Andrew Filer

Affiliations
  • Rheumatology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Queen Elizabeth Hospital, Birmingham, B15 2WB, UK.
  • Sandwell and West Birmingham Hospitals NHS Trust, West Bromwich, West Midlands, B71 4HJ, UK.

Publications (53)

Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol.

Trials
Avec: Mariam Al-Laith , Marianna Jasenecova , Sonya Abraham , Aisla Bosworth , Ian N Bruce , Christopher D Buckley , Coziana Ciurtin , Maria-Antonietta D'Agostino , Paul Emery , Hill Gaston , John D Isaacs , Andrew Filer , Benjamin A Fisher , Thomas W J Huizinga , Pauline Ho , Clare Jacklin , Heidi Lempp , Iain B McInnes , Arthur G Pratt , Andrew Östor , Karim Raza , Peter C Taylor , Dirkjan van Schaardenburg , Dharshene Shivapatham , Alison J Wright , Joana C Vasconcelos , Joanna Kelly , Caroline Murphy , A Toby Prevost , Andrew P Cope

Attitudes towards Oral Health in Patients with Rheumatoid Arthritis: A Qualitative Study Nested within a Randomized Controlled Trial.

JDR clinical and translational research
Avec: S Serban , T Dietrich , I Lopez-Oliva , P de Pablo , K Raza , A Filer , I L C Chapple , K Hill

Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?

Annals of the rheumatic diseases
Avec: Susan R Aungier , Alison J Cartwright , Anja Schwenzer , Jennifer L Marshall , Michael R Dyson , Peter Slavny , Kothai Parthiban , Aneesh Karatt-Vellatt , Ilfita Sahbudin , Eric Culbert , Patrick Hextall , Felix Il Clanchy , Richard Williams , Brian D Marsden , Karim Raza , Andrew Filer , Christopher Dominic Buckley , John McCafferty , Kim S Midwood

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis.

Nature communications
Avec: Trinidad Montero-Melendez , Ai Nagano , Claude Chelala , Andrew Filer , Christopher D Buckley , Mauro Perretti

Global Deletion of 11β-HSD1 Prevents Muscle Wasting Associated with Glucocorticoid Therapy in Polyarthritis.

International journal of molecular sciences
Avec: Justine M Webster , Michael S Sagmeister , Chloe G Fenton , Alex P Seabright , Yu-Chiang Lai , Simon W Jones , Andrew Filer , Mark S Cooper , Gareth G Lavery , Karim Raza , Ramon Langen , Rowan S Hardy

Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases.

Med (New York, N.Y.)
Avec: Ilya Korsunsky , Kevin Wei , Mathilde Pohin , Edy Y Kim , Francesca Barone , Triin Major , Emily Taylor , Rahul Ravindran , Samuel Kemble , Gerald F M Watts , A Helena Jonsson , Yunju Jeong , Humra Athar , Dylan Windell , Joyce B Kang , Matthias Friedrich , Jason Turner , Saba Nayar , Benjamin A Fisher , Karim Raza , Jennifer L Marshall , Adam P Croft , Tomoyoshi Tamura , Lynette M Sholl , Marina Vivero , Ivan O Rosas , Simon J Bowman , Mark Coles , Andreas P Frei , Kara Lassen , Andrew Filer , Fiona Powrie , Christopher D Buckley , Michael B Brenner , Soumya Raychaudhuri

The value of ultrasound-defined tenosynovitis and synovitis in the prediction of persistent arthritis.

Rheumatology (Oxford, England)
Avec: Ilfita Sahbudin , Ruchir Singh , Paola De Pablo , Elizabeth Rankin , Benjamin Rhodes , Elizabeth Justice , Emma Derrett-Smith , Nicole Amft , Nehal Narayan , Catherine McGrath , Sangeetha Baskar , Jeanette Trickey , Mark Maybury , Karim Raza , Andrew Filer

Outcomes of periodontal therapy in rheumatoid arthritis: The OPERA feasibility randomized trial.

