Magnus Essand

Affiliations

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85 Uppsala, Sweden.

Publications (24)

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy.

Cell stem cell

Avec: Matko Čančer , Sonja Hutter , Karl O Holmberg , Gabriela Rosén , Anders Sundström , Jignesh Tailor , Tobias Bergström , Alexandra Garancher , Magnus Essand , Robert J Wechsler-Reya , Anna Falk , Holger Weishaupt , Fredrik J Swartling

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain.

Journal of neuroinflammation

Avec: Jinar Rostami , Grammatiki Fotaki , Julien Sirois , Ropafadzo Mzezewa , Joakim Bergström , Magnus Essand , Luke Healy , Anna Erlandsson

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma.

Nature communications

Avec: Luuk van Hooren , Alessandra Vaccaro , Mohanraj Ramachandran , Konstantinos Vazaios , Sylwia Libard , Tiarne van de Walle , Maria Georganaki , Hua Huang , Ilkka Pietilä , Joey Lau , Maria H Ulvmar , Mikael C I Karlsson , Maria Zetterling , Sara M Mangsbo , Asgeir S Jakola , Thomas Olsson Bontell , Anja Smits , Magnus Essand , Anna Dimberg

Perivascular Macrophages Regulate Blood Flow Following Tissue Damage.

Circulation research

Avec: Evelina Vågesjö , Kristel Parv , David Ahl , Cédric Seignez , Carmen Herrera Hidalgo , Antoine Giraud , Catarina Leite , Olle Korsgren , Håkan Wallén , Greta Juusola , Harri H Hakovirta , Helene Rundqvist , Magnus Essand , Lena Holm , Randall S Johnson , Charlotte Thålin , Petra Korpisalo , Gustaf Christoffersson , Mia Phillipson

CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease

Molecular therapy. Nucleic acids

Avec: Evangelos Konstantinidis , Agnieszka Molisak , Florian Perrin , Linn Streubel-Gallasch , Sarah Fayad , Daniel Y Kim , Karl Petri , Martin J Aryee , Ximena Aguilar , Bence György , Vilmantas Giedraitis , J Keith Joung , Vikram Pattanayak , Magnus Essand , Anna Erlandsson , Oksana Berezovska , Martin Ingelsson

CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers.

Nature biomedical engineering

Avec: Chuan Jin , Jing Ma , Mohanraj Ramachandran , Di Yu , Magnus Essand

IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma.

Molecular therapy oncolytics

Avec: Miika Martikainen , Mohanraj Ramachandran , Roberta Lugano , Jing Ma , Minttu-Maria Martikainen , Anna Dimberg , Di Yu , Andres Merits , Magnus Essand

Ixovex-1, a novel oncolytic E1B-mutated adenovirus.

Cancer gene therapy

Avec: Mohiemen Anwar , Maja-Louise Arendt , Mohanraj Ramachandran , Anette Carlsson , Magnus Essand , Göran Akusjärvi , Ghasan Alusi , Daniel Öberg

Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer.

Frontiers in immunology

Avec: Alessandra Vaccaro , Tiarne van de Walle , Mohanraj Ramachandran , Magnus Essand , Anna Dimberg

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy.

Oncoimmunology

Avec: Maria Georganaki , Mohanraj Ramachandran , Sander Tuit , Nicolás Gonzalo Núñez , Alexandros Karampatzakis , Grammatiki Fotaki , Luuk van Hooren , Hua Huang , Roberta Lugano , Thomas Ulas , Aura Kaunisto , Eric C Holland , Peter Ellmark , Sara M Mangsbo , Joachim Schultze , Magnus Essand , Sonia Tugues , Anna Dimberg

Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer.

Cell death & disease

Avec: Jing Ma , Mohanraj Ramachandran , Chuan Jin , Clara Quijano-Rubio , Miika Martikainen , Di Yu , Magnus Essand

Virus-Based Immunotherapy of Glioblastoma.

Cancers

Avec: Miika Martikainen , Magnus Essand

LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients.

The Journal of pathology

Avec: Yuan Xie , Anders Sundström , Naga P Maturi , E-Jean Tan , Voichita D Marinescu , Malin Jarvius , Malin Tirfing , Chuan Jin , Lei Chen , Magnus Essand , Fredrik J Swartling , Sven Nelander , Yiwen Jiang , Lene Uhrbom

Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus.

