Andreas Mackensen

Affiliations
  • Department of Medicine 5 for Hematology and Oncology, Friedrich-Alexander-Universität Erlangen-Nuremberg, Erlangen, Germany.

Publications (76)

N-glycosylation controls inflammatory licensing-triggered PD-L1 upregulation in human mesenchymal stromal cells.

Stem cells (Dayton, Ohio)
Avec: Vivien Strauch , Domenica Saul , Mirjeta Berisha , Andreas Mackensen , Dimitrios Mougiakakos , Regina Jitschin

Selective PRMT5 Inhibitors Suppress Human CD8

Molecular cancer therapeutics
Avec: Carolin Dorothea Strobl , Stefanie Schaffer , Tabea Haug , Simon Völkl , Katrin Peter , Katrin Singer , Martin Böttcher , Dimitrios Mougiakakos , Andreas Mackensen , Michael Aigner

Human CD22-Transgenic, Primary Murine Lymphoma Challenges Immunotherapies in Organ-Specific Tumor Microenvironments.

International journal of molecular sciences
Avec: Franziska Gsottberger , Carolin Brandl , Kerstin Wendland , Srdjan Petkovic , Charlotte Emmerich , Ramona Erber , Carol Geppert , Arndt Hartmann , Andreas Mackensen , Lars Nitschke , Fabian Müller

The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL.

Journal for immunotherapy of cancer
Avec: Kai Rejeski , Ariel Perez , Gloria Iacoboni , Olaf Penack , Veit Bücklein , Liv Jentzsch , Dimitrios Mougiakakos , Grace Johnson , Brian Arciola , Cecilia Carpio , Viktoria Blumenberg , Eva Hoster , Lars Bullinger , Frederick L Locke , Michael von Bergwelt-Baildon , Andreas Mackensen , Wolfgang Bethge , Pere Barba , Michael D Jain , Marion Subklewe

Identification of Disparities in Personalized Cancer Care-A Joint Approach of the German WERA Consortium.

Cancers
Avec: Florian Lüke , Florian Haller , Kirsten Utpatel , Markus Krebs , Norbert Meidenbauer , Alexander Scheiter , Silvia Spoerl , Daniel Heudobler , Daniela Sparrer , Ulrich Kaiser , Felix Keil , Christoph Schubart , Lars Tögel , Sabine Einhell , Wolfgang Dietmaier , Ralf Huss , Sebastian Dintner , Sebastian Sommer , Frank Jordan , Maria-Elisabeth Goebeler , Michaela Metz , Diana Haake , Mithun Scheytt , Elena Gerhard-Hartmann , Katja Maurus , Stephanie Brändlein , Andreas Rosenwald , Arndt Hartmann , Bruno Märkl , Hermann Einsele , Andreas Mackensen , Wolfgang Herr , Volker Kunzmann , Ralf Bargou , Matthias W Beckmann , Tobias Pukrop , Martin Trepel , Matthias Evert , Rainer Claus , Alexander Kerscher

Inferior Outcomes of EU Versus US Patients Treated With CD19 CAR-T for Relapsed/Refractory Large B-cell Lymphoma: Association With Differences in Tumor Burden, Systemic Inflammation, Bridging Therapy Utilization, and CAR-T Product Use.

HemaSphere
Avec: Veit Bücklein , Ariel Perez , Kai Rejeski , Gloria Iacoboni , Vindi Jurinovic , Udo Holtick , Olaf Penack , Soraya Kharboutli , Viktoria Blumenberg , Josephine Ackermann , Lisa Frölich , Grace Johnson , Kedar Patel , Brian Arciola , Rahul Mhaskar , Anthony Wood , Christian Schmidt , Omar Albanyan , Philipp Gödel , Eva Hoster , Lars Bullinger , Andreas Mackensen , Frederick Locke , Michael von Bergwelt , Pere Barba , Marion Subklewe , Michael D Jain

Oxidative DNA damage in reconstituting T cells is associated with relapse and inferior survival after allo-SCT.

Blood
Avec: F Karl , C Liang , R Böttcher-Loschinski , A Stoll , C Flamann , S Richter , C Lischer , S Völkl , B Jacobs , M Böttcher , R Jitschin , H Bruns , T Fischer , E Holler , W Rösler , T Dandekar , A Mackensen , D Mougiakakos

CD19 CAR T-Cell Therapy in Autoimmune Disease - A Case Series with Follow-up.

The New England journal of medicine
Avec: Fabian Müller , Jule Taubmann , Laura Bucci , Artur Wilhelm , Christina Bergmann , Simon Völkl , Michael Aigner , Tobias Rothe , Ioanna Minopoulou , Carlo Tur , Johannes Knitza , Soraya Kharboutli , Sascha Kretschmann , Ingrid Vasova , Silvia Spoerl , Hannah Reimann , Luis Munoz , Roman G Gerlach , Simon Schäfer , Ricardo Grieshaber-Bouyer , Anne-Sophie Korganow , Dominique Farge-Bancel , Dimitrios Mougiakakos , Aline Bozec , Thomas Winkler , Gerhard Krönke , Andreas Mackensen , Georg Schett

Preclinical Development of CAR T Cells with Antigen-Inducible IL18 Enforcement to Treat GD2-Positive Solid Cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research
Avec: Lena Fischer-Riepe , Sareetha Kailayangiri , Katharina Zimmermann , Rita Pfeifer , Michael Aigner , Bianca Altvater , Sascha Kretschmann , Simon Völkl , Jordan Hartley , Celine Dreger , Katja Petry , Andreas Bosio , Angelika von Döllen , Wolfgang Hartmann , Holger Lode , Dennis Görlich , Andreas Mackensen , Melanie Jungblut , Axel Schambach , Hinrich Abken , Claudia Rossig

The WERA cancer center matrix: Strategic management of patient access to precision oncology in a large and mostly rural area of Germany.

