Luca Paruzzo

Affiliations

Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USA.
Division of Hematology-Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Publications (21)

T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy.

Nature medicine

Avec: Guido Ghilardi , Joseph A Fraietta , James N Gerson , Vivianna M Van Deerlin , Jennifer J D Morrissette , Gabriel C Caponetti , Luca Paruzzo , Jaryse C Harris , Elise A Chong , Sandra P Susanibar Adaniya , Jakub Svoboda , Sunita D Nasta , Ositadimma H Ugwuanyi , Daniel J Landsburg , Eugenio Fardella , Adam J Waxman , Emeline R Chong , Vrutti Patel , Raymone Pajarillo , Irina Kulikovskaya , David B Lieberman , Adam D Cohen , Bruce L Levine , Edward A Stadtmauer , Noelle V Frey , Dan T Vogl , Elizabeth O Hexner , Stefan K Barta , David L Porter , Alfred L Garfall , Stephen J Schuster , Carl H June , Marco Ruella

Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells.

bioRxiv : the preprint server for biology

Avec: Leyuan Ma , Ranjani Ramasubramanian , Naveen K Mehta , Benjamin Cossette , Duncan M Morgan , Ina Sukaj , Elisa Bergaggio , Stephan Kadauke , Regina M Myers , Luca Paruzzo , Guido Ghilardi , Tomasz M Grzywa , Austin Cozzone , Stephen J Schuster , Noelle Frey , Libin Zhang , Parisa Yousefpour , Wuhbet Abraham , Heikyung Suh , Marco Ruella , Stephan A Grupp , Roberto Chiarle , K Dane Wittrup , Darrell J Irvine

Treatment strategies for patients with diffuse large B-cell lymphoma.

Cancer treatment reviews

Avec: Stefano Poletto , Mattia Novo , Luca Paruzzo , Pio Manlio Mirko Frascione , Umberto Vitolo

CSPG4 CAR-redirected Cytokine Induced Killer lymphocytes (CIK) as effective cellular immunotherapy for HLA class I defective melanoma.

Journal of experimental & clinical cancer research : CR

Avec: Lidia Giraudo , Giulia Cattaneo , Loretta Gammaitoni , Ilenia Iaia , Chiara Donini , Annamaria Massa , Maria Laura Centomo , Marco Basiricò , Elisa Vigna , Alberto Pisacane , Franco Picciotto , Enrico Berrino , Caterina Marchiò , Alessandra Merlini , Luca Paruzzo , Stefano Poletto , Daniela Caravelli , Andrea Michela Biolato , Valentina Bortolot , Elisa Landoni , Marco Ventin , Cristina R Ferrone , Massimo Aglietta , Gianpietro Dotti , Valeria Leuci , Fabrizio Carnevale-Schianca , Dario Sangiolo

High BRAF variant allele frequencies are associated with distinct pathological features and responsiveness to target therapy in melanoma patients.

ESMO open

Avec: E Berrino , A Balsamo , A Pisacane , S Gallo , P Becco , U Miglio , D Caravelli , S Poletto , L Paruzzo , C Debernardi , C Piccinelli , A Zaccagna , P Rescigno , M Aglietta , A Sapino , F Carnevale-Schianca , T Venesio

Streamlined measurement of chimeric antigen receptor T-cell concentration, size, viability and two-color phenotyping during manufacturing.

Cytotherapy

Avec: Raymone Pajarillo , Luca Paruzzo , Alberto Carturan , Ositadimma Ugwuanyi , Griffin White , Puneeth Guruprasad , Hatcher J Ballard , Ruchi P Patel , Yunlin Zhang , Yong Gu Lee , Seok Jae Albert Hong , Gregory M Dittami , Marco Ruella

Melanoma Brain Metastases in the Era of Target Therapies: An Overview.

Cancers

Avec: Paolo Becco , Susanna Gallo , Stefano Poletto , Mirko Pio Manlio Frascione , Luca Crotto , Alessandro Zaccagna , Luca Paruzzo , Daniela Caravelli , Fabrizio Carnevale-Schianca , Massimo Aglietta

Post-Transplant Cyclophosphamide and Tacrolimus-Mycophenolate Mofetil Combination Governs GVHD and Immunosuppression Need, Reducing Late Toxicities in Allogeneic Peripheral Blood Hematopoietic Cell Transplantation from HLA-Matched Donors.

