M Scheffner

Affiliations

University of Konstanz, Department of Biology, Konstanz, Germany.

Publications (25)

The Length of a Ubiquitin Chain: A General Factor for Selective Recognition by Ubiquitin-Binding Proteins.

Angewandte Chemie (International ed. in English)

Avec: Joachim Lutz , Eva Höllmüller , Martin Scheffner , Andreas Marx , Florian Stengel

A ubiquitin variant-based affinity approach selectively identifies substrates of the ubiquitin ligase E6AP in complex with HPV-11 E6 or HPV-16 E6.

The Journal of biological chemistry

Avec: Felix A Ebner , Carolin Sailer , Daniela Eichbichler , Jasmin Jansen , Anna Sladewska-Marquardt , Florian Stengel , Martin Scheffner

Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.

EMBO reports

Avec: Julius Bogomolovas , Jennifer R Fleming , Barbara Franke , Bruno Manso , Bernd Simon , Alexander Gasch , Marija Markovic , Thomas Brunner , Ralph Knöll , Ju Chen , Siegfried Labeit , Martin Scheffner , Christine Peter , Olga Mayans

Biochemical and Structural Consequences of NEDD8 Acetylation.

Chembiochem : a European journal of chemical biology

Avec: Simon Maria Kienle , Tobias Schneider , Christine Bernecker , Janina Bracker , Andreas Marx , Michael Kovermann , Martin Scheffner , Katrin Stuber

Generation and Characterization of Site-Specifically Mono-Ubiquitylated p53.

Chembiochem : a European journal of chemical biology

Avec: Alexandra Julier , Vanessa Radtke , Andreas Marx , Martin Scheffner

Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function.

Nature communications

Avec: Simon Maria Kienle , Tobias Schneider , Katrin Stuber , Christoph Globisch , Jasmin Jansen , Florian Stengel , Christine Peter , Andreas Marx , Michael Kovermann , Martin Scheffner

Chemoproteomic discovery of a human RNA ligase.

Nature communications

Avec: Yizhi Yuan , Florian M Stumpf , Lisa A Schlor , Olivia P Schmidt , Philip Saumer , Luisa B Huber , Matthias Frese , Eva Höllmüller , Martin Scheffner , Florian Stengel , Kay Diederichs , Andreas Marx

Machine Learning Driven Analysis of Large Scale Simulations Reveals Conformational Characteristics of Ubiquitin Chains.

Journal of chemical theory and computation

Avec: Andrej Berg , Leon Franke , Martin Scheffner , Christine Peter

Study of adhesion and migration dynamics in ubiquitin E3A ligase (UBE3A)-silenced SYSH5Y neuroblastoma cells by micro-structured surfaces.

Nanotechnology

Avec: R Mezzena , C Masciullo , S Antonini , F Cremisi , M Scheffner , M Cecchini , I Tonazzini

FAT10 and NUB1L cooperate to activate the 26S proteasome.

Life science alliance

Avec: Florian Brockmann , Nicola Catone , Christine Wünsch , Fabian Offensperger , Martin Scheffner , Gunter Schmidtke , Annette Aichem

Thermostable protein-stabilized gold nanoclusters as a peroxidase mimic.

Nanoscale advances

Avec: Özlem Akyüz , Maite Mißun , Rose Rosenberg , Martin Scheffner , Andreas Marx , Helmut Cölfen

Artificially Linked Ubiquitin Dimers Characterised Structurally and Dynamically by NMR Spectroscopy.

Chembiochem : a European journal of chemical biology

Avec: Xiaohui Zhao , Maite Mißun , Tobias Schneider , Franziska Müller , Joachim Lutz , Martin Scheffner , Andreas Marx , Michael Kovermann

Assembly of branched ubiquitin oligomers by click chemistry.

Chemical communications (Cambridge, England)

Avec: Xiaohui Zhao , Martin Scheffner , Andreas Marx

On Biomineralization: Enzymes Switch on Mesocrystal Assembly.

