Matthias U Kassack

Affiliations

Institut für Pharmazeutische und Medizinische Chemie, Heinrich-Heine-Universität Düsseldorf , Universitätsstr. 1 , 40225 Düsseldorf , Germany.

Publications (31)

Synthesis of Peptoid-Based Class I-Selective Histone Deacetylase Inhibitors with Chemosensitizing Properties.

Journal of medicinal chemistry

Avec: Viktoria Krieger , Alexandra Hamacher , Fangyuan Cao , Katharina Stenzel , Christoph G W Gertzen , Linda Schäker-Hübner , Thomas Kurz , Holger Gohlke , Frank J Dekker , Matthias U Kassack , Finn K Hansen

Indole Diterpenoids from an Endophytic Penicillium sp.

Journal of natural products

Avec: Ni P Ariantari , Elena Ancheeva , Chenyin Wang , Attila Mándi , Tim-O Knedel , Tibor Kurtán , Chaidir Chaidir , Werner E G Müller , Matthias U Kassack , Christoph Janiak , Georgios Daletos , Peter Proksch

3-

Antimicrobial agents and chemotherapy

Avec: Nidja Rehberg , Edwin Omeje , Sherif S Ebada , Lasse van Geelen , Zhen Liu , Parichat Sureechatchayan , Matthias U Kassack , Thomas R Ioerger , Peter Proksch , Rainer Kalscheuer

Novel Histone Deacetylase (HDAC) Inhibitor Induces Apoptosis and Suppresses Invasion via E-Cadherin Upregulation in Pancreatic Ductal Adenocarcinoma (PDAC).

Pharmaceuticals (Basel, Switzerland)

Avec: Katja Schiedlauske , Alina Deipenbrock , Marc Pflieger , Alexandra Hamacher , Jan Hänsel , Matthias U Kassack , Thomas Kurz , Nicole E Teusch

The Antioxidant and HDAC-Inhibitor α-Lipoic Acid Is Synergistic with Exemestane in Estrogen Receptor-Positive Breast Cancer Cells.

International journal of molecular sciences

Avec: Laura S Pradel , Yu-Lin Ho , Holger Gohlke , Matthias U Kassack

Class I-Histone Deacetylase (HDAC) Inhibition is Superior to pan-HDAC Inhibition in Modulating Cisplatin Potency in High Grade Serous Ovarian Cancer Cell Lines.

International journal of molecular sciences

Avec: Jan J Bandolik , Alexandra Hamacher , Christian Schrenk , Robin Weishaupt , Matthias U Kassack

Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups.

Journal of medicinal chemistry

Avec: Nina Reßing , Melf Sönnichsen , Jeremy D Osko , Andrea Schöler , Julian Schliehe-Diecks , Alexander Skerhut , Arndt Borkhardt , Julia Hauer , Matthias U Kassack , David W Christianson , Sanil Bhatia , Finn K Hansen

Distinct influence of the anthracycline derivative doxorubicin on the differentiation efficacy of mESC-derived endothelial progenitor cells.

Biochimica et biophysica acta. Molecular cell research

Avec: Sarah K Jahn , Tatiana Hennicke , Matthias U Kassack , Leonie Drews , Andreas S Reichert , Gerhard Fritz

5-(Trifluoromethyl)-1,2,4-oxadiazole (TFMO)-based highly selective class IIa HDAC inhibitors exhibit synergistic anticancer activity in combination with bortezomib.

European journal of medicinal chemistry

Avec: Yodita Asfaha , Lukas M Bollmann , Alexander J Skerhut , Fabian Fischer , Nadine Horstick , Dennis Roth , Maria Wecker , Christian Mammen , Sander H J Smits , Georg Fluegen , Matthias U Kassack , Thomas Kurz

Hydrazide-Based Class I Selective HDAC Inhibitors Completely Reverse Chemoresistance Synergistically in Platinum-Resistant Solid Cancer Cells.

Journal of medicinal chemistry

Avec: Fabian B Kraft , Lukas Biermann , Linda Schäker-Hübner , Maria Hanl , Alexandra Hamacher , Matthias U Kassack , Finn K Hansen

Cyclic heptapeptides from the soil-derived fungus Clonostachys rosea.