Journal of clinical periodontology
Avec: Paola de Pablo , Stefan Serban , Isabel Lopez-Oliva , Joanna Rooney , Kirsty Hill , Karim Raza , Andrew Filer , Iain Chapple , Thomas Dietrich

Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium.

bioRxiv : the preprint server for biology
Avec: Garrett Dunlap , Aaron Wagner , Nida Meednu , Fan Zhang , A Helena Jonsson , Kevin Wei , Saori Sakaue , Aparna Nathan , Auteur inconnu , Vivian P Bykerk , Laura T Donlin , Susan M Goodman , Gary S Firestein , David L Boyle , V Michael Holers , Larry W Moreland , Darren Tabechian , Costantino Pitzalis , Andrew Filer , Soumya Raychaudhuri , Michael B Brenner , Andrew McDavid , Deepak A Rao , Jennifer H Anolik

Is symptom duration before DMARD therapy a determinant of direct and indirect costs in DMARD-naïve RA patients? A systematic review.

Rheumatology advances in practice
Avec: Ilfita Sahbudin , Ruchir Singh , Jeanette Trickey , Aliaksandra Baranskaya , Alexander Tracy , Karim Raza , Andrew Filer , Sue Jowett , Annelies Boonen

Notch signalling drives synovial fibroblast identity and arthritis pathology.

Nature
Avec: Kevin Wei , Ilya Korsunsky , Jennifer L Marshall , Anqi Gao , Gerald F M Watts , Triin Major , Adam P Croft , Jordan Watts , Philip E Blazar , Jeffrey K Lange , Thomas S Thornhill , Andrew Filer , Karim Raza , Laura T Donlin , Auteur inconnu , Christian W Siebel , Christopher D Buckley , Soumya Raychaudhuri , Michael B Brenner

New Developments in Transcriptomic Analysis of Synovial Tissue.

Frontiers in medicine
Avec: Hayley L Carr , Jason D Turner , Triin Major , Dagmar Scheel-Toellner , Andrew Filer

Distinct fibroblast subsets drive inflammation and damage in arthritis.

Nature
Avec: Adam P Croft , Joana Campos , Kathrin Jansen , Jason D Turner , Jennifer Marshall , Moustafa Attar , Loriane Savary , Corinna Wehmeyer , Amy J Naylor , Samuel Kemble , Jenefa Begum , Kerstin Dürholz , Harris Perlman , Francesca Barone , Helen M McGettrick , Douglas T Fearon , Kevin Wei , Soumya Raychaudhuri , Ilya Korsunsky , Michael B Brenner , Mark Coles , Stephen N Sansom , Andrew Filer , Christopher D Buckley

Detecting inflammation in rheumatoid arthritis using Fourier transform analysis of dorsal optical transmission images from a pilot study.

Journal of biomedical optics
Avec: Daniel Lighter , Andrew Filer , Hamid Dehghani

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.

Immunity
Avec: Jasna Friščić , Martin Böttcher , Christiane Reinwald , Heiko Bruns , Benjamin Wirth , Samantha-Josefine Popp , Kellie Irene Walker , Jochen A Ackermann , Xi Chen , Jason Turner , Honglin Zhu , Lisa Seyler , Maximilien Euler , Philipp Kirchner , René Krüger , Arif B Ekici , Triin Major , Oliver Aust , Daniela Weidner , Anita Fischer , Fabian T Andes , Zeljka Stanojevic , Vladimir Trajkovic , Martin Herrmann , Adelheid Korb-Pap , Isabel Wank , Andreas Hess , Johnathan Winter , Viktor Wixler , Jörg Distler , Günter Steiner , Hans P Kiener , Benjamin Frey , Lasse Kling , Karim Raza , Silke Frey , Arnd Kleyer , Tobias Bäuerle , Timothy R Hughes , Anika Grüneboom , Ulrike Steffen , Gerhard Krönke , Adam P Croft , Andrew Filer , Jörg Köhl , Kerstin Klein , Christopher D Buckley , Georg Schett , Dimitrios Mougiakakos , Markus H Hoffmann

Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC).