ACS central science

Avec: Ashit Rao , Teresa Roncal-Herrero , Elina Schmid , Markus Drechsler , Martin Scheffner , Denis Gebauer , Roland Kröger , Helmut Cölfen

Structural and functional consequences of NEDD8 phosphorylation.

Nature communications

Avec: Katrin Stuber , Tobias Schneider , Jill Werner , Michael Kovermann , Andreas Marx , Martin Scheffner

Interactome of Site-Specifically Acetylated Linker Histone H1.

Journal of proteome research

Avec: Eva Höllmüller , Katharina Greiner , Simon M Kienle , Martin Scheffner , Andreas Marx , Florian Stengel

MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression.

Cell reports

Avec: Celeste Giansanti , Valentina Manzini , Antje Dickmanns , Achim Dickmanns , Maria Dilia Palumbieri , Andrea Sanchi , Simon Maria Kienle , Sonja Rieth , Martin Scheffner , Massimo Lopes , Matthias Dobbelstein

Interactome of intact chromatosome variants with site-specifically ubiquitylated and acetylated linker histone H1.2.

Nucleic acids research

Avec: Philip Saumer , Martin Scheffner , Andreas Marx , Florian Stengel

Effects of the antifungal agent ciclopirox in HPV-positive cancer cells: Repression of viral E6/E7 oncogene expression and induction of senescence and apoptosis.

International journal of cancer

Avec: Julia A Braun , Anja L Herrmann , Johanna I Blase , Kristin Frensemeier , Julia Bulkescher , Martin Scheffner , Bruno Galy , Karin Hoppe-Seyler , Felix Hoppe-Seyler

Formation of the Alarmones Diadenosine Triphosphate and Tetraphosphate by Ubiquitin- and Ubiquitin-like-Activating Enzymes.

Cell chemical biology

Avec: Kathrin H Götz , Martin Mex , Katrin Stuber , Fabian Offensperger , Martin Scheffner , Andreas Marx

Fluorescently Labelled ATP Analogues for Direct Monitoring of Ubiquitin Activation.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Daniel Hammler , Katrin Stuber , Fabian Offensperger , Martin Scheffner , Andreas Zumbusch , Andreas Marx

Site-specific ubiquitylation acts as a regulator of linker histone H1.

Nature communications

Avec: Eva Höllmüller , Simon Geigges , Marie L Niedermeier , Kai-Michael Kammer , Simon M Kienle , Daniel Rösner , Martin Scheffner , Andreas Marx , Florian Stengel

Identification of Small-Molecule Activators of the Ubiquitin Ligase E6AP/UBE3A and Angelman Syndrome-Derived E6AP/UBE3A Variants.

Cell chemical biology

Avec: Fabian Offensperger , Franziska Müller , Jasmin Jansen , Daniel Hammler , Kathrin H Götz , Andreas Marx , Carissa L Sirois , Stormy J Chamberlain , Florian Stengel , Martin Scheffner

Chemical proteomic profiling reveals protein interactors of the alarmones diadenosine triphosphate and tetraphosphate.

Nature communications

Avec: Lena Krüger , Christoph J Albrecht , Hannah K Schammann , Florian M Stumpf , Marie L Niedermeier , Yizhi Yuan , Katrin Stuber , Josua Wimmer , Florian Stengel , Martin Scheffner , Andreas Marx

Cobalamins function as allosteric activators of an Angelman syndrome-associated UBE3A/E6AP variant.

