Matthijs M Jore

Affiliations

Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.

Publications (23)

A Reproducible and Scalable Process for Manufacturing a Pfs48/45 Based

Frontiers in immunology

Avec: Susheel K Singh , Jordan Plieskatt , Bishwanath K Chourasia , Amanda Fabra-García , Asier Garcia-Senosiain , Vandana Singh , Karin Lövgren Bengtsson , Jenny M Reimer , Robert Sauerwein , Matthijs M Jore , Michael Theisen

Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose-escalation, phase 1 trial in healthy malaria-naive adults.

The Lancet. Infectious diseases

Avec: Saskia C van der Boor , Merel J Smit , Stijn W van Beek , Jordache Ramjith , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Peter Pickkers , Yimin Wu , Emily Locke , Shwu-Maan Lee , John Aponte , C Richter King , Ashley J Birkett , Kazutoyo Miura , Morolayo A Ayorinde , Robert W Sauerwein , Rob Ter Heine , Christian F Ockenhouse , Teun Bousema , Matthijs M Jore , Matthew B B McCall

Structure and function of a family of tick-derived complement inhibitors targeting properdin.

Nature communications

Avec: Katharina Braunger , Jiyoon Ahn , Matthijs M Jore , Steven Johnson , Terence T L Tang , Dennis V Pedersen , Gregers R Andersen , Susan M Lea

Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP.

Vaccine

Avec: Jordan Plieskatt , Peter Bang , Grith Krøyer Wood , Mohammad Naghizadeh , Susheel K Singh , Matthijs M Jore , Michael Theisen

Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.

Immunity

Avec: Brandon McLeod , Moustafa T Mabrouk , Kazutoyo Miura , Rashmi Ravichandran , Sally Kephart , Sophia Hailemariam , Thao P Pham , Anthony Semesi , Iga Kucharska , Prasun Kundu , Wei-Chiao Huang , Max Johnson , Alyssa Blackstone , Deleah Pettie , Michael Murphy , John C Kraft , Elizabeth M Leaf , Yang Jiao , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Jordache Ramjith , C Richter King , Randall S MacGill , Yimin Wu , Kelly K Lee , Matthijs M Jore , Neil P King , Jonathan F Lovell , Jean-Philippe Julien

Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.

Immunity

Avec: Amanda Fabra-García , Sophia Hailemariam , Roos M de Jong , Kirsten Janssen , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Danton Ivanochko , Anthony Semesi , Brandon McLeod , Martijn W Vos , Marloes H C de Bruijni , Judith M Bolscher , Marta Szabat , Stefanie Vogt , Lucas Kraft , Sherie Duncan , Moses R Kamya , Margaret E Feeney , Prasanna Jagannathan , Bryan Greenhouse , Koen J Dechering , Robert W Sauerwein , C Richter King , Randall S MacGill , Teun Bousema , Jean-Philippe Julien , Matthijs M Jore

An inhibitor of complement C5 provides structural insights into activation.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Martin P Reichhardt , Steven Johnson , Terence Tang , Thomas Morgan , Nchimunya Tebeka , Niko Popitsch , Justin C Deme , Matthijs M Jore , Susan M Lea

Frontiers in immunology

Avec: Susheel K Singh , Susan Thrane , Bishwanath K Chourasia , Karina Teelen , Wouter Graumans , Rianne Stoter , Geert-Jan van Gemert , Marga G van de Vegte-Bolmer , Morten A Nielsen , Ali Salanti , Adam F Sander , Robert W Sauerwein , Matthijs M Jore , Michael Theisen

A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial.

BMC medicine

Avec: M Alkema , M J Smit , C Marin-Mogollon , K Totté , K Teelen , G J van Gemert , M van de Vegte-Bolmer , B G Mordmüller , J M Reimer , K L Lövgren-Bengtsson , R W Sauerwein , T Bousema , J Plieskatt , M Theisen , M M Jore , M B B McCall

Antibody Therapy Goes to Insects: Monoclonal Antibodies Can Block Plasmodium Transmission to Mosquitoes.

Trends in parasitology

Avec: Camila H Coelho , Matthijs M Jore , Gaspar E Canepa , Carolina Barillas-Mury , Teun Bousema , Patrick E Duffy

Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoes.

NPJ vaccines

Avec: Roos M de Jong , Lisette Meerstein-Kessel , Dari F Da , Sandrine Nsango , Joseph D Challenger , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Elias Duarte , Noam Teyssier , Robert W Sauerwein , Thomas S Churcher , Roch K Dabire , Isabelle Morlais , Emily Locke , Martijn A Huynen , Teun Bousema , Matthijs M Jore

Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine.