Bioorganic & medicinal chemistry

Avec: Nada M Abdel-Wahab , Harwoko Harwoko , Werner E G Müller , Alexandra Hamacher , Matthias U Kassack , Mostafa A Fouad , Mohamed S Kamel , Wenhan Lin , Weaam Ebrahim , Zhen Liu , Peter Proksch

The tetrahydroxanthone-dimer phomoxanthone A is a strong inducer of apoptosis in cisplatin-resistant solid cancer cells.

Bioorganic & medicinal chemistry

Avec: Chenyin Wang , Laura Engelke , David Bickel , Alexandra Hamacher , Marian Frank , Peter Proksch , Holger Gohlke , Matthias U Kassack

Brominated Azaphilones from the Sponge-Associated Fungus

Journal of natural products

Avec: Marian Frank , Rudolf Hartmann , Malte Plenker , Attila Mándi , Tibor Kurtán , Ferhat Can Özkaya , Werner E G Müller , Matthias U Kassack , Alexandra Hamacher , Wenhan Lin , Zhen Liu , Peter Proksch

Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity.

ChemMedChem

Avec: Marc Pflieger , Melf Sönnichsen , Nadine Horstick-Muche , Jing Yang , Julian Schliehe-Diecks , Andrea Schöler , Arndt Borkhardt , Alexandra Hamacher , Matthias U Kassack , Finn K Hansen , Sanil Bhatia , Thomas Kurz

Triple Combination of Entinostat, a Bromodomain Inhibitor, and Cisplatin Is a Promising Treatment Option for Bladder Cancer.

Cancers

Avec: Lukas M Bollmann , Friedrich Lange , Alexandra Hamacher , Lukas Biermann , Linda Schäker-Hübner , Finn K Hansen , Matthias U Kassack

Hydroxamic Acids Immobilized on Resins (HAIRs): Synthesis of Dual-Targeting HDAC Inhibitors and HDAC Degraders (PROTACs).

Angewandte Chemie (International ed. in English)

Avec: Laura Sinatra , Jan J Bandolik , Martin Roatsch , Melf Sönnichsen , Clara T Schoeder , Alexandra Hamacher , Andrea Schöler , Arndt Borkhardt , Jens Meiler , Sanil Bhatia , Matthias U Kassack , Finn K Hansen

Novel α,β-unsaturated hydroxamic acid derivatives overcome cisplatin resistance.

Bioorganic & medicinal chemistry

Avec: Marc Pflieger , Alexandra Hamacher , Taner Öz , Nadine Horstick-Muche , Benedikt Boesen , Christian Schrenk , Matthias U Kassack , Thomas Kurz

Profiling of a suramin-derived compound library at recombinant human P2Y receptors identifies NF272 as a competitive but non-selective P2Y

Purinergic signalling

Avec: Nicole Brockmann , Parichat Sureechatchaiyan , David Müller , Tatiana Hennicke , Ralf Hausmann , Gerhard Fritz , Alexandra Hamacher , Matthias U Kassack

Cryptic Secondary Metabolites from the Sponge-Associated Fungus

Marine drugs

Avec: Marian Frank , Ferhat Can Özkaya , Werner E G Müller , Alexandra Hamacher , Matthias U Kassack , Wenhan Lin , Zhen Liu , Peter Proksch

Histone deacetylase inhibitor LMK235 attenuates vascular constriction and aortic remodelling in hypertension.

Journal of cellular and molecular medicine

Avec: Sin Young Choi , Hae Jin Kee , Simei Sun , Young Mi Seok , Yuhee Ryu , Gwi Ran Kim , Seung-Jung Kee , Marc Pflieger , Thomas Kurz , Matthias U Kassack , Myung Ho Jeong

New Acetophenones and Chromenes from the Leaves of

Molecules (Basel, Switzerland)

Avec: Kim-Thao Le , Jan J Bandolik , Matthias U Kassack , Kenneth R Wood , Claudia Paetzold , Marc S Appelhans , Claus M Passreiter

Synergistic induction of apoptosis in resistant head and neck carcinoma and leukemia by alkoxyamide-based histone deacetylase inhibitors.

European journal of medicinal chemistry

Avec: Leandro A Alves Avelar , Christian Schrenk , Melf Sönnichsen , Alexandra Hamacher , Finn K Hansen , Julian Schliehe-Diecks , Arndt Borkhardt , Sanil Bhatia , Matthias U Kassack , Thomas Kurz

Synergistic Interaction of the Class IIa HDAC Inhibitor CHDI0039 with Bortezomib in Head and Neck Cancer Cells.

