Stephanie Halene

Affiliations

Section of Hematology, Department of Internal Medicine, Yale University School of Medicine and Yale Comprehensive Cancer Center, New Haven, CT, USA; Yale Stem Cell Center and Yale RNA Center, Yale University School of Medicine, New Haven, CT, USA.

Publications (58)

The minimal that kills: Why defining and targeting measurable residual disease is the "Sine Qua Non" for further progress in management of acute myeloid leukemia.

Blood reviews

Avec: Jan Philipp Bewersdorf , Rory M Shallis , Prajwal C Boddu , Brent Wood , Jerald Radich , Stephanie Halene , Amer M Zeidan

Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity.

Journal of medicinal chemistry

Avec: Xiaoyang Li , Yuqi Jiang , Yuri K Peterson , Tongqiang Xu , Richard A Himes , Xin Luo , Guilin Yin , Elizabeth S Inks , Nathan Dolloff , Stephanie Halene , Sherine S L Chan , C James Chou

Comprehensive Clinicopathologic and Molecular Analysis of Mast Cell Leukemia With Associated Hematologic Neoplasm: A Report and In-Depth Study of 5 Cases.

Frontiers in oncology

Avec: Philippa Li , Giulia Biancon , Timil Patel , Zenggang Pan , Shalin Kothari , Stephanie Halene , Thomas Prebet , Mina L Xu

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue.

Cell

Avec: Yang Liu , Mingyu Yang , Yanxiang Deng , Graham Su , Archibald Enninful , Cindy C Guo , Toma Tebaldi , Di Zhang , Dongjoo Kim , Zhiliang Bai , Eileen Norris , Alisia Pan , Jiatong Li , Yang Xiao , Stephanie Halene , Rong Fan

Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation.

Nature reviews. Cardiology

Avec: Sean X Gu , Tarun Tyagi , Kanika Jain , Vivian W Gu , Seung Hee Lee , Jonathan M Hwa , Jennifer M Kwan , Diane S Krause , Alfred I Lee , Stephanie Halene , Kathleen A Martin , Hyung J Chun , John Hwa

A neutrophil activation signature predicts critical illness and mortality in COVID-19.

Blood advances

Avec: Matthew L Meizlish , Alexander B Pine , Jason D Bishai , George Goshua , Emily R Nadelmann , Michael Simonov , C-Hong Chang , Hanming Zhang , Marcus Shallow , Parveen Bahel , Kent Owusu , Yu Yamamoto , Tanima Arora , Deepak S Atri , Amisha Patel , Rana Gbyli , Jennifer Kwan , Christine H Won , Charles Dela Cruz , Christina Price , Jonathan Koff , Brett A King , Henry M Rinder , F Perry Wilson , John Hwa , Stephanie Halene , William Damsky , David van Dijk , Alfred I Lee , Hyung J Chun

Inflammasome activation in infected macrophages drives COVID-19 pathology.

Nature

Avec: Esen Sefik , Rihao Qu , Caroline Junqueira , Eleanna Kaffe , Haris Mirza , Jun Zhao , J Richard Brewer , Ailin Han , Holly R Steach , Benjamin Israelow , Holly N Blackburn , Sofia E Velazquez , Y Grace Chen , Stephanie Halene , Akiko Iwasaki , Eric Meffre , Michel Nussenzweig , Judy Lieberman , Craig B Wilen , Yuval Kluger , Richard A Flavell

Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies.

