Maria Kleppe

Affiliations

Imago Biosciences Inc, San Francisco, CA.

Publications (12)

Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.

Blood

Avec: Qu Jiang , Johanna Stachelscheid , Johannes Bloehdorn , Alicja Pacholewska , Christoph Aszyk , Francien Grotenhuijs , Tony Müller , Ozlem Onder , Prerana Wagle , Carmen D Herling , Maria Kleppe , Zhefang Wang , Kevin R Coombes , Sandra Robrecht , Priya S Dalvi , Bianca Plosnita , Petra Mayer , Lynne V Abruzzo , Janine Altmüller , Birgit Gathof , Thorsten Persigehl , Kirsten Fischer , Billy Jebaraj , Hugh Y Rienhoff , Rupert Ecker , Yue Zhao , Christiane J Bruns , Stephan Stilgenbauer , Kojo Elenitoba-Johnson , Michael Hallek , Michal R Schweiger , Margarete Odenthal , Elena Vasyutina , Marco Herling

A dual-process view on medication adherence: The role of affect.

Journal of health psychology

Avec: Mieke Kleppe , Joyca Lacroix , Jaap Ham , Cees Midden

Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.

The Journal of clinical investigation

Avec: Simona Stivala , Tamara Codilupi , Sime Brkic , Anne Baerenwaldt , Nilabh Ghosh , Hui Hao-Shen , Stephan Dirnhofer , Matthias S Dettmer , Cedric Simillion , Beat A Kaufmann , Sophia Chiu , Matthew Keller , Maria Kleppe , Morgane Hilpert , Andreas S Buser , Jakob R Passweg , Thomas Radimerski , Radek C Skoda , Ross L Levine , Sara C Meyer

Objectively measured physical activity among treatment seeking children and adolescents with severe obesity and normal weight peers.

Obesity science & practice

Avec: Yngvild S Danielsen , Hanna F Skjåkødegård , Marit Mongstad , Sigurd W Hystad , Sven J G Olsson , Malin Kleppe , Petur B Juliusson , Bente Frisk

Characterization of Microbial Growth Potential in Antibody Drug IV Admixtures by Microbial Challenge.

Journal of pharmaceutical sciences

Avec: Qingyan Hu , James Wu , Ka Po Chu , Yuan Cao , Douglas Kamen , Mary Kleppe , Yuan Cheng , Dingjiang Liu , Mohammed Shameem

T cell-derived interferon-γ programs stem cell death in immune-mediated intestinal damage.

Science immunology

Avec: S Takashima , M L Martin , S A Jansen , Y Fu , J Bos , D Chandra , M H O'Connor , A M Mertelsmann , P Vinci , J Kuttiyara , S M Devlin , S Middendorp , M Calafiore , A Egorova , M Kleppe , Y Lo , N F Shroyer , E H Cheng , R L Levine , C Liu , R Kolesnick , C A Lindemans , A M Hanash

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML.

Blood

Avec: Bo-Rui Chen , Anagha Deshpande , Karina Barbosa , Maria Kleppe , Xue Lei , Narayana Yeddula , Pablo Sánchez Vela , Alexandre Rosa Campos , Robert J Wechsler-Reya , Anindya Bagchi , Soheil Meshinchi , Connie Eaves , Irmela Jeremias , Torsten Haferlach , David A Frank , Ze'ev Ronai , Sumit Chanda , Scott A Armstrong , Peter D Adams , Ross L Levine , Aniruddha J Deshpande

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis.

Blood

Avec: Andrew J Dunbar , Dongjoo Kim , Min Lu , Mirko Farina , Robert L Bowman , Julie L Yang , Young Park , Abdul Karzai , Wenbin Xiao , Zach Zaroogian , Kavi O'Connor , Shoron Mowla , Francesca Gobbo , Paola Verachi , Fabrizio Martelli , Giuseppe Sarli , Lijuan Xia , Nada Elmansy , Maria Kleppe , Zhuo Chen , Yang Xiao , Erin McGovern , Jenna Snyder , Aishwarya Krishnan , Corrine Hill , Keith Cordner , Anouar Zouak , Mohamed E Salama , Jayden Yohai , Eric Tucker , Jonathan Chen , Jing Zhou , Timothy McConnell , Anna R Migliaccio , Richard Koche , Raajit Rampal , Rong Fan , Ross L Levine , Ronald Hoffman

The clinical relevance of excisional margins after large loop excision of the transformation zone for the persistence of cervical dysplasia.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Avec: Bianca Reijntjes , Manon Eising , Marjolein Kleppe , Erwin Geuken , Jorien M Woolderink

LSD1 inhibition suppresses ASCL1 and de-represses YAP1 to drive potent activity against neuroendocrine prostate cancer.

bioRxiv : the preprint server for biology

Avec: A Mandl , S Jasmine , Teg Krueger , R Kumar , I M Coleman , S L Dalrymple , L Antony , D M Rosen , Y Jing , B Hanratty , R A Patel , L Jin-Yih , J Dias , C A Celatka , A E Tapper , M Kleppe , M Kanayama , V Speranzini , Y Z Wang , J Luo , E Corey , L A Sena , R A Casero , T Lotan , B J Trock , S K Kachhap , S R Denmeade , M A Carducci , A Mattevi , M C Haffner , P S Nelson , H Y Rienhoff , J T Isaacs , W N Brennen

Evaluating Clonal Hematopoiesis in Tumor-Infiltrating Leukocytes in Breast Cancer and Secondary Hematologic Malignancies.

