Dimitrios Mougiakakos

Affiliations
  • Department of Internal Medicine V, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany.

Publications (76)

B Cell Speed and B-FDC Contacts in Germinal Centers Determine Plasma Cell Output via Swiprosin-1/EFhd2.

Cell reports
Avec: Dorothea Reimer , Michael Meyer-Hermann , Asylkhan Rakhymzhan , Tobit Steinmetz , Philipp Tripal , Jana Thomas , Martin Boettcher , Dimitrios Mougiakakos , Sebastian R Schulz , Sophia Urbanczyk , Anja E Hauser , Raluca A Niesner , Dirk Mielenz

PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass.

Scientific reports
Avec: Dorothea I H Müller , Cornelia Stoll , Katrin Palumbo-Zerr , Christina Böhm , Brenda Krishnacoumar , Natacha Ipseiz , Jule Taubmann , Max Zimmermann , Martin Böttcher , Dimitrios Mougiakakos , Jan Tuckermann , Farida Djouad , Georg Schett , Carina Scholtysek , Gerhard Krönke

Rapid and Efficient Gene Editing for Direct Transplantation of Naive Murine Cas9

Frontiers in immunology
Avec: Snigdha Majumder , Isabelle Jugovic , Domenica Saul , Luisa Bell , Nadine Hundhausen , Rishav Seal , Andreas Beilhack , Andreas Rosenwald , Dimitrios Mougiakakos , Friederike Berberich-Siebelt

CAR-HEMATOTOX: a model for CAR T-cell-related hematologic toxicity in relapsed/refractory large B-cell lymphoma.

Blood
Avec: Kai Rejeski , Ariel Perez , Pierre Sesques , Eva Hoster , Carolina Berger , Liv Jentzsch , Dimitrios Mougiakakos , Lisa Frölich , Josephine Ackermann , Veit Bücklein , Viktoria Blumenberg , Christian Schmidt , Laurent Jallades , Boris Fehse , Christoph Faul , Philipp Karschnia , Oliver Weigert , Martin Dreyling , Frederick L Locke , Michael von Bergwelt-Baildon , Andreas Mackensen , Wolfgang Bethge , Francis Ayuk , Emmanuel Bachy , Gilles Salles , Michael D Jain , Marion Subklewe

Parameters of body composition do not predict survival in patients with multiple myeloma undergoing autologous stem cell transplantation.

Leukemia & lymphoma
Avec: Felix Barajas Ordonez , Denise Wolleschak , Yannic Zeller , Mattes Hinnerichs , Pablo Rodríguez-Feria , Anar Aghayev , Martin Mikusko , Jan Borggrefe , Dimitrios Mougiakakos , Alexey Surov

Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.

Nature
Avec: Jean-Philippe Auger , Max Zimmermann , Maria Faas , Ulrich Stifel , David Chambers , Brenda Krishnacoumar , R Verena Taudte , Charlotte Grund , Gitta Erdmann , Carina Scholtysek , Stefan Uderhardt , Oumaima Ben Brahim , Mónica Pascual Maté , Cornelia Stoll , Martin Böttcher , Katrin Palumbo-Zerr , Matthew S J Mangan , Maria Dzamukova , Markus Kieler , Melanie Hofmann , Stephan Blüml , Gernot Schabbauer , Dimitrios Mougiakakos , Uwe Sonnewald , Fabian Hartmann , David Simon , Arnd Kleyer , Anika Grüneboom , Susetta Finotto , Eicke Latz , Jörg Hofmann , Georg Schett , Jan Tuckermann , Gerhard Krönke

Treatment of concomitant myasthenia gravis and Lambert-Eaton myasthenic syndrome with autologous CD19-targeted CAR T cells.

Neuron
Avec: Jeremias Motte , Melissa Sgodzai , Christiane Schneider-Gold , Nina Steckel , Thomas Mika , Tobias Hegelmaier , Dominic Borie , Aiden Haghikia , Dimitrios Mougiakakos , Roland Schroers , Ralf Gold

Feasibility, Safety, and Preliminary Efficacy of Very Low-Volume Interval Training in Advanced Cancer Patients.

Medicine and science in sports and exercise
Avec: Dejan Reljic , Hans J Herrmann , Benedikt Jakobs , Walburga Dieterich , Dimitrios Mougiakakos , Markus F Neurath , Yurdagül Zopf

GLA/DRST real-world outcome analysis of CAR T-cell therapies for large B-cell lymphoma in Germany.

Blood
Avec: Wolfgang A Bethge , Peter Martus , Michael Schmitt , Udo Holtick , Marion Subklewe , Bastian von Tresckow , Francis Ayuk , Eva Marie Wagner-Drouet , Gerald G Wulf , Reinhard Marks , Olaf Penack , Ulf Schnetzke , Christian Koenecke , Malte von Bonin , Matthias Stelljes , Bertram Glass , Claudia D Baldus , Vladan Vucinic , Dimitrios Mougiakakos , Max Topp , Matthias A Fante , Roland Schroers , Lale Bayir , Peter Borchmann , Veit Buecklein , Justin Hasenkamp , Christine Hanoun , Simone Thomas , Dietrich W Beelen , Claudia Lengerke , Nicolaus Kroeger , Peter Dreger

Role of CAR T Cell Metabolism for Therapeutic Efficacy.

Cancers
Avec: Judit Rial Saborido , Simon Völkl , Michael Aigner , Andreas Mackensen , Dimitrios Mougiakakos

CAR T-cell therapy in autoimmune diseases.

Lancet (London, England)
Avec: Georg Schett , Andreas Mackensen , Dimitrios Mougiakakos

Selective CAR-T cell mediated B cell depletion suppresses interferon signature in SLE.