Open forum infectious diseases

Avec: Jane C Figueiredo , Fred R Hirsch , Lawrence H Kushi , Wendy N Nembhard , James M Crawford , Nicholas Mantis , Laurel Finster , Noah M Merin , Akil Merchant , Karen L Reckamp , Gil Y Melmed , Jonathan Braun , Dermot McGovern , Samir Parekh , Douglas A Corley , Namvar Zohoori , Benjamin C Amick , Ruofei Du , Peter K Gregersen , Betty Diamond , Emanuela Taioli , Carlos Sariol , Ana Espino , Daniela Weiskopf , Alba Gifoni , James Brien , William Hanege , Marc Lipsitch , David A Zidar , Ann Scheck McAlearney , Ania Wajnberg , Joshua LaBaer , E Yvonne Lewis , Raquel A Binder , Ann M Moormann , Catherine Forconi , Sarah Forrester , Jennifer Batista , John Schieffelin , Dongjoo Kim , Giulia Biancon , Jennifer VanOudenhove , Stephanie Halene , Rong Fan , Dan H Barouch , Galit Alter , Swetha Pinninti , Suresh B Boppana , Sunil K Pati , Misty Latting , Andrew H Karaba , John Roback , Rafick Sekaly , Andrew Neish , Ahnalee M Brincks , Douglas A Granger , Amy B Karger , Bharat Thyagarajan , Stefani N Thomas , Sabra L Klein , Andrea L Cox , Todd Lucas , Debra Furr-Holden , Kent Key , Nicole Jones , Jens Wrammerr , Mehul Suthar , Serre Yu Wong , Natalie M Bowman , Viviana Simon , Lynne D Richardson , Russell McBride , Florian Krammer , Meenakshi Rana , Joshua Kennedy , Karl Boehme , Craig Forrest , Steve W Granger , Christopher D Heaney , Maria Knight Lapinski , Shannon Wallet , Ralph S Baric , Luca Schifanella , Marcos Lopez , Soledad Fernández , Eben Kenah , Ashish R Panchal , William J Britt , Iñaki Sanz , Madhav Dhodapkar , Rafi Ahmed , Luther A Bartelt , Alena J Markmann , Jessica T Lin , Robert S Hagan , Matthew C Wolfgang , Jacek Skarbinski

A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options.

Research square

Avec: Esen Sefik , Ben Israelow , Jun Zhao , Rihao Qu , Eric Song , Haris Mirza , Eleanna Kaffe , Stephanie Halene , Eric Meffre , Yuval Kluger , Michel Nussenzweig , Craig B Wilen , Akiko Iwasaki , Richard A Flavell

Transcriptome-wide quantification of double-stranded RNAs in live mouse tissues by dsRIP-Seq.

STAR protocols

Avec: Yimeng Gao , Shirui Chen , Stephanie Halene , Toma Tebaldi

Inflammasome activation in infected macrophages drives COVID-19 pathology.

bioRxiv : the preprint server for biology

Avec: Esen Sefik , Rihao Qu , Caroline Junqueira , Eleanna Kaffe , Haris Mirza , Jun Zhao , J Richard Brewer , Ailin Han , Holly R Steach , Benjamin Israelow , Holly N Blackburn , Sofia Velazquez , Y Grace Chen , Stephanie Halene , Akiko Iwasaki , Eric Meffre , Michel Nussenzweig , Judy Lieberman , Craig B Wilen , Yuval Kluger , Richard A Flavell

Integrated genetic, epigenetic, and immune landscape of

Therapeutic advances in hematology

Avec: Amer M Zeidan , Jan Philipp Bewersdorf , Vanessa Hasle , Rory M Shallis , Ethan Thompson , Daniel Lopes de Menezes , Shelonidta Rose , Isaac Boss , Stephanie Halene , Torsten Haferlach , Brian A Fox

High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq.

Nature biotechnology

Avec: Yang Liu , Marcello DiStasio , Graham Su , Hiromitsu Asashima , Archibald Enninful , Xiaoyu Qin , Yanxiang Deng , Jungmin Nam , Fu Gao , Pino Bordignon , Marco Cassano , Mary Tomayko , Mina Xu , Stephanie Halene , Joseph E Craft , David Hafler , Rong Fan

Microfluidic Immuno-Serolomic Assay Reveals Systems Level Association with COVID-19 Pathology and Vaccine Protection.

