Margo Tuerlings

Affiliations

Leiden University Medical Center, Leiden, The Netherlands.

Publications (16)

RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.

Arthritis & rheumatology (Hoboken, N.J.)

Avec: Margo Tuerlings , Marcella van Hoolwerff , Evelyn Houtman , Eka H E D Suchiman , Nico Lakenberg , Hailiang Mei , Enrike H M J van der Linden , Rob R G H H Nelissen , Yolande Y F M Ramos , Rodrigo Coutinho de Almeida , Ingrid Meulenbelt

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.

Cell

Avec: Cindy G Boer , Konstantinos Hatzikotoulas , Lorraine Southam , Lilja Stefánsdóttir , Yanfei Zhang , Rodrigo Coutinho de Almeida , Tian T Wu , Jie Zheng , April Hartley , Maris Teder-Laving , Anne Heidi Skogholt , Chikashi Terao , Eleni Zengini , George Alexiadis , Andrei Barysenka , Gyda Bjornsdottir , Maiken E Gabrielsen , Arthur Gilly , Thorvaldur Ingvarsson , Marianne B Johnsen , Helgi Jonsson , Margreet Kloppenburg , Almut Luetge , Sigrun H Lund , Reedik Mägi , Massimo Mangino , Rob R G H H Nelissen , Manu Shivakumar , Julia Steinberg , Hiroshi Takuwa , Laurent F Thomas , Margo Tuerlings , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , George C Babis , Jason Pui Yin Cheung , Jae Hee Kang , Peter Kraft , Steven A Lietman , Dino Samartzis , P Eline Slagboom , Kari Stefansson , Unnur Thorsteinsdottir , Jonathan H Tobias , André G Uitterlinden , Bendik Winsvold , John-Anker Zwart , George Davey Smith , Pak Chung Sham , Gudmar Thorleifsson , Tom R Gaunt , Andrew P Morris , Ana M Valdes , Aspasia Tsezou , Kathryn S E Cheah , Shiro Ikegawa , Kristian Hveem , Tõnu Esko , J Mark Wilkinson , Ingrid Meulenbelt , Ming Ta Michael Lee , Joyce B J van Meurs , Unnur Styrkársdóttir , Eleftheria Zeggini

The role of TNFRSF11B in development of osteoarthritic cartilage.

Rheumatology (Oxford, England)

Avec: Alejandro Rodríguez Ruiz , Margo Tuerlings , Ankita Das , Rodrigo Coutinho de Almeida , H Eka D Suchiman , Rob G H H Nelissen , Yolande F M Ramos , Ingrid Meulenbelt

Characterizing the invasion of different breast cancer cell lines with distinct E-cadherin status in 3D using a microfluidic system.

Biomedical microdevices

Avec: H Eslami Amirabadi , M Tuerlings , A Hollestelle , S SahebAli , R Luttge , C C van Donkelaar , J W M Martens , J M J den Toonder

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants.

Arthritis research & therapy

Avec: Evelyn Houtman , Margo Tuerlings , Janne Riechelman , Eka H E D Suchiman , Robert J P van der Wal , Rob G H H Nelissen , Hailiang Mei , Yolande F M Ramos , Rodrigo Coutinho de Almeida , Ingrid Meulenbelt

A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis.

Human molecular genetics

Avec: Georgia Katsoula , Julia Steinberg , Margo Tuerlings , Rodrigo Coutinho de Almeida , Lorraine Southam , Diane Swift , Ingrid Meulenbelt , J Mark Wilkinson , Eleftheria Zeggini

Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants.

Rheumatology (Oxford, England)

Avec: Marcella van Hoolwerff , Margo Tuerlings , Imke J L Wijnen , H Eka D Suchiman , Davy Cats , Hailiang Mei , Rob G H H Nelissen , Henrike M J van der Linden-van der Zwaag , Yolande F M Ramos , Rodrigo Coutinho de Almeida , Ingrid Meulenbelt

Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis.

Rheumatology (Oxford, England)

Avec: Rodrigo Coutinho de Almeida , Margo Tuerlings , Yolande Ramos , Wouter Den Hollander , Eka Suchiman , Nico Lakenberg , Rob G H H Nelissen , Hailiang Mei , Ingrid Meulenbelt

Elucidating Epigenetic Regulation by Identifying Functional cis-Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage.

