Michael J Thorpy

Affiliations

Montefiore Medical Center, 111 East 210th Street, Bronx, NY, 10467-2509, USA.

Publications (37)

Solriamfetol for the Treatment of Excessive Daytime Sleepiness in Participants with Narcolepsy with and without Cataplexy: Subgroup Analysis of Efficacy and Safety Data by Cataplexy Status in a Randomized Controlled Trial.

CNS drugs

Avec: Yves Dauvilliers , Colin Shapiro , Geert Mayer , Gert Jan Lammers , Helene Emsellem , Giuseppe Plazzi , Dan Chen , Lawrence P Carter , Lawrence Lee , Jed Black , Michael J Thorpy

Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate [LXB]; JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy.

Sleep

Avec: Richard K Bogan , Michael J Thorpy , Yves Dauvilliers , Markku Partinen , Rafael Del Rio Villegas , Nancy Foldvary-Schaefer , Roman Skowronski , Lihua Tang , Franck Skobieranda , Karel Šonka

Clinical considerations for the diagnosis of idiopathic hypersomnia.

Sleep medicine reviews

Avec: Yves Dauvilliers , Richard K Bogan , Isabelle Arnulf , Thomas E Scammell , Erik K St Louis , Michael J Thorpy

Dosing Optimization of Low-Sodium Oxybate in Narcolepsy and Idiopathic Hypersomnia in Adults: Consensus Recommendations.

Neurology and therapy

Avec: Anne Marie Morse , Richard K Bogan , Asim Roy , Michael J Thorpy

Measures of functional outcomes, work productivity, and quality of life from a randomized, phase 3 study of solriamfetol in participants with narcolepsy.

Sleep medicine

Avec: Helene A Emsellem , Michael J Thorpy , Gert Jan Lammers , Colin M Shapiro , Geert Mayer , Giuseppe Plazzi , Dan Chen , Lawrence P Carter , Kathleen F Villa , Lawrence Lee , Diane Menno , Jed Black , Yves Dauvilliers

The Nexus Narcolepsy Registry: methodology, study population characteristics, and patterns and predictors of narcolepsy diagnosis.

Sleep medicine

Avec: Maurice M Ohayon , Michael J Thorpy , Ginger Carls , Jed Black , Miriam Cisternas , David J Pasta , Shay Bujanover , Danielle Hyman , Kathleen F Villa

Changes in Cataplexy Frequency in a Clinical Trial of Lower-Sodium Oxybate with Taper and Discontinuation of Other Anticataplectic Medications.

CNS drugs

Avec: Yves Dauvilliers , Karel Šonka , Richard K Bogan , Markku Partinen , Rafael Del Rio Villegas , Nancy Foldvary-Schaefer , Roman Skowronski , Abby Chen , Jed Black , Franck Skobieranda , Michael J Thorpy

Solriamfetol Titration & AdministRaTion (START) in Patients With Narcolepsy.

Clinical therapeutics

Avec: Michael J Thorpy , Danielle Hyman , Gregory S Parks , Abby Chen , Catherine Foley , Beth Baldys , Diane Ito , Haramandeep Singh

Once-nightly sodium oxybate (FT218) improved symptoms of disrupted nighttime sleep in people with narcolepsy: a plain language summary.

Journal of comparative effectiveness research

Avec: Thomas Roth , Michael J Thorpy , Clete A Kushida , Matthew Horsnell , Jennifer Gudeman

Improvement in sleep latency with extended-release once-nightly sodium oxybate for the treatment of adults with narcolepsy: Analysis from the phase 3 REST-ON clinical trial.

Sleep medicine: X

Avec: Michael J Thorpy , Clete A Kushida , Richard Bogan , John Winkelman , Maurice M Ohayon , Colin M Shapiro , Jennifer Gudeman

A randomized study of solriamfetol for excessive sleepiness in narcolepsy.