Annals of the rheumatic diseases
Avec: Gloria Lliso-Ribera , Frances Humby , Myles Lewis , Alessandra Nerviani , Daniele Mauro , Felice Rivellese , Stephen Kelly , Rebecca Hands , Fabiola Bene , Nandhini Ramamoorthi , Jason A Hackney , Alberto Cauli , Ernest H Choy , Andrew Filer , Peter C Taylor , Iain McInnes , Michael J Townsend , Costantino Pitzalis

Very low prevalence of ultrasound-detected tenosynovial abnormalities in healthy subjects throughout the age range: OMERACT ultrasound minimal disease study.

Annals of the rheumatic diseases
Avec: Jeanette Trickey , Ilfita Sahbudin , Mads Ammitzbøll-Danielsen , Irene Azzolin , Carina Borst , Alessandra Bortoluzzi , George Aw Bruyn , Philippe Carron , Coziana Ciurtin , Georgios Filippou , Jacek Fliciński , Daniela Fodor , Hélène Gouze , Marwin Gutierrez , Hilde Berner Hammer , Ellen-Margrethe Hauge , Annamaria Iagnocco , Kei Ikeda , Rositsa Karalilova , Helen Isobel Keen , Marion Kortekaas , Giuliana La Paglia , Gustavo Leon , Peter Mandl , Mihaela Maruseac , Marcin Milchert , Mohamed Atia Mortada , Esperanza Naredo , Sarah Ohrndorf , Carlos Pineda , Mads Nyhuus Bendix Rasch , Cristina Reátegui-Sokolova , Garifallia Sakellariou , Teodora Serban , Cesar A Sifuentes-Cantú , Maria S Stoenoiu , Takeshi Suzuki , Lene Terslev , Ilaria Tinazzi , Florentin Ananu Vreju , Ruth Wittoek , Maria-Antonietta D'Agostino , Andrew Filer

Tissue-resident, extravascular Ly6c

Cell reports
Avec: Anna B Montgomery , Shang Yang Chen , Yidan Wang , Gaurav Gadhvi , Maximilian G Mayr , Carla M Cuda , Salina Dominguez , Hadijat-Kubura Moradeke Makinde , Miranda G Gurra , Alexander V Misharin , Arthur M Mandelin , Eric M Ruderman , Anjali Thakrar , Simran Brar , Mary Carns , Kathleen Aren , Mahzad Akbarpour , Andrew Filer , Saba Nayar , Ana Teososio , Triin Major , Ankit Bharat , G R Scott Budinger , Deborah R Winter , Harris Perlman

New biologic (Ab-IPL-IL-17) for IL-17-mediated diseases: identification of the bioactive sequence (nIL-17) for IL-17A/F function.

Annals of the rheumatic diseases
Avec: Anella Saviano , Adel Abo Manosour , Federica Raucci , Francesco Merlino , Noemi Marigliano , Anna Schettino , Mussarat Wahid , Jenefa Begum , Andrew Filer , Julia E Manning , Gian Marco Casillo , Marialuisa Piccolo , Maria Grazia Ferraro , Simona Marzano , Pasquale Russomanno , Rosa Bellavita , Carlo Irace , Jussara Amato , Mohammed Alfaifi , Peter Rimmer , Tariq Iqbal , Stefano Pieretti , Valentina Vellecco , Francesco Caso , Luisa Costa , Roberto Giacomelli , Raffaele Scarpa , Giuseppe Cirino , Mariarosaria Bucci , Helen M McGettrick , Paolo Grieco , Asif Jilani Iqbal , Francesco Maione

Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.

Science translational medicine
Avec: Kelsey N Thompson , Kevin S Bonham , Nicholas E Ilott , Graham J Britton , Paula Colmenero , Samuel J Bullers , Lauren J McIver , Siyuan Ma , Long H Nguyen , Andrew Filer , India Brough , Claire Pearson , Caroline Moussa , Vinod Kumar , Lilian H Lam , Matthew A Jackson , April Pawluk , Auteur inconnu , Serafim Kiriakidis , Peter C Taylor , Lucy R Wedderburn , Brian Marsden , Stephen P Young , Dan R Littman , Jeremiah J Faith , Arthur G Pratt , Paul Bowness , Karim Raza , Fiona Powrie , Curtis Huttenhower , Auteur inconnu

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis.

