M Isabel Loza

Affiliations

Innopharma Screening Platform, Biofarma Research Group, Centre of Research in Molecular Medicine and Chronic Diseases (CIMUS) , University of Santiago de Compostela , E-15782 Santiago de Compostela , Spain.

Publications (24)

Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6.

Journal of medicinal chemistry

Avec: F Javier Pérez-Areales , María Garrido , Ester Aso , Manuela Bartolini , Angela De Simone , Alba Espargaró , Tiziana Ginex , Raimon Sabate , Belén Pérez , Vincenza Andrisano , Dolors Puigoriol-Illamola , Mercè Pallàs , F Javier Luque , María Isabel Loza , José Brea , Isidro Ferrer , Francisco Ciruela , Angel Messeguer , Diego Muñoz-Torrero

Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays.

International journal of molecular sciences

Avec: Cristian O Salas , Ana Maria Zarate , Vladimir Kryštof , Jaime Mella , Mario Faundez , Jose Brea , María Isabel Loza , Ivan Brito , Denisa Hendrychová , Radek Jorda , Alan R Cabrera , Ricardo A Tapia , Christian Espinosa-Bustos

A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade.

Thrombosis and haemostasis

Avec: Irene Izquierdo , María N Barrachina , Lidia Hermida-Nogueira , Vanessa Casas , Luis A Morán , Serena Lacerenza , Roberto Pinto-Llorente , Johannes A Eble , Vivian de Los Ríos , Eduardo Domínguez , María I Loza , José Ignacio Casal , Montserrat Carrascal , Joaquín Abián , Angel García

2-Aryladenine derivatives as a potent scaffold for A

Bioorganic & medicinal chemistry

Avec: Filipe Areias , Carla Correia , Ashly Rocha , José Brea , Marián Castro , Maria I Loza , M Fernanda Proença , M Alice Carvalho

Trifluorinated Pyrimidine-Based A

Journal of medicinal chemistry

Avec: Ana Mallo-Abreu , María Majellaro , Willem Jespers , Jhonny Azuaje , Olga Caamaño , Xerardo García-Mera , José M Brea , María I Loza , Hugo Gutiérrez-de-Terán , Eddy Sotelo

Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation.

European journal of medicinal chemistry

Avec: Andrea Astolfi , Mark Kudolo , Jose Brea , Giorgia Manni , Giuseppe Manfroni , Deborah Palazzotti , Stefano Sabatini , Federica Cecchetti , Tommaso Felicetti , Rolando Cannalire , Serena Massari , Oriana Tabarrini , Maria Isabel Loza , Francesca Fallarino , Violetta Cecchetti , Stefan A Laufer , Maria Letizia Barreca

Synthesis, Pharmacological, and Biological Evaluation of MIF-1 Picolinoyl Peptidomimetics as Positive Allosteric Modulators of D

ACS chemical neuroscience

Avec: Ivo E Sampaio-Dias , Sara C Silva-Reis , Xerardo García-Mera , José Brea , M Isabel Loza , Carla S Alves , Manuel Algarra , José E Rodríguez-Borges

From the Design to the

Journal of medicinal chemistry

Avec: Sandra Codony , Carla Calvó-Tusell , Elena Valverde , Sílvia Osuna , Christophe Morisseau , M Isabel Loza , José Brea , Concepción Pérez , María Isabel Rodríguez-Franco , Javier Pizarro-Delgado , Rubén Corpas , Christian Griñán-Ferré , Mercè Pallàs , Coral Sanfeliu , Manuel Vázquez-Carrera , Bruce D Hammock , Ferran Feixas , Santiago Vázquez

Knowledge-Based Design of Long-Chain Arylpiperazine Derivatives Targeting Multiple Serotonin Receptors as Potential Candidates for Treatment of Autism Spectrum Disorder.

ACS chemical neuroscience

Avec: Enza Lacivita , Mauro Niso , Margherita Mastromarino , Andrea Garcia Silva , Cibell Resch , Andre Zeug , María I Loza , Marián Castro , Evgeni Ponimaskin , Marcello Leopoldo

2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity.

