Pablo Guardado-Calvo

Affiliations

Institut Pasteur, Structural Virology Unit, and CNRS UMR 3569, Paris, France. Electronic address: guardado@pasteur.fr.

Publications (22)

The surface glycoproteins of hantaviruses.

Current opinion in virology

Avec: Pablo Guardado-Calvo , Félix A Rey

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.

Science translational medicine

Avec: Eva Mittler , Alexandra Serris , Emma S Esterman , Catalina Florez , Laura C Polanco , Cecilia M O'Brien , Megan M Slough , Janne Tynell , Remigius Gröning , Yan Sun , Dafna M Abelson , Anna Z Wec , Denise Haslwanter , Markus Keller , Chunyan Ye , Russel R Bakken , Rohit K Jangra , John M Dye , Clas Ahlm , C Garrett Rappazzo , Rainer G Ulrich , Larry Zeitlin , James C Geoghegan , Steven B Bradfute , Simone Sidoli , Mattias N E Forsell , Tomas Strandin , Felix A Rey , Andrew S Herbert , Laura M Walker , Kartik Chandran , Pablo Guardado-Calvo

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

The Journal of experimental medicine

Avec: Cyril Planchais , Ignacio Fernández , Timothée Bruel , Guilherme Dias de Melo , Matthieu Prot , Maxime Beretta , Pablo Guardado-Calvo , Jérémy Dufloo , Luis M Molinos-Albert , Marija Backovic , Jeanne Chiaravalli , Emilie Giraud , Benjamin Vesin , Laurine Conquet , Ludivine Grzelak , Delphine Planas , Isabelle Staropoli , Florence Guivel-Benhassine , Thierry Hieu , Mikaël Boullé , Minerva Cervantes-Gonzalez , Marie-Noëlle Ungeheuer , Pierre Charneau , Sylvie van der Werf , Fabrice Agou , Auteur inconnu , Auteur inconnu , Jordan D Dimitrov , Etienne Simon-Lorière , Hervé Bourhy , Xavier Montagutelli , Félix A Rey , Olivier Schwartz , Hugo Mouquet

Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.

Cell reports

Avec: Jan Hellert , Andrea Aebischer , Ahmed Haouz , Pablo Guardado-Calvo , Sven Reiche , Martin Beer , Félix A Rey

Production and Purification of Hantavirus Glycoproteins in Drosophila melanogaster S2 Cells.

Methods in molecular biology (Clifton, N.J.)

Avec: Annalisa Meola , Pablo Guardado-Calvo

MPXV Infection Stimulates a More Robust and Durable Neutralizing Antibody Response Compared to MVA-BN Vaccination.

The Journal of infectious diseases

Avec: Christopher N Selverian , Stephanie R Monticelli , Yakin M Jaleta , Gorka Lasso , Megan E DeMouth , Annalisa Meola , Jacob Berrigan , Thomas G Batchelor , Leandro Battini , Pablo Guardado-Calvo , Andrew S Herbert , Kartik Chandran , Eric Meyerowitz , Emily Happy Miller

The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.

Cell

Avec: Arvind Sharma , Xiaokang Zhang , Wanwisa Dejnirattisai , Xinghong Dai , Danyang Gong , Wiyada Wongwiwat , Stéphane Duquerroy , Alexander Rouvinski , Marie-Christine Vaney , Pablo Guardado-Calvo , Ahmed Haouz , Patrick England , Ren Sun , Z Hong Zhou , Juthathip Mongkolsapaya , Gavin R Screaton , Felix A Rey

Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection.

Nature communications

Avec: Megan M Slough , Rong Li , Andrew S Herbert , Gorka Lasso , Ana I Kuehne , Stephanie R Monticelli , Russell R Bakken , Yanan Liu , Agnidipta Ghosh , Alicia M Moreau , Xiankun Zeng , Félix A Rey , Pablo Guardado-Calvo , Steven C Almo , John M Dye , Rohit K Jangra , Zhongde Wang , Kartik Chandran

A Search for Tick-Associated, Bronnoya-like Virus Spillover into Sheep.

Microorganisms

Avec: Bianca Elena Bratuleanu , Cristian Raileanu , Delphine Chrétien , Pablo Guardado-Calvo , Thomas Bigot , Gheorghe Savuta , Sarah Temmam , Marc Eloit

Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2.

iScience

Avec: Cyril Planchais , Ignacio Fernández , Benjamin Chalopin , Timothée Bruel , Pierre Rosenbaum , Maxime Beretta , Jordan D Dimitrov , Laurine Conquet , Flora Donati , Matthieu Prot , Françoise Porrot , Delphine Planas , Isabelle Staropoli , Florence Guivel-Benhassine , Eduard Baquero , Sylvie van der Werf , Ahmed Haouz , Etienne Simon-Lorière , Xavier Montagutelli , Bernard Maillère , Félix A Rey , Pablo Guardado-Calvo , Hervé Nozach , Olivier Schwartz , Hugo Mouquet

Orthobunyavirus spike architecture and recognition by neutralizing antibodies.

