavazos , Mecit Kaplan , Marc O Warmoes , Diogo Troggian Veiga , Ken Furudate , Shanti Rojas-Sutterin , Andre Haman , Yves Gareau , Anne Marinier , Helen Ma , Karine Harutyunyan , May Daher , Luciana Melo Garcia , Gheath Al-Atrash , Sujan Piya , Vivian Ruvolo , Wentao Yang , Sriram Saravanan Shanmugavelandy , Ningping Feng , Jason Gay , Di Du , Jun J Yang , Fieke W Hoff , Marcin Kaminski , Katarzyna Tomczak , R Eric Davis , Daniel Herranz , Adolfo Ferrando , Elias J Jabbour , M Emilia Di Francesco , David T Teachey , Terzah M Horton , Steven Kornblau , Katayoun Rezvani , Guy Sauvageau , Mihai Gagea , Michael Andreeff , Koichi Takahashi , Joseph R Marszalek , Philip L Lorenzi , Jiyang Yu , Stefano Tiziani , Trang Hoang , Marina Konopleva

Mdm2/p53 levels in bone marrow mesenchymal stromal cells is essential for maintaining the hematopoietic niche in response to DNA damage.

Research square
Avec: Rasoul Pourebrahim , Rafael Heinz Montoya , Zoe Alaniz , Lauren Ostermann , Patrick P Lin , Bin Liu , Edward Ayoub , Jared K Burks , Michael Andreeff

Molecular Mechanisms of Ferroptosis and Updates of Ferroptosis Studies in Cancers and Leukemia.

Cells
Avec: Hiroki Akiyama , Bing Z Carter , Michael Andreeff , Jo Ishizawa

Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells.

Blood
Avec: Bing Z Carter , Po Yee Mak , Muharrem Muftuoglu , Wenjing Tao , Baozhen Ke , Jingqi Pei , Andrea D Bedoy , Lauren B Ostermann , Yuki Nishida , Sevinj Isgandarova , Mary Sobieski , Nghi Nguyen , Reid T Powell , Margarita Martinez-Moczygemba , Clifford Stephan , Mahesh Basyal , Naveen Pemmaraju , Steffen Boettcher , Benjamin L Ebert , Elizabeth J Shpall , Barbara Wallner , Robert A Morgan , Georgios I Karras , Ute M Moll , Michael Andreeff

Phase 1 dose escalation study of the MDM2 inhibitor milademetan as monotherapy and in combination with azacitidine in patients with myeloid malignancies.

Cancer medicine
Avec: Courtney D DiNardo , Rebecca Olin , Eunice S Wang , Barry Skikne , Joseph Rosenthal , Prasanna Kumar , Hiroyuki Sumi , Yoshiyuki Hizukuri , Ying Hong , Parul Patel , Takahiko Seki , Tao Duan , Arnaud Lesegretain , Michael Andreeff

The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and aurora kinases.

Leukemia & lymphoma
Avec: Guopan Yu , Weiguo Zhang , Mahesh Basyal , Yuki Nishida , Hideaki Mizumo , Charlie Ly , Hongying Zhang , William G Rice , Michael Andreeff

Menin inhibitors in pediatric acute leukemia: a comprehensive review and recommendations to accelerate progress in collaboration with adult leukemia and the international community.

Leukemia
Avec: Branko Cuglievan , Hagop Kantarjian , Jeffrey E Rubnitz , Todd M Cooper , C Michel Zwaan , Jessica A Pollard , Courtney D DiNardo , Tapan M Kadia , Erin Guest , Nicholas J Short , David McCall , Naval Daver , Cesar Nunez , Fadi G Haddad , Miriam Garcia , Kapil N Bhalla , Abhishek Maiti , Samanta Catueno , Warren Fiskus , Bing Z Carter , Amber Gibson , Michael Roth , Sajad Khazal , Priti Tewari , Hussein A Abbas , Wallace Bourgeois , Michael Andreeff , Neerav N Shukla , Danh D Truong , Jeremy Connors , Joseph A Ludwig , Janine Stutterheim , Elisabeth Salzer , Kristian L Juul-Dam , Koji Sasaki , Kris M Mahadeo , Sarah K Tasian , Gautam Borthakur , Samantha Dickson , Nitin Jain , Elias Jabbour , Soheil Meshinchi , Guillermo Garcia-Manero , Farhad Ravandi , Eytan M Stein , E Anders Kolb , Ghayas C Issa

Survivorship in AML - a landmark analysis on the outcomes of acute myelogenous leukemia patients after maintaining complete remission for at least 3 years.

Leukemia & lymphoma
Avec: Catherine Kendall Major , Hagop Kantarjian , Koji Sasaki , Gautam Borthakur , Tapan Kadia , Naveen Pemmaraju , Courtney DiNardo , Nicholas J Short , Naval Daver , Elias Jabbour , Richard Champlin , Guillermo Garcia-Manero , Marina Konopleva , Michael Andreeff , Steven Kornblau , William Wierda , Sherry Pierce , Farhad Ravandi , Jorge Cortes

Clinical value of event-free survival in acute myeloid leukemia.

Blood advances
Avec: Abhishek Maiti , Hagop M Kantarjian , Vinita Popat , Gautam Borthakur , Guillermo Garcia-Manero , Marina Y Konopleva , Courtney D DiNardo , Srdan Verstovsek , Michael Andreeff , Tapan M Kadia , Helen O Ajufo , Rohit V Goswamy , Carlos Blanco , Miguel Velasquez , Naval G Daver , Naveen Pemmaraju , Sherry R Pierce , William G Wierda , Steven M Kornblau , Farhad Ravandi , Jorge E Cortes

LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML.