Nanomedicine : nanotechnology, biology, and medicine

Avec: Alessandra Iscaro , Christian Jones , Neil Forbes , Amina Mughal , Faith Nutter Howard , Haider Al Janabi , Secil Demiral , Yvonne Perrie , Magnus Essand , Aleksandra Weglarz , Luis J Cruz , Claire E Lewis , Munitta Muthana

ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression.

Frontiers in immunology

Avec: Mahmoud Darweesh , Shady Younis , Zamaneh Hajikhezri , Arwa Ali , Chuan Jin , Tanel Punga , Soham Gupta , Magnus Essand , Leif Andersson , Göran Akusjärvi

Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy.

Cancer imaging : the official publication of the International Cancer Imaging Society

Avec: Therese Sjöholm , Alexander Korenyushkin , Gustav Gammelgård , Tina Sarén , Tanja Lövgren , Angelica Loskog , Magnus Essand , Joel Kullberg , Gunilla Enblad , Håkan Ahlström

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment.

Haematologica

Avec: Barbara Depreter , Karin E Weening , Karl Vandepoele , Magnus Essand , Barbara De Moerloose , Maria Themeli , Jacqueline Cloos , Diana Hanekamp , Ine Moors , Inge D'hont , Barbara Denys , Anne Uyttebroeck , An Van Damme , Laurence Dedeken , Sylvia Snauwaert , Glenn Goetgeluk , Stijn De Munter , Tessa Kerre , Bart Vandekerckhove , Tim Lammens , Jan Philippé

Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy.

Nanomaterials (Basel, Switzerland)

Avec: Siyuan Deng , Alessandra Iscaro , Giorgia Zambito , Yimin Mijiti , Marco Minicucci , Magnus Essand , Clemens Lowik , Munitta Muthana , Roberta Censi , Laura Mezzanotte , Piera Di Martino

Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma.

Frontiers in immunology

Avec: Tiarne van de Walle , Alessandra Vaccaro , Mohanraj Ramachandran , Ilkka Pietilä , Magnus Essand , Anna Dimberg

Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-tumor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response.

Oncoimmunology

Avec: Chuan Jin , Arwa Ali , Alexandros Iskantar , Grammatiki Fotaki , Hai Wang , Magnus Essand , Alex Karlsson-Parra , Di Yu

Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma.

Cancer cell

Avec: Mohanraj Ramachandran , Alessandra Vaccaro , Tiarne van de Walle , Maria Georganaki , Roberta Lugano , Kalyani Vemuri , Despoina Kourougkiaouri , Konstantinos Vazaios , Marie Hedlund , Georgia Tsaridou , Lene Uhrbom , Ilkka Pietilä , Miika Martikainen , Luuk van Hooren , Thomas Olsson Bontell , Asgeir S Jakola , Di Yu , Bengt Westermark , Magnus Essand , Anna Dimberg

CD4

Nature

Avec: Bastian Kruse , Anthony C Buzzai , Naveen Shridhar , Andreas D Braun , Susan Gellert , Kristin Knauth , Joanna Pozniak , Johannes Peters , Paulina Dittmann , Miriam Mengoni , Tetje Cornelia van der Sluis , Simon Höhn , Asier Antoranz , Anna Krone , Yan Fu , Di Yu , Magnus Essand , Robert Geffers , Dimitrios Mougiakakos , Sascha Kahlfuß , Hamid Kashkar , Evelyn Gaffal , Francesca M Bosisio , Oliver Bechter , Florian Rambow , Jean-Christophe Marine , Wolfgang Kastenmüller , Andreas J Müller , Thomas Tüting

Complementarity-determining region clustering may cause CAR-T cell dysfunction.

Nature communications

Avec: Tina Sarén , Giulia Saronio , Paula Marti Torrell , Xu Zhu , Josefin Thelander , Yasmin Andersson , Camilla Hofström , Marika Nestor , Anna Dimberg , Helena Persson , Mohanraj Ramachandran , Di Yu , Magnus Essand

Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Tina Sarén , Mohanraj Ramachandran , Gustav Gammelgård , Tanja Lövgren , Claudio Mirabello , Åsa K Björklund , Kristina Wikström , Jamileh Hashemi , Eva Freyhult , Håkan Ahlström , Rose-Marie Amini , Hans Hagberg , Angelica Loskog , Gunilla Enblad , Magnus Essand