Nature communications

Avec: Jan Hellert , Andrea Aebischer , Kerstin Wernike , Ahmed Haouz , Emiliana Brocchi , Sven Reiche , Pablo Guardado-Calvo , Martin Beer , Félix A Rey

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.

Cell

Avec: Alexandra Serris , Robert Stass , Eduardo A Bignon , Nicolás A Muena , Jean-Claude Manuguerra , Rohit K Jangra , Sai Li , Kartik Chandran , Nicole D Tischler , Juha T Huiskonen , Felix A Rey , Pablo Guardado-Calvo

Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.

PLoS biology

Avec: Taylor P Light , Delphine Brun , Pablo Guardado-Calvo , Riccardo Pederzoli , Ahmed Haouz , Frank Neipel , Félix A Rey , Kalina Hristova , Marija Backovic

Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses.

Science translational medicine

Avec: Eva Mittler , Anna Z Wec , Janne Tynell , Pablo Guardado-Calvo , Julia Wigren-Byström , Laura C Polanco , Cecilia M O'Brien , Megan M Slough , Dafna M Abelson , Alexandra Serris , Mrunal Sakharkar , Gerard Pehau-Arnaudet , Russell R Bakken , James C Geoghegan , Rohit K Jangra , Markus Keller , Larry Zeitlin , Olli Vapalahti , Rainer G Ulrich , Zachary A Bornholdt , Clas Ahlm , Felix A Rey , John M Dye , Steven B Bradfute , Tomas Strandin , Andrew S Herbert , Mattias N E Forsell , Laura M Walker , Kartik Chandran

Mechanisms of Tecovirimat Antiviral Activity and Poxvirus Resistance.

Research square

Avec: Riccardo Vernuccio , Alejandro Martínez León , Chetan Poojari , Julian Buchrieser , Christopher Selverian , Yakin Jaleta , Annalisa Meola , Florence Guivel-Benhassine , Françoise Porrot , Ahmed Haouz , Maelenn Chevreuil , Bertrand Raynal , Jason Mercer , Etienne Simon-Loriere , Kartik Chandran , Olivier Schwartz , Jochen Hub , Pablo Guardado-Calvo

Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope.

Journal of immunology research

Avec: Karim Dorgham , Nicolas Pietrancosta , Amel Affoune , Olivier Lucar , Tahar Bouceba , Solenne Chardonnet , Cedric Pionneau , Christophe Piesse , Delphine Sterlin , Pablo Guardado-Calvo , Philippe Karoyan , Patrice Debré , Guy Gorochov , Vincent Vieillard

Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface.

eLife

Avec: Eduardo A Bignon , Amelina Albornoz , Pablo Guardado-Calvo , Félix A Rey , Nicole D Tischler

Multimeric single-domain antibody complexes protect against bunyavirus infections.

eLife

Avec: Paul J Wichgers Schreur , Sandra van de Water , Michiel Harmsen , Erick Bermúdez-Méndez , Dubravka Drabek , Frank Grosveld , Kerstin Wernike , Martin Beer , Andrea Aebischer , Olalekan Daramola , Sara Rodriguez Conde , Karen Brennan , Dorota Kozub , Maiken Søndergaard Kristiansen , Kieran K Mistry , Ziyan Deng , Jan Hellert , Pablo Guardado-Calvo , Félix A Rey , Lucien van Keulen , Jeroen Kortekaas

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.

Science (New York, N.Y.)

Avec: Akaash K Mishra , Jan Hellert , Natalia Freitas , Pablo Guardado-Calvo , Ahmed Haouz , J Maximilian Fels , Daniel P Maurer , Dafna M Abelson , Zachary A Bornholdt , Laura M Walker , Kartik Chandran , François-Loïc Cosset , Jason S McLellan , Felix A Rey

Generation of plasma cells and CD27

Clinical & translational immunology

Avec: Priscilla F Kerkman , Andy Dernstedt , Lalitha Tadala , Eva Mittler , Mirjam Dannborg , Christopher Sundling , Kimia T Maleki , Johanna Tauriainen , Anne Tuiskunen-Bäck , Julia Wigren Byström , Pauline Ocaya , Therese Thunberg , Rohit K Jangra , Gleyder Román-Sosa , Pablo Guardado-Calvo , Felix A Rey , Jonas Klingström , Kartik Chandran , Andrea Puhar , Clas Ahlm , Mattias Ne Forsell

The Viral Class II Membrane Fusion Machinery: Divergent Evolution from an Ancestral Heterodimer.

