Neil Brewis

Affiliations

F-star Therapeutics Ltd., Cambridge, UK.

Publications (7)

Antibodies as drugs-a Keystone Symposia report.

Annals of the New York Academy of Sciences

Avec: Jennifer Cable , Erica Ollmann Saphire , Adrian C Hayday , Timothy D Wiltshire , Jarrod J Mousa , David P Humphreys , Esther C W Breij , Pierre Bruhns , Matteo Broketa , Genta Furuya , Blake M Hauser , Matthieu Mahévas , Andrea Carfi , Tineke Cantaert , Peter D Kwong , Prabhanshu Tripathi , Jonathan H Davis , Neil Brewis , Bruce A Keyt , Felix L Fennemann , Vincent Dussupt , Arvind Sivasubramanian , Philip M Kim , Reda Rawi , Eve Richardson , Daniel Leventhal , Rachael M Wolters , Cecile A W Geuijen , Matthew A Sleeman , Niccolo Pengo , Francesca Rose Donnellan

FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Matthew A Lakins , Alexander Koers , Raffaella Giambalvo , Jose Munoz-Olaya , Robert Hughes , Emma Goodman , Sylwia Marshall , Francisca Wollerton , Sarah Batey , Daniel Gliddon , Mihriban Tuna , Neil Brewis

M9657 is a bispecific tumor-targeted anti-CD137 agonist that induces MSLN-dependent antitumor immunity without liver inflammation.

Cancer immunology research

Avec: Chunxiao Xu , Xueyuan Zhou , Lindsay Webb , Sireesha Yalavarthi , Wenxin Zheng , Somdutta Saha , Rene Schweickhardt , Maria Soloviev , Molly H Jenkins , Susanne Brandstetter , Natalya Belousova , Marat Alimzhanov , Brian Rabinovich , Amit M Deshpande , Neil Brewis , Laura Helming

CD137/OX40 Bispecific Antibody Induces Potent Antitumor Activity that Is Dependent on Target Coengagement.

Cancer immunology research

Avec: Miguel Gaspar , John Pravin , Leonor Rodrigues , Sandra Uhlenbroich , Katy L Everett , Francisca Wollerton , Michelle Morrow , Mihriban Tuna , Neil Brewis

FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor Activity.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Matthew Kraman , Mustapha Faroudi , Natalie L Allen , Katarzyna Kmiecik , Daniel Gliddon , Claire Seal , Alexander Koers , Mateusz M Wydro , Sarah Batey , Julia Winnewisser , Lesley Young , Mihriban Tuna , Jacqueline Doody , Michelle Morrow , Neil Brewis

A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Timothy A Yap , Patricia M LoRusso , Deborah J Wong , Siwen Hu-Lieskovan , Kyriakos P Papadopoulos , Josefin-Beate Holz , Urszula Grabowska , Cristian Gradinaru , Kin-Mei Leung , Sylwia Marshall , Claire S Reader , Roslin Russell , Richard C A Sainson , Claire J Seal , Christopher J Shepherd , Fiona Germaschewski , Daniel Gliddon , Omer Stern , Lesley Young , Neil Brewis , Louis Kayitalire , Michelle Morrow

IFN-γ production by functionally reprogrammed Treg cells promotes anti-tumor efficacy of OX40/CD137 bispecific agonist therapy.

Cancer research communications

Avec: Charlotte J Imianowski , Paula Kuo , Sarah K Whiteside , Teresa von Linde , Alexander J Wesolowski , Alberto G Conti , Alexander C Evans , Tarrion Baird , Benjamin I Morris , Nicole E Fletcher , Jie Yang , Edmund Poon , Matthew A Lakins , Masahiro Yamamoto , Neil Brewis , Michelle Morrow , Rahul Roychoudhuri