Blood advances
Avec: Neil Beeharry , Sean Landrette , Sophia Gayle , Marylens Hernandez , Jeff E Grotzke , Peter R Young , Paul Beckett , Xuan Zhang , Bing Z Carter , Michael Andreeff , Stephanie Halene , Tian Xu , Jonathan Rothberg , Henri Lichenstein

Prognostic significance of baseline FLT3-ITD mutant allele level in acute myeloid leukemia treated with intensive chemotherapy with/without sorafenib.

American journal of hematology
Avec: Fevzi Yalniz , Iman Abou Dalle , Hagop Kantarjian , Gautam Borthakur , Tapan Kadia , Keyur Patel , Sanam Loghavi , Guillermo Garcia-Manero , Koji Sasaki , Naval Daver , Courtney DiNardo , Naveen Pemmaraju , Nicholas J Short , Musa Yilmaz , Prithviraj Bose , Kiran Naqvi , Sherry Pierce , Graciela M Nogueras González , Marina Konopleva , Michael Andreeff , Jorge Cortes , Farhad Ravandi

Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models.

Haematologica
Avec: Lina Han , Qi Zhang , Monique Dail , Ce Shi , Antonio Cavazos , Vivian R Ruvolo , Yang Zhao , Eugene Kim , Mohamed Rahmani , Duncan H Mak , Sha S Jin , Jun Chen , Darren C Phillips , Paul Bottecelli Koller , Rodrigo Jacamo , Jared K Burks , Courtney DiNardo , Naval Daver , Elias Jabbour , Jing Wang , Hagop M Kantarjian , Michael Andreeff , Steven Grant , Joel D Leverson , Deepak Sampath , Marina Konopleva

Effects of Positive End-Expiratory Pressure and Spontaneous Breathing Activity on Regional Lung Inflammation in Experimental Acute Respiratory Distress Syndrome.

Critical care medicine
Avec: Thomas Kiss , Thomas Bluth , Anja Braune , Robert Huhle , Axel Denz , Moritz Herzog , Johannes Herold , Luigi Vivona , Marco Millone , Alice Bergamaschi , Michael Andreeff , Martin Scharffenberg , Jakob Wittenstein , Marcos F Vidal Melo , Thea Koch , Patricia R M Rocco , Paolo Pelosi , Jörg Kotzerke , Marcelo Gama de Abreu

Janus kinase 2 variants associated with the transformation of myeloproliferative neoplasms into acute myeloid leukemia.

Cancer
Avec: Christopher B Benton , Prajwal C Boddu , Courtney D DiNardo , Prithviraj Bose , Feng Wang , Rita Assi , Naveen Pemmaraju , Devendra Kc , Sherry Pierce , Keyur Patel , Marina Konopleva , Farhad Ravandi , Guillermo Garcia-Manero , Tapan M Kadia , Jorge Cortes , Hagop M Kantarjian , Michael Andreeff , Srdan Verstovsek

XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53.

Journal of hematology & oncology
Avec: Manman Deng , Mingzhi Zhang , Zijun Y Xu-Monette , Lan V Pham , Alexandar Tzankov , Carlo Visco , Xiaosheng Fang , Govind Bhagat , Feng Zhu , Karen Dybkaer , April Chiu , Wayne Tam , Youli Zu , Eric D Hsi , William W L Choi , Jooryung Huh , Maurilio Ponzoni , Andrés J M Ferreri , Michael B Møller , Benjamin M Parsons , J Han van Krieken , Miguel A Piris , Jane N Winter , Fredrick Hagemeister , Lapo Alinari , Yong Li , Michael Andreeff , Bing Xu , Ken H Young

Prognostic and therapeutic impacts of mutant TP53 variant allelic frequency in newly diagnosed acute myeloid leukemia.

Blood advances
Avec: Nicholas J Short , Guillermo Montalban-Bravo , Hyunsoo Hwang , Jing Ning , Miguel J Franquiz , Rashmi Kanagal-Shamanna , Keyur P Patel , Courtney D DiNardo , Farhad Ravandi , Guillermo Garcia-Manero , Koichi Takahashi , Marina Konopleva , Naval Daver , Ghayas C Issa , Michael Andreeff , Hagop Kantarjian , Tapan M Kadia

Publisher Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.

Nature communications
Avec: Kiyomi Morita , Feng Wang , Katharina Jahn , Tianyuan Hu , Tomoyuki Tanaka , Yuya Sasaki , Jack Kuipers , Sanam Loghavi , Sa A Wang , Yuanqing Yan , Ken Furudate , Jairo Matthews , Latasha Little , Curtis Gumbs , Jianhua Zhang , Xingzhi Song , Erika Thompson , Keyur P Patel , Carlos E Bueso-Ramos , Courtney D DiNardo , Farhad Ravandi , Elias Jabbour , Michael Andreeff , Jorge Cortes , Kapil Bhalla , Guillermo Garcia-Manero , Hagop Kantarjian , Marina Konopleva , Daisuke Nakada , Nicholas Navin , Niko Beerenwinkel , P Andrew Futreal , Koichi Takahashi

Radiotherapy enhances uptake and efficacy of

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Avec: Antje Dietrich , Michael Andreeff , Lydia Koi , Ralf Bergmann , Maik Schubert , Lena Schreiner , Steffen Löck , Wiebke Sihver , Robert Freudenberg , Sandra Hering , Hans-Jürgen Pietzsch , Jörg Steinbach , Jörg Kotzerke , Michael Baumann , Mechthild Krause

A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia.