Journal of clinical medicine

Avec: Fabrizio Carnevale-Schianca , Daniela Caravelli , Susanna Gallo , Paolo Becco , Luca Paruzzo , Stefano Poletto , Alessandra Polo , Monica Mangioni , Milena Salierno , Massimo Berger , Rosanna Pessolano , Francesco Saglio , Daniela Gottardi , Delia Rota-Scalabrini , Giovanni Grignani , Marco Fizzotti , Ivana Ferrero , Pio Manlio Mirko Frascione , Lorenzo D'Ambrosio , Valentina Gaidano , Loretta Gammaitoni , Dario Sangiolo , Andrea Saglietto , Elena Vassallo , Alessandro Cignetti , Massimo Aglietta , Franca Fagioli

Bendamustine Lymphodepletion Before Axicabtagene Ciloleucel Is Safe and Associates with Reduced Inflammatory Cytokines.

Blood advances

Avec: Guido Ghilardi , Luca Paruzzo , Jakub Svoboda , Elise A Chong , Alexander A Shestov , Linhui Chen , Ivan J Cohen , Giulia Gabrielli , Sunita D Nasta , Patrizia Porazzi , Daniel J Landsburg , James N Gerson , Jordan Carter , Stefan K Barta , Rebecca Dawn Yelton , Raymone Pajarillo , Vrutti Patel , Griffin White , Hatcher Ballard , Elizabeth Weber , Ellen B Napier , Emeline R Chong , Joseph A Fraietta , Alfred Garfall , David L Porter , Michael C Milone , Roddy S O'Connor , Stephen J Schuster , Marco Ruella

The BTLA-HVEM axis restricts CAR T cell efficacy in cancer.

Nature immunology

Avec: Puneeth Guruprasad , Alberto Carturan , Yunlin Zhang , Jong Hyun Cho , Kingsley Gideon Kumashie , Ruchi P Patel , Ki-Hyun Kim , Jong-Seo Lee , Yoon Lee , Jong Hoon Kim , Junho Chung , Akshita Joshi , Ivan Cohen , Maksim Shestov , Guido Ghilardi , Jaryse Harris , Raymone Pajarillo , Mathew Angelos , Yong Gu Lee , Shan Liu , Jesse Rodriguez , Michael Wang , Hatcher J Ballard , Aasha Gupta , Ositadimma H Ugwuanyi , Seok Jae Albert Hong , Audrey C Bochi-Layec , Christopher T Sauter , Linhui Chen , Luca Paruzzo , Shane Kammerman , Olga Shestova , Dongfang Liu , Laura A Vella , Stephen J Schuster , Jakub Svoboda , Patrizia Porazzi , Marco Ruella

Current Controversies and Challenges on BRAF V600K-Mutant Cutaneous Melanoma.

Journal of clinical medicine

Avec: Alessandro Nepote , Gianluca Avallone , Simone Ribero , Francesco Cavallo , Gabriele Roccuzzo , Luca Mastorino , Claudio Conforti , Luca Paruzzo , Stefano Poletto , Fabrizio Carnevale Schianca , Pietro Quaglino , Massimo Aglietta

Apoptosis: a

Journal for immunotherapy of cancer

Avec: Yong Gu Lee , Nicholas Yang , Inkook Chun , Patrizia Porazzi , Alberto Carturan , Luca Paruzzo , Christopher Tor Sauter , Puneeth Guruprasad , Raymone Pajarillo , Marco Ruella

Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies.