JCI insight
Avec: Artur Wilhelm , David Chambers , Fabian Müller , Aline Bozec , Ricardo Grieshaber-Bouyer , Thomas Winkler , Dimitrios Mougiakakos , Andreas Mackensen , Georg Schett , Gerhard Krönke

Hypogammaglobulinemia and anti-CD20 therapy-induced acute thrombocytopenia: perhaps more than a coincidence?

Oncology research and treatment
Avec: Tobias Ronny Haage , Vanja Zeremski , Mirjeta Berisha , Dimitrios Mougiakakos

Palmitoylated Proteins on AML-Derived Extracellular Vesicles Promote Myeloid-Derived Suppressor Cell Differentiation via TLR2/Akt/mTOR Signaling.

Cancer research
Avec: Sehmus Tohumeken , Rebecca Baur , Martin Böttcher , Andrej Stoll , Romy Loschinski , Konstantinos Panagiotidis , Martina Braun , Domenica Saul , Simon Völkl , Andreas S Baur , Heiko Bruns , Andreas Mackensen , Regina Jitschin , Dimitrios Mougiakakos

Energy metabolism is co-determined by genetic variants in chronic lymphocytic leukemia and influences drug sensitivity.

Haematologica
Avec: Junyan Lu , Martin Böttcher , Tatjana Walther , Dimitrios Mougiakakos , Thorsten Zenz , Wolfgang Huber

T-Cell Metabolism in Graft

Frontiers in immunology
Avec: Franziska Karl , Michael Hudecek , Friederike Berberich-Siebelt , Andreas Mackensen , Dimitrios Mougiakakos

Linking Immunoevasion and Metabolic Reprogramming in B-Cell-Derived Lymphomas.

Frontiers in oncology
Avec: Martin Böttcher , Rebecca Baur , Andrej Stoll , Andreas Mackensen , Dimitrios Mougiakakos

Multi-omics reveals clinically relevant proliferative drive associated with mTOR-MYC-OXPHOS activity in chronic lymphocytic leukemia.

Nature cancer
Avec: Junyan Lu , Ester Cannizzaro , Fabienne Meier-Abt , Sebastian Scheinost , Peter-Martin Bruch , Holly Ar Giles , Almut Lütge , Jennifer Hüllein , Lena Wagner , Brian Giacopelli , Ferran Nadeu , Julio Delgado , Elías Campo , Maurizio Mangolini , Ingo Ringshausen , Martin Böttcher , Dimitrios Mougiakakos , Andrea Jacobs , Bernd Bodenmiller , Sascha Dietrich , Christopher C Oakes , Thorsten Zenz , Wolfgang Huber

Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas.

Blood advances
Avec: Nora Liebers , Johannes Duell , Donnacha Fitzgerald , Andrea Kerkhoff , Daniel Noerenberg , Eva Kaebisch , Fabian Acker , Stephan Fuhrmann , Corinna Leng , Manfred Welslau , Jens Chemnitz , Jan-Moritz Middeke , Thomas Weber , Udo Holtick , Ralf Trappe , Roald Pfannes , Ruediger Liersch , Christian Spoer , Stefan Fuxius , Niklas Gebauer , Léandra Caillé , Thomas Geer , Christian Koenecke , Ulrich Keller , Rainer Claus , Dimitrios Mougiakakos , Stephanie Mayer , Andreas Huettmann , Christiane Pott , Arne Trummer , Gerald Wulf , Uta Brunnberg , Lars Bullinger , Georg Hess , Carsten Mueller-Tidow , Bertram Glass , Georg Lenz , Peter Dreger , Sascha Dietrich

β

Immunity
Avec: Daniel Hofbauer , Dimitrios Mougiakakos , Luca Broggini , Mario Zaiss , Maike Büttner-Herold , Christian Bach , Bernd Spriewald , Frank Neumann , Savita Bisht , Jens Nolting , Robert Zeiser , Shaima'a Hamarsheh , Martin Eberhardt , Julio Vera , Cristina Visentin , Chiara Maria Giulia De Luca , Fabio Moda , Stefan Haskamp , Cindy Flamann , Martin Böttcher , Katrin Bitterer , Simon Völkl , Andreas Mackensen , Stefano Ricagno , Heiko Bruns

Sarcopenia does not predict outcome in patients with CNS lymphoma undergoing systemic therapy.

Oncology letters
Avec: Vincenzo Ferraro , Maximilian Thormann , Mattes Hinnerichs , Maciej Pech , Denise Wolleschak , Dimitrios Mougiakakos , Andreas Wienke , Alexandra Strobel , Vanja Zeremski , Alexey Surov , Jazan Omari

Reset of Inflammatory Priming of Joint Tissue and Reduction of the Severity of Arthritis Flares by Bromodomain Inhibition.

Arthritis & rheumatology (Hoboken, N.J.)
Avec: Jasna Friščić , Christiane Reinwald , Martin Böttcher , Miranda Houtman , Maximilien Euler , Xi Chen , Kellie I Walker , Philipp Kirchner , Honglin Zhu , Benjamin Wirth , Daniela Weidner , René Krüger , Vladimir Trajkovic , Arif B Ekici , Kerstin Klein , Dimitrios Mougiakakos , Caroline Ospelt , Georg Schett , Markus H Hoffmann

A key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients.