Réseau de co-auteurs

Michelle Morrow 4 collaborations

Daniel Gliddon 3 collaborations

Mihriban Tuna 3 collaborations

Matthew A Lakins 2 collaborations

Alexander Koers 2 collaborations

Sylwia Marshall 2 collaborations

Francisca Wollerton 2 collaborations

Sarah Batey 2 collaborations

Lesley Young 2 collaborations

Jennifer Cable 1 collaboration

Erica Ollmann Saphire 1 collaboration

Adrian C Hayday 1 collaboration

Timothy D Wiltshire 1 collaboration

Jarrod J Mousa 1 collaboration

David P Humphreys 1 collaboration

Esther C W Breij 1 collaboration

Pierre Bruhns 1 collaboration

Matteo Broketa 1 collaboration

Genta Furuya 1 collaboration

Blake M Hauser 1 collaboration

Matthieu Mahévas 1 collaboration

Andrea Carfi 1 collaboration

Tineke Cantaert 1 collaboration

Peter D Kwong 1 collaboration

Prabhanshu Tripathi 1 collaboration

Jonathan H Davis 1 collaboration

Bruce A Keyt 1 collaboration

Felix L Fennemann 1 collaboration

Vincent Dussupt 1 collaboration

Arvind Sivasubramanian 1 collaboration

Philip M Kim 1 collaboration

Reda Rawi 1 collaboration

Eve Richardson 1 collaboration

Daniel Leventhal 1 collaboration

Rachael M Wolters 1 collaboration

Cecile A W Geuijen 1 collaboration

Matthew A Sleeman 1 collaboration

Niccolo Pengo 1 collaboration

Francesca Rose Donnellan 1 collaboration

Raffaella Giambalvo 1 collaboration

Jose Munoz-Olaya 1 collaboration

Robert Hughes 1 collaboration

Emma Goodman 1 collaboration

Chunxiao Xu 1 collaboration

Xueyuan Zhou 1 collaboration

Lindsay Webb 1 collaboration

Sireesha Yalavarthi 1 collaboration

Wenxin Zheng 1 collaboration

Somdutta Saha 1 collaboration

Rene Schweickhardt 1 collaboration

Maria Soloviev 1 collaboration

Molly H Jenkins 1 collaboration

Susanne Brandstetter 1 collaboration

Natalya Belousova 1 collaboration

Marat Alimzhanov 1 collaboration

Brian Rabinovich 1 collaboration

Amit M Deshpande 1 collaboration

Laura Helming 1 collaboration

Miguel Gaspar 1 collaboration

John Pravin 1 collaboration

Leonor Rodrigues 1 collaboration

Sandra Uhlenbroich 1 collaboration

Katy L Everett 1 collaboration

Matthew Kraman 1 collaboration

Mustapha Faroudi 1 collaboration

Natalie L Allen 1 collaboration

Katarzyna Kmiecik 1 collaboration

Claire Seal 1 collaboration

Mateusz M Wydro 1 collaboration

Julia Winnewisser 1 collaboration

Jacqueline Doody 1 collaboration

Timothy A Yap 1 collaboration

Patricia M LoRusso 1 collaboration

Deborah J Wong 1 collaboration

Siwen Hu-Lieskovan 1 collaboration

Kyriakos P Papadopoulos 1 collaboration

Josefin-Beate Holz 1 collaboration

Urszula Grabowska 1 collaboration

Cristian Gradinaru 1 collaboration

Kin-Mei Leung 1 collaboration

Claire S Reader 1 collaboration

Roslin Russell 1 collaboration

Richard C A Sainson 1 collaboration

Claire J Seal 1 collaboration

Christopher J Shepherd 1 collaboration

Fiona Germaschewski 1 collaboration

Omer Stern 1 collaboration

Louis Kayitalire 1 collaboration

Charlotte J Imianowski 1 collaboration

Paula Kuo 1 collaboration

Sarah K Whiteside 1 collaboration

Teresa von Linde 1 collaboration

Alexander J Wesolowski 1 collaboration

Alberto G Conti 1 collaboration

Alexander C Evans 1 collaboration

Tarrion Baird 1 collaboration

Benjamin I Morris 1 collaboration

Nicole E Fletcher 1 collaboration

Jie Yang 1 collaboration

Edmund Poon 1 collaboration

Masahiro Yamamoto 1 collaboration

Rahul Roychoudhuri 1 collaboration