Small methods

Avec: Dongjoo Kim , Giulia Biancon , Zhiliang Bai , Jennifer VanOudenhove , Yuxin Liu , Shalin Kothari , Lohith Gowda , Jennifer M Kwan , Nicholas Carlos Buitrago-Pocasangre , Nikhil Lele , Hiromitsu Asashima , Michael K Racke , JoDell E Wilson , Tara S Givens , Mary M Tomayko , Wade L Schulz , Erin E Longbrake , David A Hafler , Stephanie Halene , Rong Fan

Interpreting single-cell messages in normal and aberrant hematopoiesis with the Cell Marker Accordion.

bioRxiv : the preprint server for biology

Avec: Emma Busarello , Giulia Biancon , Fabio Lauria , Zuhairia Ibnat , Christian Ramirez , Gabriele Tomè , Kristin R Aass , Jennifer VanOudenhove , Therese Standal , Gabriella Viero , Stephanie Halene , Toma Tebaldi

Contemporary Approach to The Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes- Recommendations from The International Consortium for MDS (icMDS).

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Avec: Fnu Aakash , Savanah D Gisriel , Amer M Zeidan , John M Bennett , Rafael Bejar , Jan Philipp Bewersdorf , Uma M Borate , Jacqueline Boultwood , Andrew M Brunner , Rena Buckstein , Hetty Carraway , Jane E Churpek , Naval G Daver , Amy E DeZern , Fabio Efficace , Pierre Fenaux , Maria E Figueroa , Guillero Garcia-Manero , Steven D Gore , Peter L Greenberg , Elizabeth A Griffiths , Stephanie Halene , Christopher S Hourigan , Tae Kon Kim , Nina Kim , Rami S Komrokji , Vijay Kutchroo , Alan F List , Richard F Little , Ravindra Majeti , Aziz Nazha , Stephen D Nimer , Olatoyosi Odenike , Eric Padron , Mrinal M Patnaik , Uwe Platzbecker , Matteo G Della Porta , Gail J Roboz , David A Sallman , Valeria Santini , Guillermo Sanz , Michael R Savona , Mikkael A Sekeres , Maximilian Stahl , Daniel T Starczynowski , David P Steensma , Justin Taylor , Omer Abdel-Wahab , Andrew H Wei , Xie Zhuoer , Mina L Xu , Robert P Hasserjian , Sanam Loghavi

A neutrophil activation signature predicts critical illness and mortality in COVID-19.

medRxiv : the preprint server for health sciences

Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms.

Blood

Avec: Justin Taylor , Xiaoli Mi , Khrystyna North , Moritz Binder , Alexander Penson , Terra Lasho , Katherine Knorr , Michael Haddadin , Bo Liu , Joseph Pangallo , Salima Benbarche , Daniel Wiseman , Ayalew Tefferi , Stephanie Halene , Yang Liang , Mrinal M Patnaik , Robert K Bradley , Omar Abdel-Wahab

Functional Analysis of Human Hematopoietic Stem Cells In Vivo in Humanized Mice.

Methods in molecular biology (Clifton, N.J.)

Avec: Yuanbin Song , Rana Gbyli , Xiaoying Fu , Stephanie Halene

LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML.

Blood advances

Avec: Neil Beeharry , Sean Landrette , Sophia Gayle , Marylens Hernandez , Jeff E Grotzke , Peter R Young , Paul Beckett , Xuan Zhang , Bing Z Carter , Michael Andreeff , Stephanie Halene , Tian Xu , Jonathan Rothberg , Henri Lichenstein

Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells.

Science (New York, N.Y.)

Avec: Yuanbin Song , Liang Shan , Rana Gbyli , Wei Liu , Till Strowig , Amisha Patel , Xiaoying Fu , Xiaman Wang , Mina L Xu , Yimeng Gao , Ashley Qin , Emanuela M Bruscia , Toma Tebaldi , Giulia Biancon , Padmavathi Mamillapalli , David Urbonas , Elizabeth Eynon , David G Gonzalez , Jie Chen , Diane S Krause , Jonathan Alderman , Stephanie Halene , Richard A Flavell

The role of RNA epigenetic modification in normal and malignant hematopoiesis.

Current stem cell reports

Avec: Radovan Vasic , Yimeng Gao , Chengyang Liu , Stephanie Halene

In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2.