Nature medicine
Avec: Stefano Alivernini , Lucy MacDonald , Aziza Elmesmari , Samuel Finlay , Barbara Tolusso , Maria Rita Gigante , Luca Petricca , Clara Di Mario , Laura Bui , Simone Perniola , Moustafa Attar , Marco Gessi , Anna Laura Fedele , Sabarinadh Chilaka , Domenico Somma , Stephen N Sansom , Andrew Filer , Charles McSharry , Neal L Millar , Kristina Kirschner , Alessandra Nerviani , Myles J Lewis , Costantino Pitzalis , Andrew R Clark , Gianfranco Ferraccioli , Irina Udalova , Christopher D Buckley , Elisa Gremese , Iain B McInnes , Thomas D Otto , Mariola Kurowska-Stolarska

Vitamin D and early rheumatoid arthritis.

BMC rheumatology
Avec: Stephanie R Harrison , Gurpreet Jutley , Danyang Li , Ilfita Sahbudin , Andrew Filer , Martin Hewison , Karim Raza

Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Saba Nayar , Joana Campos , Charlotte G Smith , Valentina Iannizzotto , David H Gardner , Frédéric Mourcin , David Roulois , Jason Turner , Marvin Sylvestre , Saba Asam , Bridget Glaysher , Simon J Bowman , Douglas T Fearon , Andrew Filer , Karin Tarte , Sanjiv A Luther , Benjamin A Fisher , Christopher D Buckley , Mark C Coles , Francesca Barone

Type 2 diabetes mellitus, glycaemic control, associated therapies and risk of rheumatoid arthritis: a retrospective cohort study.

Rheumatology (Oxford, England)
Avec: Dawit T Zemedikun , Krishna Gokhale , Joht Singh Chandan , Jennifer Cooper , Janet M Lord , Andrew Filer , Marie Falahee , Krishnarajah Nirantharakumar , Karim Raza

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis.

Nature communications
Avec: Frank Penkava , Martin Del Castillo Velasco-Herrera , Matthew D Young , Nicole Yager , Lilian N Nwosu , Arthur G Pratt , Alicia Lledo Lara , Charlotte Guzzo , Ash Maroof , Lira Mamanova , Suzanne Cole , Mirjana Efremova , Davide Simone , Andrew Filer , Chrysothemis C Brown , Andrew L Croxford , John D Isaacs , Sarah Teichmann , Paul Bowness , Sam Behjati , M Hussein Al-Mossawi

BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study.

BMC rheumatology
Avec: Fiona Rayner , Amy E Anderson , Kenneth F Baker , Christopher D Buckley , Bernard Dyke , Sally Fenton , Andrew Filer , Carl S Goodyear , Catharien M U Hilkens , Shaun Hiu , Sean Kerrigan , Mariola Kurowska-Stolarska , Fiona Matthews , Iain McInnes , Wan-Fai Ng , Arthur G Pratt , Jonathan Prichard , Karim Raza , Stefan Siebert , Deborah Stocken , M Dawn Teare , Stephen Young , John D Isaacs

EULAR points to consider for minimal reporting requirements in synovial tissue research in rheumatology.

Annals of the rheumatic diseases
Avec: Aurélie Najm , Félicie Costantino , Stefano Alivernini , Alessia Alunno , Elettra Bianchi , Jacqueline Bignall , Brendan Boyce , Juan D Cañete , Francesco Carubbi , Patrick Durez , João Eurico Fonseca , Søren Andreas Just , Raquel Largo , Antonio Manzo , Mark Maybury , Esperanza Naredo , Carl Orr , Costantino Pitzalis , Felice Rivellese , Vasco C Romão , Jef van Rompay , Sander W Tas , Douglas J Veale , Maria-Antonietta D'Agostino , Andrew Filer

Number of days required to measure sedentary time and physical activity using accelerometery in rheumatoid arthritis: a reliability study.