Viruses

Avec: Pablo Guardado-Calvo , Félix A Rey

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies.

eLife

Avec: Taylor B Engdahl , Elad Binshtein , Rebecca L Brocato , Natalia A Kuzmina , Lucia M Principe , Steven A Kwilas , Robert K Kim , Nathaniel S Chapman , Monique S Porter , Pablo Guardado-Calvo , Félix A Rey , Laura S Handal , Summer M Diaz , Irene A Zagol-Ikapitte , Minh H Tran , W Hayes McDonald , Jens Meiler , Joseph X Reidy , Andrew Trivette , Alexander Bukreyev , Jay W Hooper , James E Crowe

Réseau de co-auteurs

Félix A Rey 11 collaborations

Kartik Chandran 8 collaborations

Ahmed Haouz 7 collaborations

Felix A Rey 6 collaborations

Rohit K Jangra 5 collaborations

Andrew S Herbert 4 collaborations

Jan Hellert 4 collaborations

Eva Mittler 3 collaborations

Alexandra Serris 3 collaborations

Megan M Slough 3 collaborations

Dafna M Abelson 3 collaborations

John M Dye 3 collaborations

Clas Ahlm 3 collaborations

Laura M Walker 3 collaborations

Florence Guivel-Benhassine 3 collaborations

Olivier Schwartz 3 collaborations

Andrea Aebischer 3 collaborations

Martin Beer 3 collaborations

Annalisa Meola 3 collaborations

Laura C Polanco 2 collaborations

Cecilia M O'Brien 2 collaborations

Janne Tynell 2 collaborations

Anna Z Wec 2 collaborations

Markus Keller 2 collaborations

Rainer G Ulrich 2 collaborations

Larry Zeitlin 2 collaborations

James C Geoghegan 2 collaborations

Steven B Bradfute 2 collaborations

Mattias N E Forsell 2 collaborations

Tomas Strandin 2 collaborations

Cyril Planchais 2 collaborations

Ignacio Fernández 2 collaborations

Timothée Bruel 2 collaborations

Matthieu Prot 2 collaborations

Maxime Beretta 2 collaborations

Marija Backovic 2 collaborations

Laurine Conquet 2 collaborations

Delphine Planas 2 collaborations

Isabelle Staropoli 2 collaborations

Sylvie van der Werf 2 collaborations

None None 2 collaborations

Jordan D Dimitrov 2 collaborations

Etienne Simon-Lorière 2 collaborations

Xavier Montagutelli 2 collaborations

Hugo Mouquet 2 collaborations

Sven Reiche 2 collaborations

Stephanie R Monticelli 2 collaborations

Gorka Lasso 2 collaborations

Russell R Bakken 2 collaborations

Françoise Porrot 2 collaborations

Kerstin Wernike 2 collaborations

Eduardo A Bignon 2 collaborations

Nicole D Tischler 2 collaborations

Zachary A Bornholdt 2 collaborations

Emma S Esterman 1 collaboration

Catalina Florez 1 collaboration

Remigius Gröning 1 collaboration

Yan Sun 1 collaboration

Denise Haslwanter 1 collaboration

Chunyan Ye 1 collaboration

Russel R Bakken 1 collaboration

C Garrett Rappazzo 1 collaboration

Simone Sidoli 1 collaboration

Guilherme Dias de Melo 1 collaboration

Jérémy Dufloo 1 collaboration

Luis M Molinos-Albert 1 collaboration

Jeanne Chiaravalli 1 collaboration

Emilie Giraud 1 collaboration

Benjamin Vesin 1 collaboration

Ludivine Grzelak 1 collaboration

Thierry Hieu 1 collaboration

Mikaël Boullé 1 collaboration

Minerva Cervantes-Gonzalez 1 collaboration

Marie-Noëlle Ungeheuer 1 collaboration

Pierre Charneau 1 collaboration

Fabrice Agou 1 collaboration

Hervé Bourhy 1 collaboration

Christopher N Selverian 1 collaboration

Yakin M Jaleta 1 collaboration

Megan E DeMouth 1 collaboration

Jacob Berrigan 1 collaboration

Thomas G Batchelor 1 collaboration

Leandro Battini 1 collaboration

Eric Meyerowitz 1 collaboration

Emily Happy Miller 1 collaboration

Arvind Sharma 1 collaboration

Xiaokang Zhang 1 collaboration

Wanwisa Dejnirattisai 1 collaboration

Xinghong Dai 1 collaboration

Danyang Gong 1 collaboration

Wiyada Wongwiwat 1 collaboration

Stéphane Duquerroy 1 collaboration

Alexander Rouvinski 1 collaboration

Marie-Christine Vaney 1 collaboration