Pharmaceuticals (Basel, Switzerland)

Avec: Juan Martín-López , Sandra Codony , Clara Bartra , Christophe Morisseau , María Isabel Loza , Coral Sanfeliu , Bruce D Hammock , José Brea , Santiago Vázquez

Katacine Is a New Ligand of CLEC-2 that Acts as a Platelet Agonist.

Thrombosis and haemostasis

Avec: Luis A Morán , Ying Di , Marcin A Sowa , Lidia Hermida-Nogueira , María N Barrachina , Eleyna Martin , Joanne C Clark , Todd H Mize , Johannes A Eble , David Moreira , Alice Y Pollitt , María I Loza , Eduardo Domínguez , Steve P Watson , Ángel García

Exploring Non-orthosteric Interactions with a Series of Potent and Selective A

ACS medicinal chemistry letters

Avec: Darío Miranda-Pastoriza , Rodrigo Bernárdez , Jhonny Azuaje , Rubén Prieto-Díaz , Maria Majellaro , Ashish V Tamhankar , Lucien Koenekoop , Alejandro González , Claudia Gioé-Gallo , Ana Mallo-Abreu , José Brea , M Isabel Loza , Aitor García-Rey , Xerardo García-Mera , Hugo Gutiérrez-de-Terán , Eddy Sotelo

Novel Pyridazin-3(2

ACS medicinal chemistry letters

Avec: María Carmen Costas-Lago , Noemí Vila , Adeyemi Rahman , Pedro Besada , Isabel Rozas , José Brea , María Isabel Loza , Elisa González-Romero , Carmen Terán

From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-

Pharmaceutics

Avec: Andrea Astolfi , Francesca Milano , Deborah Palazzotti , Jose Brea , Maria Chiara Pismataro , Mariangela Morlando , Oriana Tabarrini , Maria Isabel Loza , Serena Massari , Maria Paola Martelli , Maria Letizia Barreca

Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models.

Nature communications

Avec: Luis Filipe Costa-Machado , Esther Garcia-Dominguez , Rebecca L McIntyre , Jose Luis Lopez-Aceituno , Álvaro Ballesteros-Gonzalez , Andrea Tapia-Gonzalez , David Fabregat-Safont , Tobias Eisenberg , Jesús Gomez , Adrian Plaza , Aranzazu Sierra-Ramirez , Manuel Perez , David Villanueva-Bermejo , Tiziana Fornari , María Isabel Loza , Gonzalo Herradon , Sebastian J Hofer , Christoph Magnes , Frank Madeo , Janet S Duerr , Oscar J Pozo , Maximo-Ibo Galindo , Isabel Del Pino , Riekelt H Houtkooper , Diego Megias , Jose Viña , Mari Carmen Gomez-Cabrera , Pablo J Fernandez-Marcos

Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D

ACS medicinal chemistry letters

Avec: Sara C Silva-Reis , Xavier C Correia , Hugo F Costa-Almeida , Beatriz L Pires-Lima , Daiane Maronde , Vera M Costa , Xerardo García-Mera , Luís Cruz , José Brea , María Isabel Loza , José E Rodríguez-Borges , Ivo E Sampaio-Dias

G protein-specific mechanisms in the serotonin 5-HT

Nature communications

Avec: Elk Kossatz , Rebeca Diez-Alarcia , Supriya A Gaitonde , Carla Ramon-Duaso , Tomasz Maciej Stepniewski , David Aranda-Garcia , Itziar Muneta-Arrate , Elodie Tepaz , Suwipa Saen-Oon , Robert Soliva , Aida Shahraki , David Moreira , Jose Brea , Maria Isabel Loza , Rafael de la Torre , Peter Kolb , Michel Bouvier , J Javier Meana , Patricia Robledo , Jana Selent

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice.

Pharmaceutics

Avec: Júlia Companys-Alemany , Andreea L Turcu , Aina Bellver-Sanchis , Maria I Loza , José M Brea , Anna M Canudas , Rosana Leiva , Santiago Vázquez , Mercè Pallàs , Christian Griñán-Ferré

Dibenzofuranylethylamines as 5-HT

ACS omega

Avec: Thirumal Yempala , José Brea , María Isabel Loza , Douglas J Matthies , Gerald Zapata-Torres , Bruce K Cassels

His452Tyr polymorphism in the human 5-HT

Biochemical pharmacology

Avec: Sandra M Martín-Guerrero , Paula Alonso , Alba Iglesias , Marta Cimadevila , José Brea , M Isabel Loza , Pedro Casado , David Martín-Oliva , Pedro R Cutillas , Javier González-Maeso , Juan F López-Giménez

Author Correction: Identification and characterization of Cardiac Glycosides as senolytic compounds.