Molecular cell
Avec: Xi Shen , Rui Wang , Moon Jong Kim , Qianghua Hu , Chih-Chao Hsu , Jun Yao , Naeh Klages-Mundt , Yanyan Tian , Erica Lynn , Thomas F Brewer , Yilei Zhang , Banu Arun , Boyi Gan , Michael Andreeff , Shunichi Takeda , Junjie Chen , Jae-Il Park , Xiaobing Shi , Christopher J Chang , Sung Yun Jung , Jun Qin , Lei Li

Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and resensitizes acute myeloid leukemia to BCL-2 inhibition.

Haematologica
Avec: Bing Z Carter , Po Yee Mak , Wenjing Tao , Marc Warmoes , Philip L Lorenzi , Duncan Mak , Vivian Ruvolo , Lin Tan , Justin Cidado , Lisa Drew , Michael Andreeff

LGALS1 acts as a pro-survival molecule in AML.

Biochimica et biophysica acta. Molecular cell research
Avec: Peter P Ruvolo , Huaxian Ma , Vivian R Ruvolo , Xiaorui Zhang , Sean M Post , Michael Andreeff

Fatty Acid Metabolism, Bone Marrow Adipocytes, and AML.

Frontiers in oncology
Avec: Yoko Tabe , Marina Konopleva , Michael Andreeff

Prognostic value of measurable residual disease after venetoclax and decitabine in acute myeloid leukemia.

Blood advances
Avec: Abhishek Maiti , Courtney D DiNardo , Sa A Wang , Jeffrey Jorgensen , Tapan M Kadia , Naval G Daver , Nicholas J Short , Musa Yilmaz , Naveen Pemmaraju , Gautam Borthakur , Prithviraj Bose , Ghayas C Issa , Alessandra Ferrajoli , Elias J Jabbour , Nitin Jain , Guillermo Garcia-Manero , Maro Ohanian , Koichi Takahashi , Guillermo Montalban-Bravo , Lucia Masarova , Jan A Burger , Philip A Thompson , Srdan Verstovsek , Koji Sasaki , Michael Andreeff , Caitlin R Rausch , Kathryn S Montalbano , Sherry Pierce , Wei Qiao , Jing Ning , Hagop M Kantarjian , Marina Y Konopleva , Farhad Ravandi

Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements.

Blood cancer journal
Avec: Ghayas C Issa , Jabra Zarka , Koji Sasaki , Wei Qiao , Daewoo Pak , Jing Ning , Nicholas J Short , Fadi Haddad , Zhenya Tang , Keyur P Patel , Branko Cuglievan , Naval Daver , Courtney D DiNardo , Elias Jabbour , Tapan Kadia , Gautam Borthakur , Guillermo Garcia-Manero , Marina Konopleva , Michael Andreeff , Hagop M Kantarjian , Farhad Ravandi

Value of measurable residual disease monitoring in patients with acute promyelocytic leukemia in the era of frontline 'chemotherapy-free' therapy.

Leukemia & lymphoma
Avec: Jorge M Ramos Perez , Keyur P Patel , Sanam Loghavi , Guillermo Garcia-Manero , Gautam Borthakur , Elias Jabbour , William Wierda , Sherry Pierce , Mark Brandt , Steven Kornblau , Tapan Kadia , Naval Daver , Courtney D DiNardo , Nitin Jain , Musa Yilmaz , Nicholas Short , Srdan Verstovsek , Alessandra Ferrajoli , Michael Andreeff , Marina Konopleva , Daniel Rivera , David McCue , Hagop M Kantarjian , Farhad Ravandi

A multi-arm phase Ib/II study designed for rapid, parallel evaluation of novel immunotherapy combinations in relapsed/refractory acute myeloid leukemia.

Leukemia & lymphoma
Avec: Nicholas J Short , Gautam Borthakur , Naveen Pemmaraju , Courtney D Dinardo , Tapan M Kadia , Elias Jabbour , Marina Konopleva , Walid Macaron , Jing Ning , Junsheng Ma , Sherry Pierce , Yesid Alvarado , Koji Sasaki , Koichi Takahashi , Zeev Estrov , Lucia Masarova , Ghayas C Issa , Guillermo Montalban-Bravo , Michael Andreeff , Jan A Burger , Darla Miller , Lynette Alexander , Aung Naing , Guillermo Garcia-Manero , Farhad Ravandi , Naval Daver

Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models.

Frontiers in immunology
Avec: Hong Mu-Mosley , Lauren Ostermann , Muharrem Muftuoglu , Abishek Vaidya , Challice L Bonifant , Mireya Paulina Velasquez , Stephen Gottschalk , Michael Andreeff

Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial.

Blood
Avec: Naval G Daver , Monique Dail , Jacqueline S Garcia , Brian A Jonas , Karen W L Yee , Kevin R Kelly , Norbert Vey , Sarit Assouline , Gail J Roboz , Stefania Paolini , Daniel A Pollyea , Agostino Tafuri , Joseph M Brandwein , Arnaud Pigneux , Bayard L Powell , Pierre Fenaux , Rebecca L Olin , Giuseppe Visani , Giovanni Martinelli , Maika Onishi , Jue Wang , Weize Huang , Cherie Green , Marion G Ott , Wan-Jen Hong , Marina Y Konopleva , Michael Andreeff

Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia.

