Eric Beitz

Affiliations

Department of Pharmaceutical and Medicinal Chemistry, Christian-Albrechts-University, Kiel, Germany.

ORCID: 0000-0001-5912-6626

Publications (23)

Structure memes: Intuitive visualization of sequence logo and subfamily logo information in a 3D protein-structural context.

Proteins

Avec: Eric Beitz

Addressing the Intracellular Vestibule of the Plasmodial Lactate Transporter PfFNT by p-Substituted Inhibitors Amplifies In Vitro Activity.

Journal of medicinal chemistry

Avec: Cornelius Nerlich , Finn Tiedjens , Robin Hertel , Björn Henke , Susan Häuer , Lea S Panitzsch , Kerrin Hansen , Ole Franck , Antonio Mete , Didier Leroy , Dennis Schade , Christian Peifer , Stefan Hannus , Frank Becker , Sergio Wittlin , Tobias Spielmann , Eric Beitz

A Fluorescence-Based Method to Measure ADP/ATP Exchange of Recombinant Adenine Nucleotide Translocase in Liposomes.

Biomolecules

Avec: Jürgen Kreiter , Eric Beitz , Elena E Pohl

Lactic Acid Permeability of Aquaporin-9 Enables Cytoplasmic Lactate Accumulation via an Ion Trap.

Life (Basel, Switzerland)

Avec: Katharina Geistlinger , Jana D R Schmidt , Eric Beitz

Cell-free production of fluorescent proteins for the discovery of novel ribosome-targeting antibiotics.

Journal of microbiological methods

Avec: Bastian Höger , Christian Peifer , Eric Beitz

Methylthiosulfonate-Based Cysteine Modifiers as Alternative Inhibitors of Mercurial-Sensitive Aquaporins.

Cells

Avec: Katrin Jeuken , Emmi Jaeger , Emily Matthews , Eric Beitz

Introduction of Scaffold Nitrogen Atoms Renders Inhibitors of the Malarial l-Lactate Transporter, PfFNT, Effective against the Gly107Ser Resistance Mutation.

Journal of medicinal chemistry

Avec: Philipp Walloch , Björn Henke , Susan Häuer , Bärbel Bergmann , Tobias Spielmann , Eric Beitz

Transmembrane Facilitation of Lactate/H

Membranes

Avec: Annika Bader , Eric Beitz

Yeast Solutions and Hyperpolarization Enable Real-Time Observation of Metabolized Substrates Even at Natural Abundance.

Analytical chemistry

Avec: Josh P Peters , Charbel Assaf , Farhad Haj Mohamad , Eric Beitz , Sanjay Tiwari , Konrad Aden , Jan-Bernd Hövener , Andrey N Pravdivtsev

The Ionophores CCCP and Gramicidin but Not Nigericin Inhibit

Cells

Avec: Lea Madlen Petersen , Eric Beitz

Formate-nitrite transporters carrying nonprotonatable amide amino acids instead of a central histidine maintain pH-dependent transport.

The Journal of biological chemistry

Avec: Folknand Helmstetter , Philipp Arnold , Bastian Höger , Lea Madlen Petersen , Eric Beitz

Mutational widening of constrictions in a formate-nitrite/H

The Journal of biological chemistry

Avec: Jana D R Schmidt , Eric Beitz

Cell-Free and Yeast-Based Production of the Malarial Lactate Transporter, PfFNT, Delivers Comparable Yield and Protein Quality.

Frontiers in pharmacology

Avec: Philipp Hajek , Annika Bader , Folknand Helmstetter , Björn Henke , Philipp Arnold , Eric Beitz

Basigin drives intracellular accumulation of l-lactate by harvesting protons and substrate anions.

PloS one

Avec: Anna-Lena Köpnick , Annika Jansen , Katharina Geistlinger , Nathan Hugo Epalle , Eric Beitz

Degraded Arabinogalactans and Their Binding Properties to Cancer-Associated Human Galectins.

International journal of molecular sciences

Avec: Lukas Pfeifer , Alexander Baumann , Lea Madlen Petersen , Bastian Höger , Eric Beitz , Birgit Classen

Cysteine 159 delineates a hinge region of the alternating access monocarboxylate transporter 1 and is targeted by cysteine-modifying inhibitors.

The FEBS journal

Avec: Anna-Lena Köpnick , Katharina Geistlinger , Eric Beitz

Aquaporins with lactate/lactic acid permeability at physiological pH conditions.