Annals of neurology

Avec: Michael J Thorpy , Colin Shapiro , Geert Mayer , Bruce C Corser , Helene Emsellem , Giuseppe Plazzi , Dan Chen , Lawrence P Carter , Hao Wang , Yuan Lu , Jed Black , Yves Dauvilliers

Recently Approved and Upcoming Treatments for Narcolepsy.

CNS drugs

Avec: Michael J Thorpy

The Xyrem

Drugs - real world outcomes

Avec: Michael J Strunc , Jed Black , Prasheel Lillaney , Judi Profant , Sherice Mills , Shay Bujanover , Michael J Thorpy

Calcium, Magnesium, Potassium, and Sodium Oxybates Oral Solution: A Lower-Sodium Alternative for Cataplexy or Excessive Daytime Sleepiness Associated with Narcolepsy.

Nature and science of sleep

Avec: Yves Dauvilliers , Richard K Bogan , Karel Šonka , Markku Partinen , Nancy Foldvary-Schaefer , Michael J Thorpy

Brain fog in central disorders of hypersomnolence: a review.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Avec: Russell Rosenberg , Michael J Thorpy , Karl Doghramji , Anne Marie Morse

Randomized, crossover, open-label study of the relative bioavailability and safety of FT218, a once-nightly sodium oxybate formulation: Phase 1 study in healthy volunteers.

Sleep medicine

Avec: Richard Bogan , Michael J Thorpy , John W Winkelman , Jordan Dubow , Jennifer Gudeman , David Seiden

Efficacy and Safety of Lower-Sodium Oxybate in an Open-Label Titration Period of a Phase 3 Clinical Study in Adults with Idiopathic Hypersomnia.

Nature and science of sleep

Avec: Michael J Thorpy , Isabelle Arnulf , Nancy Foldvary-Schaefer , Anne Marie Morse , Karel Šonka , Patricia Chandler , Luke Hickey , Abby Chen , Jed Black , Amanda Sterkel , Dan Chen , Richard K Bogan , Yves Dauvilliers

REM sleep in narcolepsy.

Sleep medicine reviews

Avec: Michael J Thorpy , Jerome M Siegel , Yves Dauvilliers

Improvements in daytime sleepiness and disrupted nighttime sleep with once-nightly sodium oxybate in people with narcolepsy type 1 and type 2: a plain language summary.

Journal of comparative effectiveness research

Avec: Yves Dauvilliers , Thomas Roth , Richard Bogan , Michael J Thorpy , Anne Marie Morse , Fèri Ascencion , Jennifer Gudeman

Update on the pharmacologic management of narcolepsy: mechanisms of action and clinical implications.

Sleep medicine

Avec: Michael J Thorpy , Richard K Bogan

2018 worldwide survey of health-care providers caring for patients with narcolepsy: WSS narcolepsy task force.

Sleep medicine

Avec: Leon Rosenthal , Michael J Thorpy , Sona Nevsimalova , Geert Mayer , Fang Han , Yves Dauvilliers

Once-nightly sodium oxybate (FT218) demonstrated improvement of symptoms in a phase 3 randomized clinical trial in patients with narcolepsy.

Sleep

Avec: Clete A Kushida , Colin M Shapiro , Thomas Roth , Michael J Thorpy , Bruce C Corser , Akinyemi O Ajayi , Russell Rosenberg , Asim Roy , David Seiden , Jordan Dubow , Yves Dauvilliers

Current Understanding of Narcolepsy 1 and its Comorbidities: What Clinicians Need to Know.

Advances in therapy

Avec: Lois E Krahn , Phyllis C Zee , Michael J Thorpy

Effect of FT218, a Once-Nightly Sodium Oxybate Formulation, on Disrupted Nighttime Sleep in Patients with Narcolepsy: Results from the Randomized Phase III REST-ON Trial.

CNS drugs

Avec: Thomas Roth , Yves Dauvilliers , Michael J Thorpy , Clete Kushida , Bruce C Corser , Richard Bogan , Russell Rosenberg , Jordan Dubow , David Seiden

Long-Term Safety and Tolerability During a Clinical Trial and Open-Label Extension of Low-Sodium Oxybate in Participants with Narcolepsy with Cataplexy.