Cancer discovery
Avec: Christina Glytsou , Xufeng Chen , Emmanouil Zacharioudakis , Wafa Al-Santli , Hua Zhou , Bettina Nadorp , Soobeom Lee , Audrey Lasry , Zhengxi Sun , Dimitrios Papaioannou , Michael Cammer , Kun Wang , Tomasz Zal , Malgorzata Anna Zal , Bing Z Carter , Jo Ishizawa , Raoul Tibes , Aristotelis Tsirigos , Michael Andreeff , Evripidis Gavathiotis , Iannis Aifantis

A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative analysis.

Blood cancer journal
Avec: Jayastu Senapati , Muharrem Muftuoglu , Jo Ishizawa , Hussein A Abbas , Sanam Loghavi , Gautam Borthakur , Musa Yilmaz , Ghayas C Issa , Samuel I Dara , Mahesh Basyal , Li Li , Kiran Naqvi , Rasoul Pourebrahim , Elias J Jabbour , Steven M Kornblau , Nicholas J Short , Naveen Pemmaraju , Guillermo Garcia-Manero , Farhad Ravandi , Joseph Khoury , Naval Daver , Hagop M Kantarjian , Michael Andreeff , Courtney D DiNardo

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia.

Nature communications
Avec: Jessica Ebner , Johannes Schmoellerl , Martin Piontek , Gabriele Manhart , Selina Troester , Bing Z Carter , Heidi Neubauer , Richard Moriggl , Gergely Szakács , Johannes Zuber , Thomas Köcher , Michael Andreeff , Wolfgang R Sperr , Peter Valent , Florian Grebien

Outcome of 3q26.2/MECOM rearrangements in chronic myeloid leukemia.

International journal of hematology
Avec: Hiroki Akiyama , Hagop Kantarjian , Elias Jabbour , Ghayas Issa , Fadi G Haddad , Nicholas J Short , Shimin Hu , Jo Ishizawa , Michael Andreeff , Koji Sasaki

Age-specific induction of mutant p53 drives clonal hematopoiesis and acute myeloid leukemia in adult mice.

Cell reports. Medicine
Avec: Rasoul Pourebrahim , Rafael Heinz Montoya , Hiroki Akiyama , Lauren Ostermann , Shayuan Khazaei , Muharrem Muftuoglu , Natalia Baran , Ran Zhao , Tom Lesluyes , Bin Liu , Joseph D Khoury , Mihai Gagea , Peter Van Loo , Michael Andreeff

Protocol for monitoring clonal hematopoiesis in transgenic mouse models using multispectral imaging.

STAR protocols
Avec: Priyanka Khanna , Lauren B Ostermann , Shayaun Khazaei , Ran Zhao , Michael Andreeff , Rasoul Pourebrahim

A phase I/II study of the combination of quizartinib with azacitidine or low-dose cytarabine for the treatment of patients with acute myeloid leukemia and myelodysplastic syndrome.

Haematologica
Avec: Mahesh Swaminathan , Hagop M Kantarjian , Mark Levis , Veronica Guerra , Gautam Borthakur , Yesid Alvarado , Courtney D DiNardo , Tapan Kadia , Guillermo Garcia-Manero , Maro Ohanian , Naval Daver , Marina Konopleva , Naveen Pemmaraju , Alessandra Ferrajoli , Michael Andreeff , Nitin Jain , Zeev Estrov , Elias J Jabbour , William G Wierda , Sherry Pierce , Maria Rhona Pinsoy , Lianchun Xiao , Farhad Ravandi , Jorge E Cortes

Venetoclax Combined With FLAG-IDA Induction and Consolidation in Newly Diagnosed and Relapsed or Refractory Acute Myeloid Leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Avec: Courtney D DiNardo , Curtis A Lachowiez , Koichi Takahashi , Sanam Loghavi , Lianchun Xiao , Tapan Kadia , Naval Daver , Maria Adeoti , Nicholas J Short , Koji Sasaki , Sa Wang , Gautam Borthakur , Ghayas Issa , Abhishek Maiti , Yesid Alvarado , Naveen Pemmaraju , Guillermo Montalban Bravo , Lucia Masarova , Musa Yilmaz , Nitin Jain , Michael Andreeff , Elias Jabbour , Guillermo Garcia-Manero , Steven Kornblau , Farhad Ravandi , Marina Y Konopleva , Hagop M Kantarjian

Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions.

HemaSphere
Avec: Peter Valent , Alberto Orfao , Stefan Kubicek , Philipp Staber , Torsten Haferlach , Michael Deininger , Karoline Kollmann , Thomas Lion , Irene Virgolini , Georg Winter , Oliver Hantschel , Lukas Kenner , Johannes Zuber , Florian Grebien , Richard Moriggl , Gregor Hoermann , Olivier Hermine , Michael Andreeff , Christoph Bock , Tariq Mughal , Stefan N Constantinescu , Robert Kralovics , Veronika Sexl , Radek Skoda , Giulio Superti-Furga , Ulrich Jäger

Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia.

Leukemia
Avec: Takenobu Nii , Varun V Prabhu , Vivian Ruvolo , Neel Madhukar , Ran Zhao , Hong Mu , Lauren Heese , Yuki Nishida , Kensuke Kojima , Mathew J Garnett , Ultan McDermott , Cyril H Benes , Neil Charter , Sean Deacon , Olivier Elemento , Joshua E Allen , Wolfgang Oster , Martin Stogniew , Jo Ishizawa , Michael Andreeff

An ARC-Regulated IL1β/Cox-2/PGE2/β-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML.

