Stefan N Constantinescu

Affiliations

Ludwig Cancer Research, Brussels 1200, Belgium.
Welbio, SIGN Unit, de Duve Institute, UCLouvain, Brussels, 1200, Belgium.

Publications (9)

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization.

iScience

Avec: Florian Perrin , Nicolas Papadopoulos , Nuria Suelves , Rémi Opsomer , Devkee M Vadukul , Céline Vrancx , Steven O Smith , Didier Vertommen , Pascal Kienlen-Campard , Stefan N Constantinescu

Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions.

HemaSphere

Avec: Peter Valent , Alberto Orfao , Stefan Kubicek , Philipp Staber , Torsten Haferlach , Michael Deininger , Karoline Kollmann , Thomas Lion , Irene Virgolini , Georg Winter , Oliver Hantschel , Lukas Kenner , Johannes Zuber , Florian Grebien , Richard Moriggl , Gregor Hoermann , Olivier Hermine , Michael Andreeff , Christoph Bock , Tariq Mughal , Stefan N Constantinescu , Robert Kralovics , Veronika Sexl , Radek Skoda , Giulio Superti-Furga , Ulrich Jäger

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Cancer cell

Avec: Maurice Labuhn , Kelly Perkins , Sören Matzk , Leila Varghese , Catherine Garnett , Elli Papaemmanuil , Marlen Metzner , Alison Kennedy , Vyacheslav Amstislavskiy , Thomas Risch , Raj Bhayadia , David Samulowski , David Cruz Hernandez , Bilyana Stoilova , Valentina Iotchkova , Udo Oppermann , Carina Scheer , Kenichi Yoshida , Adrian Schwarzer , Jeffrey W Taub , John D Crispino , Mitchell J Weiss , Yasuhide Hayashi , Takashi Taga , Etsuro Ito , Seishi Ogawa , Dirk Reinhardt , Marie-Laure Yaspo , Peter J Campbell , Irene Roberts , Stefan N Constantinescu , Paresh Vyas , Dirk Heckl , Jan-Henning Klusmann

Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development.

Leukemia

Avec: Thomas Balligand , Younes Achouri , Christian Pecquet , Gilles Gaudray , Didier Colau , Eva Hug , Yacine Rahmani , Vincent Stroobant , Isabelle Plo , William Vainchenker , Robert Kralovics , Benoît J Van den Eynde , Jean-Philippe Defour , Stefan N Constantinescu

Rare type 1-like and type 2-like calreticulin mutants induce similar myeloproliferative neoplasms as prevalent type 1 and 2 mutants in mice.

Oncogene

Avec: Katte Rao Toppaldoddi , Maira da Costa Cacemiro , Olivier Bluteau , Barbara Panneau-Schmaltz , Amélie Pioch , Delphine Muller , Jean-Luc Villeval , Hana Raslova , Stefan N Constantinescu , Isabelle Plo , William Vainchenker , Caroline Marty

Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants.

Blood

Avec: Christian Pecquet , Ilyas Chachoua , Anita Roy , Thomas Balligand , Gaëlle Vertenoeil , Emilie Leroy , Roxana-Irina Albu , Jean-Philippe Defour , Harini Nivarthi , Eva Hug , Erica Xu , Yasmine Ould-Amer , Céline Mouton , Didier Colau , Didier Vertommen , Myat Marlar Shwe , Caroline Marty , Isabelle Plo , William Vainchenker , Robert Kralovics , Stefan N Constantinescu

Erratum: Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization.

iScience

Avec: Florian Perrin , Nicolas Papadopoulos , Nuria Suelves , Rémi Opsomer , Devkee M Vadukul , Céline Vrancx , Steven O Smith , Didier Vertommen , Pascal Kienlen-Campard , Stefan N Constantinescu

Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology.

Acta neuropathologica communications

Avec: Nuria Suelves , Shirine Saleki , Tasha Ibrahim , Debora Palomares , Sebastiaan Moonen , Marta J Koper , Céline Vrancx , Devkee M Vadukul , Nicolas Papadopoulos , Nikenza Viceconte , Eloïse Claude , Rik Vandenberghe , Christine A F von Arnim , Stefan N Constantinescu , Dietmar Rudolf Thal , Anabelle Decottignies , Pascal Kienlen-Campard

Recent advances in therapies for primary myelofibrosis.