Leukemia
Avec: Giorgia Massacci , Veronica Venafra , Sara Latini , Valeria Bica , Giusj Monia Pugliese , Simone Graziosi , Felix Klingelhuber , Natalie Krahmer , Thomas Fischer , Dimitrios Mougiakakos , Martin Boettcher , Livia Perfetto , Francesca Sacco

CD4

Nature
Avec: Bastian Kruse , Anthony C Buzzai , Naveen Shridhar , Andreas D Braun , Susan Gellert , Kristin Knauth , Joanna Pozniak , Johannes Peters , Paulina Dittmann , Miriam Mengoni , Tetje Cornelia van der Sluis , Simon Höhn , Asier Antoranz , Anna Krone , Yan Fu , Di Yu , Magnus Essand , Robert Geffers , Dimitrios Mougiakakos , Sascha Kahlfuß , Hamid Kashkar , Evelyn Gaffal , Francesca M Bosisio , Oliver Bechter , Florian Rambow , Jean-Christophe Marine , Wolfgang Kastenmüller , Andreas J Müller , Thomas Tüting

How ITD Insertion Sites Orchestrate the Biology and Disease of FLT3-ITD-Mutated Acute Myeloid Leukemia.

Cancers
Avec: Tobias R Haage , Burkhart Schraven , Dimitrios Mougiakakos , Thomas Fischer

AML consolidation therapy: timing matters.

Journal of cancer research and clinical oncology
Avec: Adrian-Manuel Reimann , Enrico Schalk , Felix Jost , Dimitrios Mougiakakos , Daniela Weber , Hartmut Döhner , Christian Récher , Pierre-Yves Dumas , Marc Ditzhaus , Thomas Fischer , Sebastian Sager

Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry.

Cell communication and signaling : CCS
Avec: Vikas Bhuria , Tobias Franz , Conny Baldauf , Martin Böttcher , Nicolas Chatain , Steffen Koschmieder , Tim H Brümmendorf , Dimitrios Mougiakakos , Burkhart Schraven , Sascha Kahlfuß , Thomas Fischer

Successful use of anti-CD19 CAR T cells in severe treatment-refractory stiff-person syndrome.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Simon Faissner , Jeremias Motte , Melissa Sgodzai , Christian Geis , Aiden Haghikia , Dimitrios Mougiakakos , Dominic Borie , Roland Schroers , Ralf Gold

N-glycosylation controls inflammatory licensing-triggered PD-L1 upregulation in human mesenchymal stromal cells.

Stem cells (Dayton, Ohio)
Avec: Vivien Strauch , Domenica Saul , Mirjeta Berisha , Andreas Mackensen , Dimitrios Mougiakakos , Regina Jitschin

PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis.

Cellular and molecular life sciences : CMLS
Avec: Ingo Ganzleben , Gui-Wei He , Claudia Günther , Elena-Sophie Prigge , Karsten Richter , Ralf J Rieker , Dimitrios Mougiakakos , Markus F Neurath , Christoph Becker

Selective PRMT5 Inhibitors Suppress Human CD8

Molecular cancer therapeutics
Avec: Carolin Dorothea Strobl , Stefanie Schaffer , Tabea Haug , Simon Völkl , Katrin Peter , Katrin Singer , Martin Böttcher , Dimitrios Mougiakakos , Andreas Mackensen , Michael Aigner

IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation.

Immunity
Avec: Maria Faas , Natacha Ipseiz , Jochen Ackermann , Stephan Culemann , Anika Grüneboom , Fenja Schröder , Tobias Rothe , Carina Scholtysek , Martin Eberhardt , Martin Böttcher , Philipp Kirchner , Cornelia Stoll , Arif Ekici , Maximilian Fuchs , Meik Kunz , Benno Weigmann , Stefan Wirtz , Roland Lang , Joerg Hofmann , Julio Vera , David Voehringer , Alessandro Michelucci , Dimitrios Mougiakakos , Stefan Uderhardt , Georg Schett , Gerhard Krönke

Metabolic reprogramming of osteoclasts represents a therapeutic target during the treatment of osteoporosis.

Scientific reports
Avec: Jule Taubmann , Brenda Krishnacoumar , Christina Böhm , Maria Faas , Dorothea I H Müller , Susanne Adam , Cornelia Stoll , Martin Böttcher , Dimitrios Mougiakakos , Uwe Sonnewald , Jörg Hofmann , Georg Schett , Gerhard Krönke , Carina Scholtysek

The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL.

Journal for immunotherapy of cancer
Avec: Kai Rejeski , Ariel Perez , Gloria Iacoboni , Olaf Penack , Veit Bücklein , Liv Jentzsch , Dimitrios Mougiakakos , Grace Johnson , Brian Arciola , Cecilia Carpio , Viktoria Blumenberg , Eva Hoster , Lars Bullinger , Frederick L Locke , Michael von Bergwelt-Baildon , Andreas Mackensen , Wolfgang Bethge , Pere Barba , Michael D Jain , Marion Subklewe

Mitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling the flux of the TCA cycle.

Cell reports
Avec: Sophia Urbanczyk , Olivier R Baris , Jörg Hofmann , R Verena Taudte , Naïg Guegen , Florian Golombek , Kathrin Castiglione , Xianyi Meng , Aline Bozec , Jana Thomas , Leonie Weckwerth , Dimitrios Mougiakakos , Sebastian R Schulz , Wolfgang Schuh , Ursula Schlötzer-Schrehardt , Tobit D Steinmetz , Susanne Brodesser , Rudolf J Wiesner , Dirk Mielenz

Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia.

Blood
Avec: Hardikkumar Jetani , Almudena Navarro-Bailón , Marius Maucher , Silke Frenz , Christina Verbruggen , Ana Yeguas , María Belén Vidriales , Marcos González , Judit Rial Saborido , Sabrina Kraus , Katrin Mestermann , Simone Thomas , Halvard Bonig , Maik Luu , Razieh Monjezi , Dimitrios Mougiakakos , Markus Sauer , Hermann Einsele , Michael Hudecek

B cell-targeting chimeric antigen receptor T cells as an emerging therapy in neuroimmunological diseases.