NPJ vaccines

Avec: Susheel K Singh , Jordan Plieskatt , Bishwanath K Chourasia , Vandana Singh , Karin Lövgren Bengtsson , Jenny M Reimer , Renate C van Daalen , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Matthijs M Jore , Michael Theisen

Heterologous Expression and Evaluation of Novel

Frontiers in immunology

Avec: Roos M de Jong , Susheel K Singh , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Will J R Stone , Emily Locke , Jordan Plieskatt , Michael Theisen , Teun Bousema , Matthijs M Jore

Deceiving and escaping complement - the evasive journey of the malaria parasite.

Trends in parasitology

Avec: Maartje R Inklaar , Carolina Barillas-Mury , Matthijs M Jore

Pfs230 Domain 7 is targeted by a potent malaria transmission-blocking monoclonal antibody.

NPJ vaccines

Avec: Maartje R Inklaar , Roos M de Jong , Ezra T Bekkering , Hikaru Nagaoka , Felix L Fennemann , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Rianne Stoter , C Richter King , Nicholas I Proellochs , Teun Bousema , Eizo Takashima , Takafumi Tsuboi , Matthijs M Jore

Immunity against sexual stage Plasmodium falciparum and Plasmodium vivax parasites.

Immunological reviews

Avec: Roos M de Jong , Surafel K Tebeje , Lisette Meerstein-Kessel , Fitsum G Tadesse , Matthijs M Jore , Will Stone , Teun Bousema

Naturally acquired immunity against immature

Science translational medicine

Avec: Kathleen W Dantzler , Siyuan Ma , Priscilla Ngotho , Will J R Stone , Dingyin Tao , Sanna Rijpma , Mariana De Niz , Sandra K Nilsson Bark , Matthijs M Jore , Tonke K Raaijmakers , Angela M Early , Ceereena Ubaida-Mohien , Leandro Lemgruber , Joseph J Campo , Andy A Teng , Timothy Q Le , Cassidy L Walker , Patricia Hermand , Philippe Deterre , D Huw Davies , Phil Felgner , Isabelle Morlais , Dyann F Wirth , Daniel E Neafsey , Rhoel R Dinglasan , Miriam Laufer , Curtis Huttenhower , Karl Seydel , Terrie Taylor , Teun Bousema , Matthias Marti

Human antibodies against noncircumsporozoite proteins block Plasmodium falciparum parasite development in hepatocytes.

JCI insight

Avec: Amanda Fabra-García , Annie Sp Yang , Marije C Behet , Zen Yap , Youri van Waardenburg , Swarnendu Kaviraj , Kjerstin Lanke , Geert-Jan van Gemert , Matthijs M Jore , Teun Bousema , Robert W Sauerwein

Target-agnostic identification of human antibodies to

bioRxiv : the preprint server for biology

Avec: Axelle Amen , Randy Yoo , Amanda Fabra-García , Judith Bolscher , William J R Stone , Isabelle Bally , Sebastián Dergan-Dylon , Iga Kucharska , Roos M de Jong , Marloes de Bruijni , Teun Bousema , C Richter King , Randall S MacGill , Robert W Sauerwein , Jean-Philippe Julien , Pascal Poignard , Matthijs M Jore

Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.

Nature communications

Avec: Kuang-Ting Ko , Frank Lennartz , David Mekhaiel , Bora Guloglu , Arianna Marini , Danielle J Deuker , Carole A Long , Matthijs M Jore , Kazutoyo Miura , Sumi Biswas , Matthew K Higgins

Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230.

Immunity

Avec: Danton Ivanochko , Amanda Fabra-García , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Jocelyn Newton , Anthony Semesi , Marloes de Bruijni , Judith Bolscher , Jordache Ramjith , Marta Szabat , Stefanie Vogt , Lucas Kraft , Sherie Duncan , Shwu-Maan Lee , Moses R Kamya , Margaret E Feeney , Prasanna Jagannathan , Bryan Greenhouse , Robert W Sauerwein , C Richter King , Randall S MacGill , Teun Bousema , Matthijs M Jore , Jean-Philippe Julien

Modeling the Impact of a Highly Potent Plasmodium falciparum Transmission-Blocking Monoclonal Antibody in Areas of Seasonal Malaria Transmission.