Faculty reviews

Avec: William Vainchenker , Nasrine Yahmi , Violaine Havelange , Caroline Marty , Isabelle Plo , Stefan N Constantinescu

Réseau de co-auteurs

Isabelle Plo 4 collaborations

William Vainchenker 4 collaborations

Nicolas Papadopoulos 3 collaborations

Nuria Suelves 3 collaborations

Devkee M Vadukul 3 collaborations

Céline Vrancx 3 collaborations

Didier Vertommen 3 collaborations

Pascal Kienlen-Campard 3 collaborations

Robert Kralovics 3 collaborations

Caroline Marty 3 collaborations

Florian Perrin 2 collaborations

Rémi Opsomer 2 collaborations

Steven O Smith 2 collaborations

Thomas Balligand 2 collaborations

Christian Pecquet 2 collaborations

Didier Colau 2 collaborations

Eva Hug 2 collaborations

Jean-Philippe Defour 2 collaborations

Peter Valent 1 collaboration

Alberto Orfao 1 collaboration

Stefan Kubicek 1 collaboration

Philipp Staber 1 collaboration

Torsten Haferlach 1 collaboration

Michael Deininger 1 collaboration

Karoline Kollmann 1 collaboration

Thomas Lion 1 collaboration

Irene Virgolini 1 collaboration

Georg Winter 1 collaboration

Oliver Hantschel 1 collaboration

Lukas Kenner 1 collaboration

Johannes Zuber 1 collaboration

Florian Grebien 1 collaboration

Richard Moriggl 1 collaboration

Gregor Hoermann 1 collaboration

Olivier Hermine 1 collaboration

Michael Andreeff 1 collaboration

Christoph Bock 1 collaboration

Tariq Mughal 1 collaboration

Veronika Sexl 1 collaboration

Radek Skoda 1 collaboration

Giulio Superti-Furga 1 collaboration

Ulrich Jäger 1 collaboration

Maurice Labuhn 1 collaboration

Kelly Perkins 1 collaboration

Sören Matzk 1 collaboration

Leila Varghese 1 collaboration

Catherine Garnett 1 collaboration

Elli Papaemmanuil 1 collaboration

Marlen Metzner 1 collaboration

Alison Kennedy 1 collaboration

Vyacheslav Amstislavskiy 1 collaboration

Thomas Risch 1 collaboration

Raj Bhayadia 1 collaboration

David Samulowski 1 collaboration

David Cruz Hernandez 1 collaboration

Bilyana Stoilova 1 collaboration

Valentina Iotchkova 1 collaboration

Udo Oppermann 1 collaboration

Carina Scheer 1 collaboration

Kenichi Yoshida 1 collaboration

Adrian Schwarzer 1 collaboration

Jeffrey W Taub 1 collaboration

John D Crispino 1 collaboration

Mitchell J Weiss 1 collaboration

Yasuhide Hayashi 1 collaboration

Takashi Taga 1 collaboration

Etsuro Ito 1 collaboration

Seishi Ogawa 1 collaboration

Dirk Reinhardt 1 collaboration

Marie-Laure Yaspo 1 collaboration

Peter J Campbell 1 collaboration

Irene Roberts 1 collaboration

Paresh Vyas 1 collaboration

Dirk Heckl 1 collaboration

Jan-Henning Klusmann 1 collaboration

Younes Achouri 1 collaboration

Gilles Gaudray 1 collaboration

Yacine Rahmani 1 collaboration

Vincent Stroobant 1 collaboration

Benoît J Van den Eynde 1 collaboration

Katte Rao Toppaldoddi 1 collaboration

Maira da Costa Cacemiro 1 collaboration

Olivier Bluteau 1 collaboration

Barbara Panneau-Schmaltz 1 collaboration

Amélie Pioch 1 collaboration

Delphine Muller 1 collaboration

Jean-Luc Villeval 1 collaboration

Hana Raslova 1 collaboration

Ilyas Chachoua 1 collaboration

Anita Roy 1 collaboration

Gaëlle Vertenoeil 1 collaboration

Emilie Leroy 1 collaboration

Roxana-Irina Albu 1 collaboration

Harini Nivarthi 1 collaboration

Erica Xu 1 collaboration

Yasmine Ould-Amer 1 collaboration

Céline Mouton 1 collaboration

Myat Marlar Shwe 1 collaboration

Shirine Saleki 1 collaboration

Tasha Ibrahim 1 collaboration

Debora Palomares 1 collaboration

Sebastiaan Moonen 1 collaboration

Marta J Koper 1 collaboration

Nikenza Viceconte 1 collaboration

Eloïse Claude 1 collaboration

Rik Vandenberghe 1 collaboration

Christine A F von Arnim 1 collaboration

Dietmar Rudolf Thal 1 collaboration

Anabelle Decottignies 1 collaboration

Nasrine Yahmi 1 collaboration

Violaine Havelange 1 collaboration