Journal of the National Cancer Institute

Avec: Elizabeth A Comen , Robert L Bowman , Pier Selenica , Maria Kleppe , Noushin R Farnoud , Fresia Pareja , Britta Weigelt , Corinne E Hill , Abigail Alon , Felipe C Geyer , Guray Akturk , Jorge S Reis-Filho , Larry Norton , Ross L Levine

Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.

The Prostate

Avec: Sumer Jasmine , Adel Mandl , Timothy E G Krueger , Susan L Dalrymple , Lizamma Antony , Jennifer Dias , Cassandra A Celatka , Amy E Tapper , Maria Kleppe , Mayuko Kanayama , Yuezhou Jing , Valentina Speranzini , Yuzhuo Z Wang , Jun Luo , Bruce J Trock , Samuel R Denmeade , Michael A Carducci , Andrea Mattevi , Hugh Y Rienhoff , John T Isaacs , W Nathaniel Brennen

Réseau de co-auteurs

Ross L Levine 4 collaborations

Hugh Y Rienhoff 2 collaborations

M Kleppe 2 collaborations

Robert L Bowman 2 collaborations

Qu Jiang 1 collaboration

Johanna Stachelscheid 1 collaboration

Johannes Bloehdorn 1 collaboration

Alicja Pacholewska 1 collaboration

Christoph Aszyk 1 collaboration

Francien Grotenhuijs 1 collaboration

Tony Müller 1 collaboration

Ozlem Onder 1 collaboration

Prerana Wagle 1 collaboration

Carmen D Herling 1 collaboration

Zhefang Wang 1 collaboration

Kevin R Coombes 1 collaboration

Sandra Robrecht 1 collaboration

Priya S Dalvi 1 collaboration

Bianca Plosnita 1 collaboration

Petra Mayer 1 collaboration

Lynne V Abruzzo 1 collaboration

Janine Altmüller 1 collaboration

Birgit Gathof 1 collaboration

Thorsten Persigehl 1 collaboration

Kirsten Fischer 1 collaboration

Billy Jebaraj 1 collaboration

Rupert Ecker 1 collaboration

Yue Zhao 1 collaboration

Christiane J Bruns 1 collaboration

Stephan Stilgenbauer 1 collaboration

Kojo Elenitoba-Johnson 1 collaboration

Michael Hallek 1 collaboration

Michal R Schweiger 1 collaboration

Margarete Odenthal 1 collaboration

Elena Vasyutina 1 collaboration

Marco Herling 1 collaboration

Mieke Kleppe 1 collaboration

Joyca Lacroix 1 collaboration

Jaap Ham 1 collaboration

Cees Midden 1 collaboration

Simona Stivala 1 collaboration

Tamara Codilupi 1 collaboration

Sime Brkic 1 collaboration

Anne Baerenwaldt 1 collaboration

Nilabh Ghosh 1 collaboration

Hui Hao-Shen 1 collaboration

Stephan Dirnhofer 1 collaboration

Matthias S Dettmer 1 collaboration

Cedric Simillion 1 collaboration

Beat A Kaufmann 1 collaboration

Sophia Chiu 1 collaboration

Matthew Keller 1 collaboration

Morgane Hilpert 1 collaboration

Andreas S Buser 1 collaboration

Jakob R Passweg 1 collaboration

Thomas Radimerski 1 collaboration

Radek C Skoda 1 collaboration

Sara C Meyer 1 collaboration

Yngvild S Danielsen 1 collaboration

Hanna F Skjåkødegård 1 collaboration

Marit Mongstad 1 collaboration

Sigurd W Hystad 1 collaboration

Sven J G Olsson 1 collaboration

Malin Kleppe 1 collaboration

Petur B Juliusson 1 collaboration

Bente Frisk 1 collaboration

Qingyan Hu 1 collaboration

James Wu 1 collaboration

Ka Po Chu 1 collaboration

Yuan Cao 1 collaboration

Douglas Kamen 1 collaboration

Mary Kleppe 1 collaboration

Yuan Cheng 1 collaboration

Dingjiang Liu 1 collaboration

Mohammed Shameem 1 collaboration

S Takashima 1 collaboration

M L Martin 1 collaboration

S A Jansen 1 collaboration

Y Fu 1 collaboration

J Bos 1 collaboration

D Chandra 1 collaboration

M H O'Connor 1 collaboration

A M Mertelsmann 1 collaboration

P Vinci 1 collaboration

J Kuttiyara 1 collaboration

S M Devlin 1 collaboration

S Middendorp 1 collaboration

M Calafiore 1 collaboration

A Egorova 1 collaboration

Y Lo 1 collaboration

N F Shroyer 1 collaboration

E H Cheng 1 collaboration

R L Levine 1 collaboration

C Liu 1 collaboration

R Kolesnick 1 collaboration

C A Lindemans 1 collaboration

A M Hanash 1 collaboration