European journal of cancer (Oxford, England : 1990)
Avec: Markus Krebs , Florian Haller , Silvia Spörl , Elena Gerhard-Hartmann , Kirsten Utpatel , Katja Maurus , Volker Kunzmann , Manik Chatterjee , Vivek Venkataramani , Imad Maatouk , Max Bittrich , Tatjana Einwag , Norbert Meidenbauer , Lars Tögel , Daniela Hirsch , Wolfgang Dietmaier , Felix Keil , Alexander Scheiter , Alexander Immel , Daniel Heudobler , Sabine Einhell , Ulrich Kaiser , Anja M Sedlmeier , Julia Maurer , Gerhard Schenkirsch , Frank Jordan , Maximilian Schmutz , Sebastian Dintner , Andreas Rosenwald , Arndt Hartmann , Matthias Evert , Bruno Märkl , Ralf Bargou , Andreas Mackensen , Matthias W Beckmann , Tobias Pukrop , Wolfgang Herr , Hermann Einsele , Martin Trepel , Maria-Elisabeth Goebeler , Rainer Claus , Alexander Kerscher , Florian Lüke

A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS.

The Journal of experimental medicine
Avec: Maria Elena Maccari , Sebastian Fuchs , Patrick Kury , Geoffroy Andrieux , Simon Völkl , Bertram Bengsch , Myriam Ricarda Lorenz , Maximilian Heeg , Jan Rohr , Sabine Jägle , Carla N Castro , Miriam Groß , Ursula Warthorst , Christoph König , Ilka Fuchs , Carsten Speckmann , Julian Thalhammer , Friedrich G Kapp , Markus G Seidel , Gregor Dückers , Stefan Schönberger , Catharina Schütz , Marita Führer , Robin Kobbe , Dirk Holzinger , Christian Klemann , Petr Smisek , Stephen Owens , Gerd Horneff , Reinhard Kolb , Nora Naumann-Bartsch , Maurizio Miano , Julian Staniek , Marta Rizzi , Tomas Kalina , Pascal Schneider , Anika Erxleben , Rolf Backofen , Arif Ekici , Charlotte M Niemeyer , Klaus Warnatz , Bodo Grimbacher , Hermann Eibel , Andreas Mackensen , Andreas Philipp Frei , Klaus Schwarz , Melanie Boerries , Stephan Ehl , Anne Rensing-Ehl

CAR-HEMATOTOX: a model for CAR T-cell-related hematologic toxicity in relapsed/refractory large B-cell lymphoma.

Blood
Avec: Kai Rejeski , Ariel Perez , Pierre Sesques , Eva Hoster , Carolina Berger , Liv Jentzsch , Dimitrios Mougiakakos , Lisa Frölich , Josephine Ackermann , Veit Bücklein , Viktoria Blumenberg , Christian Schmidt , Laurent Jallades , Boris Fehse , Christoph Faul , Philipp Karschnia , Oliver Weigert , Martin Dreyling , Frederick L Locke , Michael von Bergwelt-Baildon , Andreas Mackensen , Wolfgang Bethge , Francis Ayuk , Emmanuel Bachy , Gilles Salles , Michael D Jain , Marion Subklewe

Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy.

Journal for immunotherapy of cancer
Avec: Hannah Reimann , Andrew Nguyen , J Zachary Sanborn , Charles J Vaske , Stephen C Benz , Kayvan Niazi , Shahrooz Rabizadeh , Patricia Spilman , Andreas Mackensen , Matthias Ruebner , Alexander Hein , Matthias W Beckmann , Edith D van der Meijden , Judith Bausenwein , Sascha Kretschmann , Marieke Griffioen , Jeffrey Schlom , James L Gulley , Karin L Lee , Duane H Hamilton , Patrick Soon-Shiong , Peter A Fasching , Anita N Kremer

CD19 CAR-T cell treatment: Unraveling the role of B cells in Systemic Lupus Erythematosus.

Arthritis & rheumatology (Hoboken, N.J.)
Avec: Jule Taubmann , Fabian Müller , Melek Yalcin Mutlu , Simon Völkl , Michael Aigner , Aline Bozec , Andreas Mackensen , Ricardo Grieshaber-Bouyer , Georg Schett

Innovative cellular therapies for autoimmune diseases: expert-based position statement and clinical practice recommendations from the EBMT practice harmonization and guidelines committee.