Leukemia

Avec: Rana Gbyli , Yuanbin Song , Wei Liu , Yimeng Gao , Giulia Biancon , Namrata S Chandhok , Xiaman Wang , Xiaoying Fu , Amisha Patel , Ranjini Sundaram , Toma Tebaldi , Padmavathi Mamillapalli , Amer M Zeidan , Richard A Flavell , Thomas Prebet , Ranjit S Bindra , Stephanie Halene

The Coming of Age of Preclinical Models of MDS.

Frontiers in oncology

Avec: Wei Liu , Patric Teodorescu , Stephanie Halene , Gabriel Ghiaur

Spatial profiling of chromatin accessibility in mouse and human tissues.

Nature

Avec: Yanxiang Deng , Marek Bartosovic , Sai Ma , Di Zhang , Petra Kukanja , Yang Xiao , Graham Su , Yang Liu , Xiaoyu Qin , Gorazd B Rosoklija , Andrew J Dwork , J John Mann , Mina L Xu , Stephanie Halene , Joseph E Craft , Kam W Leong , Maura Boldrini , Gonçalo Castelo-Branco , Rong Fan

Microfluidic immuno-serology assay revealed a limited diversity of protection against COVID-19 in patients with altered immunity.

bioRxiv : the preprint server for biology

Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS).

Blood reviews

Avec: Maximilian Stahl , Jan Philipp Bewersdorf , Zhuoer Xie , Matteo Giovanni Della Porta , Rami Komrokji , Mina L Xu , Omar Abdel-Wahab , Justin Taylor , David P Steensma , Daniel T Starczynowski , Mikkael A Sekeres , Guillermo Sanz , David A Sallman , Gail J Roboz , Uwe Platzbecker , Mrinal M Patnaik , Eric Padron , Olatoyosi Odenike , Stephen D Nimer , Aziz Nazha , Ravi Majeti , Sanam Loghavi , Richard F Little , Alan F List , Tae Kon Kim , Christopher S Hourigan , Robert P Hasserjian , Stephanie Halene , Elizabeth A Griffiths , Steven D Gore , Peter Greenberg , Maria E Figueroa , Pierre Fenaux , Fabio Efficace , Amy E DeZern , Naval G Daver , Jane E Churpek , Hetty E Carraway , Rena Buckstein , Andrew M Brunner , Jacqueline Boultwood , Uma Borate , Rafael Bejar , John M Bennett , Andrew H Wei , Valeria Santini , Michael R Savona , Amer M Zeidan

PD-1H/VISTA mediates immune evasion in acute myeloid leukemia.

The Journal of clinical investigation

Avec: Tae Kon Kim , Xue Han , Qianni Hu , Esten N Vandsemb , Carly M Fielder , Junshik Hong , Kwang Woon Kim , Emily F Mason , R Skipper Plowman , Jun Wang , Qi Wang , Jian-Ping Zhang , Ti Badri , Miguel F Sanmamed , Linghua Zheng , Tianxiang Zhang , Jude Alawa , Sang Won Lee , Amer M Zeidan , Stephanie Halene , Manoj M Pillai , Namrata S Chandhok , Jun Lu , Mina L Xu , Steven D Gore , Lieping Chen

Splicing the Difference: Harnessing the complexity of the transcriptome in hematopoiesis.

Experimental hematology

Avec: Hannah M Maul-Newby , Stephanie Halene

Humanized mice as preclinical models for myeloid malignancies.

Biochemical pharmacology

Avec: Rana Gbyli , Yuanbin Song , Stephanie Halene

Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.

Blood

Avec: Juliana Xavier-Ferrucio , Vanessa Scanlon , Xiuqi Li , Ping-Xia Zhang , Larisa Lozovatsky , Nadia Ayala-Lopez , Toma Tebaldi , Stephanie Halene , Chang Cao , Mark D Fleming , Karin E Finberg , Diane S Krause

From clonal hematopoiesis to myeloid leukemia and what happens in between: Will improved understanding lead to new therapeutic and preventive opportunities?

Blood reviews

Avec: Jan Philipp Bewersdorf , Anastasia Ardasheva , Nikolai A Podoltsev , Abhay Singh , Giulia Biancon , Stephanie Halene , Amer M Zeidan

Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study.

