Moritz Treeck

Affiliations

Signalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, UK.

Publications (21)

Characterisation of the Toxoplasma gondii tyrosine transporter and its phosphorylation by the calcium-dependent protein kinase 3.

Molecular microbiology

Avec: Bethan A Wallbank , Caia S Dominicus , Malgorzata Broncel , Nathalie Legrave , Gavin Kelly , James I MacRae , Henry M Staines , Moritz Treeck

A 39-Amino-Acid C-Terminal Truncation of GDV1 Disrupts Sexual Commitment in Plasmodium falciparum.

mSphere

Avec: Marta Tibúrcio , Eva Hitz , Igor Niederwieser , Gavin Kelly , Heledd Davies , Christian Doerig , Oliver Billker , Till S Voss , Moritz Treeck

A positive feedback loop mediates crosstalk between calcium, cyclic nucleotide and lipid signalling in calcium-induced Toxoplasma gondii egress.

PLoS pathogens

Avec: Stephanie D Nofal , Caia Dominicus , Malgorzata Broncel , Nicholas J Katris , Helen R Flynn , Gustavo Arrizabalaga , Cyrille Y Botté , Brandon M Invergo , Moritz Treeck

The

Antimicrobial agents and chemotherapy

Avec: Heledd Davies , Bärbel Bergmann , Philipp Walloch , Cornelius Nerlich , Christian Hansen , Sergio Wittlin , Tobias Spielmann , Moritz Treeck , Eric Beitz

A heterotrimeric complex of Toxoplasma proteins promotes parasite survival in interferon gamma-stimulated human cells.

PLoS biology

Avec: Eloise J Lockyer , Francesca Torelli , Simon Butterworth , Ok-Ryul Song , Steven Howell , Anne Weston , Philip East , Moritz Treeck

Divergent kinase regulates membrane ultrastructure of the

Proceedings of the National Academy of Sciences of the United States of America

Avec: Tsebaot Beraki , Xiaoyu Hu , Malgorzata Broncel , Joanna C Young , William J O'Shaughnessy , Dominika Borek , Moritz Treeck , Michael L Reese

Phosphorylation of

mSphere

Avec: Joanna C Young , Malgorzata Broncel , Helena Teague , Matt R G Russell , Olivia L McGovern , Matt Renshaw , David Frith , Ambrosius P Snijders , Lucy Collinson , Vern B Carruthers , Sarah E Ewald , Moritz Treeck

High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription.

Cell host & microbe

Avec: Simon Butterworth , Kristina Kordova , Sambamurthy Chandrasekaran , Kaitlin K Thomas , Francesca Torelli , Eloise J Lockyer , Amelia Edwards , Robert Goldstone , Anita A Koshy , Moritz Treeck

Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in

eLife

Avec: Alex W Chan , Malgorzata Broncel , Eden Yifrach , Nicole R Haseley , Sundeep Chakladar , Elena Andree , Alice L Herneisen , Emily Shortt , Moritz Treeck , Sebastian Lourido

A plasma membrane localized protein phosphatase in Toxoplasma gondii, PPM5C, regulates attachment to host cells.

Scientific reports

Avec: Chunlin Yang , Malgorzata Broncel , Caia Dominicus , Emily Sampson , William J Blakely , Moritz Treeck , Gustavo Arrizabalaga

Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in

bioRxiv : the preprint server for biology

Avec: Alex W Chan , Malgorzata Broncel , Eden Yifrach , Nicole Haseley , Sundeep Chakladar , Elena Andree , Alice L Herneisen , Emily Shortt , Moritz Treeck , Sebastian Lourido

Expression of the MSPDBL2 antigen in a discrete subset of

mBio

Avec: Aline Freville , Lindsay B Stewart , Kevin K A Tetteh , Moritz Treeck , Alfred Cortes , Till S Voss , Sarah J Tarr , David A Baker , David J Conway

PfHDAC1 is an essential regulator of

mBio

Avec: Abhishek Kanyal , Bhagyashree Deshmukh , Heledd Davies , D V Mamatharani , Dilsha Farheen , Moritz Treeck , Krishanpal Karmodiya

Label-Based Mass Spectrometry Approaches for Robust Quantification of the Phosphoproteome and Total Proteome in Toxoplasma gondii.

