Ruby Lieshout

Affiliations

Department of Surgery, Erasmus MC Transplant Institute, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Publications (11)

Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition.

Acta biomaterialia

Avec: Gilles S van Tienderen , Oskar Rosmark , Ruby Lieshout , Jorke Willemse , Floor de Weijer , Linda Elowsson Rendin , Gunilla Westergren-Thorsson , Michail Doukas , Bas Groot Koerkamp , Martin E van Royen , Luc Jw van der Laan , Monique Ma Verstegen

Experimental models to unravel the molecular pathogenesis, cell of origin and stem cell properties of cholangiocarcinoma.

Liver international : official journal of the International Association for the Study of the Liver

Avec: Silvestre Vicent , Ruby Lieshout , Anna Saborowski , Monique M A Verstegen , Chiara Raggi , Stefania Recalcati , Pietro Invernizzi , Luc J W van der Laan , Domenico Alvaro , Diego F Calvisi , Vincenzo Cardinale

Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance.

Cellular and molecular gastroenterology and hepatology

Avec: Jiaye Liu , Pengfei Li , Ling Wang , Meng Li , Zhouhong Ge , Lisanne Noordam , Ruby Lieshout , Monique M A Verstegen , Buyun Ma , Junhong Su , Qin Yang , Ruyi Zhang , Guoying Zhou , Lucia Campos Carrascosa , Dave Sprengers , Jan N M IJzermans , Ron Smits , Jaap Kwekkeboom , Luc J W van der Laan , Maikel P Peppelenbosch , Qiuwei Pan , Wanlu Cao

Precancerous liver diseases do not cause increased mutagenesis in liver stem cells.

Communications biology

Avec: Luan Nguyen , Myrthe Jager , Ruby Lieshout , Petra E de Ruiter , Mauro D Locati , Nicolle Besselink , Bastiaan van der Roest , Roel Janssen , Sander Boymans , Jeroen de Jonge , Jan N M IJzermans , Michail Doukas , Monique M A Verstegen , Ruben van Boxtel , Luc J W van der Laan , Edwin Cuppen , Ewart Kuijk

Label-Free Imaging Analysis of Patient-Derived Cholangiocarcinoma Organoids after Sorafenib Treatment.

Cells

Avec: Michael Koch , Sandra Nickel , Ruby Lieshout , Susanna M Lissek , Martina Leskova , Luc J W van der Laan , Monique M A Verstegen , Bruno Christ , Francesco Pampaloni

Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro.

Clinical and translational medicine

Avec: Floris J M Roos , Haoyu Wu , Jorke Willemse , Ruby Lieshout , Laura A Muñoz Albarinos , Yik-Yang Kan , Jan-Werner Poley , Marco J Bruno , Jeroen de Jonge , Richard Bártfai , Hendrik Marks , Jan N M IJzermans , Monique M A Verstegen , Luc J W van der Laan

Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells.

British journal of cancer

Avec: Guoying Zhou , Ruby Lieshout , Gilles S van Tienderen , Valeska de Ruiter , Martin E van Royen , Patrick P C Boor , Luc Magré , Jyaysi Desai , Kübra Köten , Yik Yang Kan , Zhouhong Ge , Lucia Campos Carrascosa , Cecile Geuijen , Dave Sprengers , Luc J W van der Laan , Monique M A Verstegen , Jaap Kwekkeboom

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth.

Cells

Avec: Meng Li , Ling Wang , Yijin Wang , Shaoshi Zhang , Guoying Zhou , Ruby Lieshout , Buyun Ma , Jiaye Liu , Changbo Qu , Monique M A Verstegen , Dave Sprengers , Jaap Kwekkeboom , Luc J W van der Laan , Wanlu Cao , Maikel P Peppelenbosch , Qiuwei Pan

Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells.

Hepatology (Baltimore, Md.)

Avec: Kerstin Schneeberger , Natalia Sánchez-Romero , Shicheng Ye , Frank G van Steenbeek , Loes A Oosterhoff , Iris Pla Palacin , Chen Chen , Monique E van Wolferen , Gilles van Tienderen , Ruby Lieshout , Haaike Colemonts-Vroninks , Imre Schene , Ruurdtje Hoekstra , Monique M A Verstegen , Luc J W van der Laan , Louis C Penning , Sabine A Fuchs , Hans Clevers , Joery De Kock , Pedro M Baptista , Bart Spee

Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification.

Molecular medicine (Cambridge, Mass.)

Avec: Ruby Lieshout , Alessandra V S Faria , Maikel P Peppelenbosch , Luc J W van der Laan , Monique M A Verstegen , Gwenny M Fuhler

Cholangiocarcinoma cell proliferation is enhanced in primary sclerosing cholangitis: A role for IL-17A.