EClinicalMedicine
Avec: Raffaella Greco , Tobias Alexander , Nicoletta Del Papa , Fabian Müller , Riccardo Saccardi , Fermin Sanchez-Guijo , Georg Schett , Basil Sharrack , John A Snowden , Karin Tarte , Francesco Onida , Isabel Sánchez-Ortega , Joachim Burman , Cristina Castilla Llorente , Ricard Cervera , Fabio Ciceri , Andrea Doria , Jörg Henes , James Lindsay , Andreas Mackensen , Paolo A Muraro , Elena Ricart , Montserrat Rovira , Tsila Zuckerman , Ibrahim Yakoub-Agha , Dominique Farge

Role of CAR T Cell Metabolism for Therapeutic Efficacy.

Cancers
Avec: Judit Rial Saborido , Simon Völkl , Michael Aigner , Andreas Mackensen , Dimitrios Mougiakakos

Identification and characterization of T-cell receptors with therapeutic potential showing conserved specificity against all SARS-CoV 2 strains.

Immunobiology
Avec: Hannah Reimann , Carolin Moosmann , Kilian Schober , Vanessa Lang , Johan Verhagen , Julia Zeun , Andreas Mackensen , Anita N Kremer , Simon Völkl , Michael Aigner

CAR T-cell therapy in autoimmune diseases.

Lancet (London, England)
Avec: Georg Schett , Andreas Mackensen , Dimitrios Mougiakakos

Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion.

Science advances
Avec: Kai Rejeski , Ariel Perez , Gloria Iacoboni , Viktoria Blumenberg , Veit L Bücklein , Simon Völkl , Olaf Penack , Omar Albanyan , Sophia Stock , Fabian Müller , Philipp Karschnia , Agnese Petrera , Kayla Reid , Rawan Faramand , Marco L Davila , Karnav Modi , Erin A Dean , Christina Bachmeier , Michael von Bergwelt-Baildon , Frederick L Locke , Wolfgang Bethge , Lars Bullinger , Andreas Mackensen , Pere Barba , Michael D Jain , Marion Subklewe

Prevention of CMV/EBV reactivation by double-specific T cells in patients after allogeneic stem cell transplantation: results from the randomized phase I/IIa MULTIVIR-01 study.

Frontiers in immunology
Avec: Armin Gerbitz , Regina Gary , Michael Aigner , Andreas Moosmann , Anita Kremer , Christoph Schmid , Klaus Hirschbuehl , Eva Wagner , Beate Hauptrock , Daniel Teschner , Wolf Roesler , Bernd Spriewald , Johanna Tischer , Stephanie Moi , Heidi Balzer , Stefanie Schaffer , Judith Bausenwein , Anja Wagner , Franziska Schmidt , Jens Brestrich , Barbara Ullrich , Stefanie Maas , Susanne Herold , Julian Strobel , Robert Zimmermann , Volker Weisbach , Leo Hansmann , Fernanda Lammoglia-Cobo , Mats Remberger , Matthias Stelljes , Francis Ayuk , Robert Zeiser , Andreas Mackensen

Adoptive transfer of donor-B lymphocytes: a phase I/IIa study for patients after allogeneic stem cell transplantation.

Blood advances
Avec: Julia Winkler , Hannes Tittlbach , Andrea Schneider , Ingrid Vasova , Julian Strobel , Susanne Herold , Stefanie Maas , Bernd M Spriewald , Roland Repp , Lambros Kordelas , Michael Mach , Daniel Wolff , Matthias Edinger , Andreas Mackensen , Thomas H Winkler

Selective CAR-T cell mediated B cell depletion suppresses interferon signature in SLE.

JCI insight
Avec: Artur Wilhelm , David Chambers , Fabian Müller , Aline Bozec , Ricardo Grieshaber-Bouyer , Thomas Winkler , Dimitrios Mougiakakos , Andreas Mackensen , Georg Schett , Gerhard Krönke

[CAR T-cell therapy in rheumatology-What we know so far?]

Zeitschrift fur Rheumatologie
Avec: Melanie Hagen , Andreas Wirsching , Daniela Bohr , Jule Taubmann , Fabian Müller , Andreas Mackensen , Ricardo Grieshaber-Bouyer , Georg Schett

Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome.

Nature cancer
Avec: Janaki Manoja Vinnakota , Francesca Biavasco , Marius Schwabenland , Chintan Chhatbar , Rachael C Adams , Daniel Erny , Sandra Duquesne , Nadia El Khawanky , Dominik Schmidt , Viktor Fetsch , Alexander Zähringer , Henrike Salié , Dimitrios Athanassopoulos , Lukas M Braun , Nora R Javorniczky , Jenny N H G Ho , Katrin Kierdorf , Reinhard Marks , Ralph Wäsch , Federico Simonetta , Geoffroy Andrieux , Dietmar Pfeifer , Gianni Monaco , Christian Capitini , Terry J Fry , Thomas Blank , Bruce R Blazar , Eva Wagner , Matthias Theobald , Clemens Sommer , Matthias Stelljes , Christian Reicherts , Astrid Jeibmann , Jens Schittenhelm , Camelia-Maria Monoranu , Andreas Rosenwald , Martin Kortüm , Leo Rasche , Hermann Einsele , Philipp T Meyer , Joachim Brumberg , Simon Völkl , Andreas Mackensen , Roland Coras , Michael von Bergwelt-Baildon , Nathalie L Albert , Laura M Bartos , Matthias Brendel , Adrien Holzgreve , Matthias Mack , Melanie Boerries , Crystal L Mackall , Justus Duyster , Philipp Henneke , Josef Priller , Natalie Köhler , Felix Strübing , Bertram Bengsch , Marco Ruella , Marion Subklewe , Louisa von Baumgarten , Saar Gill , Marco Prinz , Robert Zeiser

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase.