Cancer research
Avec: Bing Z Carter , Po Yee Mak , Xiangmeng Wang , Wenjing Tao , Vivian Ruvolo , Duncan Mak , Hong Mu , Jared K Burks , Michael Andreeff

Measurement of relative lung perfusion with electrical impedance and positron emission tomography: an experimental comparative study in pigs.

British journal of anaesthesia
Avec: T Bluth , T Kiss , M Kircher , A Braune , C Bozsak , R Huhle , M Scharffenberg , M Herzog , J Roegner , P Herzog , L Vivona , M Millone , O Dössel , M Andreeff , T Koch , J Kotzerke , B Stender , M Gama de Abreu

LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML.

EBioMedicine
Avec: Peter P Ruvolo , Chenyue W Hu , Yihua Qiu , Vivian R Ruvolo , Robin L Go , Stefan E Hubner , Kevin R Coombes , Michael Andreeff , Amina A Qutub , Steven M Kornblau

The distribution of T-cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia.

Cancer
Avec: Patrick Williams , Sreyashi Basu , Guillermo Garcia-Manero , Christopher S Hourigan , Karolyn A Oetjen , Jorge E Cortes , Farhad Ravandi , Elias J Jabbour , Zainab Al-Hamal , Marina Konopleva , Jing Ning , Lianchun Xiao , Juliana Hidalgo Lopez , Steve M Kornblau , Michael Andreeff , Wilmer Flores , Carlos Bueso-Ramos , Jorge Blando , Pallavi Galera , Katherine R Calvo , Gheath Al-Atrash , James P Allison , Hagop M Kantarjian , Padmanee Sharma , Naval G Daver

Phase II trial of CPX-351 in patients with acute myeloid leukemia at high risk for induction mortality.

Leukemia
Avec: Ghayas C Issa , Hagop M Kantarjian , Lianchun Xiao , Jing Ning , Yesid Alvarado , Gautam Borthakur , Naval Daver , Courtney D DiNardo , Elias Jabbour , Prithviraj Bose , Nitin Jain , Tapan M Kadia , Kiran Naqvi , Naveen Pemmaraju , Koichi Takahashi , Srdan Verstovsek , Micheal Andreeff , Steven M Kornblau , Zeev Estrov , Alessandra Ferrajoli , Guillermo Garcia-Manero , Maro Ohanian , William G Wierda , Farhad Ravandi , Jorge E Cortes

DNA-PK inhibitor peposertib enhances p53-dependent cytotoxicity of DNA double-strand break inducing therapy in acute leukemia.

Scientific reports
Avec: Eric Haines , Yuki Nishida , Michael I Carr , Rafael Heinz Montoya , Lauren B Ostermann , Weiguo Zhang , Frank T Zenke , Andree Blaukat , Michael Andreeff , Lyubomir T Vassilev

Metabolic stress induces GD2

British journal of cancer
Avec: Appalaraju Jaggupilli , Stanley Ly , Khoa Nguyen , Vivek Anand , Bin Yuan , Fouad El-Dana , Yuanqing Yan , Zoe Arvanitis , Danthasinghe Waduge Badrajee Piyarathna , Nagireddy Putluri , Helen Piwnica-Worms , Henry Charles Manning , Michael Andreeff , V Lokesh Battula

[Treatment Planning and Dose Verification for Combined Internal and External Radiotherapy (CIERT)].

Nuklearmedizin. Nuclear medicine
Avec: Robert Freudenberg , Holger Hartmann , Michael Andreeff , Liane Oehme , Thomas Leichtner , Alexander Fischer , Timo Paulus , Mechthild Krause , Jörg Kotzerke

Therapeutic implications of menin inhibition in acute leukemias.

Leukemia
Avec: Ghayas C Issa , Farhad Ravandi , Courtney D DiNardo , Elias Jabbour , Hagop M Kantarjian , Michael Andreeff

Ganglioside GD2: a novel therapeutic target in triple-negative breast cancer.

Annals of the New York Academy of Sciences
Avec: Claire Shao , Vivek Anand , Michael Andreeff , Venkata Lokesh Battula

Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML.

Translational oncology
Avec: Kotoko Yamatani , Tomohiko Ai , Kaori Saito , Koya Suzuki , Atsushi Hori , Sonoko Kinjo , Kazuho Ikeo , Vivian Ruvolo , Weiguo Zhang , Po Yee Mak , Bogumil Kaczkowski , Hironori Harada , Kazuhiro Katayama , Yoshikazu Sugimoto , Jered Myslinski , Takashi Hato , Takashi Miida , Marina Konopleva , Yoshihide Hayashizaki , Bing Z Carter , Yoko Tabe , Michael Andreeff

In-depth analysis of SARS-CoV-2-specific T cells reveals diverse differentiation hierarchies in vaccinated individuals.

JCI insight
Avec: Li Li , Muharrem Muftuoglu , Shaoheng Liang , Mahesh Basyal , Jiangxing Lv , Mehmet Emin Akdogan , Ken Chen , Michael Andreeff , Christopher R Flowers , Simrit Parmar

Beyond BCL-2 Inhibition in Acute Myloid Leukemia: Other Approaches to Leverage the Apoptotic Pathway.

Clinical lymphoma, myeloma & leukemia
Avec: Abhishek Maiti , Bing Z Carter , Michael Andreeff , Marina Y Konopleva

Venetoclax combined with FLAG-IDA induction and consolidation in newly diagnosed acute myeloid leukemia.

