Mark A Demitrack

Affiliations

Trevena Inc., Chesterbrook, PA, USA.

Publications (14)

Oliceridine Exhibits Improved Tolerability Compared to Morphine at Equianalgesic Conditions: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials.

Pain and therapy

Avec: Gregory B Hammer , Ashish K Khanna , Cathy Michalsky , Linda Wase , Mark A Demitrack , Roderick Little , Michael J Fossler , Sabry Ayad

Evaluating the Incidence of Opioid-Induced Respiratory Depression Associated with Oliceridine and Morphine as Measured by the Frequency and Average Cumulative Duration of Dosing Interruption in Patients Treated for Acute Postoperative Pain.

Clinical drug investigation

Avec: Sabry Ayad , Mark A Demitrack , David A Burt , Cathy Michalsky , Linda Wase , Michael J Fossler , Ashish K Khanna

Oliceridine is Associated with Reduced Risk of Vomiting and Need for Rescue Antiemetics Compared to Morphine: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials.

Pain and therapy

Avec: Timothy L Beard , Cathy Michalsky , Keith A Candiotti , Paul Rider , Linda Wase , Ashraf S Habib , Mark A Demitrack , Michael J Fossler , Eugene R Viscusi

The assessment of resistance to antidepressant treatment: Rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF).

Journal of psychiatric research

Avec: Harold A Sackeim , Scott T Aaronson , Mark T Bunker , Charles R Conway , Mark A Demitrack , Mark S George , Joan Prudic , Michael E Thase , A John Rush

APOLLO-2: A Randomized, Placebo and Active-Controlled Phase III Study Investigating Oliceridine (TRV130), a G Protein-Biased Ligand at the μ-Opioid Receptor, for Management of Moderate to Severe Acute Pain Following Abdominoplasty.

Pain practice : the official journal of World Institute of Pain

Avec: Neil K Singla , Franck Skobieranda , David G Soergel , Monica Salamea , David A Burt , Mark A Demitrack , Eugene R Viscusi

Benefit and Risk Evaluation of Biased μ-Receptor Agonist Oliceridine versus Morphine.

Anesthesiology

Avec: Albert Dahan , C Jan van Dam , Marieke Niesters , Monique van Velzen , Michael J Fossler , Mark A Demitrack , Erik Olofsen

Neurostructural Differences in Adolescents With Treatment-Resistant Depression and Treatment Effects of Transcranial Magnetic Stimulation.

The international journal of neuropsychopharmacology

Avec: Bhedita J Seewoo , Jennifer Rodger , Mark A Demitrack , Karen L Heart , John D Port , Jeffrey R Strawn , Paul E Croarkin

Left prefrontal transcranial magnetic stimulation for treatment-resistant depression in adolescents: a double-blind, randomized, sham-controlled trial.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Avec: Paul E Croarkin , Ahmed Z Elmaadawi , Scott T Aaronson , G Randolph Schrodt , Richard C Holbert , Sarah Verdoliva , Karen L Heart , Mark A Demitrack , Jeffrey R Strawn

Intracellular uptake of agents that block the hERG channel can confound the assessment of QT interval prolongation and arrhythmic risk.

Heart rhythm

Avec: Alexander Burashnikov , Hector Barajas-Martinez , Robert Cox , Mark A Demitrack , Michael J Fossler , Michael Kramer , Robert B Kleiman , Peter Kowey , Charles Antzelevitch

Budget impact and pharmacy costs with targeted use of oliceridine for postsurgical pain in patients at high risk of opioid-related adverse events.

Expert review of pharmacoeconomics & outcomes research

Avec: Kit N Simpson , Michael J Fossler , Linda Wase , Mark A Demitrack , Todd L Wandstrat

A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of Subcutaneous and Oral TRV250, a G Protein-Selective Delta Receptor Agonist, in Healthy Subjects.

CNS drugs

Avec: Michael J Fossler , Virginia Schmith , Stephen A Greene , Lauren Lohmer , Michael S Kramer , Kelly Arscott , Ian E James , Mark A Demitrack

Low Incidence of Postoperative Respiratory Depression with Oliceridine Compared to Morphine: A Retrospective Chart Analysis.