Frontiers in immunology
Avec: Anita N Kremer , Judith Bausenwein , Ellie Lurvink , Andreas E Kremer , Caroline E Rutten , Cornelis A M van Bergen , Sascha Kretschmann , Edith van der Meijden , Maria W Honders , Daniela Mazzeo , Colin Watts , Andreas Mackensen , J H Frederik Falkenburg , Marieke Griffioen

Inflammation-induced glycolytic switch controls suppressivity of mesenchymal stem cells via STAT1 glycosylation.

Leukemia
Avec: R Jitschin , M Böttcher , D Saul , S Lukassen , H Bruns , R Loschinski , A B Ekici , A Reis , A Mackensen , D Mougiakakos

Deciphering the Variability in Mg/Ca and Stable Oxygen Isotopes of Individual Foraminifera.

Paleoceanography and paleoclimatology
Avec: Jeroen Groeneveld , Sze Ling Ho , Andreas Mackensen , Mahyar Mohtadi , Thomas Laepple

Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.

The Journal of clinical investigation
Avec: Sascha Kretschmann , Stefanie Herda , Heiko Bruns , Josefine Russ , Edith D van der Meijden , Ursula Schlötzer-Schrehardt , Marieke Griffioen , Il-Kang Na , Andreas Mackensen , Anita N Kremer

Upregulation of CCR4 in activated CD8

European journal of immunology
Avec: Silvia Spoerl , Anita N Kremer , Michael Aigner , Nina Eisenhauer , Pauline Koch , Lina Meretuk , Patrick Löffler , Matthias Tenbusch , Clara Maier , Klaus Überla , Lucie Heinzerling , Benjamin Frey , Gloria Lutzny-Geier , Thomas H Winkler , Gerhard Krönke , Marcel Vetter , Heiko Bruns , Markus F Neurath , Andreas Mackensen , Andreas E Kremer , Simon Völkl

Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis.

Journal for immunotherapy of cancer
Avec: Martin Böttcher , Heiko Bruns , Simon Völkl , Junyan Lu , Elisavet Chartomatsidou , Nikos Papakonstantinou , Kristin Mentz , Maike Büttner-Herold , Thorsten Zenz , Marco Herling , Wolfgang Huber , Paolo Ghia , Kostas Stamatopoulos , Andreas Mackensen , Dimitrios Mougiakakos

The IKZF1-IRF4/IRF5 Axis Controls Polarization of Myeloma-Associated Macrophages.

Cancer immunology research
Avec: Dimitrios Mougiakakos , Christian Bach , Martin Böttcher , Fabian Beier , Linda Röhner , Andrej Stoll , Michael Rehli , Claudia Gebhard , Christopher Lischer , Martin Eberhardt , Julio Vera , Maike Büttner-Herold , Katrin Bitterer , Heidi Balzer , Magdalena Leffler , Simon Jitschin , Michael Hundemer , Mohamed H S Awwad , Martin Busch , Steffen Stenger , Simon Völkl , Christian Schütz , Jan Krönke , Andreas Mackensen , Heiko Bruns

Sorafenib or placebo in patients with newly diagnosed acute myeloid leukaemia: long-term follow-up of the randomized controlled SORAML trial.

Leukemia
Avec: Christoph Röllig , Hubert Serve , Richard Noppeney , Maher Hanoun , Utz Krug , Claudia D Baldus , Christian H Brandts , Volker Kunzmann , Hermann Einsele , Alwin Krämer , Carsten Müller-Tidow , Kerstin Schäfer-Eckart , Andreas Neubauer , Andreas Burchert , Aristoteles Giagounidis , Stefan W Krause , Andreas Mackensen , Walter Aulitzky , Regina Herbst , Mathias Hänel , Norbert Frickhofen , Johannes Kullmer , Ulrich Kaiser , Alexander Kiani , Hartmut Link , Thomas Geer , Albrecht Reichle , Christian Junghanß , Roland Repp , Achim Meinhardt , Heinz Dürk , Ina-Maria Klut , Martin Bornhäuser , Markus Schaich , Stefani Parmentier , Martin Görner , Christian Thiede , Malte von Bonin , Uwe Platzbecker , Johannes Schetelig , Michael Kramer , Wolfgang E Berdel , Gerhard Ehninger , Auteur inconnu

Triton X-114 and Amine-Based Wash Strategy Reduces Lipopolysaccharides to FDA Limit and Achieves Purer, More Potent Recombinant Immunotoxin.

Bioconjugate chemistry
Avec: Rebekka George , Franziska Gsottberger , Anna Ammon , Kerstin Wendland , Lisa Mellenthin , Andreas Mackensen , Fabian Müller

Variable Expression of the Disialoganglioside GD2 in Breast Cancer Molecular Subtypes.