The Journal of infectious diseases

Avec: Joseph D Challenger , Stijn W van Beek , Rob Ter Heine , Saskia C van der Boor , Giovanni D Charles , Merel J Smit , Chris Ockenhouse , John J Aponte , Matthew B B McCall , Matthijs M Jore , Thomas S Churcher , Teun Bousema

Naturally acquired antibodies to gametocyte antigens are associated with reduced transmission of

Frontiers in cellular and infection microbiology

Avec: Surafel K Tebeje , Wakweya Chali , Elifaged Hailemeskel , Jordache Ramjith , Abrham Gashaw , Temesgen Ashine , Desalegn Nebret , Endashaw Esayas , Tadele Emiru , Tizita Tsegaye , Karina Teelen , Kjerstin Lanke , Eizo Takashima , Takafumi Tsuboi , Nichole D Salinas , Niraj H Tolia , David Narum , Chris Drakeley , Benoit Witkowski , Amelie Vantaux , Matthijs M Jore , William J R Stone , Ivo S Hansen , Fitsum G Tadesse , Teun Bousema

Réseau de co-auteurs

Teun Bousema 13 collaborations

Geert-Jan van Gemert 10 collaborations

Karina Teelen 8 collaborations

Marga van de Vegte-Bolmer 8 collaborations

Robert W Sauerwein 7 collaborations

C Richter King 6 collaborations

Roos M de Jong 6 collaborations

Susheel K Singh 5 collaborations

Amanda Fabra-García 5 collaborations

Michael Theisen 5 collaborations

Jordan Plieskatt 4 collaborations

Jordache Ramjith 4 collaborations

Randall S MacGill 4 collaborations

Jean-Philippe Julien 4 collaborations

Bishwanath K Chourasia 3 collaborations

Emily Locke 3 collaborations

Kazutoyo Miura 3 collaborations

Anthony Semesi 3 collaborations

Vandana Singh 2 collaborations

Karin Lövgren Bengtsson 2 collaborations

Jenny M Reimer 2 collaborations

Saskia C van der Boor 2 collaborations

Merel J Smit 2 collaborations

Stijn W van Beek 2 collaborations

Yimin Wu 2 collaborations

Shwu-Maan Lee 2 collaborations

Rob Ter Heine 2 collaborations

Matthew B B McCall 2 collaborations

Steven Johnson 2 collaborations

Susan M Lea 2 collaborations

Brandon McLeod 2 collaborations

Sophia Hailemariam 2 collaborations

Iga Kucharska 2 collaborations

Danton Ivanochko 2 collaborations

Marta Szabat 2 collaborations

Stefanie Vogt 2 collaborations

Lucas Kraft 2 collaborations

Sherie Duncan 2 collaborations

Moses R Kamya 2 collaborations

Margaret E Feeney 2 collaborations

Prasanna Jagannathan 2 collaborations

Bryan Greenhouse 2 collaborations

Rianne Stoter 2 collaborations

Carolina Barillas-Mury 2 collaborations

Lisette Meerstein-Kessel 2 collaborations

Joseph D Challenger 2 collaborations

Thomas S Churcher 2 collaborations

Isabelle Morlais 2 collaborations

Will J R Stone 2 collaborations

Maartje R Inklaar 2 collaborations

Eizo Takashima 2 collaborations

Takafumi Tsuboi 2 collaborations

Surafel K Tebeje 2 collaborations

Fitsum G Tadesse 2 collaborations

Kjerstin Lanke 2 collaborations

Judith Bolscher 2 collaborations

William J R Stone 2 collaborations

Marloes de Bruijni 2 collaborations

Asier Garcia-Senosiain 1 collaboration

Robert Sauerwein 1 collaboration

Peter Pickkers 1 collaboration

John Aponte 1 collaboration

Ashley J Birkett 1 collaboration

Morolayo A Ayorinde 1 collaboration

Christian F Ockenhouse 1 collaboration

Katharina Braunger 1 collaboration

Jiyoon Ahn 1 collaboration

Terence T L Tang 1 collaboration

Dennis V Pedersen 1 collaboration

Gregers R Andersen 1 collaboration

Peter Bang 1 collaboration

Grith Krøyer Wood 1 collaboration

Mohammad Naghizadeh 1 collaboration

Moustafa T Mabrouk 1 collaboration

Rashmi Ravichandran 1 collaboration

Sally Kephart 1 collaboration

Thao P Pham 1 collaboration

Prasun Kundu 1 collaboration

Wei-Chiao Huang 1 collaboration

Max Johnson 1 collaboration

Alyssa Blackstone 1 collaboration

Deleah Pettie 1 collaboration

Michael Murphy 1 collaboration

John C Kraft 1 collaboration