Nature communications

Avec: Francisco Triana-Martínez , Pilar Picallos-Rabina , Sabela Da Silva-Álvarez , Federico Pietrocola , Susana Llanos , Verónica Rodilla , Enrica Soprano , Pablo Pedrosa , Alba Ferreirós , Marta Barradas , Fernanda Hernández-González , Marta Lalinde , Neus Prats , Cristina Bernadó , Patricia González , María Gómez , Maria P Ikonomopoulou , Pablo J Fernández-Marcos , Tomás García-Caballero , Pablo Del Pino , Joaquín Arribas , Anxo Vidal , Miguel González-Barcia , Manuel Serrano , María I Loza , Eduardo Domínguez , Manuel Collado

Identification of Novel Regulators of Zalcitabine-Induced Neuropathic Pain.

ACS chemical neuroscience

Avec: Antón L Martínez , José Brea , Eduardo Domínguez , María J Varela , Marta Cimadevila , Catarina Allegue , Raquel Cruz , Xavier Monroy , Manuel Merlos , Javier Burgueño , Ángel Carracedo , María I Loza

Effect of Bulky

ACS chemical neuroscience

Avec: Breno A Soares , Thirumal Yempala , Darío Martínez-Afani , Williams Acevedo-Fuentes , José Brea , María Isabel Loza , Marta Cimadevila , Bruce K Cassels

A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.

Molecules (Basel, Switzerland)

Avec: Gemma Navarro , Eddy Sotelo , Iu Raïch , María Isabel Loza , Jose Brea , Maria Majellaro

