Monique M A Verstegen

Affiliations

Department of Surgery, Erasmus MC-University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands.

Publications (22)

Characterization of gut-homing molecules in non-endstage livers of patients with primary sclerosing cholangitis and inflammatory bowel disease.

Journal of translational autoimmunity

Avec: Manon de Krijger , Thijmen Visseren , Manon E Wildenberg , Gerrit K J Hooijer , Monique M A Verstegen , Luc J W van der Laan , Wouter J de Jonge , Joanne Verheij , Cyriel Y Ponsioen

Rotavirus Infection and Cytopathogenesis in Human Biliary Organoids Potentially Recapitulate Biliary Atresia Development.

mBio

Avec: Sunrui Chen , Pengfei Li , Yining Wang , Yuebang Yin , Petra E de Ruiter , Monique M A Verstegen , Maikel P Peppelenbosch , Luc J W van der Laan , Qiuwei Pan

Experimental models to unravel the molecular pathogenesis, cell of origin and stem cell properties of cholangiocarcinoma.

Liver international : official journal of the International Association for the Study of the Liver

Avec: Silvestre Vicent , Ruby Lieshout , Anna Saborowski , Monique M A Verstegen , Chiara Raggi , Stefania Recalcati , Pietro Invernizzi , Luc J W van der Laan , Domenico Alvaro , Diego F Calvisi , Vincenzo Cardinale

Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance.

Cellular and molecular gastroenterology and hepatology

Avec: Jiaye Liu , Pengfei Li , Ling Wang , Meng Li , Zhouhong Ge , Lisanne Noordam , Ruby Lieshout , Monique M A Verstegen , Buyun Ma , Junhong Su , Qin Yang , Ruyi Zhang , Guoying Zhou , Lucia Campos Carrascosa , Dave Sprengers , Jan N M IJzermans , Ron Smits , Jaap Kwekkeboom , Luc J W van der Laan , Maikel P Peppelenbosch , Qiuwei Pan , Wanlu Cao

Precancerous liver diseases do not cause increased mutagenesis in liver stem cells.

Communications biology

Avec: Luan Nguyen , Myrthe Jager , Ruby Lieshout , Petra E de Ruiter , Mauro D Locati , Nicolle Besselink , Bastiaan van der Roest , Roel Janssen , Sander Boymans , Jeroen de Jonge , Jan N M IJzermans , Michail Doukas , Monique M A Verstegen , Ruben van Boxtel , Luc J W van der Laan , Edwin Cuppen , Ewart Kuijk

Hepatobiliary tumor organoids for personalized medicine: a multicenter view on establishment, limitations, and future directions.

Cancer cell

Avec: Gilles S van Tienderen , Ling Li , Laura Broutier , Yoshimasa Saito , Patricia Inacio , Meritxell Huch , Florin M Selaru , Luc J W van der Laan , Monique M A Verstegen

The current status of stem cell-based therapies during ex vivo graft perfusion: An integrated review of four organs.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Avec: Stefan H Luijmes , Monique M A Verstegen , Martin J Hoogduijn , Leonard Seghers , Robert C Minnee , Edris A F Mahtab , Yannick J H J Taverne , Marlies E J Reinders , Luc J W van der Laan , Jeroen de Jonge

Label-Free Imaging Analysis of Patient-Derived Cholangiocarcinoma Organoids after Sorafenib Treatment.

Cells

Avec: Michael Koch , Sandra Nickel , Ruby Lieshout , Susanna M Lissek , Martina Leskova , Luc J W van der Laan , Monique M A Verstegen , Bruno Christ , Francesco Pampaloni

Recreating Tumour Complexity in a Dish: Organoid Models to Study Liver Cancer Cells and their Extracellular Environment.

Cancers

Avec: Gilles S van Tienderen , Bas Groot Koerkamp , Jan N M IJzermans , Luc J W van der Laan , Monique M A Verstegen

Prime editing for functional repair in patient-derived disease models.

Nature communications

Avec: Imre F Schene , Indi P Joore , Rurika Oka , Michal Mokry , Anke H M van Vugt , Ruben van Boxtel , Hubert P J van der Doef , Luc J W van der Laan , Monique M A Verstegen , Peter M van Hasselt , Edward E S Nieuwenhuis , Sabine A Fuchs

Rescue of chloride and bicarbonate transport by elexacaftor-ivacaftor-tezacaftor in organoid-derived CF intestinal and cholangiocyte monolayers.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Avec: Marcel J C Bijvelds , Floris J M Roos , Kelly F Meijsen , Henk P Roest , Monique M A Verstegen , Hettie M Janssens , Luc J W van der Laan , Hugo R de Jonge

Modelling metastatic colonization of cholangiocarcinoma organoids in decellularized lung and lymph nodes.