Elizabeth M Leaf 1 collaboration

Yang Jiao 1 collaboration

Kelly K Lee 1 collaboration

Neil P King 1 collaboration

Jonathan F Lovell 1 collaboration

Kirsten Janssen 1 collaboration

Martijn W Vos 1 collaboration

Marloes H C de Bruijni 1 collaboration

Judith M Bolscher 1 collaboration

Koen J Dechering 1 collaboration

Martin P Reichhardt 1 collaboration

Terence Tang 1 collaboration

Thomas Morgan 1 collaboration

Nchimunya Tebeka 1 collaboration

Niko Popitsch 1 collaboration

Justin C Deme 1 collaboration

Susan Thrane 1 collaboration

Wouter Graumans 1 collaboration

Marga G van de Vegte-Bolmer 1 collaboration

Morten A Nielsen 1 collaboration

Ali Salanti 1 collaboration

Adam F Sander 1 collaboration

M Alkema 1 collaboration

M J Smit 1 collaboration

C Marin-Mogollon 1 collaboration

K Totté 1 collaboration

K Teelen 1 collaboration

G J van Gemert 1 collaboration

M van de Vegte-Bolmer 1 collaboration

B G Mordmüller 1 collaboration

J M Reimer 1 collaboration

K L Lövgren-Bengtsson 1 collaboration

R W Sauerwein 1 collaboration

T Bousema 1 collaboration

J Plieskatt 1 collaboration

M Theisen 1 collaboration

M M Jore 1 collaboration

M B B McCall 1 collaboration

Camila H Coelho 1 collaboration

Gaspar E Canepa 1 collaboration

Patrick E Duffy 1 collaboration

Dari F Da 1 collaboration

Sandrine Nsango 1 collaboration

Elias Duarte 1 collaboration

Noam Teyssier 1 collaboration

Roch K Dabire 1 collaboration

Martijn A Huynen 1 collaboration

Renate C van Daalen 1 collaboration

Ezra T Bekkering 1 collaboration

Hikaru Nagaoka 1 collaboration

Felix L Fennemann 1 collaboration

Nicholas I Proellochs 1 collaboration

Will Stone 1 collaboration

Kathleen W Dantzler 1 collaboration

Siyuan Ma 1 collaboration

Priscilla Ngotho 1 collaboration

Dingyin Tao 1 collaboration

Sanna Rijpma 1 collaboration

Mariana De Niz 1 collaboration

Sandra K Nilsson Bark 1 collaboration

Tonke K Raaijmakers 1 collaboration

Angela M Early 1 collaboration

Ceereena Ubaida-Mohien 1 collaboration

Leandro Lemgruber 1 collaboration

Joseph J Campo 1 collaboration

Andy A Teng 1 collaboration

Timothy Q Le 1 collaboration

Cassidy L Walker 1 collaboration

Patricia Hermand 1 collaboration

Philippe Deterre 1 collaboration

D Huw Davies 1 collaboration

Phil Felgner 1 collaboration

Dyann F Wirth 1 collaboration

Daniel E Neafsey 1 collaboration

Rhoel R Dinglasan 1 collaboration

Miriam Laufer 1 collaboration

Curtis Huttenhower 1 collaboration

Karl Seydel 1 collaboration

Terrie Taylor 1 collaboration

Matthias Marti 1 collaboration

Annie Sp Yang 1 collaboration

Marije C Behet 1 collaboration

Zen Yap 1 collaboration

Youri van Waardenburg 1 collaboration

Swarnendu Kaviraj 1 collaboration

Axelle Amen 1 collaboration

Randy Yoo 1 collaboration

Isabelle Bally 1 collaboration

Sebastián Dergan-Dylon 1 collaboration

Pascal Poignard 1 collaboration

Kuang-Ting Ko 1 collaboration

Frank Lennartz 1 collaboration

David Mekhaiel 1 collaboration

Bora Guloglu 1 collaboration

Arianna Marini 1 collaboration

Danielle J Deuker 1 collaboration

Carole A Long 1 collaboration

Sumi Biswas 1 collaboration

Matthew K Higgins 1 collaboration

Jocelyn Newton 1 collaboration

Giovanni D Charles 1 collaboration

Chris Ockenhouse 1 collaboration

John J Aponte 1 collaboration

Wakweya Chali 1 collaboration

Elifaged Hailemeskel 1 collaboration

Abrham Gashaw 1 collaboration

Temesgen Ashine 1 collaboration

Desalegn Nebret 1 collaboration

Endashaw Esayas 1 collaboration

Tadele Emiru 1 collaboration

Tizita Tsegaye 1 collaboration

Nichole D Salinas 1 collaboration

Niraj H Tolia 1 collaboration

David Narum 1 collaboration

Chris Drakeley 1 collaboration

Benoit Witkowski 1 collaboration

Amelie Vantaux 1 collaboration

Ivo S Hansen 1 collaboration