The Lancet. Neurology
Avec: Aiden Haghikia , Georg Schett , Dimitrios Mougiakakos

Synergistic lethality in chronic myeloid leukemia - targeting oxidative phosphorylation and unfolded protein response effectively complements tyrosine kinase inhibitor treatment.

BMC cancer
Avec: Lukas Häselbarth , Sara Gamali , Domenica Saul , Manuela Krumbholz , Romy Böttcher-Loschinski , Martin Böttcher , Deyu Zou , Markus Metzler , Axel Karow , Dimitrios Mougiakakos

Relevance of different prognostic scores in primary CNS lymphoma in the era of intensified treatment regimens: A retrospective, multicenter analysis of 174 patients.

European journal of haematology
Avec: Vanja Zeremski , Louisa Adolph , Sina Beer , Mirjeta Berisha , Benedikt Jacobs , Christoph Kahl , Christian Koenecke , Siegfried Kropf , Jens Panse , Judith Petersen , Martin Schmidt-Hieber , Jessica Schneider , Vladan Vucinic , Jeanette Walter , Oliver Weigert , Hanno M Witte , Dimitrios Mougiakakos

Oxidative DNA damage in reconstituting T cells is associated with relapse and inferior survival after allo-SCT.

Blood
Avec: F Karl , C Liang , R Böttcher-Loschinski , A Stoll , C Flamann , S Richter , C Lischer , S Völkl , B Jacobs , M Böttcher , R Jitschin , H Bruns , T Fischer , E Holler , W Rösler , T Dandekar , A Mackensen , D Mougiakakos

Prevention of legionella infections from toilet flushing cisterns.

The Journal of hospital infection
Avec: L Bechmann , K Bauer , P Zerban , T Esser , A Tersteegen , S A Fuchs , A J Kaasch , D Wolleschak , E Schalk , T Fischer , D Mougiakakos , G Geginat

CD19 CAR T-Cell Therapy in Autoimmune Disease - A Case Series with Follow-up.

The New England journal of medicine
Avec: Fabian Müller , Jule Taubmann , Laura Bucci , Artur Wilhelm , Christina Bergmann , Simon Völkl , Michael Aigner , Tobias Rothe , Ioanna Minopoulou , Carlo Tur , Johannes Knitza , Soraya Kharboutli , Sascha Kretschmann , Ingrid Vasova , Silvia Spoerl , Hannah Reimann , Luis Munoz , Roman G Gerlach , Simon Schäfer , Ricardo Grieshaber-Bouyer , Anne-Sophie Korganow , Dominique Farge-Bancel , Dimitrios Mougiakakos , Aline Bozec , Thomas Winkler , Gerhard Krönke , Andreas Mackensen , Georg Schett

Low subcutaneous adipose tissue and myosteatosis are prognostic factors after allogeneic hematopoietic stem cell transplantation.

Clinical nutrition ESPEN
Avec: Felix Barajas Ordonez , Yannic Zeller , Denise Wolleschak , Mattes Hinnerichs , Pablo Rodríguez-Feria , Dimitrios Mougiakakos , Anar Aghayev , Hakan Kardas , Martin Mikusko , Jan Borggrefe , Alexey Surov

Inflammation-induced glycolytic switch controls suppressivity of mesenchymal stem cells via STAT1 glycosylation.

Leukemia
Avec: R Jitschin , M Böttcher , D Saul , S Lukassen , H Bruns , R Loschinski , A B Ekici , A Reis , A Mackensen , D Mougiakakos

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.

Immunity
Avec: Jasna Friščić , Martin Böttcher , Christiane Reinwald , Heiko Bruns , Benjamin Wirth , Samantha-Josefine Popp , Kellie Irene Walker , Jochen A Ackermann , Xi Chen , Jason Turner , Honglin Zhu , Lisa Seyler , Maximilien Euler , Philipp Kirchner , René Krüger , Arif B Ekici , Triin Major , Oliver Aust , Daniela Weidner , Anita Fischer , Fabian T Andes , Zeljka Stanojevic , Vladimir Trajkovic , Martin Herrmann , Adelheid Korb-Pap , Isabel Wank , Andreas Hess , Johnathan Winter , Viktor Wixler , Jörg Distler , Günter Steiner , Hans P Kiener , Benjamin Frey , Lasse Kling , Karim Raza , Silke Frey , Arnd Kleyer , Tobias Bäuerle , Timothy R Hughes , Anika Grüneboom , Ulrike Steffen , Gerhard Krönke , Adam P Croft , Andrew Filer , Jörg Köhl , Kerstin Klein , Christopher D Buckley , Georg Schett , Dimitrios Mougiakakos , Markus H Hoffmann

Noncanonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling.

Blood
Avec: S Oberbeck , A Schrader , K Warner , D Jungherz , G Crispatzu , J von Jan , M Chmielewski , A Ianevski , H H Diebner , P Mayer , A Kondo Ados , L Wahnschaffe , T Braun , T A Müller , P Wagle , A Bouska , T Neumann , S Pützer , L Varghese , N Pflug , M Thelen , J Makalowski , N Riet , H J M Göx , G Rappl , J Altmüller , M Kotrová , T Persigehl , G Hopfinger , M L Hansmann , H Schlößer , S Stilgenbauer , J Dürig , D Mougiakakos , M von Bergwelt-Baildon , I Roeder , S Hartmann , M Hallek , R Moriggl , M Brüggemann , T Aittokallio , J Iqbal , S Newrzela , H Abken , M Herling

Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis.