Blood

Avec: Zhiwei Ang , Luca Paruzzo , Katharina E Hayer , Carolin Schmidt , Manuel Torres Diz , Feng Xu , Urvi Zankharia , Yunlin Zhang , Samantha Soldan , Sisi Zheng , Catherine D Falkenstein , Joseph P Loftus , Scarlett Y Yang , Mukta Asnani , Patricia King Sainos , Vinodh Pillai , Emeline Chong , Marilyn M Li , Sarah K Tasian , Yoseph Barash , Paul M Lieberman , Marco Ruella , Stephen J Schuster , Andrei Thomas-Tikhonenko

Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies.

bioRxiv : the preprint server for biology

Predictive Factors in Metastatic Melanoma Treated with Immune Checkpoint Inhibitors: From Clinical Practice to Future Perspective.

Cancers

Avec: Stefano Poletto , Luca Paruzzo , Alessandro Nepote , Daniela Caravelli , Dario Sangiolo , Fabrizio Carnevale-Schianca

Bendamustine as lymphodepletion for brexucabtagene autoleucel therapy of mantle cell lymphoma.

Transplantation and cellular therapy

Avec: Elise A Chong , Emeline R Chong , Dylan Therwhangher , Sunita D Nasta , Daniel J Landsburg , Stefan K Barta , Jakub Svoboda , James N Gerson , Guido Ghilardi , Luca Paruzzo , Joseph A Fraietta , Elizabeth Weber , Natalie Stefano , David L Porter , Noelle V Frey , Alfred L Garfall , Marco Ruella , Stephen J Schuster

Efficacy and safety of bendamustine for lymphodepletion before lisocabtagene maraleucel.

Journal of hematology & oncology

Avec: Guido Ghilardi , Luca Paruzzo , Vrutti Patel , Jakub Svoboda , Emeline R Chong , Eugenio Fardella , Elise A Chong , Giulia Gabrielli , Sunita D Nasta , Daniel J Landsburg , Jordan Carter , Raymone Pajarillo , Stefan K Barta , Griffin White , Elizabeth Weber , Ellen Napier , David L Porter , Alfred L Garfall , Stephen J Schuster , Marco Ruella

Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study.

Molecular cancer

Avec: Yunlin Zhang , Ruchi P Patel , Ki Hyun Kim , Hyungwoo Cho , Jae-Cheol Jo , Seong Hyun Jeong , Sung Yong Oh , Yoon Seok Choi , Sung Hyun Kim , Ji Hyun Lee , Mathew Angelos , Puneeth Guruprasad , Ivan Cohen , Ositadimma Ugwuanyi , Yong Gu Lee , Raymone Pajarillo , Jong Hyun Cho , Alberto Carturan , Luca Paruzzo , Guido Ghilardi , Michael Wang , Soohwan Kim , Sung-Min Kim , Hyun-Jong Lee , Ji-Ho Park , Leiguang Cui , Tae Bum Lee , In-Sik Hwang , Young-Ha Lee , Yong-Jun Lee , Patrizia Porazzi , Dongfang Liu , Yoon Lee , Jong-Hoon Kim , Jong-Seo Lee , Dok Hyun Yoon , Junho Chung , Marco Ruella

CAR T-Cell Immunotherapy in Minority Patients with Lymphoma.

NEJM evidence

Avec: Guido Ghilardi , Staci Williamson , Raymone Pajarillo , Luca Paruzzo , Linhui Chen , Connor Grady , Abigail Doucette , Eneida Nemecek , Giulia Gabrielli , Stefan K Barta , Jakub Svoboda , Elise A Chong , Rebecca Yelton , Sunita D Nasta , Daniel J Landsburg , Ositadimma Ugwuanyi , Andy I Chen , Levanto Schachter , Griffin White , Hatcher J Ballard , Elizabeth Weber , Cara Curley , David L Porter , Alfred L Garfall , Wei-Ting Hwang , Carmen E Guerra , Richard T Maziarz , Stephen J Schuster , Marco Ruella

CD5 deletion enhances the antitumor activity of adoptive T cell therapies.