International journal of molecular sciences

Avec: Christian Schrenk , Lukas M Bollmann , Corinna Haist , Arthur Bister , Constanze Wiek , Maria Wecker , Dennis Roth , Patrick Petzsch , Karl Köhrer , Alexandra Hamacher , Helmut Hanenberg , Georg Fluegen , Matthias U Kassack

Novel alkoxyamide-based histone deacetylase inhibitors reverse cisplatin resistance in chemoresistant cancer cells.

Bioorganic & medicinal chemistry

Avec: Yodita Asfaha , Christian Schrenk , Leandro A Alves Avelar , Friedrich Lange , Chenyin Wang , Jan J Bandolik , Alexandra Hamacher , Matthias U Kassack , Thomas Kurz

In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi).

International journal of molecular sciences

Avec: Annabelle Friedrich , Ann-Sophie Assmann , Lena Schumacher , Jana V Stuijvenberg , Matthias U Kassack , Wolfgang A Schulz , Wynand P Roos , Finn K Hansen , Marc Pflieger , Thomas Kurz , Gerhard Fritz

Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1.

Cancers

Avec: Chenyin Wang , Alexandra Hamacher , Patrick Petzsch , Karl Köhrer , Günter Niegisch , Michèle J Hoffmann , Wolfgang A Schulz , Matthias U Kassack

P2 Receptors Influence hMSCs Differentiation towards Endothelial Cell and Smooth Muscle Cell Lineages.

International journal of molecular sciences

Avec: Yu Zhang , Patrick Babczyk , Andreas Pansky , Matthias Ulrich Kassack , Edda Tobiasch

Recent advances in class IIa histone deacetylases research.

Bioorganic & medicinal chemistry

Avec: Yodita Asfaha , Christian Schrenk , Leandro A Alves Avelar , Alexandra Hamacher , Marc Pflieger , Matthias U Kassack , Thomas Kurz

Azaphilone pigments and macrodiolides from the coprophilous fungus Coniella fragariae.

Fitoterapia

Avec: Haiqian Yu , Julia Sperlich , Simon-Patrick Höfert , Christoph Janiak , Nicole Teusch , Fabian Stuhldreier , Sebastian Wesselborg , Chenyin Wang , Matthias U Kassack , Haofu Dai , Zhen Liu , Peter Proksch

Priming with HDAC Inhibitors Sensitizes Ovarian Cancer Cells to Treatment with Cisplatin and HSP90 Inhibitors.

International journal of molecular sciences

Avec: Ana J Rodrigues Moita , Jan J Bandolik , Finn K Hansen , Thomas Kurz , Alexandra Hamacher , Matthias U Kassack

The Novel Class IIa Selective Histone Deacetylase Inhibitor YAK540 Is Synergistic with Bortezomib in Leukemia Cell Lines.

International journal of molecular sciences

Avec: Lukas M Bollmann , Alexander J Skerhut , Yodita Asfaha , Nadine Horstick , Helmut Hanenberg , Alexandra Hamacher , Thomas Kurz , Matthias U Kassack