The Lancet. Haematology

Avec: George Goshua , Alexander B Pine , Matthew L Meizlish , C-Hong Chang , Hanming Zhang , Parveen Bahel , Audrey Baluha , Noffar Bar , Robert D Bona , Adrienne J Burns , Charles S Dela Cruz , Anne Dumont , Stephanie Halene , John Hwa , Jonathan Koff , Hope Menninger , Natalia Neparidze , Christina Price , Jonathan M Siner , Christopher Tormey , Henry M Rinder , Hyung J Chun , Alfred I Lee

Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.

Nucleic acids research

Avec: Eliezra Glasser , Debanjana Maji , Giulia Biancon , Anees Mohammed Keedakkatt Puthenpeedikakkal , Chapin E Cavender , Toma Tebaldi , Jermaine L Jenkins , David H Mathews , Stephanie Halene , Clara L Kielkopf

ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m

Cell reports

Avec: Yimeng Gao , Joshua T Zimmer , Radovan Vasic , Chengyang Liu , Rana Gbyli , Shu-Jian Zheng , Amisha Patel , Wei Liu , Zhihong Qi , Yaping Li , Raman Nelakanti , Yuanbin Song , Giulia Biancon , Andrew Z Xiao , Sarah Slavoff , Richard G Kibbey , Richard A Flavell , Matthew D Simon , Toma Tebaldi , Hua-Bing Li , Stephanie Halene

Impact of Memory T Cells on SARS-COV-2 Vaccine Response in Hematopoietic Stem Cell Transplant.

bioRxiv : the preprint server for biology

Avec: Jennifer VanOudenhove , Yuxin Liu , Raman Nelakanti , Dongjoo Kim , Emma Busarello , Natalia Tijaro Ovalle , Zhihong Qi , Padmavathi Mamillapalli , Alexa Siddon , Zhiliang Bai , Alfredo Axtmayer , Cheryl Corso , Shalin Kothari , Francine Foss , Iris Isufi , Toma Tebaldi , Lohith Gowda , Rong Fan , Stuart Seropian , Stephanie Halene

Selective inhibition of MCL1 overcomes venetoclax resistance in a murine model of myelodysplastic syndromes.

Haematologica

Avec: Melissa A Fischer , Yuanbin Song , Maria P Arrate , Rana Gbyli , Matthew T Villaume , Brianna N Smith , Merrida A Childress , Thomas P Stricker , Stephanie Halene , Michael R Savona

Widespread association of the Argonaute protein AGO2 with meiotic chromatin suggests a distinct nuclear function in mammalian male reproduction.

Genome research

Avec: Kimberly N Griffin , Benjamin William Walters , Haixin Li , Huafeng Wang , Giulia Biancon , Toma Tebaldi , Carolyn B Kaya , Jean Kanyo , TuKiet T Lam , Andy L Cox , Stephanie Halene , Jean-Ju Chung , Bluma J Lesch

Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1

Blood reviews

Avec: Jan Philipp Bewersdorf , Zhuoer Xie , Rafael Bejar , Uma Borate , Jacqueline Boultwood , Andrew M Brunner , Rena Buckstein , Hetty E Carraway , Jane E Churpek , Naval G Daver , Matteo Giovanni Della Porta , Amy E DeZern , Pierre Fenaux , Maria E Figueroa , Steven D Gore , Elizabeth A Griffiths , Stephanie Halene , Robert P Hasserjian , Christopher S Hourigan , Tae Kon Kim , Rami Komrokji , Vijay K Kuchroo , Alan F List , Sanam Loghavi , Ravindra Majeti , Olatoyosi Odenike , Mrinal M Patnaik , Uwe Platzbecker , Gail J Roboz , David A Sallman , Valeria Santini , Guillermo Sanz , Mikkael A Sekeres , Maximilian Stahl , Daniel T Starczynowski , David P Steensma , Justin Taylor , Omar Abdel-Wahab , Mina L Xu , Michael R Savona , Andrew H Wei , Amer M Zeidan