Réseau de co-auteurs

Mohanraj Ramachandran 11 collaborations

Anna Dimberg 7 collaborations

Di Yu 7 collaborations

Chuan Jin 5 collaborations

Alessandra Vaccaro 4 collaborations

Tiarne van de Walle 4 collaborations

Miika Martikainen 4 collaborations

Grammatiki Fotaki 3 collaborations

Luuk van Hooren 3 collaborations

Maria Georganaki 3 collaborations

Ilkka Pietilä 3 collaborations

Jing Ma 3 collaborations

Roberta Lugano 3 collaborations

Tina Sarén 3 collaborations

Anders Sundström 2 collaborations

Fredrik J Swartling 2 collaborations

Anna Erlandsson 2 collaborations

Konstantinos Vazaios 2 collaborations

Hua Huang 2 collaborations

Sara M Mangsbo 2 collaborations

Asgeir S Jakola 2 collaborations

Thomas Olsson Bontell 2 collaborations

Göran Akusjärvi 2 collaborations

Lene Uhrbom 2 collaborations

Alessandra Iscaro 2 collaborations

Munitta Muthana 2 collaborations

Arwa Ali 2 collaborations

Gustav Gammelgård 2 collaborations

Tanja Lövgren 2 collaborations

Angelica Loskog 2 collaborations

Gunilla Enblad 2 collaborations

Håkan Ahlström 2 collaborations

Matko Čančer 1 collaboration

Sonja Hutter 1 collaboration

Karl O Holmberg 1 collaboration

Gabriela Rosén 1 collaboration

Jignesh Tailor 1 collaboration

Tobias Bergström 1 collaboration

Alexandra Garancher 1 collaboration

Robert J Wechsler-Reya 1 collaboration

Anna Falk 1 collaboration

Holger Weishaupt 1 collaboration

Jinar Rostami 1 collaboration

Julien Sirois 1 collaboration

Ropafadzo Mzezewa 1 collaboration

Joakim Bergström 1 collaboration

Luke Healy 1 collaboration

Sylwia Libard 1 collaboration

Joey Lau 1 collaboration

Maria H Ulvmar 1 collaboration

Mikael C I Karlsson 1 collaboration

Maria Zetterling 1 collaboration

Anja Smits 1 collaboration

Evelina Vågesjö 1 collaboration

Kristel Parv 1 collaboration

David Ahl 1 collaboration

Cédric Seignez 1 collaboration

Carmen Herrera Hidalgo 1 collaboration

Antoine Giraud 1 collaboration

Catarina Leite 1 collaboration

Olle Korsgren 1 collaboration

Håkan Wallén 1 collaboration

Greta Juusola 1 collaboration

Harri H Hakovirta 1 collaboration

Helene Rundqvist 1 collaboration

Lena Holm 1 collaboration

Randall S Johnson 1 collaboration

Charlotte Thålin 1 collaboration

Petra Korpisalo 1 collaboration

Gustaf Christoffersson 1 collaboration

Mia Phillipson 1 collaboration

Evangelos Konstantinidis 1 collaboration

Agnieszka Molisak 1 collaboration

Florian Perrin 1 collaboration

Linn Streubel-Gallasch 1 collaboration

Sarah Fayad 1 collaboration

Daniel Y Kim 1 collaboration

Karl Petri 1 collaboration

Martin J Aryee 1 collaboration

Ximena Aguilar 1 collaboration

Bence György 1 collaboration

Vilmantas Giedraitis 1 collaboration

J Keith Joung 1 collaboration

Vikram Pattanayak 1 collaboration

Oksana Berezovska 1 collaboration

Martin Ingelsson 1 collaboration

Minttu-Maria Martikainen 1 collaboration

Andres Merits 1 collaboration

Mohiemen Anwar 1 collaboration

Maja-Louise Arendt 1 collaboration

Anette Carlsson 1 collaboration

Ghasan Alusi 1 collaboration

Daniel Öberg 1 collaboration

Sander Tuit 1 collaboration

Nicolás Gonzalo Núñez 1 collaboration

Alexandros Karampatzakis 1 collaboration

Thomas Ulas 1 collaboration

Aura Kaunisto 1 collaboration

Eric C Holland 1 collaboration

Peter Ellmark 1 collaboration

Joachim Schultze 1 collaboration

Sonia Tugues 1 collaboration

Clara Quijano-Rubio 1 collaboration