Réseau de co-auteurs

Alexandra Hamacher 20 collaborations

Thomas Kurz 12 collaborations

Finn K Hansen 9 collaborations

Peter Proksch 7 collaborations

Marc Pflieger 6 collaborations

Christian Schrenk 6 collaborations

Chenyin Wang 5 collaborations

Zhen Liu 5 collaborations

Jan J Bandolik 5 collaborations

Werner E G Müller 4 collaborations

Melf Sönnichsen 4 collaborations

Arndt Borkhardt 4 collaborations

Sanil Bhatia 4 collaborations

Yodita Asfaha 4 collaborations

Lukas M Bollmann 4 collaborations

Linda Schäker-Hübner 3 collaborations

Holger Gohlke 3 collaborations

Andrea Schöler 3 collaborations

Julian Schliehe-Diecks 3 collaborations

Gerhard Fritz 3 collaborations

Wenhan Lin 3 collaborations

Marian Frank 3 collaborations

Leandro A Alves Avelar 3 collaborations

Attila Mándi 2 collaborations

Tibor Kurtán 2 collaborations

Christoph Janiak 2 collaborations

Tatiana Hennicke 2 collaborations

Alexander J Skerhut 2 collaborations

Nadine Horstick 2 collaborations

Dennis Roth 2 collaborations

Maria Wecker 2 collaborations

Georg Fluegen 2 collaborations

Lukas Biermann 2 collaborations

Ferhat Can Özkaya 2 collaborations

Nadine Horstick-Muche 2 collaborations

Friedrich Lange 2 collaborations

Patrick Petzsch 2 collaborations

Karl Köhrer 2 collaborations

Helmut Hanenberg 2 collaborations

Wolfgang A Schulz 2 collaborations

Viktoria Krieger 1 collaboration

Fangyuan Cao 1 collaboration

Katharina Stenzel 1 collaboration

Christoph G W Gertzen 1 collaboration

Frank J Dekker 1 collaboration

Ni P Ariantari 1 collaboration

Elena Ancheeva 1 collaboration

Tim-O Knedel 1 collaboration

Chaidir Chaidir 1 collaboration

Georgios Daletos 1 collaboration

Nidja Rehberg 1 collaboration

Edwin Omeje 1 collaboration

Sherif S Ebada 1 collaboration

Lasse van Geelen 1 collaboration

Parichat Sureechatchayan 1 collaboration

Thomas R Ioerger 1 collaboration

Rainer Kalscheuer 1 collaboration

Katja Schiedlauske 1 collaboration

Alina Deipenbrock 1 collaboration

Jan Hänsel 1 collaboration

Nicole E Teusch 1 collaboration

Laura S Pradel 1 collaboration

Yu-Lin Ho 1 collaboration

Robin Weishaupt 1 collaboration

Nina Reßing 1 collaboration

Jeremy D Osko 1 collaboration

Alexander Skerhut 1 collaboration

Julia Hauer 1 collaboration

David W Christianson 1 collaboration

Sarah K Jahn 1 collaboration

Leonie Drews 1 collaboration

Andreas S Reichert 1 collaboration

Fabian Fischer 1 collaboration

Christian Mammen 1 collaboration

Sander H J Smits 1 collaboration

Fabian B Kraft 1 collaboration

Maria Hanl 1 collaboration

Nada M Abdel-Wahab 1 collaboration

Harwoko Harwoko 1 collaboration

Mostafa A Fouad 1 collaboration

Mohamed S Kamel 1 collaboration

Weaam Ebrahim 1 collaboration

Laura Engelke 1 collaboration

David Bickel 1 collaboration

Rudolf Hartmann 1 collaboration

Malte Plenker 1 collaboration

Jing Yang 1 collaboration

Laura Sinatra 1 collaboration

Martin Roatsch 1 collaboration

Clara T Schoeder 1 collaboration

Jens Meiler 1 collaboration

Taner Öz 1 collaboration

Benedikt Boesen 1 collaboration

Nicole Brockmann 1 collaboration

Parichat Sureechatchaiyan 1 collaboration

David Müller 1 collaboration

Ralf Hausmann 1 collaboration

Sin Young Choi 1 collaboration

Hae Jin Kee 1 collaboration

Simei Sun 1 collaboration

Young Mi Seok 1 collaboration

Yuhee Ryu 1 collaboration

Gwi Ran Kim 1 collaboration

Seung-Jung Kee 1 collaboration

Myung Ho Jeong 1 collaboration

Kim-Thao Le 1 collaboration

Kenneth R Wood 1 collaboration

Claudia Paetzold 1 collaboration

Marc S Appelhans 1 collaboration

Claus M Passreiter 1 collaboration

Corinna Haist 1 collaboration

Arthur Bister 1 collaboration

Constanze Wiek 1 collaboration

Annabelle Friedrich 1 collaboration

Ann-Sophie Assmann 1 collaboration

Lena Schumacher 1 collaboration

Jana V Stuijvenberg 1 collaboration

Wynand P Roos 1 collaboration

Günter Niegisch 1 collaboration

Michèle J Hoffmann 1 collaboration

Yu Zhang 1 collaboration

Patrick Babczyk 1 collaboration

Andreas Pansky 1 collaboration

Matthias Ulrich Kassack 1 collaboration

Edda Tobiasch 1 collaboration

Haiqian Yu 1 collaboration

Julia Sperlich 1 collaboration

Simon-Patrick Höfert 1 collaboration

Nicole Teusch 1 collaboration

Fabian Stuhldreier 1 collaboration

Sebastian Wesselborg 1 collaboration

Haofu Dai 1 collaboration

Ana J Rodrigues Moita 1 collaboration