Journal for immunotherapy of cancer
Avec: Martin Böttcher , Heiko Bruns , Simon Völkl , Junyan Lu , Elisavet Chartomatsidou , Nikos Papakonstantinou , Kristin Mentz , Maike Büttner-Herold , Thorsten Zenz , Marco Herling , Wolfgang Huber , Paolo Ghia , Kostas Stamatopoulos , Andreas Mackensen , Dimitrios Mougiakakos

The IKZF1-IRF4/IRF5 Axis Controls Polarization of Myeloma-Associated Macrophages.

Cancer immunology research
Avec: Dimitrios Mougiakakos , Christian Bach , Martin Böttcher , Fabian Beier , Linda Röhner , Andrej Stoll , Michael Rehli , Claudia Gebhard , Christopher Lischer , Martin Eberhardt , Julio Vera , Maike Büttner-Herold , Katrin Bitterer , Heidi Balzer , Magdalena Leffler , Simon Jitschin , Michael Hundemer , Mohamed H S Awwad , Martin Busch , Steffen Stenger , Simon Völkl , Christian Schütz , Jan Krönke , Andreas Mackensen , Heiko Bruns

Thrombopoietin receptor agonists for acquired thrombocytopenia following anti-CD19 CAR-T-cell therapy: a case report.

Journal for immunotherapy of cancer
Avec: Rebecca Baur , Regina Jitschin , Soraya Kharboutli , Andrej Stoll , Simon Völkl , Maike Büttner-Herold , Daniela Schmidt , Wolf Rösler , Andreas Mackensen , Dimitrios Mougiakakos

Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus.

Nature medicine
Avec: Andreas Mackensen , Fabian Müller , Dimitrios Mougiakakos , Sebastian Böltz , Artur Wilhelm , Michael Aigner , Simon Völkl , David Simon , Arnd Kleyer , Luis Munoz , Sascha Kretschmann , Soraya Kharboutli , Regina Gary , Hannah Reimann , Wolf Rösler , Stefan Uderhardt , Holger Bang , Martin Herrmann , Arif Bülent Ekici , Christian Buettner , Katharina Marie Habenicht , Thomas H Winkler , Gerhard Krönke , Georg Schett

CT-defined sarcopenia predicts treatment response in primary central nervous system lymphomas.

European radiology
Avec: Alexey Surov , Hans Jonas Meyer , Mattes Hinnerichs , Vincenzo Ferraro , Vanja Zeremski , Dimitrios Mougiakakos , Sylvia Saalfeld , Andreas Wienke , Alexandra Strobel , Denise Wolleschak

Case Report: IBD-like colitis following CAR T cell therapy for diffuse large B cell lymphoma.

Frontiers in oncology
Avec: Sebastian Zundler , Francesco Vitali , Soraya Kharboutli , Simon Völkl , Iris Polifka , Andreas Mackensen , Raja Atreya , Markus F Neurath , Dimitrios Mougiakakos

Induction treatment in high-grade B-cell lymphoma with a concurrent

Frontiers in oncology
Avec: Vanja Zeremski , Siegfried Kropf , Michael Koehler , Niklas Gebauer , Ellen D McPhail , Thomas Habermann , Francesca Schieppati , Dimitrios Mougiakakos

Long-Term Survivors after Failure of Chimeric Antigen Receptor T Cell Therapy for Large B Cell Lymphoma: A Role for Allogeneic Hematopoietic Cell Transplantation? A German Lymphoma Alliance and German Registry for Stem Cell Transplantation Analysis.

Transplantation and cellular therapy
Avec: Patrick Derigs , Wolfgang A Bethge , Isabelle Krämer , Udo Holtick , Bastian von Tresckow , Francis Ayuk , Olaf Penack , Vladan Vucinic , Malte von Bonin , Claudia Baldus , Dimitrios Mougiakakos , Gerald Wulf , Ulf Schnetzke , Matthias Stelljes , Matthias Fante , Roland Schroers , Nicolaus Kroeger , Peter Dreger , Auteur inconnu

CAR T cells for treating autoimmune diseases.

RMD open
Avec: Ulrich Blache , Sandy Tretbar , Ulrike Koehl , Dimitrios Mougiakakos , Stephan Fricke

Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction.

eLife
Avec: Sara Latini , Veronica Venafra , Giorgia Massacci , Valeria Bica , Simone Graziosi , Giusj Monia Pugliese , Marta Iannuccelli , Filippo Frioni , Gessica Minnella , John Donald Marra , Patrizia Chiusolo , Gerardo Pepe , Manuela Helmer Citterich , Dimitros Mougiakakos , Martin Böttcher , Thomas Fischer , Livia Perfetto , Francesca Sacco

Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia.

Journal of hematology & oncology
Avec: Tobias Ronny Haage , Emmanouil Charakopoulos , Vikas Bhuria , Conny K Baldauf , Mark Korthals , Juliane Handschuh , Peter Müller , Juan Li , Kunjan Harit , Gopala Nishanth , Stephanie Frey , Martin Böttcher , Klaus-Dieter Fischer , Jan Dudeck , Anne Dudeck , Daniel B Lipka , Burkhart Schraven , Anthony R Green , Andreas J Müller , Dimitrios Mougiakakos , Thomas Fischer

Blockade of the CD47/SIRPα checkpoint axis potentiates the macrophage-mediated anti-tumor efficacy of tafasitamab.

Haematologica
Avec: Alexander Biedermann , Maria Patra-Kneuer , Dimitrios Mougiakakos , Maike Büttner-Herold , Doris Mangelberger-Eberl , Johannes Berges , Christian Kellner , Sarah Altmeyer , Jörg Thomas Bittenbring , Christian Augsberger , Kristina Ilieva-Babinsky , Stefan Haskamp , Fabian Beier , Christopher Lischer , Julio Vera , Anja Lührmann , Simone Bertz , Simon Völkl , Benedikt Jacobs , Stefan Steidl , Andreas Mackensen , Heiko Bruns

Advancements and challenges in CAR T cell therapy in autoimmune diseases.