Yuan Xie 1 collaboration

Naga P Maturi 1 collaboration

E-Jean Tan 1 collaboration

Voichita D Marinescu 1 collaboration

Malin Jarvius 1 collaboration

Malin Tirfing 1 collaboration

Lei Chen 1 collaboration

Sven Nelander 1 collaboration

Yiwen Jiang 1 collaboration

Christian Jones 1 collaboration

Neil Forbes 1 collaboration

Amina Mughal 1 collaboration

Faith Nutter Howard 1 collaboration

Haider Al Janabi 1 collaboration

Secil Demiral 1 collaboration

Yvonne Perrie 1 collaboration

Aleksandra Weglarz 1 collaboration

Luis J Cruz 1 collaboration

Claire E Lewis 1 collaboration

Mahmoud Darweesh 1 collaboration

Shady Younis 1 collaboration

Zamaneh Hajikhezri 1 collaboration

Tanel Punga 1 collaboration

Soham Gupta 1 collaboration

Leif Andersson 1 collaboration

Therese Sjöholm 1 collaboration

Alexander Korenyushkin 1 collaboration

Joel Kullberg 1 collaboration

Barbara Depreter 1 collaboration

Karin E Weening 1 collaboration

Karl Vandepoele 1 collaboration

Barbara De Moerloose 1 collaboration

Maria Themeli 1 collaboration

Jacqueline Cloos 1 collaboration

Diana Hanekamp 1 collaboration

Ine Moors 1 collaboration

Inge D'hont 1 collaboration

Barbara Denys 1 collaboration

Anne Uyttebroeck 1 collaboration

An Van Damme 1 collaboration

Laurence Dedeken 1 collaboration

Sylvia Snauwaert 1 collaboration

Glenn Goetgeluk 1 collaboration

Stijn De Munter 1 collaboration

Tessa Kerre 1 collaboration

Bart Vandekerckhove 1 collaboration

Tim Lammens 1 collaboration

Jan Philippé 1 collaboration

Siyuan Deng 1 collaboration

Giorgia Zambito 1 collaboration

Yimin Mijiti 1 collaboration

Marco Minicucci 1 collaboration

Clemens Lowik 1 collaboration

Roberta Censi 1 collaboration

Laura Mezzanotte 1 collaboration

Piera Di Martino 1 collaboration

Alexandros Iskantar 1 collaboration

Hai Wang 1 collaboration

Alex Karlsson-Parra 1 collaboration

Kalyani Vemuri 1 collaboration

Despoina Kourougkiaouri 1 collaboration

Marie Hedlund 1 collaboration

Georgia Tsaridou 1 collaboration

Bengt Westermark 1 collaboration

Bastian Kruse 1 collaboration

Anthony C Buzzai 1 collaboration

Naveen Shridhar 1 collaboration

Andreas D Braun 1 collaboration

Susan Gellert 1 collaboration

Kristin Knauth 1 collaboration

Joanna Pozniak 1 collaboration

Johannes Peters 1 collaboration

Paulina Dittmann 1 collaboration

Miriam Mengoni 1 collaboration

Tetje Cornelia van der Sluis 1 collaboration

Simon Höhn 1 collaboration

Asier Antoranz 1 collaboration

Anna Krone 1 collaboration

Yan Fu 1 collaboration

Robert Geffers 1 collaboration

Dimitrios Mougiakakos 1 collaboration

Sascha Kahlfuß 1 collaboration

Hamid Kashkar 1 collaboration

Evelyn Gaffal 1 collaboration

Francesca M Bosisio 1 collaboration

Oliver Bechter 1 collaboration

Florian Rambow 1 collaboration

Jean-Christophe Marine 1 collaboration

Wolfgang Kastenmüller 1 collaboration

Andreas J Müller 1 collaboration

Thomas Tüting 1 collaboration

Giulia Saronio 1 collaboration

Paula Marti Torrell 1 collaboration

Xu Zhu 1 collaboration

Josefin Thelander 1 collaboration

Yasmin Andersson 1 collaboration

Camilla Hofström 1 collaboration

Marika Nestor 1 collaboration

Helena Persson 1 collaboration

Claudio Mirabello 1 collaboration

Åsa K Björklund 1 collaboration

Kristina Wikström 1 collaboration

Jamileh Hashemi 1 collaboration

Eva Freyhult 1 collaboration

Rose-Marie Amini 1 collaboration

Hans Hagberg 1 collaboration