Frontiers in oncology

Avec: Gilles S van Tienderen , Marije E A van Beek , Ivo J Schurink , Oskar Rosmark , Henk P Roest , Jantine Tieleman , Jeroen Demmers , Iain Muntz , James Conboy , Gunilla Westergren-Thorsson , Gijsje Koenderink , Luc Jw van der Laan , Monique M A Verstegen

Emerging organoid-immune co-culture models for cancer research: from oncoimmunology to personalized immunotherapies.

Journal for immunotherapy of cancer

Avec: Luc Magré , Monique M A Verstegen , Sonja Buschow , Luc J W van der Laan , Maikel Peppelenbosch , Jyaysi Desai

Scaffolds obtained from decellularized human extrahepatic bile ducts support organoids to establish functional biliary tissue in a dish.

Biotechnology and bioengineering

Avec: Jorke Willemse , Floris J M Roos , Iris J Voogt , Ivo J Schurink , Marcel Bijvelds , Hugo R de Jonge , Luc J W van der Laan , Jeroen de Jonge , Monique M A Verstegen

Human Bile Contains Cholangiocyte Organoid-Initiating Cells Which Expand as Functional Cholangiocytes in Non-canonical Wnt Stimulating Conditions.

Frontiers in cell and developmental biology

Avec: Floris J M Roos , Monique M A Verstegen , Laura Muñoz Albarinos , Henk P Roest , Jan-Werner Poley , Geert W M Tetteroo , Jan N M IJzermans , Luc J W van der Laan

Impact of hypoxia and AMPK on CFTR-mediated bicarbonate secretion in human cholangiocyte organoids.

American journal of physiology. Gastrointestinal and liver physiology

Avec: Floris J M Roos , Marcel J C Bijvelds , Monique M A Verstegen , Henk P Roest , Herold J Metselaar , Wojciech G Polak , Hugo R de Jonge , Jan N M IJzermans , Luc J W van der Laan

Necroptotic Cell Death in Liver Transplantation and Underlying Diseases: Mechanisms and Clinical Perspective.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Avec: Shaojun Shi , Monique M A Verstegen , Laura Mezzanotte , Jeroen de Jonge , Clemens W G M Löwik , Luc J W van der Laan

Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids.

Cellular and molecular gastroenterology and hepatology

Avec: Shaojun Shi , Monique M A Verstegen , Henk P Roest , Arif I Ardisasmita , Wanlu Cao , Floris J M Roos , Petra E de Ruiter , Marije Niemeijer , Qiuwei Pan , Jan N M IJzermans , Luc J W van der Laan

Recapitulating hepatitis E virus-host interactions and facilitating antiviral drug discovery in human liver-derived organoids.

Science advances

Avec: Pengfei Li , Yunlong Li , Yijin Wang , Jiaye Liu , Marla Lavrijsen , Yang Li , Ruyi Zhang , Monique M A Verstegen , Yining Wang , Tian-Cheng Li , Zhongren Ma , Denis E Kainov , Marco J Bruno , Robert A de Man , Luc J W van der Laan , Maikel P Peppelenbosch , Qiuwei Pan

Design by Nature: Emerging Applications of Native Liver Extracellular Matrix for Cholangiocyte Organoid-Based Regenerative Medicine.

Bioengineering (Basel, Switzerland)

Avec: Jorke Willemse , Luc J W van der Laan , Jeroen de Jonge , Monique M A Verstegen

Scalable Production of Size-Controlled Cholangiocyte and Cholangiocarcinoma Organoids within Liver Extracellular Matrix-Containing Microcapsules.

Cells

Avec: Gilles S van Tienderen , Jorke Willemse , Bas van Loo , Eline V A van Hengel , Jeroen de Jonge , Luc J W van der Laan , Jeroen Leijten , Monique M A Verstegen

Modeling bile duct ischemia and reoxygenation injury in human cholangiocyte organoids for screening of novel cholangio-protective agents.

EBioMedicine

Avec: Shaojun Shi , Henk P Roest , Thierry P P van den Bosch , Marcel J C Bijvelds , Markus U Boehnert , Jeroen de Jonge , Sven O Dekker , Antoine A F de Vries , Hugo R de Jonge , Monique M A Verstegen , Luc J W van der Laan