Chembiochem : a European journal of chemical biology

Avec: Franziska Müller , Jasmin Jansen , Fabian Offensperger , Daniela Eichbichler , Florian Stengel , Martin Scheffner

Réseau de co-auteurs

Martin Scheffner 24 collaborations

Andreas Marx 16 collaborations

Florian Stengel 10 collaborations

Katrin Stuber 6 collaborations

Fabian Offensperger 5 collaborations

Eva Höllmüller 4 collaborations

Jasmin Jansen 4 collaborations

Tobias Schneider 4 collaborations

Michael Kovermann 4 collaborations

Christine Peter 3 collaborations

Simon Maria Kienle 3 collaborations

Franziska Müller 3 collaborations

Joachim Lutz 2 collaborations

Daniela Eichbichler 2 collaborations

Yizhi Yuan 2 collaborations

Florian M Stumpf 2 collaborations

Philip Saumer 2 collaborations

Maite Mißun 2 collaborations

Helmut Cölfen 2 collaborations

Xiaohui Zhao 2 collaborations

Simon M Kienle 2 collaborations

Kathrin H Götz 2 collaborations

Daniel Hammler 2 collaborations

Marie L Niedermeier 2 collaborations

Felix A Ebner 1 collaboration

Carolin Sailer 1 collaboration

Anna Sladewska-Marquardt 1 collaboration

Julius Bogomolovas 1 collaboration

Jennifer R Fleming 1 collaboration

Barbara Franke 1 collaboration

Bruno Manso 1 collaboration

Bernd Simon 1 collaboration

Alexander Gasch 1 collaboration

Marija Markovic 1 collaboration

Thomas Brunner 1 collaboration

Ralph Knöll 1 collaboration

Ju Chen 1 collaboration

Siegfried Labeit 1 collaboration

Olga Mayans 1 collaboration

Christine Bernecker 1 collaboration

Janina Bracker 1 collaboration

Alexandra Julier 1 collaboration

Vanessa Radtke 1 collaboration

Christoph Globisch 1 collaboration

Lisa A Schlor 1 collaboration

Olivia P Schmidt 1 collaboration

Luisa B Huber 1 collaboration

Matthias Frese 1 collaboration

Kay Diederichs 1 collaboration

Andrej Berg 1 collaboration

Leon Franke 1 collaboration

R Mezzena 1 collaboration

C Masciullo 1 collaboration

S Antonini 1 collaboration

F Cremisi 1 collaboration

M Cecchini 1 collaboration

I Tonazzini 1 collaboration

Florian Brockmann 1 collaboration

Nicola Catone 1 collaboration

Christine Wünsch 1 collaboration

Gunter Schmidtke 1 collaboration

Annette Aichem 1 collaboration

Özlem Akyüz 1 collaboration

Rose Rosenberg 1 collaboration

Ashit Rao 1 collaboration

Teresa Roncal-Herrero 1 collaboration

Elina Schmid 1 collaboration

Markus Drechsler 1 collaboration

Denis Gebauer 1 collaboration

Roland Kröger 1 collaboration

Jill Werner 1 collaboration

Katharina Greiner 1 collaboration

Celeste Giansanti 1 collaboration

Valentina Manzini 1 collaboration

Antje Dickmanns 1 collaboration

Achim Dickmanns 1 collaboration

Maria Dilia Palumbieri 1 collaboration

Andrea Sanchi 1 collaboration

Sonja Rieth 1 collaboration

Massimo Lopes 1 collaboration

Matthias Dobbelstein 1 collaboration

Julia A Braun 1 collaboration

Anja L Herrmann 1 collaboration

Johanna I Blase 1 collaboration

Kristin Frensemeier 1 collaboration

Julia Bulkescher 1 collaboration

Bruno Galy 1 collaboration

Karin Hoppe-Seyler 1 collaboration

Felix Hoppe-Seyler 1 collaboration

Martin Mex 1 collaboration

Andreas Zumbusch 1 collaboration

Simon Geigges 1 collaboration

Kai-Michael Kammer 1 collaboration

Daniel Rösner 1 collaboration

Carissa L Sirois 1 collaboration

Stormy J Chamberlain 1 collaboration

Lena Krüger 1 collaboration

Christoph J Albrecht 1 collaboration

Hannah K Schammann 1 collaboration

Josua Wimmer 1 collaboration