Biochimie

Avec: Jana D R Schmidt , Philipp Walloch , Bastian Höger , Eric Beitz

Pentafluoro-3-hydroxy-pent-2-en-1-ones Potently Inhibit FNT-Type Lactate Transporters from all Five Human-Pathogenic Plasmodium Species.

ChemMedChem

Avec: Philipp Walloch , Christian Hansen , Till Priegann , Dennis Schade , Eric Beitz

Fluorescence Cross-Correlation Spectroscopy Yields True Affinity and Binding Kinetics of

Pharmaceuticals (Basel, Switzerland)

Avec: Iga Jakobowska , Frank Becker , Stefano Minguzzi , Kerrin Hansen , Björn Henke , Nathan Hugo Epalle , Eric Beitz , Stefan Hannus

Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in

Cells

Avec: Marilina Florio , Angelica Engfors , Patrizia Gena , Jessica Larsson , Alessandro Massaro , Stella Timpka , Martina Kvist Reimer , Per Kjellbom , Eric Beitz , Urban Johanson , Michael Rützler , Giuseppe Calamita

Local Attraction of Substrates and Co-Substrates Enhances Weak Acid and Base Transmembrane Transport.

Biomolecules

Avec: Nathan Hugo Epalle , Eric Beitz

Human monocarboxylate transporters accept and relay protons via the bound substrate for selectivity and activity at physiological pH.

PNAS nexus

Avec: Katharina Geistlinger , Jana D R Schmidt , Eric Beitz

The

Antimicrobial agents and chemotherapy

Avec: Heledd Davies , Bärbel Bergmann , Philipp Walloch , Cornelius Nerlich , Christian Hansen , Sergio Wittlin , Tobias Spielmann , Moritz Treeck , Eric Beitz

Réseau de co-auteurs

Björn Henke 4 collaborations

Katharina Geistlinger 4 collaborations

Jana D R Schmidt 4 collaborations

Bastian Höger 4 collaborations

Philipp Walloch 4 collaborations

Tobias Spielmann 3 collaborations

Lea Madlen Petersen 3 collaborations

Nathan Hugo Epalle 3 collaborations

Cornelius Nerlich 2 collaborations

Susan Häuer 2 collaborations

Kerrin Hansen 2 collaborations

Dennis Schade 2 collaborations

Christian Peifer 2 collaborations

Stefan Hannus 2 collaborations

Frank Becker 2 collaborations

Sergio Wittlin 2 collaborations

Bärbel Bergmann 2 collaborations

Annika Bader 2 collaborations

Folknand Helmstetter 2 collaborations

Philipp Arnold 2 collaborations

Anna-Lena Köpnick 2 collaborations

Christian Hansen 2 collaborations

Finn Tiedjens 1 collaboration

Robin Hertel 1 collaboration

Lea S Panitzsch 1 collaboration

Ole Franck 1 collaboration

Antonio Mete 1 collaboration

Didier Leroy 1 collaboration

Jürgen Kreiter 1 collaboration

Elena E Pohl 1 collaboration

Katrin Jeuken 1 collaboration

Emmi Jaeger 1 collaboration

Emily Matthews 1 collaboration

Josh P Peters 1 collaboration

Charbel Assaf 1 collaboration

Farhad Haj Mohamad 1 collaboration

Sanjay Tiwari 1 collaboration

Konrad Aden 1 collaboration

Jan-Bernd Hövener 1 collaboration

Andrey N Pravdivtsev 1 collaboration

Philipp Hajek 1 collaboration

Annika Jansen 1 collaboration

Lukas Pfeifer 1 collaboration

Alexander Baumann 1 collaboration

Birgit Classen 1 collaboration

Till Priegann 1 collaboration

Iga Jakobowska 1 collaboration

Stefano Minguzzi 1 collaboration

Marilina Florio 1 collaboration

Angelica Engfors 1 collaboration

Patrizia Gena 1 collaboration

Jessica Larsson 1 collaboration

Alessandro Massaro 1 collaboration

Stella Timpka 1 collaboration

Martina Kvist Reimer 1 collaboration

Per Kjellbom 1 collaboration

Urban Johanson 1 collaboration

Michael Rützler 1 collaboration

Giuseppe Calamita 1 collaboration

Heledd Davies 1 collaboration

Moritz Treeck 1 collaboration