Arthritis & rheumatology (Hoboken, N.J.)

Avec: Marcella van Hoolwerff , Paula I Metselaar , Margo Tuerlings , H Eka D Suchiman , Nico Lakenberg , Yolande F M Ramos , Davy Cats , Rob G H H Nelissen , Demiën Broekhuis , Hailiang Mei , Rodrigo Coutinho de Almeida , Ingrid Meulenbelt

Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis.

Rheumatology (Oxford, England)

Avec: Margo Tuerlings , Marcella van Hoolwerff , Jessica M van Bokkum , H Eka D Suchiman , Nico Lakenberg , Demiën Broekhuis , Rob G H H Nelissen , Yolande F M Ramos , Hailiang Mei , Davy Cats , Rodrigo Coutinho de Almeida , Ingrid Meulenbelt

Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin.

Osteoarthritis and cartilage

Avec: E Houtman , R Coutinho de Almeida , M Tuerlings , H E D Suchiman , D Broekhuis , R G H H Nelissen , Y F M Ramos , J B J van Meurs , I Meulenbelt

Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes.

Rheumatology (Oxford, England)

Avec: Evelyn Houtman , Margo Tuerlings , H Eka D Suchiman , Nico Lakenberg , Frederique M F Cornelis , Hailiang Mei , Demiën Broekhuis , Rob G H H Nelissen , Rodrigo Coutinho de Almeida , Yolande F M Ramos , Rik J Lories , Luis J Cruz , Ingrid Meulenbelt

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells.

Cell and tissue research

Avec: Alejandro Rodríguez Ruiz , Amanda Dicks , Margo Tuerlings , Koen Schepers , Melissa van Pel , Rob G H H Nelissen , Christian Freund , Christine L Mummery , Valeria Orlova , Farshid Guilak , Ingrid Meulenbelt , Yolande F M Ramos

WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes.

Osteoarthritis and cartilage

Avec: M Tuerlings , G M C Janssen , I Boone , M van Hoolwerff , A Rodriguez Ruiz , E Houtman , H E D Suchiman , R J P van der Wal , R G H H Nelissen , R Coutinho de Almeida , P A van Veelen , Y F M Ramos , I Meulenbelt

Identified senescence endotypes in aged cartilage are reflected in the blood metabolome.

GeroScience

Avec: Ilja Boone , Margo Tuerlings , Rodrigo Coutinho de Almeida , Johannes Lehmann , Yolande Ramos , Rob Nelissen , Eline Slagboom , Peter de Keizer , Ingrid Meulenbelt

A human

Osteoarthritis and cartilage open

Avec: Ritchie G M Timmermans , Niek G C Bloks , Margo Tuerlings , Marcella van Hoolwerff , Rob G H H Nelissen , Robert J P van der Wal , Peter M van der Kraan , Arjen B Blom , Martijn H J van den Bosch , Yolande F M Ramos , Ingrid Meulenbelt