Bo-Rui Chen 1 collaboration

Anagha Deshpande 1 collaboration

Karina Barbosa 1 collaboration

Xue Lei 1 collaboration

Narayana Yeddula 1 collaboration

Pablo Sánchez Vela 1 collaboration

Alexandre Rosa Campos 1 collaboration

Robert J Wechsler-Reya 1 collaboration

Anindya Bagchi 1 collaboration

Soheil Meshinchi 1 collaboration

Connie Eaves 1 collaboration

Irmela Jeremias 1 collaboration

Torsten Haferlach 1 collaboration

David A Frank 1 collaboration

Ze'ev Ronai 1 collaboration

Sumit Chanda 1 collaboration

Scott A Armstrong 1 collaboration

Peter D Adams 1 collaboration

Aniruddha J Deshpande 1 collaboration

Andrew J Dunbar 1 collaboration

Dongjoo Kim 1 collaboration

Min Lu 1 collaboration

Mirko Farina 1 collaboration

Julie L Yang 1 collaboration

Young Park 1 collaboration

Abdul Karzai 1 collaboration

Wenbin Xiao 1 collaboration

Zach Zaroogian 1 collaboration

Kavi O'Connor 1 collaboration

Shoron Mowla 1 collaboration

Francesca Gobbo 1 collaboration

Paola Verachi 1 collaboration

Fabrizio Martelli 1 collaboration

Giuseppe Sarli 1 collaboration

Lijuan Xia 1 collaboration

Nada Elmansy 1 collaboration

Zhuo Chen 1 collaboration

Yang Xiao 1 collaboration

Erin McGovern 1 collaboration

Jenna Snyder 1 collaboration

Aishwarya Krishnan 1 collaboration

Corrine Hill 1 collaboration

Keith Cordner 1 collaboration

Anouar Zouak 1 collaboration

Mohamed E Salama 1 collaboration

Jayden Yohai 1 collaboration

Eric Tucker 1 collaboration

Jonathan Chen 1 collaboration

Jing Zhou 1 collaboration

Timothy McConnell 1 collaboration

Anna R Migliaccio 1 collaboration

Richard Koche 1 collaboration

Raajit Rampal 1 collaboration

Rong Fan 1 collaboration

Ronald Hoffman 1 collaboration

Bianca Reijntjes 1 collaboration

Manon Eising 1 collaboration

Marjolein Kleppe 1 collaboration

Erwin Geuken 1 collaboration

Jorien M Woolderink 1 collaboration

A Mandl 1 collaboration

S Jasmine 1 collaboration

Teg Krueger 1 collaboration

R Kumar 1 collaboration

I M Coleman 1 collaboration

S L Dalrymple 1 collaboration

L Antony 1 collaboration

D M Rosen 1 collaboration

Y Jing 1 collaboration

B Hanratty 1 collaboration

R A Patel 1 collaboration

L Jin-Yih 1 collaboration

J Dias 1 collaboration

C A Celatka 1 collaboration

A E Tapper 1 collaboration

M Kanayama 1 collaboration

V Speranzini 1 collaboration

Y Z Wang 1 collaboration

J Luo 1 collaboration

E Corey 1 collaboration

L A Sena 1 collaboration

R A Casero 1 collaboration

T Lotan 1 collaboration

B J Trock 1 collaboration

S K Kachhap 1 collaboration

S R Denmeade 1 collaboration

M A Carducci 1 collaboration

A Mattevi 1 collaboration

M C Haffner 1 collaboration

P S Nelson 1 collaboration

H Y Rienhoff 1 collaboration

J T Isaacs 1 collaboration

W N Brennen 1 collaboration

Elizabeth A Comen 1 collaboration

Pier Selenica 1 collaboration

Noushin R Farnoud 1 collaboration

Fresia Pareja 1 collaboration

Britta Weigelt 1 collaboration

Corinne E Hill 1 collaboration

Abigail Alon 1 collaboration

Felipe C Geyer 1 collaboration

Guray Akturk 1 collaboration

Jorge S Reis-Filho 1 collaboration

Larry Norton 1 collaboration

Sumer Jasmine 1 collaboration

Adel Mandl 1 collaboration

Timothy E G Krueger 1 collaboration

Susan L Dalrymple 1 collaboration

Lizamma Antony 1 collaboration

Jennifer Dias 1 collaboration

Cassandra A Celatka 1 collaboration

Amy E Tapper 1 collaboration

Mayuko Kanayama 1 collaboration

Yuezhou Jing 1 collaboration

Valentina Speranzini 1 collaboration

Yuzhuo Z Wang 1 collaboration

Jun Luo 1 collaboration

Bruce J Trock 1 collaboration

Samuel R Denmeade 1 collaboration

Michael A Carducci 1 collaboration

Andrea Mattevi 1 collaboration

John T Isaacs 1 collaboration

W Nathaniel Brennen 1 collaboration