Cancers
Avec: Ramona Erber , Sareetha Kailayangiri , Hanna Huebner , Matthias Ruebner , Arndt Hartmann , Lothar Häberle , Julia Meyer , Simon Völkl , Andreas Mackensen , Laura Landgraf , Carol I Geppert , Rüdiger Schulz-Wendtland , Matthias W Beckmann , Peter A Fasching , Nicole Farwick , Claudia Rossig , Paul Gass

Thrombopoietin receptor agonists for acquired thrombocytopenia following anti-CD19 CAR-T-cell therapy: a case report.

Journal for immunotherapy of cancer
Avec: Rebecca Baur , Regina Jitschin , Soraya Kharboutli , Andrej Stoll , Simon Völkl , Maike Büttner-Herold , Daniela Schmidt , Wolf Rösler , Andreas Mackensen , Dimitrios Mougiakakos

Midkine Promotes Metastasis and Therapeutic Resistance via mTOR/RPS6 in Uveal Melanoma.

Molecular cancer research : MCR
Avec: Margarete M Karg , Lukas John , Nasrin Refaian , Christian Buettner , Tanja Rottmar , Jonas Sommer , Barbara Bock , Yazid J Resheq , Bruce R Ksander , Ludwig M Heindl , Andreas Mackensen , Jacobus J Bosch

Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus.

Nature medicine
Avec: Andreas Mackensen , Fabian Müller , Dimitrios Mougiakakos , Sebastian Böltz , Artur Wilhelm , Michael Aigner , Simon Völkl , David Simon , Arnd Kleyer , Luis Munoz , Sascha Kretschmann , Soraya Kharboutli , Regina Gary , Hannah Reimann , Wolf Rösler , Stefan Uderhardt , Holger Bang , Martin Herrmann , Arif Bülent Ekici , Christian Buettner , Katharina Marie Habenicht , Thomas H Winkler , Gerhard Krönke , Georg Schett

Case Report: IBD-like colitis following CAR T cell therapy for diffuse large B cell lymphoma.

Frontiers in oncology
Avec: Sebastian Zundler , Francesco Vitali , Soraya Kharboutli , Simon Völkl , Iris Polifka , Andreas Mackensen , Raja Atreya , Markus F Neurath , Dimitrios Mougiakakos

Blockade of the CD47/SIRPα checkpoint axis potentiates the macrophage-mediated anti-tumor efficacy of tafasitamab.

Haematologica
Avec: Alexander Biedermann , Maria Patra-Kneuer , Dimitrios Mougiakakos , Maike Büttner-Herold , Doris Mangelberger-Eberl , Johannes Berges , Christian Kellner , Sarah Altmeyer , Jörg Thomas Bittenbring , Christian Augsberger , Kristina Ilieva-Babinsky , Stefan Haskamp , Fabian Beier , Christopher Lischer , Julio Vera , Anja Lührmann , Simone Bertz , Simon Völkl , Benedikt Jacobs , Stefan Steidl , Andreas Mackensen , Heiko Bruns

Advancements and challenges in CAR T cell therapy in autoimmune diseases.

Nature reviews. Rheumatology
Avec: Georg Schett , Fabian Müller , Jule Taubmann , Andreas Mackensen , Wei Wang , Rich A Furie , Ralf Gold , Aiden Haghikia , Peter A Merkel , Roberto Caricchio , Maria-Antonietta D'Agostino , Franco Locatelli , Carl H June , Dimitrios Mougiakakos

Palmitoylated Proteins on AML-Derived Extracellular Vesicles Promote Myeloid-Derived Suppressor Cell Differentiation via TLR2/Akt/mTOR Signaling.

Cancer research
Avec: Sehmus Tohumeken , Rebecca Baur , Martin Böttcher , Andrej Stoll , Romy Loschinski , Konstantinos Panagiotidis , Martina Braun , Domenica Saul , Simon Völkl , Andreas S Baur , Heiko Bruns , Andreas Mackensen , Regina Jitschin , Dimitrios Mougiakakos

Design and Implementation of a Single Source Multipurpose Hospital-Wide Clinical Trial Registry.

Studies in health technology and informatics
Avec: Marcus Sommer , Melanie Kirchner , Christian Gulden , Sainab Egloffstein , Michael Patrick Lux , Matthias Wilhelm Beckmann , Andreas Mackensen , Hans-Ulrich Prokosch

Characterization of CD4+ T cells primed and boosted by MHCII primary uveal melanoma cell-based vaccines.

Oncotarget
Avec: Julia M Kittler , Jonas Sommer , Anika Fischer , Sabine Britting , Margarete M Karg , Barbara Bock , Imke Atreya , Ludwig M Heindl , Andreas Mackensen , Jacobus J Bosch

An Easily Expandable Multi-Drug LC-MS Assay for the Simultaneous Quantification of 57 Oral Antitumor Drugs in Human Plasma.