CNS drugs

Avec: Richard K Bogan , Nancy Foldvary-Schaefer , Roman Skowronski , Abby Chen , Michael J Thorpy

Long-term efficacy and safety of low-sodium oxybate in an open-label extension period of a placebo-controlled, double-blind, randomized withdrawal study in adults with idiopathic hypersomnia.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Avec: Anne Marie Morse , Yves Dauvilliers , Isabelle Arnulf , Michael J Thorpy , Nancy Foldvary-Schaefer , Patricia Chandler , Abby Chen , Luke Hickey , Jed Black , Richard K Bogan

Efficacy of once-nightly sodium oxybate (FT218) on daytime symptoms in individuals with narcolepsy with or without concomitant alerting agent use: A post hoc analysis from the phase 3 REST-ON trial.

Sleep medicine

Avec: Yves Dauvilliers , Thomas Roth , Richard Bogan , Michael J Thorpy , Anne Marie Morse , Asim Roy , Jennifer Gudeman

Efficacy of pitolisant in patients with high burden of narcolepsy symptoms: pooled analysis of short-term, placebo-controlled studies.

Sleep medicine

Avec: Craig W Davis , Ulf Kallweit , Jean-Charles Schwartz , Lois E Krahn , Ben Vaughn , Michael J Thorpy

Neurobiological and immunogenetic aspects of narcolepsy: Implications for pharmacotherapy.

Sleep medicine reviews

Avec: Steven T Szabo , Michael J Thorpy , Geert Mayer , John H Peever , Thomas S Kilduff

Assessing the impact of sodium oxybate treatment on functioning, productivity, and health-related quality of life in patients with narcolepsy: findings from the Nexus Narcolepsy Registry (waves 1-4).

Sleep medicine

Avec: Michael J Thorpy , Maurice M Ohayon , Ginger Carls , Jed Black , David J Pasta , Danielle L Hyman , Kathleen F Villa

Incidence and duration of common early-onset adverse events in randomized controlled trials of solriamfetol for treatment of excessive daytime sleepiness in obstructive sleep apnea and narcolepsy.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Avec: Russell Rosenberg , Michael J Thorpy , Yves Dauvilliers , Paula K Schweitzer , Gary Zammit , Mark Gotfried , Shay Bujanover , Brian Scheckner , Atul Malhotra

Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomised withdrawal study.

The Lancet. Neurology

Avec: Yves Dauvilliers , Isabelle Arnulf , Nancy Foldvary-Schaefer , Anne Marie Morse , Karel Šonka , Michael J Thorpy , Emmanuel Mignot , Patricia Chandler , Rupa Parvataneni , Jed Black , Amanda Sterkel , Dan Chen , Franck Skobieranda , Richard K Bogan

Clinical considerations in the treatment of idiopathic hypersomnia.

Sleep medicine

Avec: Michael J Thorpy , Lois Krahn , Chad Ruoff , Nancy Foldvary-Schaefer

Solriamfetol Titration and AdministRaTion (START) in Patients with Obstructive Sleep Apnea: A Retrospective Chart Review and Hypothetical Patient Scenario.

Advances in therapy

Avec: Haramandeep Singh , Danielle Hyman , Gregory S Parks , Abby Chen , Catherine Foley , Beth Baldys , Diane Ito , Michael J Thorpy

Clinician Preferences for Oxybate Treatment for Narcolepsy: Survey and Discrete Choice Experiment.

Advances in therapy

Avec: Anne Marie Morse , Lois Krahn , Julie Flygare , Clete Kushida , Michael J Thorpy , Amod Athavale , Jennifer Gudeman

Efficacy of once-nightly sodium oxybate (FT218) in narcolepsy type 1 and type 2: post hoc analysis from the Phase 3 REST-ON Trial.