Nature reviews. Rheumatology
Avec: Georg Schett , Fabian Müller , Jule Taubmann , Andreas Mackensen , Wei Wang , Rich A Furie , Ralf Gold , Aiden Haghikia , Peter A Merkel , Roberto Caricchio , Maria-Antonietta D'Agostino , Franco Locatelli , Carl H June , Dimitrios Mougiakakos

The Oncometabolite 5'-Deoxy-5'-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation.

Frontiers in immunology
Avec: Benedikt Jacobs , Sebastian Schlögl , Carolin Dorothea Strobl , Simon Völkl , Andrej Stoll , Dimitrios Mougiakakos , Karl-Johan Malmberg , Andreas Mackensen , Michael Aigner

Hydrogen-Peroxide Synthesis and LDL-Uptake Controls Immunosuppressive Properties in Monocyte-Derived Dendritic Cells.

Cancers
Avec: Ann-Katrin Menzner , Tanja Rottmar , Simon Voelkl , Jacobus J Bosch , Dimitrios Mougiakakos , Andreas Mackensen , Yazid J Resheq

Human Double-Negative Regulatory T-Cells Induce a Metabolic and Functional Switch in Effector T-Cells by Suppressing mTOR Activity.

Frontiers in immunology
Avec: Tabea Haug , Michael Aigner , Moritz M Peuser , Carolin D Strobl , Kai Hildner , Dimitrios Mougiakakos , Heiko Bruns , Andreas Mackensen , Simon Völkl

The Induction of a Permissive Environment to Promote T Cell Immune Evasion in Acute Myeloid Leukemia: The Metabolic Perspective.

Frontiers in oncology
Avec: Dimitrios Mougiakakos

Exploitable metabolic dependencies in MLL-ENL-induced leukemia.

Blood advances
Avec: Maria-Paz Garcia-Cuellar , Jennifer Lawlor , Martin Böttcher , Dimitrios Mougiakakos , Markus Metzler , Robert K Slany

CD137 (4-1BB) stimulation leads to metabolic and functional reprogramming of human monocytes/macrophages enhancing their tumoricidal activity.

Leukemia
Avec: A Stoll , H Bruns , M Fuchs , S Völkl , F Nimmerjahn , M Kunz , M Peipp , A Mackensen , D Mougiakakos

Anticancer Aminoferrocene Derivatives Inducing Production of Mitochondrial Reactive Oxygen Species.

Chemistry (Weinheim an der Bergstrasse, Germany)
Avec: Hülya Gizem Özkan , Vanrajsinh Thakor , Hong-Gui Xu , Galyna Bila , Rostyslav Bilyy , Daria Bida , Martin Böttcher , Dimitrios Mougiakakos , Rainer Tietze , Andriy Mokhir

Bone marrow stroma cells promote induction of a chemoresistant and prognostic unfavorable S100A8/A9high AML cell subset.

Blood advances
Avec: Martin Böttcher , Konstantinos Panagiotidis , Heiko Bruns , Martina Stumpf , Simon Völkl , Stefanie Geyh , Barbara Dietel , Thomas Schroeder , Andreas Mackensen , Dimitrios Mougiakakos

The metabolic profile of reconstituting T-cells, NK-cells, and monocytes following autologous stem cell transplantation and its impact on outcome.

Scientific reports
Avec: Silja Richter , Martin Böttcher , Simon Völkl , Andreas Mackensen , Evelyn Ullrich , Benedikt Jacobs , Dimitrios Mougiakakos

Increased PD-1 expression on circulating T-cells correlates with inferior outcome after autologous stem cell transplantation.

Transplantation and cellular therapy
Avec: Silja Richter , Martin Böttcher , Andrej Stoll , Vanja Zeremski , Simon Völkl , Andreas Mackensen , Arif B Ekici , Benedikt Jacobs , Dimitrios Mougiakakos

Lipotoxicity as a Barrier for T Cell-Based Therapies.

Biomolecules
Avec: Romy Böttcher-Loschinski , Judit Rial Saborido , Martin Böttcher , Sascha Kahlfuss , Dimitrios Mougiakakos

Successful Generation of CD19 Chimeric Antigen Receptor T Cells from Patients with Advanced Systemic Lupus Erythematosus.

Transplantation and cellular therapy
Avec: S Kretschmann , S Völkl , H Reimann , G Krönke , G Schett , S Achenbach , G Lutzny-Geier , F Müller , D Mougiakakos , J Dingfelder , C Flamann , L Hanssens , R Gary , A Mackensen , M Aigner

Pleiotropic effects of antibiotics on T cell metabolism and T cell-mediated immunity.

Frontiers in microbiology
Avec: Tobias Franz , Jonas Negele , Philipp Bruno , Martin Böttcher , Marisa Mitchell-Flack , Lea Reemts , Anna Krone , Dimitrios Mougiakakos , Andreas J Müller , Andreas E Zautner , Sascha Kahlfuss

Effects of the STAMP-inhibitor asciminib on T cell activation and metabolic fitness compared to tyrosine kinase inhibition by imatinib, dasatinib, and nilotinib.

Cancer immunology, immunotherapy : CII
Avec: Lukas Häselbarth , Axel Karow , Kristin Mentz , Martin Böttcher , Oisin Roche-Lancaster , Manuela Krumbholz , Regina Jitschin , Dimitrios Mougiakakos , Markus Metzler

TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment.