Science immunology

Avec: Ruchi P Patel , Guido Ghilardi , Yunlin Zhang , Yi-Hao Chiang , Wei Xie , Puneeth Guruprasad , Ki Hyun Kim , Inkook Chun , Mathew G Angelos , Raymone Pajarillo , Seok Jae Hong , Yong Gu Lee , Olga Shestova , Carolyn Shaw , Ivan Cohen , Aasha Gupta , Trang Vu , Dean Qian , Steven Yang , Aditya Nimmagadda , Adam E Snook , Nicholas Siciliano , Antonia Rotolo , Arati Inamdar , Jaryse Harris , Ositadimma Ugwuanyi , Michael Wang , Alberto Carturan , Luca Paruzzo , Linhui Chen , Hatcher J Ballard , Tatiana Blanchard , Chong Xu , Mohamed Abdel-Mohsen , Khatuna Gabunia , Maria Wysocka , Gerald P Linette , Beatriz Carreno , David M Barrett , David T Teachey , Avery D Posey , Daniel J Powell , C Tor Sauter , Stefano Pileri , Vinodh Pillai , John Scholler , Alain H Rook , Stephen J Schuster , Stefan K Barta , Patrizia Porazzi , Marco Ruella

Recent Advances in Immune-Based Therapies for Acute Myeloid Leukemia.

Blood cancer discovery

Avec: Cecilia Restelli , Marco Ruella , Luca Paruzzo , Corrado Tarella , Pier Giuseppe Pelicci , Emanuela Colombo