Cancers
Avec: Niklas Kehl , Katja Schlichtig , Pauline Dürr , Laura Bellut , Frank Dörje , Rainer Fietkau , Marianne Pavel , Andreas Mackensen , Bernd Wullich , Renke Maas , Martin F Fromm , Arne Gessner , R Verena Taudte

T-Cell Metabolism in Graft

Frontiers in immunology
Avec: Franziska Karl , Michael Hudecek , Friederike Berberich-Siebelt , Andreas Mackensen , Dimitrios Mougiakakos

Linking Immunoevasion and Metabolic Reprogramming in B-Cell-Derived Lymphomas.

Frontiers in oncology
Avec: Martin Böttcher , Rebecca Baur , Andrej Stoll , Andreas Mackensen , Dimitrios Mougiakakos

Immune modulatory effects of Idelalisib in stromal cells of chronic lymphocytic leukemia.

Leukemia & lymphoma
Avec: Sarah Handl , Franziska von Heydebrand , Simon Voelkl , Robert A J Oostendorp , Jochen Wilke , Anita N Kremer , Andreas Mackensen , Gloria Lutzny-Geier

Protein kinase C-β-dependent changes in the glucose metabolism of bone marrow stromal cells of chronic lymphocytic leukemia.

Stem cells (Dayton, Ohio)
Avec: Franziska von Heydebrand , Maximilian Fuchs , Meik Kunz , Simon Voelkl , Anita N Kremer , Robert A J Oostendorp , Jochen Wilke , Michael Leitges , Alexander Egle , Andreas Mackensen , Gloria Lutzny-Geier

The Randomized AMBORA Trial: Impact of Pharmacological/Pharmaceutical Care on Medication Safety and Patient-Reported Outcomes During Treatment With New Oral Anticancer Agents.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Avec: Pauline Dürr , Katja Schlichtig , Carolin Kelz , Birgit Deutsch , Renke Maas , Michael J Eckart , Jochen Wilke , Harald Wagner , Kerstin Wolff , Caroline Preuß , Valeska Brückl , Norbert Meidenbauer , Christian Staerk , Andreas Mayr , Rainer Fietkau , Peter J Goebell , Frank Kunath , Matthias W Beckmann , Andreas Mackensen , Markus F Neurath , Marianne Pavel , Frank Dörje , Martin F Fromm

Influence of DM-sensitivity on immunogenicity of MHC class II restricted antigens.

Journal for immunotherapy of cancer
Avec: Anna Luise Bernhardt , Julia Zeun , Miriam Marecek , Hannah Reimann , Sascha Kretschmann , Judith Bausenwein , Edith D van der Meijden , Margarete M Karg , Tabea Haug , Lisa Meintker , Gloria Lutzny-Geier , Andreas Mackensen , Anita N Kremer

Human CD4

Clinical and experimental immunology
Avec: Johan Verhagen , Edith D van der Meijden , Vanessa Lang , Andreas E Kremer , Simon Völkl , Andreas Mackensen , Michael Aigner , Anita N Kremer

β

Immunity
Avec: Daniel Hofbauer , Dimitrios Mougiakakos , Luca Broggini , Mario Zaiss , Maike Büttner-Herold , Christian Bach , Bernd Spriewald , Frank Neumann , Savita Bisht , Jens Nolting , Robert Zeiser , Shaima'a Hamarsheh , Martin Eberhardt , Julio Vera , Cristina Visentin , Chiara Maria Giulia De Luca , Fabio Moda , Stefan Haskamp , Cindy Flamann , Martin Böttcher , Katrin Bitterer , Simon Völkl , Andreas Mackensen , Stefano Ricagno , Heiko Bruns

Determinants Affecting the Clinical Implementation of a Molecularly Informed Molecular Tumor Board Recommendation: Experience from a Tertiary Cancer Center.

Cancers
Avec: Lars Tögel , Christoph Schubart , Sebastian Lettmaier , Clemens Neufert , Juliane Hoyer , Kerstin Wolff , Evgeny A Moskalev , Robert Stöhr , Abbas Agaimy , André Reis , Bernd Wullich , Andreas Mackensen , Marianne Pavel , Matthias W Beckmann , Arndt Hartmann , Rainer Fietkau , Norbert Meidenbauer , Florian Haller , Silvia Spoerl

Cytokine and reactivity profiles in SLE patients following anti-CD19 CART therapy.

Molecular therapy. Methods & clinical development
Avec: Daniel Nunez , Darshil Patel , Jenell Volkov , Steven Wong , Zachary Vorndran , Fabian Müller , Michael Aigner , Simon Völkl , Andreas Mackensen , Georg Schett , Samik Basu

Reduced cytotoxicity by mutation of lysine 590 of

Immunotherapy advances
Avec: A Ammon , L Mellenthin , C Emmerich , E Naschberger , M Stürzl , A Mackensen , F Müller

Fully human anti-CD19 CAR T cells derived from systemic lupus erythematosus patients exhibit cytotoxicity with reduced inflammatory cytokine production.

Transplantation and cellular therapy
Avec: Janin Dingfelder , Michael Aigner , Jule Taubmann , Ioanna Minopoulou , Soo Park , Charles D Kaplan , Joseph K Cheng , Tom Van Blarcom , Georg Schett , Andreas Mackensen , Gloria Lutzny-Geier

CD19-CAR T-cell therapy induces deep tissue depletion of B cells.