American journal of hematology
Avec: Courtney D DiNardo , Curtis A Lachowiez , Koichi Takahashi , Sanam Loghavi , Tapan Kadia , Naval Daver , Lianchun Xiao , Maria Adeoti , Nicholas J Short , Koji Sasaki , Sa A Wang , Gautam Borthakur , Ghayas Issa , Abhishek Maiti , Yesid Alvarado , Naveen Pemmaraju , Guillermo Montalban Bravo , Lucia Masarova , Musa Yilmaz , Nitin Jain , Michael Andreeff , Guillermo Garcia-Manero , Steven Kornblau , Farhad Ravandi , Elias Jabbour , Marina Y Konopleva , Hagop M Kantarjian

Phase II Study of Venetoclax Added to Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Avec: Tapan M Kadia , Patrick K Reville , Xuemei Wang , Caitlin R Rausch , Gautam Borthakur , Naveen Pemmaraju , Naval G Daver , Courtney D DiNardo , Koji Sasaki , Ghayas C Issa , Maro Ohanian , Guillermo Montalban-Bravo , Nicholas J Short , Nitin Jain , Alessandra Ferrajoli , Kapil N Bhalla , Elias Jabbour , Koichi Takahashi , Rashmi Malla , Kelly Quagliato , Rashmi Kanagal-Shamanna , Uday R Popat , Michael Andreeff , Guillermo Garcia-Manero , Marina Y Konopleva , Farhad Ravandi , Hagop M Kantarjian

Azacitidine plus venetoclax in patients with high-risk myelodysplastic syndromes or chronic myelomonocytic leukaemia: phase 1 results of a single-centre, dose-escalation, dose-expansion, phase 1-2 study.

The Lancet. Haematology
Avec: Alexandre Bazinet , Faezeh Darbaniyan , Elias Jabbour , Guillermo Montalban-Bravo , Maro Ohanian , Kelly Chien , Tapan Kadia , Koichi Takahashi , Lucia Masarova , Nicholas Short , Yesid Alvarado , Musa Yilmaz , Farhad Ravandi , Michael Andreeff , Rashmi Kanagal-Shamanna , Irene Ganan-Gomez , Simona Colla , Wei Qiao , Xuelin Huang , Deborah McCue , Bailey Mirabella , Hagop Kantarjian , Guillermo Garcia-Manero

Clinical and molecular profiling of AML patients with chromosome 7 or 7q deletions in the context of

Leukemia & lymphoma
Avec: Hussein A Abbas , Edward Ayoub , Hanxiao Sun , Rashmi Kanagal-Shamanna , Nicholas J Short , Ghayas Issa , Musa Yilmaz , Sherry Pierce , Daniel Rivera , Brent Cham , Shane Wing , Ziyi Li , Danielle Hammond , Elias Jabbour , Gautam Borthakur , Guillermo Garcia-Manero , Michael Andreeff , Naval Daver , Tapan Kadia , Marina Konopleva , Courtney DiNardo , Farhad Ravandi

A phase two study of high dose blinatumomab in Richter's syndrome.

Leukemia
Avec: Philip A Thompson , Xianli Jiang , Pinaki Banerjee , Rafet Basar , Naveen Garg , Ken Chen , Mecit Kaplan , Vandana Nandivada , Ana Karen Nunez Cortes , Alessandra Ferrajoli , Michael J Keating , Christine B Peterson , Michael Andreeff , Katayoun Rezvani , William G Wierda

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy.

Haematologica
Avec: Weiguo Zhang , Guopan Yu , Hongying Zhang , Mahesh Basyal , Charlie Ly , Bin Yuan , Vivian Ruvolo , Sujan Piya , Seemana Bhattacharya , Qi Zhang , Gautam Borthakur , Venkata Battula , Marina Konopleva , William G Rice , Michael Andreeff

The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and Aurora kinases.

Research square
Avec: Guopan Yu , Weiguo Zhang , Hongying Zhang , Charlie Ly , Mahesh Basyal , William G Rice , Michael Andreeff

Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cells.

Haematologica
Avec: Yannan Jia , Lina Han , Cassandra L Ramage , Zhe Wang , Connie C Weng , Lei Yang , Simona Colla , Helen Ma , Weiguo Zhang , Michael Andreeff , Naval Daver , Nitin Jain , Naveen Pemmaraju , Kapil Bhalla , Satu Mustjoki , Peiyi Zhang , Guangrong Zheng , Daohong Zhou , Qi Zhang , Marina Konopleva

Determination of Radiation Exposure of Individuals in the Population by Patients after Radioiodine Therapy - Comparison of two Measurement Systems.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Avec: Holger Hartmann , Michael Andreeff , Jörg Claußnitzer , Jörg Kotzerke , Claudia Brogsitter

Venetoclax and Cobimetinib in Relapsed/Refractory AML: A Phase 1b Trial.

Clinical lymphoma, myeloma & leukemia
Avec: Marina Y Konopleva , Monique Dail , Naval G Daver , Jacqueline S Garcia , Brian A Jonas , Karen W L Yee , Kevin R Kelly , Norbert Vey , Sarit Assouline , Gail J Roboz , Stefania Paolini , Daniel A Pollyea , Agostino Tafuri , Joseph M Brandwein , Arnaud Pigneux , Bayard L Powell , Pierre Fenaux , Rebecca L Olin , Giuseppe Visani , Giovanni Martinelli , Maika Onishi , Jue Wang , Weize Huang , Diana Dunshee , Habib Hamidi , Marion G Ott , Wan-Jen Hong , Michael Andreeff

Inhibition of Oxidative Phosphorylation Reverses Bone Marrow Hypoxia Visualized in Imageable Syngeneic B-ALL Mouse Model.