The human CD47 checkpoint is targeted by an immunosuppressive

Science immunology

Avec: Alejandro Marin-Lopez , John D Huck , Allen T Esterly , Veronica Azcutia , Connor Rosen , Rolando Garcia-Milian , Esen Sefik , Gemma Vidal-Pedrola , Hamidah Raduwan , Tse-Yu Chen , Gunjan Arora , Stephanie Halene , Albert C Shaw , Noah W Palm , Richard A Flavell , Charles A Parkos , Saravanan Thangamani , Aaron M Ring , Erol Fikrig

Aplastic anemia in association with multiple myeloma: clinical and pathophysiological insights.

Leukemia & lymphoma

Avec: Tinatin Muradashvili , Yuxin Liu , Jennifer VanOudenhove , Sean X Gu , Diane S Krause , Francesca Montanari , Maximillian J Carlino , Rubia Mancuso , Jessica M Stempel , Stephanie Halene , Amer M Zeidan , Nikolai A Podoltsev , Natalia Neparidze

m

Immunity

Avec: Yimeng Gao , Radovan Vasic , Yuanbin Song , Rhea Teng , Chengyang Liu , Rana Gbyli , Giulia Biancon , Raman Nelakanti , Kirsten Lobben , Eriko Kudo , Wei Liu , Anastasia Ardasheva , Xiaoying Fu , Xiaman Wang , Poorval Joshi , Veronica Lee , Burak Dura , Gabriella Viero , Akiko Iwasaki , Rong Fan , Andrew Xiao , Richard A Flavell , Hua-Bing Li , Toma Tebaldi , Stephanie Halene

Cyclosporine enhances the sensitivity to lenalidomide in MDS/AML in vitro.

Experimental hematology

Avec: Xiaofei He , Aixia Dou , Saran Feng , Ashley Roman-Rivera , Caleb Hawkins , Lauren Lawley , Jiajia Zhang , Mark Wunderlich , Benjamin Mizukawa , Stephanie Halene , Amisha Patel , Jing Fang

A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies.

Nature communications

Avec: Yuanbin Song , Anthony Rongvaux , Ashley Taylor , Tingting Jiang , Toma Tebaldi , Kunthavai Balasubramanian , Arun Bagale , Yunus Kasim Terzi , Rana Gbyli , Xiaman Wang , Xiaoying Fu , Yimeng Gao , Jun Zhao , Nikolai Podoltsev , Mina Xu , Natalia Neparidze , Ellice Wong , Richard Torres , Emanuela M Bruscia , Yuval Kluger , Markus G Manz , Richard A Flavell , Stephanie Halene

A humanized mouse model of chronic COVID-19.

Nature biotechnology

Avec: Esen Sefik , Benjamin Israelow , Haris Mirza , Jun Zhao , Rihao Qu , Eleanna Kaffe , Eric Song , Stephanie Halene , Eric Meffre , Yuval Kluger , Michel Nussenzweig , Craig B Wilen , Akiko Iwasaki , Richard A Flavell

Circulating markers of angiogenesis and endotheliopathy in COVID-19.

Pulmonary circulation

Avec: Alexander B Pine , Matthew L Meizlish , George Goshua , C-Hong Chang , Hanming Zhang , Jason Bishai , Parveen Bahel , Amisha Patel , Rana Gbyli , Jennifer M Kwan , Christine H Won , Christina Price , Charles S Dela Cruz , Stephanie Halene , David van Dijk , John Hwa , Alfred I Lee , Hyung J Chun

Circulating Markers of Angiogenesis and Endotheliopathy in COVID-19.

medRxiv : the preprint server for health sciences

Avec: Matthew L Meizlish , Alexander B Pine , George Goshua , C-Hong Chang , Hanming Zhang , Jason Bishai , Parveen Bahel , Amisha Patel , Rana Gbyli , Jennifer Kwan , Christina Price , Charles S Dela Cruz , Stephanie Halene , David van Dijk , John Hwa , Alfred I Lee , Hyung J Chun

Spatial-CITE-seq: spatially resolved high-plex protein and whole transcriptome co-mapping.