Réseau de co-auteurs

José Brea 12 collaborations

María Isabel Loza 9 collaborations

María I Loza 6 collaborations

Jose Brea 5 collaborations

Eduardo Domínguez 4 collaborations

Xerardo García-Mera 4 collaborations

Mercè Pallàs 3 collaborations

Eddy Sotelo 3 collaborations

Maria Isabel Loza 3 collaborations

Santiago Vázquez 3 collaborations

Marta Cimadevila 3 collaborations

María N Barrachina 2 collaborations

Lidia Hermida-Nogueira 2 collaborations

Luis A Morán 2 collaborations

Johannes A Eble 2 collaborations

Marián Castro 2 collaborations

Maria I Loza 2 collaborations

Ana Mallo-Abreu 2 collaborations

Jhonny Azuaje 2 collaborations

José M Brea 2 collaborations

Hugo Gutiérrez-de-Terán 2 collaborations

Andrea Astolfi 2 collaborations

Deborah Palazzotti 2 collaborations

Serena Massari 2 collaborations

Oriana Tabarrini 2 collaborations

Maria Letizia Barreca 2 collaborations

Ivo E Sampaio-Dias 2 collaborations

Sara C Silva-Reis 2 collaborations

José E Rodríguez-Borges 2 collaborations

Sandra Codony 2 collaborations

Christophe Morisseau 2 collaborations

Christian Griñán-Ferré 2 collaborations

Coral Sanfeliu 2 collaborations

Bruce D Hammock 2 collaborations

David Moreira 2 collaborations

Maria Majellaro 2 collaborations

Thirumal Yempala 2 collaborations

Bruce K Cassels 2 collaborations

F Javier Pérez-Areales 1 collaboration

María Garrido 1 collaboration

Ester Aso 1 collaboration

Manuela Bartolini 1 collaboration

Angela De Simone 1 collaboration

Alba Espargaró 1 collaboration

Tiziana Ginex 1 collaboration

Raimon Sabate 1 collaboration

Belén Pérez 1 collaboration

Vincenza Andrisano 1 collaboration

Dolors Puigoriol-Illamola 1 collaboration

F Javier Luque 1 collaboration

Isidro Ferrer 1 collaboration

Francisco Ciruela 1 collaboration

Angel Messeguer 1 collaboration

Diego Muñoz-Torrero 1 collaboration

Cristian O Salas 1 collaboration

Ana Maria Zarate 1 collaboration

Vladimir Kryštof 1 collaboration

Jaime Mella 1 collaboration

Mario Faundez 1 collaboration

Ivan Brito 1 collaboration

Denisa Hendrychová 1 collaboration

Radek Jorda 1 collaboration

Alan R Cabrera 1 collaboration

Ricardo A Tapia 1 collaboration

Christian Espinosa-Bustos 1 collaboration

Irene Izquierdo 1 collaboration

Vanessa Casas 1 collaboration

Serena Lacerenza 1 collaboration

Roberto Pinto-Llorente 1 collaboration

Vivian de Los Ríos 1 collaboration

José Ignacio Casal 1 collaboration

Montserrat Carrascal 1 collaboration

Joaquín Abián 1 collaboration

Angel García 1 collaboration

Filipe Areias 1 collaboration

Carla Correia 1 collaboration

Ashly Rocha 1 collaboration

M Fernanda Proença 1 collaboration

M Alice Carvalho 1 collaboration

María Majellaro 1 collaboration

Willem Jespers 1 collaboration

Olga Caamaño 1 collaboration

Mark Kudolo 1 collaboration

Giorgia Manni 1 collaboration

Giuseppe Manfroni 1 collaboration

Stefano Sabatini 1 collaboration

Federica Cecchetti 1 collaboration

Tommaso Felicetti 1 collaboration

Rolando Cannalire 1 collaboration

Francesca Fallarino 1 collaboration

Violetta Cecchetti 1 collaboration

Stefan A Laufer 1 collaboration

Carla S Alves 1 collaboration

Manuel Algarra 1 collaboration

Carla Calvó-Tusell 1 collaboration

Elena Valverde 1 collaboration

Sílvia Osuna 1 collaboration

Concepción Pérez 1 collaboration

María Isabel Rodríguez-Franco 1 collaboration

Javier Pizarro-Delgado 1 collaboration

Rubén Corpas 1 collaboration

Manuel Vázquez-Carrera 1 collaboration

Ferran Feixas 1 collaboration

Enza Lacivita 1 collaboration

Mauro Niso 1 collaboration

Margherita Mastromarino 1 collaboration

Andrea Garcia Silva 1 collaboration

Cibell Resch 1 collaboration

Andre Zeug 1 collaboration

Evgeni Ponimaskin 1 collaboration

Marcello Leopoldo 1 collaboration

Juan Martín-López 1 collaboration

Clara Bartra 1 collaboration

Ying Di 1 collaboration

Marcin A Sowa 1 collaboration

Eleyna Martin 1 collaboration

Joanne C Clark 1 collaboration

Todd H Mize 1 collaboration

Alice Y Pollitt 1 collaboration

Steve P Watson 1 collaboration

Ángel García 1 collaboration

Darío Miranda-Pastoriza 1 collaboration

Rodrigo Bernárdez 1 collaboration