Methods in molecular biology (Clifton, N.J.)

Avec: Malgorzata Broncel , Moritz Treeck

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery.

PLoS biology

Avec: Avnish Patel , Abigail J Perrin , Helen R Flynn , Claudine Bisson , Chrislaine Withers-Martinez , Moritz Treeck , Christian Flueck , Giuseppe Nicastro , Stephen R Martin , Andres Ramos , Tim W Gilberger , Ambrosius P Snijders , Michael J Blackman , David A Baker

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice.

Nature communications

Avec: Joanna Young , Caia Dominicus , Jeanette Wagener , Simon Butterworth , Xingda Ye , Gavin Kelly , Merav Ordan , Becky Saunders , Rachael Instrell , Michael Howell , Aengus Stewart , Moritz Treeck

An exported kinase family mediates species-specific erythrocyte remodelling and virulence in human malaria.

Nature microbiology

Avec: Heledd Davies , Hugo Belda , Malgorzata Broncel , Xingda Ye , Claudine Bisson , Viola Introini , Dominique Dorin-Semblat , Jean-Philippe Semblat , Marta Tibúrcio , Benoit Gamain , Myrsini Kaforou , Moritz Treeck

Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction.

PLoS pathogens

Avec: Simon Butterworth , Francesca Torelli , Eloise J Lockyer , Jeanette Wagener , Ok-Ryul Song , Malgorzata Broncel , Matt R G Russell , Aline Cristina A Moreira-Souza , Joanna C Young , Moritz Treeck

PerTurboID, a targeted in situ method reveals the impact of kinase deletion on its local protein environment in the cytoadhesion complex of malaria-causing parasites.

eLife

Avec: Heledd Davies , Hugo Belda , Malgorzata Broncel , Jill Dalimot , Moritz Treeck

A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions.

Malaria journal

Avec: Rameswara R Segireddy , Hugo Belda , Annie S P Yang , Kirsten Dundas , Julia Knoeckel , Francis Galaway , Laura Wood , Doris Quinkert , Ellen Knuepfer , Moritz Treeck , Gavin J Wright , Alexander D Douglas

The substrate quality of CK2 target sites has a determinant role on their function and evolution.

Cell systems

Avec: David Bradley , Chantal Garand , Hugo Belda , Isabelle Gagnon-Arsenault , Moritz Treeck , Sabine Elowe , Christian R Landry