Frontiers in oncology
Avec: Nouria Jantz-Naeem , Romy Böttcher-Loschinski , Katrin Borucki , Marisa Mitchell-Flack , Martin Böttcher , Burkhart Schraven , Dimitrios Mougiakakos , Sascha Kahlfuss

Accumulation of T-cell-suppressive PD-L1

Journal for immunotherapy of cancer
Avec: Rebecca Baur , Franziska Karl , Romy Böttcher-Loschinski , Andrej Stoll , Simon Völkl , Andreas Gießl , Cindy Flamann , Heiko Bruns , Ursula Schlötzer-Schrehardt , Martin Böttcher , Denis M Schewe , Thomas Fischer , Regina Jitschin , Andreas Mackensen , Dimitrios Mougiakakos

Enhanced potency of immunotherapy against B-cell precursor acute lymphoblastic leukemia by combination of an Fc-engineered CD19 antibody and CD47 blockade.

HemaSphere
Avec: Denis M Schewe , Fotini Vogiatzi , Ira A Münnich , Tobias Zeller , Roland Windisch , Christian Wichmann , Kristina Müller , Hilal Bhat , Elisa Felix , Dimitrios Mougiakakos , Heiko Bruns , Lennart Lenk , Thomas Valerius , Andreas Humpe , Matthias Peipp , Christian Kellner