Réseau de co-auteurs

Ingrid Meulenbelt 13 collaborations

Rodrigo Coutinho de Almeida 11 collaborations

Rob G H H Nelissen 9 collaborations

Yolande F M Ramos 8 collaborations

Hailiang Mei 7 collaborations

Marcella van Hoolwerff 5 collaborations

Nico Lakenberg 5 collaborations

H Eka D Suchiman 5 collaborations

None None 4 collaborations

Evelyn Houtman 3 collaborations

M Tuerlings 3 collaborations

Davy Cats 3 collaborations

Demiën Broekhuis 3 collaborations

Eka H E D Suchiman 2 collaborations

Rob R G H H Nelissen 2 collaborations

Lorraine Southam 2 collaborations

Julia Steinberg 2 collaborations

J Mark Wilkinson 2 collaborations

Eleftheria Zeggini 2 collaborations

Alejandro Rodríguez Ruiz 2 collaborations

Robert J P van der Wal 2 collaborations

Yolande Ramos 2 collaborations

E Houtman 2 collaborations

R Coutinho de Almeida 2 collaborations

H E D Suchiman 2 collaborations

R G H H Nelissen 2 collaborations

Y F M Ramos 2 collaborations

I Meulenbelt 2 collaborations

Enrike H M J van der Linden 1 collaboration

Yolande Y F M Ramos 1 collaboration

Cindy G Boer 1 collaboration

Konstantinos Hatzikotoulas 1 collaboration

Lilja Stefánsdóttir 1 collaboration

Yanfei Zhang 1 collaboration

Tian T Wu 1 collaboration

Jie Zheng 1 collaboration

April Hartley 1 collaboration

Maris Teder-Laving 1 collaboration

Anne Heidi Skogholt 1 collaboration

Chikashi Terao 1 collaboration

Eleni Zengini 1 collaboration

George Alexiadis 1 collaboration

Andrei Barysenka 1 collaboration

Gyda Bjornsdottir 1 collaboration

Maiken E Gabrielsen 1 collaboration

Arthur Gilly 1 collaboration

Thorvaldur Ingvarsson 1 collaboration

Marianne B Johnsen 1 collaboration

Helgi Jonsson 1 collaboration

Margreet Kloppenburg 1 collaboration

Almut Luetge 1 collaboration

Sigrun H Lund 1 collaboration

Reedik Mägi 1 collaboration

Massimo Mangino 1 collaboration

Manu Shivakumar 1 collaboration

Hiroshi Takuwa 1 collaboration

Laurent F Thomas 1 collaboration

George C Babis 1 collaboration

Jason Pui Yin Cheung 1 collaboration

Jae Hee Kang 1 collaboration

Peter Kraft 1 collaboration

Steven A Lietman 1 collaboration

Dino Samartzis 1 collaboration

P Eline Slagboom 1 collaboration

Kari Stefansson 1 collaboration

Unnur Thorsteinsdottir 1 collaboration

Jonathan H Tobias 1 collaboration

André G Uitterlinden 1 collaboration

Bendik Winsvold 1 collaboration

John-Anker Zwart 1 collaboration

George Davey Smith 1 collaboration

Pak Chung Sham 1 collaboration

Gudmar Thorleifsson 1 collaboration

Tom R Gaunt 1 collaboration

Andrew P Morris 1 collaboration

Ana M Valdes 1 collaboration

Aspasia Tsezou 1 collaboration

Kathryn S E Cheah 1 collaboration

Shiro Ikegawa 1 collaboration

Kristian Hveem 1 collaboration

Tõnu Esko 1 collaboration

Ming Ta Michael Lee 1 collaboration

Joyce B J van Meurs 1 collaboration

Unnur Styrkársdóttir 1 collaboration

Ankita Das 1 collaboration

H Eslami Amirabadi 1 collaboration

A Hollestelle 1 collaboration

S SahebAli 1 collaboration

R Luttge 1 collaboration

C C van Donkelaar 1 collaboration

J W M Martens 1 collaboration

J M J den Toonder 1 collaboration

Janne Riechelman 1 collaboration

Georgia Katsoula 1 collaboration

Diane Swift 1 collaboration

Imke J L Wijnen 1 collaboration

Henrike M J van der Linden-van der Zwaag 1 collaboration

Wouter Den Hollander 1 collaboration

Eka Suchiman 1 collaboration

Paula I Metselaar 1 collaboration

Jessica M van Bokkum 1 collaboration

D Broekhuis 1 collaboration

J B J van Meurs 1 collaboration

Frederique M F Cornelis 1 collaboration

Rik J Lories 1 collaboration

Luis J Cruz 1 collaboration

Amanda Dicks 1 collaboration

Koen Schepers 1 collaboration

Melissa van Pel 1 collaboration

Christian Freund 1 collaboration

Christine L Mummery 1 collaboration

Valeria Orlova 1 collaboration

Farshid Guilak 1 collaboration

G M C Janssen 1 collaboration

I Boone 1 collaboration

M van Hoolwerff 1 collaboration

A Rodriguez Ruiz 1 collaboration

R J P van der Wal 1 collaboration

P A van Veelen 1 collaboration

Ilja Boone 1 collaboration

Johannes Lehmann 1 collaboration

Rob Nelissen 1 collaboration

Eline Slagboom 1 collaboration

Peter de Keizer 1 collaboration

Ritchie G M Timmermans 1 collaboration

Niek G C Bloks 1 collaboration

Peter M van der Kraan 1 collaboration

Arjen B Blom 1 collaboration

Martijn H J van den Bosch 1 collaboration