Research square

Avec: Yang Liu , Marcello DiStasio , Graham Su , Hiromitsu Asashima , Archibald Enninful , Xiaoyu Qin , Yanxiang Deng , Pino Bordignon , Marco Cassano , Mary Tomayko , Mina Xu , Stephanie Halene , Joseph E Craft , David Hafler , Rong Fan

Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.

Molecular cell

Avec: Giulia Biancon , Poorval Joshi , Joshua T Zimmer , Torben Hunck , Yimeng Gao , Mark D Lessard , Edward Courchaine , Andrew E S Barentine , Martin Machyna , Valentina Botti , Ashley Qin , Rana Gbyli , Amisha Patel , Yuanbin Song , Lea Kiefer , Gabriella Viero , Nils Neuenkirchen , Haifan Lin , Joerg Bewersdorf , Matthew D Simon , Karla M Neugebauer , Toma Tebaldi , Stephanie Halene

A Phase 2 Randomized, Double-Blind, Placebo-controlled Trial of Oral Camostat Mesylate for Early Treatment of COVID-19 Outpatients Showed Shorter Illness Course and Attenuation of Loss of Smell and Taste.

medRxiv : the preprint server for health sciences

Avec: Geoffrey Chupp , Anne Spichler-Moffarah , Ole S Søgaard , Denise Esserman , James Dziura , Lisa Danzig , Reetika Chaurasia , Kailash P Patra , Aryeh Salovey , Angela Nunez , Jeanine May , Lauren Astorino , Amisha Patel , Stephanie Halene , Jianhui Wang , Pei Hui , Prashant Patel , Jing Lu , Fangyong Li , Geliang Gan , Stephen Parziale , Lily Katsovich , Gary V Desir , Joseph M Vinetz

Are We Moving the Needle for Patients with

Cancers

Avec: Rory M Shallis , Jan P Bewersdorf , Maximilian F Stahl , Stephanie Halene , Amer M Zeidan

Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts.

Blood cancer discovery

Avec: Vera Adema , Feiyang Ma , Rashmi Kanagal-Shamanna , Natthakan Thongon , Guillermo Montalban-Bravo , Hui Yang , Scott A Peslak , Feng Wang , Pamela Acha , Francesc Sole , Pamela Lockyer , Margherita Cassari , Jaroslaw P Maciejewski , Valeria Visconte , Irene Gañán-Gómez , Yuanbin Song , Carlos Bueso-Ramos , Matteo Pellegrini , Tuyet M Tan , Rafael Bejar , Jennifer S Carew , Stephanie Halene , Valeria Santini , Gheath Al-Atrash , Karen Clise-Dwyer , Guillermo Garcia-Manero , Gerd A Blobel , Simona Colla

Human neutrophil development and functionality are enabled in a humanized mouse model.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Yunjiang Zheng , Esen Sefik , John Astle , Kutay Karatepe , Hasan H Öz , Angel G Solis , Ruaidhrí Jackson , Hongbo R Luo , Emanuela M Bruscia , Stephanie Halene , Liang Shan , Richard A Flavell

A multicenter phase Ib trial of the histone deacetylase inhibitor entinostat in combination with pembrolizumab in patients with myelodysplastic syndromes/neoplasms or acute myeloid leukemia refractory to hypomethylating agents.

Annals of hematology

Avec: Jan Philipp Bewersdorf , Rory M Shallis , Elad Sharon , Silvia Park , Rahul Ramaswamy , Caroline E Roe , Jonathan M Irish , Anne Caldwell , Wei Wei , Abdulraheem Yacoub , Yazan F Madanat , Joshua F Zeidner , Jessica K Altman , Olatoyosi Odenike , Swaroopa Yerrabothala , Tibor Kovacsovics , Nikolai A Podoltsev , Stephanie Halene , Richard F Little , Richard Piekarz , Steven D Gore , Tae Kon Kim , Amer M Zeidan

Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis.