Frontiers in oncology
Avec: Mateusz Rytelewski , Karine Harutyunyan , Natalia Baran , Saradhi Mallampati , M Anna Zal , Antonio Cavazos , Jason M Butler , Sergej Konoplev , Mirna El Khatib , Shane Plunkett , Joseph R Marszalek , Michael Andreeff , Tomasz Zal , Marina Konopleva

Phase 1 study of combinatorial sorafenib, G-CSF, and plerixafor treatment in relapsed/refractory, FLT3-ITD-mutated acute myelogenous leukemia patients.

American journal of hematology
Avec: Gautam Borthakur , Zhihong Zeng , Jorge E Cortes , Hsiang-Chun Chen , Xuelin Huang , Marina Konopleva , Farhad Ravandi , Tapan Kadia , Keyur P Patel , Naval Daver , Mary A Kelly , Teresa McQueen , Ru-Yiu Wang , Hagop Kantarjian , Michael Andreeff

MDM2 inhibition: an important step forward in cancer therapy.

Leukemia
Avec: Marina Konopleva , Giovanni Martinelli , Naval Daver , Cristina Papayannidis , Andrew Wei , Brian Higgins , Marion Ott , John Mascarenhas , Michael Andreeff

MYC protein expression is an important prognostic factor in acute myeloid leukemia.

Leukemia & lymphoma
Avec: Maro Ohanian , Uri Rozovski , Rashmi Kanagal-Shamanna , Lynne V Abruzzo , Sanam Loghavi , Tapan Kadia , Andrew Futreal , Kapil Bhalla , Zhuang Zuo , Yang O Huh , Sean M Post , Peter Ruvolo , Guillermo Garcia-Manero , Michael Andreeff , Steven Kornblau , Gautam Borthakur , Peter Hu , L Jeffrey Medeiros , Koichi Takahashi , Marisa J Hornbaker , Jianhua Zhang , Graciela M Nogueras-González , Xuelin Huang , Srdan Verstovsek , Zeev Estrov , Sherry Pierce , Farhad Ravandi , Hagop M Kantarjian , Carlos E Bueso-Ramos , Jorge E Cortes

Efficacy, Safety, and Biomarkers of Response to Azacitidine and Nivolumab in Relapsed/Refractory Acute Myeloid Leukemia: A Nonrandomized, Open-Label, Phase II Study.

Cancer discovery
Avec: Naval Daver , Guillermo Garcia-Manero , Sreyashi Basu , Prajwal C Boddu , Mansour Alfayez , Jorge E Cortes , Marina Konopleva , Farhad Ravandi-Kashani , Elias Jabbour , Tapan Kadia , Graciela M Nogueras-Gonzalez , Jing Ning , Naveen Pemmaraju , Courtney D DiNardo , Michael Andreeff , Sherry A Pierce , Tauna Gordon , Steven M Kornblau , Wilmer Flores , Zainab Alhamal , Carlos Bueso-Ramos , Jeffrey L Jorgensen , Keyur P Patel , Jorge Blando , James P Allison , Padmanee Sharma , Hagop Kantarjian

A phase II study of omacetaxine mepesuccinate for patients with higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia after failure of hypomethylating agents.

American journal of hematology
Avec: Nicholas J Short , Elias Jabbour , Kiran Naqvi , Ami Patel , Jing Ning , Koji Sasaki , Graciela M Nogueras-Gonzalez , Prithviraj Bose , Steven M Kornblau , Koichi Takahashi , Michael Andreeff , Gabriela Sanchez-Petitto , Zeev Estrov , Courtney D Dinardo , Guillermo Montalban-Bravo , Marina Konopleva , Yesid Alvarado , Kapil N Bhalla , Warren Fiskus , Maria Khouri , Rubiul Islam , Hagop Kantarjian , Guillermo Garcia-Manero