International journal of cancer

Avec: Ruby Lieshout , Eline J C A Kamp , Monique M A Verstegen , Michail Doukas , Winand N M Dinjens , Kübra Köten , Jan N M IJzermans , Marco J Bruno , Maikel P Peppelenbosch , Luc J W van der Laan , Annemarie C de Vries

Réseau de co-auteurs

Monique M A Verstegen 10 collaborations

Luc J W van der Laan 10 collaborations

Jan N M IJzermans 4 collaborations

Maikel P Peppelenbosch 4 collaborations

Michail Doukas 3 collaborations

Guoying Zhou 3 collaborations

Dave Sprengers 3 collaborations

Jaap Kwekkeboom 3 collaborations

Gilles S van Tienderen 2 collaborations

Jorke Willemse 2 collaborations

Martin E van Royen 2 collaborations

Jiaye Liu 2 collaborations

Ling Wang 2 collaborations

Meng Li 2 collaborations

Zhouhong Ge 2 collaborations

Buyun Ma 2 collaborations

Lucia Campos Carrascosa 2 collaborations

Qiuwei Pan 2 collaborations

Wanlu Cao 2 collaborations

Jeroen de Jonge 2 collaborations

Marco J Bruno 2 collaborations

Kübra Köten 2 collaborations

Oskar Rosmark 1 collaboration

Floor de Weijer 1 collaboration

Linda Elowsson Rendin 1 collaboration

Gunilla Westergren-Thorsson 1 collaboration

Bas Groot Koerkamp 1 collaboration

Luc Jw van der Laan 1 collaboration

Monique Ma Verstegen 1 collaboration

Silvestre Vicent 1 collaboration

Anna Saborowski 1 collaboration

Chiara Raggi 1 collaboration

Stefania Recalcati 1 collaboration

Pietro Invernizzi 1 collaboration

Domenico Alvaro 1 collaboration

Diego F Calvisi 1 collaboration

Vincenzo Cardinale 1 collaboration

Pengfei Li 1 collaboration

Lisanne Noordam 1 collaboration

Junhong Su 1 collaboration

Qin Yang 1 collaboration

Ruyi Zhang 1 collaboration

Ron Smits 1 collaboration

Luan Nguyen 1 collaboration

Myrthe Jager 1 collaboration

Petra E de Ruiter 1 collaboration

Mauro D Locati 1 collaboration

Nicolle Besselink 1 collaboration

Bastiaan van der Roest 1 collaboration

Roel Janssen 1 collaboration

Sander Boymans 1 collaboration

Ruben van Boxtel 1 collaboration

Edwin Cuppen 1 collaboration

Ewart Kuijk 1 collaboration

Michael Koch 1 collaboration

Sandra Nickel 1 collaboration

Susanna M Lissek 1 collaboration

Martina Leskova 1 collaboration

Bruno Christ 1 collaboration

Francesco Pampaloni 1 collaboration

Floris J M Roos 1 collaboration

Haoyu Wu 1 collaboration

Laura A Muñoz Albarinos 1 collaboration

Yik-Yang Kan 1 collaboration

Jan-Werner Poley 1 collaboration

Richard Bártfai 1 collaboration

Hendrik Marks 1 collaboration

Valeska de Ruiter 1 collaboration

Patrick P C Boor 1 collaboration

Luc Magré 1 collaboration

Jyaysi Desai 1 collaboration

Yik Yang Kan 1 collaboration

Cecile Geuijen 1 collaboration

Yijin Wang 1 collaboration

Shaoshi Zhang 1 collaboration

Changbo Qu 1 collaboration

Kerstin Schneeberger 1 collaboration

Natalia Sánchez-Romero 1 collaboration

Shicheng Ye 1 collaboration

Frank G van Steenbeek 1 collaboration

Loes A Oosterhoff 1 collaboration

Iris Pla Palacin 1 collaboration

Chen Chen 1 collaboration

Monique E van Wolferen 1 collaboration

Gilles van Tienderen 1 collaboration

Haaike Colemonts-Vroninks 1 collaboration

Imre Schene 1 collaboration

Ruurdtje Hoekstra 1 collaboration

Louis C Penning 1 collaboration

Sabine A Fuchs 1 collaboration

Hans Clevers 1 collaboration

Joery De Kock 1 collaboration

Pedro M Baptista 1 collaboration

Bart Spee 1 collaboration

Alessandra V S Faria 1 collaboration

Gwenny M Fuhler 1 collaboration

Eline J C A Kamp 1 collaboration

Winand N M Dinjens 1 collaboration

Annemarie C de Vries 1 collaboration