Rheumatology international
Avec: Ciara M O'Brien , George D Kitas , Fiona Rayner , John D Isaacs , Kenneth F Baker , Arthur G Pratt , Christopher D Buckley , Karim Raza , Andrew Filer , Stefan Siebert , Iain McInnes , Andrew McGucken , Sally A M Fenton , Auteur inconnu

Differential effect of lactate on synovial fibroblast and macrophage effector functions.

Frontiers in immunology
Avec: Valentina Pucino , Meriam Nefla , Vincent Gauthier , Ghada Alsaleh , Sally A Clayton , Jennifer Marshall , Andrew Filer , Andy R Clark , Karim Raza , Christopher D Buckley

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis.

bioRxiv : the preprint server for biology
Avec: Jun Inamo , Joshua Keegan , Alec Griffith , Tusharkanti Ghosh , Alice Horisberger , Kaitlyn Howard , John Pulford , Ekaterina Murzin , Brandon Hancock , Anna Helena Jonsson , Jennifer Seifert , Marie L Feser , Jill M Norris , Ye Cao , William Apruzzese , S Louis Bridges , Vivian Bykerk , Susan Goodman , Laura Donlin , Gary S Firestein , Harris Perlman , Joan M Bathon , Laura B Hughes , Darren Tabechian , Andrew Filer , Costantino Pitzalis , Jennifer H Anolik , Larry Moreland , Joel M Guthridge , Judith A James , Michael B Brenner , Soumya Raychaudhuri , Jeffrey A Sparks , Auteur inconnu , V Michael Holers , Kevin D Deane , James A Lederer , Deepak A Rao , Fan Zhang

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.

Nature immunology
Avec: Fan Zhang , Kevin Wei , Kamil Slowikowski , Chamith Y Fonseka , Deepak A Rao , Stephen Kelly , Susan M Goodman , Darren Tabechian , Laura B Hughes , Karen Salomon-Escoto , Gerald F M Watts , A Helena Jonsson , Javier Rangel-Moreno , Nida Meednu , Cristina Rozo , William Apruzzese , Thomas M Eisenhaure , David J Lieb , David L Boyle , Arthur M Mandelin , Auteur inconnu , Brendan F Boyce , Edward DiCarlo , Ellen M Gravallese , Peter K Gregersen , Larry Moreland , Gary S Firestein , Nir Hacohen , Chad Nusbaum , James A Lederer , Harris Perlman , Costantino Pitzalis , Andrew Filer , V Michael Holers , Vivian P Bykerk , Laura T Donlin , Jennifer H Anolik , Michael B Brenner , Soumya Raychaudhuri

Spontaneously Resolving Joint Inflammation Is Characterised by Metabolic Agility of Fibroblast-Like Synoviocytes.

Frontiers in immunology
Avec: Jane Falconer , Valentina Pucino , Sally A Clayton , Jennifer L Marshall , Sabrina Raizada , Holly Adams , Andrew Philp , Andrew R Clark , Andrew Filer , Karim Raza , Stephen P Young , Christopher D Buckley

Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial.

The Lancet. Rheumatology
Avec: Arthur G Pratt , Stefan Siebert , Michael Cole , Deborah D Stocken , Christina Yap , Stephen Kelly , Muddassir Shaikh , Amy Cranston , Miranda Morton , Jenn Walker , Sheelagh Frame , Wan-Fai Ng , Christopher D Buckley , Iain B McInnes , Andrew Filer , John D Isaacs

TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis.

Trials
Avec: M Cole , C Yap , C Buckley , W F Ng , I McInnes , A Filer , S Siebert , A Pratt , J D Isaacs , D D Stocken

Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial.

Lancet (London, England)
Avec: Andrew P Cope , Marianna Jasenecova , Joana C Vasconcelos , Andrew Filer , Karim Raza , Sumera Qureshi , Maria Antonietta D'Agostino , Iain B McInnes , John D Isaacs , Arthur G Pratt , Benjamin A Fisher , Christopher D Buckley , Paul Emery , Pauline Ho , Maya H Buch , Coziana Ciurtin , Dirkjan van Schaardenburg , Thomas Huizinga , René Toes , Evangelos Georgiou , Joanna Kelly , Caroline Murphy , A Toby Prevost , Auteur inconnu

LAT1 enables T cell activation under inflammatory conditions.