Réseau de co-auteurs

Martin Böttcher 28 collaborations
Andreas Mackensen 26 collaborations
Simon Völkl 17 collaborations
Georg Schett 12 collaborations
Heiko Bruns 10 collaborations
Gerhard Krönke 8 collaborations
Andrej Stoll 7 collaborations
Thomas Fischer 7 collaborations
Michael Aigner 6 collaborations
Vanja Zeremski 6 collaborations
D Mougiakakos 6 collaborations
Regina Jitschin 5 collaborations
Maike Büttner-Herold 5 collaborations
Benedikt Jacobs 5 collaborations
Cornelia Stoll 4 collaborations
Jule Taubmann 4 collaborations
Carina Scholtysek 4 collaborations
Domenica Saul 4 collaborations
Denise Wolleschak 4 collaborations
Mattes Hinnerichs 4 collaborations
Alexey Surov 4 collaborations
Aiden Haghikia 4 collaborations
Roland Schroers 4 collaborations
Fabian Müller 4 collaborations
Rebecca Baur 4 collaborations
Julio Vera 4 collaborations
Burkhart Schraven 4 collaborations
Romy Böttcher-Loschinski 4 collaborations
A Mackensen 4 collaborations
Soraya Kharboutli 4 collaborations
Brenda Krishnacoumar 3 collaborations
Francis Ayuk 3 collaborations
Marion Subklewe 3 collaborations
Maria Faas 3 collaborations
Stefan Uderhardt 3 collaborations
Arnd Kleyer 3 collaborations
Anika Grüneboom 3 collaborations
Jörg Hofmann 3 collaborations
Ralf Gold 3 collaborations
Markus F Neurath 3 collaborations
Udo Holtick 3 collaborations
Olaf Penack 3 collaborations
Christian Koenecke 3 collaborations
Vladan Vucinic 3 collaborations
Peter Dreger 3 collaborations
Judit Rial Saborido 3 collaborations
Artur Wilhelm 3 collaborations
Aline Bozec 3 collaborations
Mirjeta Berisha 3 collaborations
Junyan Lu 3 collaborations
Thorsten Zenz 3 collaborations
Wolfgang Huber 3 collaborations
Martin Eberhardt 3 collaborations
Philipp Kirchner 3 collaborations
Arif B Ekici 3 collaborations
Andreas J Müller 3 collaborations
Markus Metzler 3 collaborations
S Völkl 3 collaborations
H Bruns 3 collaborations
Sascha Kahlfuss 3 collaborations
Jana Thomas 2 collaborations
Martin Boettcher 2 collaborations
Sebastian R Schulz 2 collaborations
Sophia Urbanczyk 2 collaborations
Dirk Mielenz 2 collaborations
Dorothea I H Müller 2 collaborations
Katrin Palumbo-Zerr 2 collaborations
Christina Böhm 2 collaborations
Natacha Ipseiz 2 collaborations
Max Zimmermann 2 collaborations
Jan Tuckermann 2 collaborations
Friederike Berberich-Siebelt 2 collaborations
Kai Rejeski 2 collaborations
Ariel Perez 2 collaborations
Eva Hoster 2 collaborations
Liv Jentzsch 2 collaborations
Veit Bücklein 2 collaborations
Viktoria Blumenberg 2 collaborations
Oliver Weigert 2 collaborations
Frederick L Locke 2 collaborations
Michael von Bergwelt-Baildon 2 collaborations
Wolfgang Bethge 2 collaborations
Michael D Jain 2 collaborations
Felix Barajas Ordonez 2 collaborations
Yannic Zeller 2 collaborations
Pablo Rodríguez-Feria 2 collaborations
Anar Aghayev 2 collaborations
Martin Mikusko 2 collaborations
Jan Borggrefe 2 collaborations
David Chambers 2 collaborations
R Verena Taudte 2 collaborations
Uwe Sonnewald 2 collaborations
David Simon 2 collaborations
Jeremias Motte 2 collaborations
Melissa Sgodzai 2 collaborations
Dominic Borie 2 collaborations
Wolfgang A Bethge 2 collaborations
Bastian von Tresckow 2 collaborations
Ulf Schnetzke 2 collaborations
Malte von Bonin 2 collaborations
Matthias Stelljes 2 collaborations
Bertram Glass 2 collaborations
Simone Thomas 2 collaborations
Nicolaus Kroeger 2 collaborations
Ricardo Grieshaber-Bouyer 2 collaborations
Thomas Winkler 2 collaborations
Tobias Ronny Haage 2 collaborations
Konstantinos Panagiotidis 2 collaborations
Franziska Karl 2 collaborations
Michael Hudecek 2 collaborations
Sascha Dietrich 2 collaborations
Niklas Gebauer 2 collaborations
Gerald Wulf 2 collaborations
Lars Bullinger 2 collaborations
Christian Bach 2 collaborations
Stefan Haskamp 2 collaborations
Cindy Flamann 2 collaborations
Katrin Bitterer 2 collaborations
Vincenzo Ferraro 2 collaborations
Andreas Wienke 2 collaborations
Alexandra Strobel 2 collaborations
Jasna Friščić 2 collaborations
Christiane Reinwald 2 collaborations
Maximilien Euler 2 collaborations
Xi Chen 2 collaborations
Honglin Zhu 2 collaborations
Benjamin Wirth 2 collaborations
Daniela Weidner 2 collaborations
René Krüger 2 collaborations
Vladimir Trajkovic 2 collaborations
Kerstin Klein 2 collaborations
Markus H Hoffmann 2 collaborations
Giorgia Massacci 2 collaborations
Veronica Venafra 2 collaborations
Sara Latini 2 collaborations
Valeria Bica 2 collaborations
Giusj Monia Pugliese 2 collaborations
Simone Graziosi 2 collaborations
Livia Perfetto 2 collaborations
Francesca Sacco 2 collaborations
Anna Krone 2 collaborations
Sascha Kahlfuß 2 collaborations
Vikas Bhuria 2 collaborations
Tobias Franz 2 collaborations
Carolin Dorothea Strobl 2 collaborations
Tabea Haug 2 collaborations
Tobias Rothe 2 collaborations
Ursula Schlötzer-Schrehardt 2 collaborations
Lukas Häselbarth 2 collaborations
Manuela Krumbholz 2 collaborations
Axel Karow 2 collaborations
Siegfried Kropf 2 collaborations
A Stoll 2 collaborations
C Flamann 2 collaborations
M Böttcher 2 collaborations
R Jitschin 2 collaborations
T Fischer 2 collaborations
Sascha Kretschmann 2 collaborations
Hannah Reimann 2 collaborations
Luis Munoz 2 collaborations
Martin Herrmann 2 collaborations
Kristin Mentz 2 collaborations
Fabian Beier 2 collaborations
Christopher Lischer 2 collaborations
Wolf Rösler 2 collaborations
Christian Kellner 2 collaborations
Silja Richter 2 collaborations
Marisa Mitchell-Flack 2 collaborations
Denis M Schewe 2 collaborations
Dorothea Reimer 1 collaboration
Michael Meyer-Hermann 1 collaboration
Asylkhan Rakhymzhan 1 collaboration
Tobit Steinmetz 1 collaboration
Philipp Tripal 1 collaboration
Anja E Hauser 1 collaboration
Raluca A Niesner 1 collaboration
Farida Djouad 1 collaboration
Snigdha Majumder 1 collaboration
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Luisa Bell 1 collaboration
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Rishav Seal 1 collaboration
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Pierre Sesques 1 collaboration
Carolina Berger 1 collaboration
Lisa Frölich 1 collaboration
Josephine Ackermann 1 collaboration
Christian Schmidt 1 collaboration
Laurent Jallades 1 collaboration
Boris Fehse 1 collaboration
Christoph Faul 1 collaboration
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Martin Dreyling 1 collaboration
Emmanuel Bachy 1 collaboration
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Markus Kieler 1 collaboration
Melanie Hofmann 1 collaboration
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Gernot Schabbauer 1 collaboration
Fabian Hartmann 1 collaboration
Susetta Finotto 1 collaboration
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Thomas Mika 1 collaboration
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Thomas Tüting 1 collaboration
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Felix Jost 1 collaboration
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Simon Faissner 1 collaboration
Christian Geis 1 collaboration
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Gui-Wei He 1 collaboration
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Hardikkumar Jetani 1 collaboration
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F Karl 1 collaboration
C Liang 1 collaboration
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S Richter 1 collaboration
C Lischer 1 collaboration
B Jacobs 1 collaboration
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T Esser 1 collaboration
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E Schalk 1 collaboration
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Simon Schäfer 1 collaboration
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Hakan Kardas 1 collaboration
D Saul 1 collaboration
S Lukassen 1 collaboration
R Loschinski 1 collaboration
A B Ekici 1 collaboration
A Reis 1 collaboration
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Kellie Irene Walker 1 collaboration
Jochen A Ackermann 1 collaboration
Jason Turner 1 collaboration
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K Warner 1 collaboration
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P Mayer 1 collaboration
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T Braun 1 collaboration
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I Roeder 1 collaboration
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None None 1 collaboration
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Mark Korthals 1 collaboration
Juliane Handschuh 1 collaboration
Peter Müller 1 collaboration
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Jan Dudeck 1 collaboration
Anne Dudeck 1 collaboration
Daniel B Lipka 1 collaboration
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Wei Wang 1 collaboration
Rich A Furie 1 collaboration
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Robert K Slany 1 collaboration
M Fuchs 1 collaboration
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M Kunz 1 collaboration
M Peipp 1 collaboration
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Barbara Dietel 1 collaboration
Thomas Schroeder 1 collaboration
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S Kretschmann 1 collaboration
H Reimann 1 collaboration
G Krönke 1 collaboration
G Schett 1 collaboration
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F Müller 1 collaboration
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L Hanssens 1 collaboration
R Gary 1 collaboration
M Aigner 1 collaboration
Jonas Negele 1 collaboration
Philipp Bruno 1 collaboration
Lea Reemts 1 collaboration
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Roland Windisch 1 collaboration
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Hilal Bhat 1 collaboration
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Matthias Peipp 1 collaboration