Réseau de co-auteurs

Marco Ruella 14 collaborations

Stephen J Schuster 10 collaborations

Guido Ghilardi 9 collaborations

Raymone Pajarillo 9 collaborations

Jakub Svoboda 6 collaborations

Stefan K Barta 6 collaborations

Stefano Poletto 6 collaborations

Yunlin Zhang 6 collaborations

Elise A Chong 5 collaborations

Sunita D Nasta 5 collaborations

Daniel J Landsburg 5 collaborations

David L Porter 5 collaborations

Alberto Carturan 5 collaborations

Puneeth Guruprasad 5 collaborations

Yong Gu Lee 5 collaborations

Patrizia Porazzi 5 collaborations

Emeline R Chong 4 collaborations

Alfred L Garfall 4 collaborations

Daniela Caravelli 4 collaborations

Massimo Aglietta 4 collaborations

Fabrizio Carnevale-Schianca 4 collaborations

Ositadimma Ugwuanyi 4 collaborations

Griffin White 4 collaborations

Hatcher J Ballard 4 collaborations

Ruchi P Patel 4 collaborations

Linhui Chen 4 collaborations

Elizabeth Weber 4 collaborations

Joseph A Fraietta 3 collaborations

James N Gerson 3 collaborations

Vrutti Patel 3 collaborations

Dario Sangiolo 3 collaborations

Giulia Gabrielli 3 collaborations

Ivan Cohen 3 collaborations

Michael Wang 3 collaborations

Vinodh Pillai 3 collaborations

Ositadimma H Ugwuanyi 2 collaborations

Eugenio Fardella 2 collaborations

Noelle V Frey 2 collaborations

Pio Manlio Mirko Frascione 2 collaborations

Loretta Gammaitoni 2 collaborations

Seok Jae Albert Hong 2 collaborations

Paolo Becco 2 collaborations

Susanna Gallo 2 collaborations

Jordan Carter 2 collaborations

Jong Hyun Cho 2 collaborations

Jong-Seo Lee 2 collaborations

Yoon Lee 2 collaborations

Junho Chung 2 collaborations

Jaryse Harris 2 collaborations

Mathew Angelos 2 collaborations

Aasha Gupta 2 collaborations

Olga Shestova 2 collaborations

Dongfang Liu 2 collaborations

Alessandro Nepote 2 collaborations

Inkook Chun 2 collaborations

Zhiwei Ang 2 collaborations

Katharina E Hayer 2 collaborations

Carolin Schmidt 2 collaborations

Manuel Torres Diz 2 collaborations

Feng Xu 2 collaborations

Urvi Zankharia 2 collaborations

Samantha Soldan 2 collaborations

Sisi Zheng 2 collaborations

Catherine D Falkenstein 2 collaborations

Joseph P Loftus 2 collaborations

Scarlett Y Yang 2 collaborations

Mukta Asnani 2 collaborations

Patricia King Sainos 2 collaborations

Emeline Chong 2 collaborations

Marilyn M Li 2 collaborations

Sarah K Tasian 2 collaborations

Yoseph Barash 2 collaborations

Paul M Lieberman 2 collaborations

Andrei Thomas-Tikhonenko 2 collaborations

Ki Hyun Kim 2 collaborations

Vivianna M Van Deerlin 1 collaboration

Jennifer J D Morrissette 1 collaboration

Gabriel C Caponetti 1 collaboration

Jaryse C Harris 1 collaboration

Sandra P Susanibar Adaniya 1 collaboration

Adam J Waxman 1 collaboration

Irina Kulikovskaya 1 collaboration

David B Lieberman 1 collaboration

Adam D Cohen 1 collaboration

Bruce L Levine 1 collaboration

Edward A Stadtmauer 1 collaboration

Dan T Vogl 1 collaboration

Elizabeth O Hexner 1 collaboration

Carl H June 1 collaboration

Leyuan Ma 1 collaboration

Ranjani Ramasubramanian 1 collaboration

Naveen K Mehta 1 collaboration

Benjamin Cossette 1 collaboration

Duncan M Morgan 1 collaboration

Ina Sukaj 1 collaboration

Elisa Bergaggio 1 collaboration

Stephan Kadauke 1 collaboration

Regina M Myers 1 collaboration

Tomasz M Grzywa 1 collaboration

Austin Cozzone 1 collaboration

Noelle Frey 1 collaboration

Libin Zhang 1 collaboration

Parisa Yousefpour 1 collaboration

Wuhbet Abraham 1 collaboration

Heikyung Suh 1 collaboration

Stephan A Grupp 1 collaboration

Roberto Chiarle 1 collaboration

K Dane Wittrup 1 collaboration

Darrell J Irvine 1 collaboration

Mattia Novo 1 collaboration

Umberto Vitolo 1 collaboration

Lidia Giraudo 1 collaboration

Giulia Cattaneo 1 collaboration

Ilenia Iaia 1 collaboration

Chiara Donini 1 collaboration

Annamaria Massa 1 collaboration

Maria Laura Centomo 1 collaboration

Marco Basiricò 1 collaboration

Elisa Vigna 1 collaboration

Alberto Pisacane 1 collaboration

Franco Picciotto 1 collaboration

Enrico Berrino 1 collaboration

Caterina Marchiò 1 collaboration

Alessandra Merlini 1 collaboration

Andrea Michela Biolato 1 collaboration

Valentina Bortolot 1 collaboration

Elisa Landoni 1 collaboration

Marco Ventin 1 collaboration