Réseau de co-auteurs

Malgorzata Broncel 11 collaborations

Heledd Davies 5 collaborations

Simon Butterworth 4 collaborations

Hugo Belda 4 collaborations

Gavin Kelly 3 collaborations

Caia Dominicus 3 collaborations

Eloise J Lockyer 3 collaborations

Francesca Torelli 3 collaborations

Joanna C Young 3 collaborations

Marta Tibúrcio 2 collaborations

Till S Voss 2 collaborations

Helen R Flynn 2 collaborations

Gustavo Arrizabalaga 2 collaborations

Ok-Ryul Song 2 collaborations

Matt R G Russell 2 collaborations

Ambrosius P Snijders 2 collaborations

Alex W Chan 2 collaborations

Eden Yifrach 2 collaborations

Sundeep Chakladar 2 collaborations

Elena Andree 2 collaborations

Alice L Herneisen 2 collaborations

Emily Shortt 2 collaborations

Sebastian Lourido 2 collaborations

David A Baker 2 collaborations

Claudine Bisson 2 collaborations

Jeanette Wagener 2 collaborations

Xingda Ye 2 collaborations

Bethan A Wallbank 1 collaboration

Caia S Dominicus 1 collaboration

Nathalie Legrave 1 collaboration

James I MacRae 1 collaboration

Henry M Staines 1 collaboration

Eva Hitz 1 collaboration

Igor Niederwieser 1 collaboration

Christian Doerig 1 collaboration

Oliver Billker 1 collaboration

Stephanie D Nofal 1 collaboration

Nicholas J Katris 1 collaboration

Cyrille Y Botté 1 collaboration

Brandon M Invergo 1 collaboration

Bärbel Bergmann 1 collaboration

Philipp Walloch 1 collaboration

Cornelius Nerlich 1 collaboration

Christian Hansen 1 collaboration

Sergio Wittlin 1 collaboration

Tobias Spielmann 1 collaboration

Eric Beitz 1 collaboration

Steven Howell 1 collaboration

Anne Weston 1 collaboration

Philip East 1 collaboration

Tsebaot Beraki 1 collaboration

Xiaoyu Hu 1 collaboration

William J O'Shaughnessy 1 collaboration

Dominika Borek 1 collaboration

Michael L Reese 1 collaboration

Helena Teague 1 collaboration

Olivia L McGovern 1 collaboration

Matt Renshaw 1 collaboration

David Frith 1 collaboration

Lucy Collinson 1 collaboration

Vern B Carruthers 1 collaboration

Sarah E Ewald 1 collaboration

Kristina Kordova 1 collaboration

Sambamurthy Chandrasekaran 1 collaboration

Kaitlin K Thomas 1 collaboration

Amelia Edwards 1 collaboration

Robert Goldstone 1 collaboration

Anita A Koshy 1 collaboration

Nicole R Haseley 1 collaboration

Chunlin Yang 1 collaboration

Emily Sampson 1 collaboration

William J Blakely 1 collaboration

Nicole Haseley 1 collaboration

Aline Freville 1 collaboration

Lindsay B Stewart 1 collaboration

Kevin K A Tetteh 1 collaboration

Alfred Cortes 1 collaboration

Sarah J Tarr 1 collaboration

David J Conway 1 collaboration

Abhishek Kanyal 1 collaboration

Bhagyashree Deshmukh 1 collaboration

D V Mamatharani 1 collaboration

Dilsha Farheen 1 collaboration

Krishanpal Karmodiya 1 collaboration

Avnish Patel 1 collaboration

Abigail J Perrin 1 collaboration

Chrislaine Withers-Martinez 1 collaboration

Christian Flueck 1 collaboration

Giuseppe Nicastro 1 collaboration

Stephen R Martin 1 collaboration

Andres Ramos 1 collaboration

Tim W Gilberger 1 collaboration

Michael J Blackman 1 collaboration

Joanna Young 1 collaboration

Merav Ordan 1 collaboration

Becky Saunders 1 collaboration

Rachael Instrell 1 collaboration

Michael Howell 1 collaboration

Aengus Stewart 1 collaboration

Viola Introini 1 collaboration

Dominique Dorin-Semblat 1 collaboration

Jean-Philippe Semblat 1 collaboration

Benoit Gamain 1 collaboration

Myrsini Kaforou 1 collaboration

Aline Cristina A Moreira-Souza 1 collaboration

Jill Dalimot 1 collaboration

Rameswara R Segireddy 1 collaboration

Annie S P Yang 1 collaboration

Kirsten Dundas 1 collaboration

Julia Knoeckel 1 collaboration

Francis Galaway 1 collaboration

Laura Wood 1 collaboration

Doris Quinkert 1 collaboration

Ellen Knuepfer 1 collaboration

Gavin J Wright 1 collaboration

Alexander D Douglas 1 collaboration

David Bradley 1 collaboration

Chantal Garand 1 collaboration

Isabelle Gagnon-Arsenault 1 collaboration

Sabine Elowe 1 collaboration

Christian R Landry 1 collaboration