Journal of autoimmunity
Avec: Joy Ogbechi , Helen L Wright , Stefan Balint , Louise M Topping , Zec Kristina , Yi-Shu Huang , Eirini Pantazi , Maarten Swart , Dylan Windell , Eros Marin , Michael F Wempe , Hitoshi Endou , Andrew M Thomas , Andrew Filer , Trevor W Stone , Alexander J Clarke , Michael L Dustin , Richard O Williams

Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue.

Nature communications
Avec: Richard D Bell , Matthew Brendel , Maxwell A Konnaris , Justin Xiang , Miguel Otero , Mark A Fontana , Zilong Bai , Auteur inconnu , Daria M Krenitsky , Nida Meednu , Javier Rangel-Moreno , Dagmar Scheel-Toellner , Hayley Carr , Saba Nayar , Jack McMurray , Edward DiCarlo , Jennifer H Anolik , Laura T Donlin , Dana E Orange , H Mark Kenney , Edward M Schwarz , Andrew Filer , Lionel B Ivashkiv , Fei Wang

Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium.

Nature communications
Avec: Garrett Dunlap , Aaron Wagner , Nida Meednu , Ruoqiao Wang , Fan Zhang , Jabea Cyril Ekabe , Anna Helena Jonsson , Kevin Wei , Saori Sakaue , Aparna Nathan , Auteur inconnu , Vivian P Bykerk , Laura T Donlin , Susan M Goodman , Gary S Firestein , David L Boyle , V Michael Holers , Larry W Moreland , Darren Tabechian , Costantino Pitzalis , Andrew Filer , Soumya Raychaudhuri , Michael B Brenner , Juilee Thakar , Andrew McDavid , Deepak A Rao , Jennifer H Anolik

Targeting the rheumatoid arthritis synovial fibroblast via cyclin dependent kinase inhibition: An early phase trial.

Medicine
Avec: Stefan Siebert , Arthur G Pratt , Deborah D Stocken , Miranda Morton , Amy Cranston , Michael Cole , Sheelagh Frame , Christopher D Buckley , Wan-Fai Ng , Andrew Filer , Iain B McInnes , John D Isaacs

Skeletal muscle dysregulation in rheumatoid arthritis: Metabolic and molecular markers in a rodent model and patients.

PloS one
Avec: Nuria Casanova-Vallve , Dumitru Constantin-Teodosiu , Andrew Filer , Rowan S Hardy , Paul L Greenhaff , Victoria Chapman

Bilateral Anterior Thigh Thickness: A New Diagnostic Tool for the Identification of Low Muscle Mass?

Journal of the American Medical Directors Association
Avec: Daisy V Wilson , Hannah Moorey , Howard Stringer , Ilfita Sahbudin , Andrew Filer , Janet M Lord , Elizabeth Sapey

Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability.

Genome biology
Avec: Xiangyu Ge , Mojca Frank-Bertoncelj , Kerstin Klein , Amanda McGovern , Tadeja Kuret , Miranda Houtman , Blaž Burja , Raphael Micheroli , Chenfu Shi , Miriam Marks , Andrew Filer , Christopher D Buckley , Gisela Orozco , Oliver Distler , Andrew P Morris , Paul Martin , Stephen Eyre , Caroline Ospelt

Relationship Between Inflammation and Metabolism in Patients With Newly Presenting Rheumatoid Arthritis.

Frontiers in immunology
Avec: Gurpreet Singh Jutley , Kalvin Sahota , Ilfita Sahbudin , Andrew Filer , Thurayya Arayssi , Stephen P Young , Karim Raza

Systematic review of imaging tests to predict the development of rheumatoid arthritis in people with unclassified arthritis.

Seminars in arthritis and rheumatism
Avec: Paola de Pablo , Jacqueline Dinnes , Sarah Berhane , Aya Osman , Zhia Lim , April Coombe , Karim Raza , Andrew Filer , Jonathan J Deeks

Evaluation of the mechanisms of sarcopenia in chronic inflammatory disease: protocol for a prospective cohort study.