Réseau de co-auteurs

Marina Konopleva 36 collaborations
Gautam Borthakur 32 collaborations
Guillermo Garcia-Manero 32 collaborations
Farhad Ravandi 31 collaborations
Courtney D DiNardo 26 collaborations
Naval Daver 25 collaborations
Elias Jabbour 24 collaborations
Naveen Pemmaraju 23 collaborations
Hagop M Kantarjian 22 collaborations
Nicholas J Short 21 collaborations
Koichi Takahashi 18 collaborations
Tapan M Kadia 16 collaborations
Koji Sasaki 16 collaborations
Hagop Kantarjian 16 collaborations
Musa Yilmaz 14 collaborations
Bing Z Carter 14 collaborations
Nitin Jain 14 collaborations
Tapan Kadia 14 collaborations
Ghayas C Issa 14 collaborations
Sanam Loghavi 13 collaborations
Maro Ohanian 13 collaborations
Marina Y Konopleva 13 collaborations
Yesid Alvarado 11 collaborations
Jing Ning 11 collaborations
Jorge E Cortes 11 collaborations
Sherry Pierce 11 collaborations
Naval G Daver 11 collaborations
Keyur P Patel 10 collaborations
Vivian Ruvolo 10 collaborations
Guillermo Montalban-Bravo 10 collaborations
Jo Ishizawa 9 collaborations
Abhishek Maiti 9 collaborations
Elias J Jabbour 9 collaborations
Alessandra Ferrajoli 8 collaborations
Rashmi Kanagal-Shamanna 8 collaborations
Prithviraj Bose 8 collaborations
Muharrem Muftuoglu 8 collaborations
Kiran Naqvi 7 collaborations
Wei Qiao 7 collaborations
Po Yee Mak 7 collaborations
Zeev Estrov 7 collaborations
Sa A Wang 7 collaborations
Lucia Masarova 7 collaborations
Mahesh Basyal 7 collaborations
Steven M Kornblau 7 collaborations
Srdan Verstovsek 7 collaborations
Steven Kornblau 7 collaborations
Wenjing Tao 6 collaborations
Natalia Baran 6 collaborations
Xuelin Huang 6 collaborations
Jorge Cortes 6 collaborations
Sherry A Pierce 6 collaborations
Courtney DiNardo 6 collaborations
Qi Zhang 6 collaborations
Vivian R Ruvolo 6 collaborations
Yuki Nishida 6 collaborations
Weiguo Zhang 6 collaborations
William G Wierda 5 collaborations
Ghayas Issa 5 collaborations
Lianchun Xiao 5 collaborations
Hong Mu 4 collaborations
Jan A Burger 4 collaborations
Graciela M Nogueras-Gonzalez 4 collaborations
Lina Han 4 collaborations
Yoko Tabe 4 collaborations
Charlie Ly 4 collaborations
Kapil N Bhalla 4 collaborations
Keyur Patel 4 collaborations
Helen Ma 4 collaborations
Kapil Bhalla 4 collaborations
Rafael Heinz Montoya 4 collaborations
Lauren B Ostermann 4 collaborations
Ran Zhao 4 collaborations
Bin Yuan 4 collaborations
Carlos Bueso-Ramos 4 collaborations
Jared K Burks 4 collaborations
Rasoul Pourebrahim 4 collaborations
Jörg Kotzerke 4 collaborations
Curtis A Lachowiez 3 collaborations
Nicholas Short 3 collaborations
Xiangmeng Wang 3 collaborations
Duncan H Mak 3 collaborations
Takahiko Seki 3 collaborations
Sujan Piya 3 collaborations
Philip L Lorenzi 3 collaborations
R Eric Davis 3 collaborations
Takashi Miida 3 collaborations
Yulia Jitkova 3 collaborations
Mark D Minden 3 collaborations
Joseph R Marszalek 3 collaborations
Carlos E Bueso-Ramos 3 collaborations
Courtney D Dinardo 3 collaborations
Edward Ayoub 3 collaborations
Kensuke Kojima 3 collaborations
Branko Cuglievan 3 collaborations
Martin Stogniew 3 collaborations
Venkata Lokesh Battula 3 collaborations
Caitlin R Rausch 3 collaborations
Philip A Thompson 3 collaborations
Sean M Post 3 collaborations
Peter P Ruvolo 3 collaborations
Pierre Fenaux 3 collaborations
Yuanqing Yan 3 collaborations
Li Li 3 collaborations
Duncan Mak 3 collaborations
Ken Chen 3 collaborations
Antonio Cavazos 3 collaborations
Lauren Ostermann 3 collaborations
Hiroki Akiyama 3 collaborations
Guopan Yu 3 collaborations
Hongying Zhang 3 collaborations
William G Rice 3 collaborations
Hussein A Abbas 3 collaborations
Monique Dail 3 collaborations
Giovanni Martinelli 3 collaborations
Sherry R Pierce 2 collaborations
Simón Méndez-Ferrer 2 collaborations
Dominique Bonnet 2 collaborations
Daniela S Krause 2 collaborations
Seemana Bhattacharya 2 collaborations
Teresa McQueen 2 collaborations
Jeffrey Jorgensen 2 collaborations
Michael J Keating 2 collaborations
Zhihong Zeng 2 collaborations
Ahmad S Alotaibi 2 collaborations
Guilin Tang 2 collaborations
Veronica Guerra 2 collaborations
Guillin Tang 2 collaborations
Venkata L Battula 2 collaborations
Rose Hurren 2 collaborations
Marcela Gronda 2 collaborations
Neil MacLean 2 collaborations
Zoe Alaniz 2 collaborations
Aaron D Schimmer 2 collaborations
Kaori Saito 2 collaborations
Kotoko Yamatani 2 collaborations
Tomohiko Ai 2 collaborations
Tianyu Cai 2 collaborations
Rodrigo Jacamo 2 collaborations
Sonoko Kinjo 2 collaborations
Kazuho Ikeo 2 collaborations
Koya Suzuki 2 collaborations
Yannan Jia 2 collaborations
Alessia Lodi 2 collaborations
Saravanan Ganesan 2 collaborations
Wencai Ma 2 collaborations
Connie C Weng 2 collaborations
Cassandra L Ramage 2 collaborations
Ce Shi 2 collaborations
Jing Wang 2 collaborations
Rose Ann Padua 2 collaborations
Stefano Tiziani 2 collaborations
Walid Macaron 2 collaborations
Shayaun Khazaei 2 collaborations
Steffen Boettcher 2 collaborations
Benjamin L Ebert 2 collaborations
Farhad Ravandi-Kashani 2 collaborations
Takenobu Nii 2 collaborations
Sergej Konoplev 2 collaborations
Joseph D Khoury 2 collaborations
Joshua E Allen 2 collaborations
Varun V Prabhu 2 collaborations
Neel Madhukar 2 collaborations
Olivier Elemento 2 collaborations
Wolfgang Oster 2 collaborations
Stanley Ly 2 collaborations
Elizabeth J Shpall 2 collaborations
Mansour Alfayez 2 collaborations
Rita Assi 2 collaborations
Shaoheng Liang 2 collaborations
Lynette Alexander 2 collaborations
Mecit Kaplan 2 collaborations
Ken Furudate 2 collaborations
Karine Harutyunyan 2 collaborations
Gheath Al-Atrash 2 collaborations
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