Cell reports

Avec: Hasan H Öz , Ee-Chun Cheng , Caterina Di Pietro , Toma Tebaldi , Giulia Biancon , Caroline Zeiss , Ping-Xia Zhang , Pamela H Huang , Sofia S Esquibies , Clemente J Britto , Jonas C Schupp , Thomas S Murray , Stephanie Halene , Diane S Krause , Marie E Egan , Emanuela M Bruscia

Is it the time to integrate novel sequencing technologies into clinical practice?

Current opinion in hematology

Avec: Jennifer VanOudenhove , Stephanie Halene , Lourdes Mendez

Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq.

STAR protocols

Avec: Giulia Biancon , Emma Busarello , Poorval Joshi , Bluma J Lesch , Stephanie Halene , Toma Tebaldi

Data-driven, harmonised classification system for myelodysplastic syndromes: a consensus paper from the International Consortium for Myelodysplastic Syndromes.

The Lancet. Haematology

Avec: Rami S Komrokji , Luca Lanino , Somedeb Ball , Jan P Bewersdorf , Monia Marchetti , Giulia Maggioni , Erica Travaglino , Najla H Al Ali , Pierre Fenaux , Uwe Platzbecker , Valeria Santini , Maria Diez-Campelo , Avani Singh , Akriti G Jain , Luis E Aguirre , Sarah M Tinsley-Vance , Zaker I Schwabkey , Onyee Chan , Zhouer Xie , Andrew M Brunner , Andrew T Kuykendall , John M Bennett , Rena Buckstein , Rafael Bejar , Hetty E Carraway , Amy E DeZern , Elizabeth A Griffiths , Stephanie Halene , Robert P Hasserjian , Jeffrey Lancet , Alan F List , Sanam Loghavi , Olatoyosi Odenike , Eric Padron , Mrinal M Patnaik , Gail J Roboz , Maximilian Stahl , Mikkael A Sekeres , David P Steensma , Michael R Savona , Justin Taylor , Mina L Xu , Kendra Sweet , David A Sallman , Stephen D Nimer , Christopher S Hourigan , Andrew H Wei , Elisabetta Sauta , Saverio D'Amico , Gianluca Asti , Gastone Castellani , Mattia Delleani , Alessia Campagna , Uma M Borate , Guillermo Sanz , Fabio Efficace , Steven D Gore , Tae Kon Kim , Navel Daver , Guillermo Garcia-Manero , Maria Rozman , Alberto Orfao , Sa A Wang , M Kathryn Foucar , Ulrich Germing , Torsten Haferlach , Phillip Scheinberg , Yasushi Miyazaki , Marcelo Iastrebner , Austin Kulasekararaj , Thomas Cluzeau , Shahram Kordasti , Arjan A van de Loosdrecht , Lionel Ades , Amer M Zeidan , Matteo G Della Porta , Auteur inconnu

Réseau de co-auteurs

Giulia Biancon 15 collaborations

Toma Tebaldi 15 collaborations

Rana Gbyli 13 collaborations

Amer M Zeidan 12 collaborations

Richard A Flavell 11 collaborations

Amisha Patel 10 collaborations

Yuanbin Song 10 collaborations

Rong Fan 9 collaborations

Mina L Xu 8 collaborations

Yimeng Gao 8 collaborations

Jan Philipp Bewersdorf 7 collaborations

Jennifer VanOudenhove 7 collaborations

John Hwa 6 collaborations

Esen Sefik 6 collaborations

Steven D Gore 6 collaborations

Tae Kon Kim 6 collaborations

Dongjoo Kim 5 collaborations

Diane S Krause 5 collaborations

Alfred I Lee 5 collaborations

Hyung J Chun 5 collaborations

Matthew L Meizlish 5 collaborations

Alexander B Pine 5 collaborations

George Goshua 5 collaborations

C-Hong Chang 5 collaborations

Hanming Zhang 5 collaborations

Parveen Bahel 5 collaborations

Christina Price 5 collaborations

Jun Zhao 5 collaborations

Akiko Iwasaki 5 collaborations

Yuval Kluger 5 collaborations

Rafael Bejar 5 collaborations

Olatoyosi Odenike 5 collaborations

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Michael R Savona 5 collaborations

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