Sleep

Avec: Yves Dauvilliers , Thomas Roth , Richard Bogan , Michael J Thorpy , Anne Marie Morse , Asim Roy , Jordan Dubow , Jennifer Gudeman

Cataplexy response with extended-release once-nightly sodium oxybate: Post hoc responder analyses from the phase 3 REST-ON clinical trial.

Sleep medicine: X

Avec: Michael J Thorpy , Clete A Kushida , Richard Bogan , Akinyemi O Ajayi , Bruce C Corser , Jennifer Gudeman

Réseau de co-auteurs

Yves Dauvilliers 18 collaborations

Jed Black 10 collaborations

Richard K Bogan 10 collaborations

Anne Marie Morse 9 collaborations

Nancy Foldvary-Schaefer 8 collaborations

Jennifer Gudeman 8 collaborations

Richard Bogan 7 collaborations

Abby Chen 6 collaborations

Thomas Roth 6 collaborations

Geert Mayer 5 collaborations

Dan Chen 5 collaborations

Karel Šonka 5 collaborations

Isabelle Arnulf 4 collaborations

Asim Roy 4 collaborations

Clete A Kushida 4 collaborations

Bruce C Corser 4 collaborations

Russell Rosenberg 4 collaborations

Jordan Dubow 4 collaborations

Giuseppe Plazzi 3 collaborations

Lawrence P Carter 3 collaborations

Markku Partinen 3 collaborations

Roman Skowronski 3 collaborations

Franck Skobieranda 3 collaborations

Colin M Shapiro 3 collaborations

Kathleen F Villa 3 collaborations

Maurice M Ohayon 3 collaborations

Shay Bujanover 3 collaborations

Danielle Hyman 3 collaborations

David Seiden 3 collaborations

Patricia Chandler 3 collaborations

Colin Shapiro 2 collaborations

Gert Jan Lammers 2 collaborations

Helene Emsellem 2 collaborations

Lawrence Lee 2 collaborations

Rafael Del Rio Villegas 2 collaborations

Ginger Carls 2 collaborations

David J Pasta 2 collaborations

Gregory S Parks 2 collaborations

Catherine Foley 2 collaborations

Beth Baldys 2 collaborations

Diane Ito 2 collaborations

Haramandeep Singh 2 collaborations

Luke Hickey 2 collaborations

Amanda Sterkel 2 collaborations

Akinyemi O Ajayi 2 collaborations

Lois E Krahn 2 collaborations

Clete Kushida 2 collaborations

Lois Krahn 2 collaborations

Lihua Tang 1 collaboration

Thomas E Scammell 1 collaboration

Erik K St Louis 1 collaboration

Helene A Emsellem 1 collaboration

Diane Menno 1 collaboration

Miriam Cisternas 1 collaboration

Matthew Horsnell 1 collaboration

John Winkelman 1 collaboration

Hao Wang 1 collaboration

Yuan Lu 1 collaboration

Michael J Strunc 1 collaboration

Prasheel Lillaney 1 collaboration

Judi Profant 1 collaboration

Sherice Mills 1 collaboration

Karl Doghramji 1 collaboration

John W Winkelman 1 collaboration

Jerome M Siegel 1 collaboration

Fèri Ascencion 1 collaboration

Leon Rosenthal 1 collaboration

Sona Nevsimalova 1 collaboration

Fang Han 1 collaboration

Phyllis C Zee 1 collaboration

Craig W Davis 1 collaboration

Ulf Kallweit 1 collaboration

Jean-Charles Schwartz 1 collaboration

Ben Vaughn 1 collaboration

Steven T Szabo 1 collaboration

John H Peever 1 collaboration

Thomas S Kilduff 1 collaboration

Danielle L Hyman 1 collaboration

Paula K Schweitzer 1 collaboration

Gary Zammit 1 collaboration

Mark Gotfried 1 collaboration

Brian Scheckner 1 collaboration

Atul Malhotra 1 collaboration

Emmanuel Mignot 1 collaboration

Rupa Parvataneni 1 collaboration

Chad Ruoff 1 collaboration

Julie Flygare 1 collaboration

Amod Athavale 1 collaboration