Pain research & management

Avec: Sergio Bergese , Richard Berkowitz , Paul Rider , Martin Ladouceur , Suzanne Griffith , Alvaro Segura Vasi , Kristina Cochrane , Linda Wase , Mark A Demitrack , Ashraf S Habib

Low Incidence of Opioid-Induced Respiratory Depression Observed with Oliceridine Regardless of Age or Body Mass Index: Exploratory Analysis from a Phase 3 Open-Label Trial in Postsurgical Pain.

Pain and therapy

Avec: Marek Brzezinski , Gregory B Hammer , Keith A Candiotti , Sergio D Bergese , Peter H Pan , Michael H Bourne , Cathy Michalsky , Linda Wase , Mark A Demitrack , Ashraf S Habib

Respiratory Effects of Biased Ligand Oliceridine in Older Volunteers: A Pharmacokinetic-Pharmacodynamic Comparison with Morphine.

Anesthesiology

Avec: Pieter Simons , Rutger van der Schrier , Maarten van Lemmen , Simone Jansen , Kiki W K Kuijpers , Monique van Velzen , Elise Sarton , Todd Nicklas , Cathy Michalsky , Mark A Demitrack , Michael Fossler , Erik Olofsen , Marieke Niesters , Albert Dahan

Réseau de co-auteurs

Michael J Fossler 7 collaborations

Linda Wase 6 collaborations

Cathy Michalsky 5 collaborations

Ashraf S Habib 3 collaborations

Gregory B Hammer 2 collaborations

Ashish K Khanna 2 collaborations

Sabry Ayad 2 collaborations

David A Burt 2 collaborations

Keith A Candiotti 2 collaborations

Paul Rider 2 collaborations

Eugene R Viscusi 2 collaborations

Scott T Aaronson 2 collaborations

Albert Dahan 2 collaborations

Marieke Niesters 2 collaborations

Monique van Velzen 2 collaborations

Erik Olofsen 2 collaborations

Karen L Heart 2 collaborations

Jeffrey R Strawn 2 collaborations

Paul E Croarkin 2 collaborations

Roderick Little 1 collaboration

Timothy L Beard 1 collaboration

Harold A Sackeim 1 collaboration

Mark T Bunker 1 collaboration

Charles R Conway 1 collaboration

Mark S George 1 collaboration

Joan Prudic 1 collaboration

Michael E Thase 1 collaboration

A John Rush 1 collaboration

Neil K Singla 1 collaboration

Franck Skobieranda 1 collaboration

David G Soergel 1 collaboration

Monica Salamea 1 collaboration

C Jan van Dam 1 collaboration

Bhedita J Seewoo 1 collaboration

Jennifer Rodger 1 collaboration

John D Port 1 collaboration

Ahmed Z Elmaadawi 1 collaboration

G Randolph Schrodt 1 collaboration

Richard C Holbert 1 collaboration

Sarah Verdoliva 1 collaboration

Alexander Burashnikov 1 collaboration

Hector Barajas-Martinez 1 collaboration

Robert Cox 1 collaboration

Michael Kramer 1 collaboration

Robert B Kleiman 1 collaboration

Peter Kowey 1 collaboration

Charles Antzelevitch 1 collaboration

Kit N Simpson 1 collaboration

Todd L Wandstrat 1 collaboration

Virginia Schmith 1 collaboration

Stephen A Greene 1 collaboration

Lauren Lohmer 1 collaboration

Michael S Kramer 1 collaboration

Kelly Arscott 1 collaboration

Ian E James 1 collaboration

Sergio Bergese 1 collaboration

Richard Berkowitz 1 collaboration

Martin Ladouceur 1 collaboration

Suzanne Griffith 1 collaboration

Alvaro Segura Vasi 1 collaboration

Kristina Cochrane 1 collaboration

Marek Brzezinski 1 collaboration

Sergio D Bergese 1 collaboration

Peter H Pan 1 collaboration

Michael H Bourne 1 collaboration

Pieter Simons 1 collaboration

Rutger van der Schrier 1 collaboration

Maarten van Lemmen 1 collaboration

Simone Jansen 1 collaboration

Kiki W K Kuijpers 1 collaboration

Elise Sarton 1 collaboration

Todd Nicklas 1 collaboration

Michael Fossler 1 collaboration