Rubén Prieto-Díaz 1 collaboration

Ashish V Tamhankar 1 collaboration

Lucien Koenekoop 1 collaboration

Alejandro González 1 collaboration

Claudia Gioé-Gallo 1 collaboration

Aitor García-Rey 1 collaboration

María Carmen Costas-Lago 1 collaboration

Noemí Vila 1 collaboration

Adeyemi Rahman 1 collaboration

Pedro Besada 1 collaboration

Isabel Rozas 1 collaboration

Elisa González-Romero 1 collaboration

Carmen Terán 1 collaboration

Francesca Milano 1 collaboration

Maria Chiara Pismataro 1 collaboration

Mariangela Morlando 1 collaboration

Maria Paola Martelli 1 collaboration

Luis Filipe Costa-Machado 1 collaboration

Esther Garcia-Dominguez 1 collaboration

Rebecca L McIntyre 1 collaboration

Jose Luis Lopez-Aceituno 1 collaboration

Álvaro Ballesteros-Gonzalez 1 collaboration

Andrea Tapia-Gonzalez 1 collaboration

David Fabregat-Safont 1 collaboration

Tobias Eisenberg 1 collaboration

Jesús Gomez 1 collaboration

Adrian Plaza 1 collaboration

Aranzazu Sierra-Ramirez 1 collaboration

Manuel Perez 1 collaboration

David Villanueva-Bermejo 1 collaboration

Tiziana Fornari 1 collaboration

Gonzalo Herradon 1 collaboration

Sebastian J Hofer 1 collaboration

Christoph Magnes 1 collaboration

Frank Madeo 1 collaboration

Janet S Duerr 1 collaboration

Oscar J Pozo 1 collaboration

Maximo-Ibo Galindo 1 collaboration

Isabel Del Pino 1 collaboration

Riekelt H Houtkooper 1 collaboration

Diego Megias 1 collaboration

Jose Viña 1 collaboration

Mari Carmen Gomez-Cabrera 1 collaboration

Pablo J Fernandez-Marcos 1 collaboration

Xavier C Correia 1 collaboration

Hugo F Costa-Almeida 1 collaboration

Beatriz L Pires-Lima 1 collaboration

Daiane Maronde 1 collaboration

Vera M Costa 1 collaboration

Luís Cruz 1 collaboration

Elk Kossatz 1 collaboration

Rebeca Diez-Alarcia 1 collaboration

Supriya A Gaitonde 1 collaboration

Carla Ramon-Duaso 1 collaboration

Tomasz Maciej Stepniewski 1 collaboration

David Aranda-Garcia 1 collaboration

Itziar Muneta-Arrate 1 collaboration

Elodie Tepaz 1 collaboration

Suwipa Saen-Oon 1 collaboration

Robert Soliva 1 collaboration

Aida Shahraki 1 collaboration

Rafael de la Torre 1 collaboration

Peter Kolb 1 collaboration

Michel Bouvier 1 collaboration

J Javier Meana 1 collaboration

Patricia Robledo 1 collaboration

Jana Selent 1 collaboration

Júlia Companys-Alemany 1 collaboration

Andreea L Turcu 1 collaboration

Aina Bellver-Sanchis 1 collaboration

Anna M Canudas 1 collaboration

Rosana Leiva 1 collaboration

Douglas J Matthies 1 collaboration

Gerald Zapata-Torres 1 collaboration

Sandra M Martín-Guerrero 1 collaboration

Paula Alonso 1 collaboration

Alba Iglesias 1 collaboration

Pedro Casado 1 collaboration

David Martín-Oliva 1 collaboration

Pedro R Cutillas 1 collaboration

Javier González-Maeso 1 collaboration

Juan F López-Giménez 1 collaboration

Francisco Triana-Martínez 1 collaboration

Pilar Picallos-Rabina 1 collaboration

Sabela Da Silva-Álvarez 1 collaboration

Federico Pietrocola 1 collaboration

Susana Llanos 1 collaboration

Verónica Rodilla 1 collaboration

Enrica Soprano 1 collaboration

Pablo Pedrosa 1 collaboration

Alba Ferreirós 1 collaboration

Marta Barradas 1 collaboration

Fernanda Hernández-González 1 collaboration

Marta Lalinde 1 collaboration

Neus Prats 1 collaboration

Cristina Bernadó 1 collaboration

Patricia González 1 collaboration

María Gómez 1 collaboration

Maria P Ikonomopoulou 1 collaboration

Pablo J Fernández-Marcos 1 collaboration

Tomás García-Caballero 1 collaboration

Pablo Del Pino 1 collaboration

Joaquín Arribas 1 collaboration

Anxo Vidal 1 collaboration

Miguel González-Barcia 1 collaboration

Manuel Serrano 1 collaboration

Manuel Collado 1 collaboration

Antón L Martínez 1 collaboration

María J Varela 1 collaboration

Catarina Allegue 1 collaboration

Raquel Cruz 1 collaboration

Xavier Monroy 1 collaboration

Manuel Merlos 1 collaboration

Javier Burgueño 1 collaboration

Ángel Carracedo 1 collaboration

Breno A Soares 1 collaboration

Darío Martínez-Afani 1 collaboration

Williams Acevedo-Fuentes 1 collaboration

Gemma Navarro 1 collaboration

Iu Raïch 1 collaboration