Réseau de co-auteurs

Luc J W van der Laan 21 collaborations

Jeroen de Jonge 7 collaborations

Jan N M IJzermans 6 collaborations

Henk P Roest 6 collaborations

Floris J M Roos 5 collaborations

Qiuwei Pan 4 collaborations

Ruby Lieshout 4 collaborations

Gilles S van Tienderen 4 collaborations

Hugo R de Jonge 4 collaborations

Pengfei Li 3 collaborations

Petra E de Ruiter 3 collaborations

Maikel P Peppelenbosch 3 collaborations

Marcel J C Bijvelds 3 collaborations

Jorke Willemse 3 collaborations

Shaojun Shi 3 collaborations

Yining Wang 2 collaborations

Jiaye Liu 2 collaborations

Ruyi Zhang 2 collaborations

Wanlu Cao 2 collaborations

Ruben van Boxtel 2 collaborations

Ivo J Schurink 2 collaborations

Manon de Krijger 1 collaboration

Thijmen Visseren 1 collaboration

Manon E Wildenberg 1 collaboration

Gerrit K J Hooijer 1 collaboration

Wouter J de Jonge 1 collaboration

Joanne Verheij 1 collaboration

Cyriel Y Ponsioen 1 collaboration

Sunrui Chen 1 collaboration

Yuebang Yin 1 collaboration

Silvestre Vicent 1 collaboration

Anna Saborowski 1 collaboration

Chiara Raggi 1 collaboration

Stefania Recalcati 1 collaboration

Pietro Invernizzi 1 collaboration

Domenico Alvaro 1 collaboration

Diego F Calvisi 1 collaboration

Vincenzo Cardinale 1 collaboration

Ling Wang 1 collaboration

Meng Li 1 collaboration

Zhouhong Ge 1 collaboration

Lisanne Noordam 1 collaboration

Buyun Ma 1 collaboration

Junhong Su 1 collaboration

Qin Yang 1 collaboration

Guoying Zhou 1 collaboration

Lucia Campos Carrascosa 1 collaboration

Dave Sprengers 1 collaboration

Ron Smits 1 collaboration

Jaap Kwekkeboom 1 collaboration

Luan Nguyen 1 collaboration

Myrthe Jager 1 collaboration

Mauro D Locati 1 collaboration

Nicolle Besselink 1 collaboration

Bastiaan van der Roest 1 collaboration

Roel Janssen 1 collaboration

Sander Boymans 1 collaboration

Michail Doukas 1 collaboration

Edwin Cuppen 1 collaboration

Ewart Kuijk 1 collaboration

Ling Li 1 collaboration

Laura Broutier 1 collaboration

Yoshimasa Saito 1 collaboration

Patricia Inacio 1 collaboration

Meritxell Huch 1 collaboration

Florin M Selaru 1 collaboration

Stefan H Luijmes 1 collaboration

Martin J Hoogduijn 1 collaboration

Leonard Seghers 1 collaboration

Robert C Minnee 1 collaboration

Edris A F Mahtab 1 collaboration

Yannick J H J Taverne 1 collaboration

Marlies E J Reinders 1 collaboration

Michael Koch 1 collaboration

Sandra Nickel 1 collaboration

Susanna M Lissek 1 collaboration

Martina Leskova 1 collaboration

Bruno Christ 1 collaboration

Francesco Pampaloni 1 collaboration

Bas Groot Koerkamp 1 collaboration

Imre F Schene 1 collaboration

Indi P Joore 1 collaboration

Rurika Oka 1 collaboration

Michal Mokry 1 collaboration

Anke H M van Vugt 1 collaboration

Hubert P J van der Doef 1 collaboration

Peter M van Hasselt 1 collaboration

Edward E S Nieuwenhuis 1 collaboration

Sabine A Fuchs 1 collaboration

Kelly F Meijsen 1 collaboration

Hettie M Janssens 1 collaboration

Marije E A van Beek 1 collaboration

Oskar Rosmark 1 collaboration

Jantine Tieleman 1 collaboration

Jeroen Demmers 1 collaboration

Iain Muntz 1 collaboration

James Conboy 1 collaboration

Gunilla Westergren-Thorsson 1 collaboration

Gijsje Koenderink 1 collaboration

Luc Jw van der Laan 1 collaboration

Luc Magré 1 collaboration

Sonja Buschow 1 collaboration

Maikel Peppelenbosch 1 collaboration

Jyaysi Desai 1 collaboration

Iris J Voogt 1 collaboration

Marcel Bijvelds 1 collaboration

Laura Muñoz Albarinos 1 collaboration

Jan-Werner Poley 1 collaboration

Geert W M Tetteroo 1 collaboration

Herold J Metselaar 1 collaboration

Wojciech G Polak 1 collaboration

Laura Mezzanotte 1 collaboration

Clemens W G M Löwik 1 collaboration

Arif I Ardisasmita 1 collaboration

Marije Niemeijer 1 collaboration

Yunlong Li 1 collaboration

Yijin Wang 1 collaboration

Marla Lavrijsen 1 collaboration

Yang Li 1 collaboration

Tian-Cheng Li 1 collaboration

Zhongren Ma 1 collaboration

Denis E Kainov 1 collaboration

Marco J Bruno 1 collaboration

Robert A de Man 1 collaboration

Bas van Loo 1 collaboration

Eline V A van Hengel 1 collaboration

Jeroen Leijten 1 collaboration

Thierry P P van den Bosch 1 collaboration

Markus U Boehnert 1 collaboration

Sven O Dekker 1 collaboration

Antoine A F de Vries 1 collaboration