Skeletal muscle
Avec: Amritpal Dhaliwal , Felicity R Williams , Jonathan I Quinlan , Sophie L Allen , Carolyn Greig , Andrew Filer , Karim Raza , Subrata Ghosh , Gareth G Lavery , Philip N Newsome , Surabhi Choudhary , Leigh Breen , Matthew J Armstrong , Ahmed M Elsharkawy , Janet M Lord

Inflammation causes remodeling of mitochondrial cytochrome

Science advances
Avec: Sally A Clayton , Kalbinder K Daley , Lucy MacDonald , Erika Fernandez-Vizarra , Giovanni Bottegoni , John D O'Neil , Triin Major , Daniel Griffin , Qinqin Zhuang , Adeolu B Adewoye , Kieran Woolcock , Simon W Jones , Carl Goodyear , Aziza Elmesmari , Andrew Filer , Daniel A Tennant , Stefano Alivernini , Christopher D Buckley , Robert D S Pitceathly , Mariola Kurowska-Stolarska , Andrew R Clark

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis.

Nature communications
Avec: Yilin Wang , Aneesah Khan , Aristotelis Antonopoulos , Laura Bouché , Christopher D Buckley , Andrew Filer , Karim Raza , Kun-Ping Li , Barbara Tolusso , Elisa Gremese , Mariola Kurowska-Stolarska , Stefano Alivernini , Anne Dell , Stuart M Haslam , Miguel A Pineda

Assessing acoustic competition between sibling frog species using rhythm analysis.

Ecology and evolution
Avec: Alannah Filer , Lara S Burchardt , Berndt J van Rensburg

Impact of synovial biopsy procedures and disease-specific aspects on synovial tissue outcome: a systematic literature review informing the EULAR points to consider for the minimal reporting requirements in synovial tissue research in rheumatology.

RMD open
Avec: Aurélie Najm , Félicie Costantino , Catherine Weill , Andrew Filer , Maria Antonieta D'Agostino

The Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: predicting clinical arthritis development.

Scandinavian journal of rheumatology
Avec: L van Boheemen , M M Ter Wee , M Falahee , A Filer , M van Beers-Tas , A Finckh , A Hensvold , K Raza , D van Schaardenburg

11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation.

International journal of molecular sciences
Avec: Chloe G Fenton , Ana Crastin , Claire S Martin , Saicharan Suresh , Isabella Montagna , Bismah Hussain , Amy J Naylor , Simon W Jones , Morten S Hansen , Caroline M Gorvin , Maria Price , Andrew Filer , Mark S Cooper , Gareth G Lavery , Karim Raza , Rowan S Hardy

Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.

Nature
Avec: Fan Zhang , Anna Helena Jonsson , Aparna Nathan , Nghia Millard , Michelle Curtis , Qian Xiao , Maria Gutierrez-Arcelus , William Apruzzese , Gerald F M Watts , Dana Weisenfeld , Saba Nayar , Javier Rangel-Moreno , Nida Meednu , Kathryne E Marks , Ian Mantel , Joyce B Kang , Laurie Rumker , Joseph Mears , Kamil Slowikowski , Kathryn Weinand , Dana E Orange , Laura Geraldino-Pardilla , Kevin D Deane , Darren Tabechian , Arnoldas Ceponis , Gary S Firestein , Mark Maybury , Ilfita Sahbudin , Ami Ben-Artzi , Arthur M Mandelin , Alessandra Nerviani , Myles J Lewis , Felice Rivellese , Costantino Pitzalis , Laura B Hughes , Diane Horowitz , Edward DiCarlo , Ellen M Gravallese , Brendan F Boyce , Auteur inconnu , Larry W Moreland , Susan M Goodman , Harris Perlman , V Michael Holers , Katherine P Liao , Andrew Filer , Vivian P Bykerk , Kevin Wei , Deepak A Rao , Laura T Donlin , Jennifer H Anolik , Michael B Brenner , Soumya Raychaudhuri

Associations between rheumatoid arthritis clinical factors with synovial cell types and states.