Cristina R Ferrone 1 collaboration

Gianpietro Dotti 1 collaboration

Valeria Leuci 1 collaboration

E Berrino 1 collaboration

A Balsamo 1 collaboration

A Pisacane 1 collaboration

S Gallo 1 collaboration

P Becco 1 collaboration

U Miglio 1 collaboration

D Caravelli 1 collaboration

S Poletto 1 collaboration

L Paruzzo 1 collaboration

C Debernardi 1 collaboration

C Piccinelli 1 collaboration

A Zaccagna 1 collaboration

P Rescigno 1 collaboration

M Aglietta 1 collaboration

A Sapino 1 collaboration

F Carnevale-Schianca 1 collaboration

T Venesio 1 collaboration

Gregory M Dittami 1 collaboration

Mirko Pio Manlio Frascione 1 collaboration

Luca Crotto 1 collaboration

Alessandro Zaccagna 1 collaboration

Alessandra Polo 1 collaboration

Monica Mangioni 1 collaboration

Milena Salierno 1 collaboration

Massimo Berger 1 collaboration

Rosanna Pessolano 1 collaboration

Francesco Saglio 1 collaboration

Daniela Gottardi 1 collaboration

Delia Rota-Scalabrini 1 collaboration

Giovanni Grignani 1 collaboration

Marco Fizzotti 1 collaboration

Ivana Ferrero 1 collaboration

Lorenzo D'Ambrosio 1 collaboration

Valentina Gaidano 1 collaboration

Andrea Saglietto 1 collaboration

Elena Vassallo 1 collaboration

Alessandro Cignetti 1 collaboration

Franca Fagioli 1 collaboration

Alexander A Shestov 1 collaboration

Ivan J Cohen 1 collaboration

Rebecca Dawn Yelton 1 collaboration

Hatcher Ballard 1 collaboration

Ellen B Napier 1 collaboration

Alfred Garfall 1 collaboration

Michael C Milone 1 collaboration

Roddy S O'Connor 1 collaboration

Kingsley Gideon Kumashie 1 collaboration

Ki-Hyun Kim 1 collaboration

Jong Hoon Kim 1 collaboration

Akshita Joshi 1 collaboration

Maksim Shestov 1 collaboration

Shan Liu 1 collaboration

Jesse Rodriguez 1 collaboration

Audrey C Bochi-Layec 1 collaboration

Christopher T Sauter 1 collaboration

Shane Kammerman 1 collaboration

Laura A Vella 1 collaboration

Gianluca Avallone 1 collaboration

Simone Ribero 1 collaboration

Francesco Cavallo 1 collaboration

Gabriele Roccuzzo 1 collaboration

Luca Mastorino 1 collaboration

Claudio Conforti 1 collaboration

Fabrizio Carnevale Schianca 1 collaboration

Pietro Quaglino 1 collaboration

Nicholas Yang 1 collaboration

Christopher Tor Sauter 1 collaboration

Dylan Therwhangher 1 collaboration

Natalie Stefano 1 collaboration

Ellen Napier 1 collaboration

Hyungwoo Cho 1 collaboration

Jae-Cheol Jo 1 collaboration

Seong Hyun Jeong 1 collaboration

Sung Yong Oh 1 collaboration

Yoon Seok Choi 1 collaboration

Sung Hyun Kim 1 collaboration

Ji Hyun Lee 1 collaboration

Soohwan Kim 1 collaboration

Sung-Min Kim 1 collaboration

Hyun-Jong Lee 1 collaboration

Ji-Ho Park 1 collaboration

Leiguang Cui 1 collaboration

Tae Bum Lee 1 collaboration

In-Sik Hwang 1 collaboration

Young-Ha Lee 1 collaboration

Yong-Jun Lee 1 collaboration

Jong-Hoon Kim 1 collaboration

Dok Hyun Yoon 1 collaboration

Staci Williamson 1 collaboration

Connor Grady 1 collaboration

Abigail Doucette 1 collaboration

Eneida Nemecek 1 collaboration

Rebecca Yelton 1 collaboration

Andy I Chen 1 collaboration

Levanto Schachter 1 collaboration

Cara Curley 1 collaboration

Wei-Ting Hwang 1 collaboration

Carmen E Guerra 1 collaboration

Richard T Maziarz 1 collaboration

Yi-Hao Chiang 1 collaboration

Wei Xie 1 collaboration

Mathew G Angelos 1 collaboration

Seok Jae Hong 1 collaboration

Carolyn Shaw 1 collaboration

Trang Vu 1 collaboration

Dean Qian 1 collaboration

Steven Yang 1 collaboration

Aditya Nimmagadda 1 collaboration

Adam E Snook 1 collaboration

Nicholas Siciliano 1 collaboration

Antonia Rotolo 1 collaboration

Arati Inamdar 1 collaboration

Tatiana Blanchard 1 collaboration

Chong Xu 1 collaboration

Mohamed Abdel-Mohsen 1 collaboration

Khatuna Gabunia 1 collaboration

Maria Wysocka 1 collaboration

Gerald P Linette 1 collaboration

Beatriz Carreno 1 collaboration

David M Barrett 1 collaboration

David T Teachey 1 collaboration

Avery D Posey 1 collaboration

Daniel J Powell 1 collaboration

C Tor Sauter 1 collaboration

Stefano Pileri 1 collaboration

John Scholler 1 collaboration

Alain H Rook 1 collaboration

Cecilia Restelli 1 collaboration

Corrado Tarella 1 collaboration

Pier Giuseppe Pelicci 1 collaboration

Emanuela Colombo 1 collaboration