Annals of the rheumatic diseases
Avec: Carlo Tur , Markus Eckstein , Joachim Velden , Simon Rauber , Christina Bergmann , Janina Auth , Laura Bucci , Giulia Corte , Melanie Hagen , Andreas Wirsching , Ricardo Grieshaber-Bouyer , Petra Reis , Nicolai Kittan , Jochen Wacker , Aleix Rius Rigau , Andreas Ramming , Maria-Antonietta D'Agostino , Arndt Hartmann , Fabian Müller , Andreas Mackensen , Aline Bozec , Georg Schett , Maria Gabriella Raimondo

The Oncometabolite 5'-Deoxy-5'-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation.

Frontiers in immunology
Avec: Benedikt Jacobs , Sebastian Schlögl , Carolin Dorothea Strobl , Simon Völkl , Andrej Stoll , Dimitrios Mougiakakos , Karl-Johan Malmberg , Andreas Mackensen , Michael Aigner

Two cases of carfilzomib-induced thrombotic microangiopathy successfully treated with Eculizumab in multiple myeloma.

BMC nephrology
Avec: Michael Rassner , Rebecca Baur , Ralph Wäsch , Mario Schiffer , Johanna Schneider , Andreas Mackensen , Monika Engelhardt

Lymphocyte Immune Response and T Cell Differentiation in Fontan Patients with protein-losing enteropathy.

The Thoracic and cardiovascular surgeon
Avec: Julia Moosmann , Okan Toka , Sören Lukassen , Arif B Ekici , Andreas Mackensen , Simon Völkl , Sven Dittrich

Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease.

Blood
Avec: Yun Zhang , Lichong Shen , Katja Dreißigacker , Honglin Zhu , Thuong Trinh-Minh , Xianyi Meng , Cuong Tran-Manh , Clara Dees , Alexandru-Emil Matei , Chih-Wei Chen , Markus Ditschkowski , Stefan Krauss , Julia Winkler , Daniel Wolff , Mirjana Ziemer , Andreas Beilhack , Sigrid Karrer , Wolfgang Herr , Andreas Mackensen , Georg Schett , Bernd M Spriewald , Jörg H W Distler

Hydrogen-Peroxide Synthesis and LDL-Uptake Controls Immunosuppressive Properties in Monocyte-Derived Dendritic Cells.

Cancers
Avec: Ann-Katrin Menzner , Tanja Rottmar , Simon Voelkl , Jacobus J Bosch , Dimitrios Mougiakakos , Andreas Mackensen , Yazid J Resheq

Human Double-Negative Regulatory T-Cells Induce a Metabolic and Functional Switch in Effector T-Cells by Suppressing mTOR Activity.

Frontiers in immunology
Avec: Tabea Haug , Michael Aigner , Moritz M Peuser , Carolin D Strobl , Kai Hildner , Dimitrios Mougiakakos , Heiko Bruns , Andreas Mackensen , Simon Völkl

Measuring the cellular memory B cell response after vaccination in patients after allogeneic stem cell transplantation.

Annals of hematology
Avec: Julia Winkler , Hannes Tittlbach , Andrea Schneider , Corinna Buchstaller , Andreas Mayr , Ingrid Vasova , Wolf Roesler , Michael Mach , Andreas Mackensen , Thomas H Winkler

CD137 (4-1BB) stimulation leads to metabolic and functional reprogramming of human monocytes/macrophages enhancing their tumoricidal activity.

Leukemia
Avec: A Stoll , H Bruns , M Fuchs , S Völkl , F Nimmerjahn , M Kunz , M Peipp , A Mackensen , D Mougiakakos

Arming Immune Cells for Battle: A Brief Journey through the Advancements of T and NK Cell Immunotherapy.

Cancers
Avec: Philipp Wendel , Lisa Marie Reindl , Tobias Bexte , Leander Künnemeyer , Vinzenz Särchen , Nawid Albinger , Andreas Mackensen , Eva Rettinger , Tobias Bopp , Evelyn Ullrich

Successful treatment of COVID-19 infection with convalescent plasma in B-cell-depleted patients may promote cellular immunity.

European journal of immunology
Avec: Andreas E Kremer , Anita N Kremer , Carsten Willam , Simon Völkl , Johan Verhagen , Susanne Achenbach , Edith D van der Meijden , Vanessa Lang , Michael Aigner , Clara Maier , Matthias Tenbusch , Klaus Korn , Gloria Lutzny-Geier , Silvia Spoerl , Richard Strauß , Marcel Vetter , Klaus Überla , Markus F Neurath , Andreas Mackensen , Mario Schiffer , Holger Hackstein

Bone marrow stroma cells promote induction of a chemoresistant and prognostic unfavorable S100A8/A9high AML cell subset.

Blood advances
Avec: Martin Böttcher , Konstantinos Panagiotidis , Heiko Bruns , Martina Stumpf , Simon Völkl , Stefanie Geyh , Barbara Dietel , Thomas Schroeder , Andreas Mackensen , Dimitrios Mougiakakos

The metabolic profile of reconstituting T-cells, NK-cells, and monocytes following autologous stem cell transplantation and its impact on outcome.