Arthritis & rheumatology (Hoboken, N.J.)
Avec: Dana Weisenfeld , Fan Zhang , Laura Donlin , Anna Helena Jonsson , William Apruzzese , Debbie Campbell , Auteur inconnu , Deepak A Rao , Kevin Wei , V Michael Holers , Ellen Gravallese , Larry Moreland , Susan Goodman , Michael Brenner , Soumya Raychaudhuri , Andrew Filer , Jennifer Anolik , Vivian Bykerk , Katherine P Liao

Réseau de co-auteurs

Karim Raza 22 collaborations
Christopher D Buckley 18 collaborations
None None 12 collaborations
Soumya Raychaudhuri 9 collaborations
Arthur G Pratt 8 collaborations
Ilfita Sahbudin 8 collaborations
Kevin Wei 8 collaborations
Michael B Brenner 8 collaborations
Costantino Pitzalis 8 collaborations
John D Isaacs 7 collaborations
Triin Major 6 collaborations
Fan Zhang 6 collaborations
Laura T Donlin 6 collaborations
V Michael Holers 6 collaborations
Deepak A Rao 6 collaborations
Jennifer H Anolik 6 collaborations
Iain B McInnes 5 collaborations
Saba Nayar 5 collaborations
Nida Meednu 5 collaborations
Gary S Firestein 5 collaborations
Darren Tabechian 5 collaborations
Harris Perlman 5 collaborations
Benjamin A Fisher 4 collaborations
Jennifer L Marshall 4 collaborations
Gerald F M Watts 4 collaborations
Adam P Croft 4 collaborations
Vivian P Bykerk 4 collaborations
Susan M Goodman 4 collaborations
Stefano Alivernini 4 collaborations
Mariola Kurowska-Stolarska 4 collaborations
Stefan Siebert 4 collaborations
Anna Helena Jonsson 4 collaborations
William Apruzzese 4 collaborations
Coziana Ciurtin 3 collaborations
Maria-Antonietta D'Agostino 3 collaborations
Peter C Taylor 3 collaborations
A Filer 3 collaborations
Simon W Jones 3 collaborations
Gareth G Lavery 3 collaborations
Rowan S Hardy 3 collaborations
Ilya Korsunsky 3 collaborations
Francesca Barone 3 collaborations
A Helena Jonsson 3 collaborations
Jason Turner 3 collaborations
Jeanette Trickey 3 collaborations
Mark Maybury 3 collaborations
Aparna Nathan 3 collaborations
David L Boyle 3 collaborations
Larry W Moreland 3 collaborations
Alessandra Nerviani 3 collaborations
Felice Rivellese 3 collaborations
Stephen Kelly 3 collaborations
Iain McInnes 3 collaborations
Arthur M Mandelin 3 collaborations
Stephen P Young 3 collaborations
Andrew R Clark 3 collaborations
Janet M Lord 3 collaborations
Wan-Fai Ng 3 collaborations
Sally A Clayton 3 collaborations
Laura B Hughes 3 collaborations
Larry Moreland 3 collaborations
Javier Rangel-Moreno 3 collaborations
Edward DiCarlo 3 collaborations
Marianna Jasenecova 2 collaborations
Paul Emery 2 collaborations
Pauline Ho 2 collaborations
Dirkjan van Schaardenburg 2 collaborations
Joana C Vasconcelos 2 collaborations
Joanna Kelly 2 collaborations
Caroline Murphy 2 collaborations
A Toby Prevost 2 collaborations
Andrew P Cope 2 collaborations
K Raza 2 collaborations
Chloe G Fenton 2 collaborations
Mark S Cooper 2 collaborations
Samuel Kemble 2 collaborations
Dylan Windell 2 collaborations
Joyce B Kang 2 collaborations
Simon J Bowman 2 collaborations
Mark Coles 2 collaborations
Fiona Powrie 2 collaborations
Ruchir Singh 2 collaborations
Paola de Pablo 2 collaborations
Garrett Dunlap 2 collaborations
Aaron Wagner 2 collaborations
Saori Sakaue 2 collaborations
Andrew McDavid 2 collaborations
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