Scientific reports
Avec: Silja Richter , Martin Böttcher , Simon Völkl , Andreas Mackensen , Evelyn Ullrich , Benedikt Jacobs , Dimitrios Mougiakakos

Reconstitution of EBV-directed T cell immunity by adoptive transfer of peptide-stimulated T cells in a patient after allogeneic stem cell transplantation for AITL.

PLoS pathogens
Avec: María Fernanda Lammoglia Cobo , Julia Ritter , Regina Gary , Volkhard Seitz , Josef Mautner , Michael Aigner , Simon Völkl , Stefanie Schaffer , Stephanie Moi , Anke Seegebarth , Heiko Bruns , Wolf Rösler , Kerstin Amann , Maike Büttner-Herold , Steffen Hennig , Andreas Mackensen , Michael Hummel , Andreas Moosmann , Armin Gerbitz

Increased PD-1 expression on circulating T-cells correlates with inferior outcome after autologous stem cell transplantation.

Transplantation and cellular therapy
Avec: Silja Richter , Martin Böttcher , Andrej Stoll , Vanja Zeremski , Simon Völkl , Andreas Mackensen , Arif B Ekici , Benedikt Jacobs , Dimitrios Mougiakakos

Successful Generation of CD19 Chimeric Antigen Receptor T Cells from Patients with Advanced Systemic Lupus Erythematosus.

Transplantation and cellular therapy
Avec: S Kretschmann , S Völkl , H Reimann , G Krönke , G Schett , S Achenbach , G Lutzny-Geier , F Müller , D Mougiakakos , J Dingfelder , C Flamann , L Hanssens , R Gary , A Mackensen , M Aigner

New Oral Antitumor Drugs and Medication Safety in Uro-Oncology: Implications for Clinical Practice Based on a Subgroup Analysis of the AMBORA Trial.

Journal of clinical medicine
Avec: Katja Schlichtig , Lisa Cuba , Pauline Dürr , Laura Bellut , Norbert Meidenbauer , Frank Kunath , Peter J Goebell , Andreas Mackensen , Frank Dörje , Martin F Fromm , Bernd Wullich

Accumulation of T-cell-suppressive PD-L1

Journal for immunotherapy of cancer
Avec: Rebecca Baur , Franziska Karl , Romy Böttcher-Loschinski , Andrej Stoll , Simon Völkl , Andreas Gießl , Cindy Flamann , Heiko Bruns , Ursula Schlötzer-Schrehardt , Martin Böttcher , Denis M Schewe , Thomas Fischer , Regina Jitschin , Andreas Mackensen , Dimitrios Mougiakakos

Targeted inhibition of protein synthesis renders cancer cells vulnerable to apoptosis by unfolded protein response.

Cell death & disease
Avec: Franziska Gsottberger , Christina Meier , Anna Ammon , Scott Parker , Kerstin Wendland , Rebekka George , Srdjan Petkovic , Lisa Mellenthin , Charlotte Emmerich , Gloria Lutzny-Geier , Markus Metzler , Andreas Mackensen , Vidyalakshmi Chandramohan , Fabian Müller

CLDN6-specific CAR-T cells plus amplifying RNA vaccine in relapsed or refractory solid tumors: the phase 1 BNT211-01 trial.

Nature medicine
Avec: Andreas Mackensen , John B A G Haanen , Christian Koenecke , Winfried Alsdorf , Eva Wagner-Drouet , Peter Borchmann , Daniel Heudobler , Barbara Ferstl , Sebastian Klobuch , Carsten Bokemeyer , Alexander Desuki , Florian Lüke , Nadine Kutsch , Fabian Müller , Eveline Smit , Peter Hillemanns , Panagiotis Karagiannis , Erol Wiegert , Ying He , Thang Ho , Qing Kang-Fortner , Anna Melissa Schlitter , Catrine Schulz-Eying , Andrew Finlayson , Carina Flemmig , Klaus Kühlcke , Liane Preußner , Benjamin Rengstl , Özlem Türeci , Uğur Şahin

Réseau de co-auteurs

Simon Völkl 30 collaborations
Dimitrios Mougiakakos 26 collaborations
Michael Aigner 16 collaborations
Fabian Müller 14 collaborations
Georg Schett 12 collaborations
Heiko Bruns 11 collaborations
Martin Böttcher 10 collaborations
Anita N Kremer 10 collaborations
Sascha Kretschmann 7 collaborations
Gloria Lutzny-Geier 7 collaborations
Andrej Stoll 7 collaborations
Arndt Hartmann 6 collaborations
Matthias W Beckmann 6 collaborations
Maike Büttner-Herold 6 collaborations
Marion Subklewe 5 collaborations
Norbert Meidenbauer 5 collaborations
Silvia Spoerl 5 collaborations
Soraya Kharboutli 5 collaborations
A Mackensen 5 collaborations
Jule Taubmann 5 collaborations
Hannah Reimann 5 collaborations
Ricardo Grieshaber-Bouyer 5 collaborations
Edith D van der Meijden 5 collaborations
Rebecca Baur 5 collaborations
Regina Jitschin 4 collaborations
Kai Rejeski 4 collaborations
Ariel Perez 4 collaborations
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Michael von Bergwelt-Baildon 4 collaborations
Michael D Jain 4 collaborations
Hermann Einsele 4 collaborations
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