Patrick England 1 collaboration

Ren Sun 1 collaboration

Z Hong Zhou 1 collaboration

Juthathip Mongkolsapaya 1 collaboration

Gavin R Screaton 1 collaboration

Rong Li 1 collaboration

Ana I Kuehne 1 collaboration

Yanan Liu 1 collaboration

Agnidipta Ghosh 1 collaboration

Alicia M Moreau 1 collaboration

Xiankun Zeng 1 collaboration

Steven C Almo 1 collaboration

Zhongde Wang 1 collaboration

Bianca Elena Bratuleanu 1 collaboration

Cristian Raileanu 1 collaboration

Delphine Chrétien 1 collaboration

Thomas Bigot 1 collaboration

Gheorghe Savuta 1 collaboration

Sarah Temmam 1 collaboration

Marc Eloit 1 collaboration

Benjamin Chalopin 1 collaboration

Pierre Rosenbaum 1 collaboration

Flora Donati 1 collaboration

Eduard Baquero 1 collaboration

Bernard Maillère 1 collaboration

Hervé Nozach 1 collaboration

Emiliana Brocchi 1 collaboration

Robert Stass 1 collaboration

Nicolás A Muena 1 collaboration

Jean-Claude Manuguerra 1 collaboration

Sai Li 1 collaboration

Juha T Huiskonen 1 collaboration

Taylor P Light 1 collaboration

Delphine Brun 1 collaboration

Riccardo Pederzoli 1 collaboration

Frank Neipel 1 collaboration

Kalina Hristova 1 collaboration

Julia Wigren-Byström 1 collaboration

Mrunal Sakharkar 1 collaboration

Gerard Pehau-Arnaudet 1 collaboration

Olli Vapalahti 1 collaboration

Riccardo Vernuccio 1 collaboration

Alejandro Martínez León 1 collaboration

Chetan Poojari 1 collaboration

Julian Buchrieser 1 collaboration

Christopher Selverian 1 collaboration

Yakin Jaleta 1 collaboration

Maelenn Chevreuil 1 collaboration

Bertrand Raynal 1 collaboration

Jason Mercer 1 collaboration

Etienne Simon-Loriere 1 collaboration

Jochen Hub 1 collaboration

Karim Dorgham 1 collaboration

Nicolas Pietrancosta 1 collaboration

Amel Affoune 1 collaboration

Olivier Lucar 1 collaboration

Tahar Bouceba 1 collaboration

Solenne Chardonnet 1 collaboration

Cedric Pionneau 1 collaboration

Christophe Piesse 1 collaboration

Delphine Sterlin 1 collaboration

Philippe Karoyan 1 collaboration

Patrice Debré 1 collaboration

Guy Gorochov 1 collaboration

Vincent Vieillard 1 collaboration

Amelina Albornoz 1 collaboration

Paul J Wichgers Schreur 1 collaboration

Sandra van de Water 1 collaboration

Michiel Harmsen 1 collaboration

Erick Bermúdez-Méndez 1 collaboration

Dubravka Drabek 1 collaboration

Frank Grosveld 1 collaboration

Olalekan Daramola 1 collaboration

Sara Rodriguez Conde 1 collaboration

Karen Brennan 1 collaboration

Dorota Kozub 1 collaboration

Maiken Søndergaard Kristiansen 1 collaboration

Kieran K Mistry 1 collaboration

Ziyan Deng 1 collaboration

Lucien van Keulen 1 collaboration

Jeroen Kortekaas 1 collaboration

Akaash K Mishra 1 collaboration

Natalia Freitas 1 collaboration

J Maximilian Fels 1 collaboration

Daniel P Maurer 1 collaboration

François-Loïc Cosset 1 collaboration

Jason S McLellan 1 collaboration

Priscilla F Kerkman 1 collaboration

Andy Dernstedt 1 collaboration

Lalitha Tadala 1 collaboration

Mirjam Dannborg 1 collaboration

Christopher Sundling 1 collaboration

Kimia T Maleki 1 collaboration

Johanna Tauriainen 1 collaboration

Anne Tuiskunen-Bäck 1 collaboration

Julia Wigren Byström 1 collaboration

Pauline Ocaya 1 collaboration

Therese Thunberg 1 collaboration

Gleyder Román-Sosa 1 collaboration

Jonas Klingström 1 collaboration

Andrea Puhar 1 collaboration

Mattias Ne Forsell 1 collaboration

Taylor B Engdahl 1 collaboration

Elad Binshtein 1 collaboration

Rebecca L Brocato 1 collaboration

Natalia A Kuzmina 1 collaboration

Lucia M Principe 1 collaboration

Steven A Kwilas 1 collaboration

Robert K Kim 1 collaboration

Nathaniel S Chapman 1 collaboration

Monique S Porter 1 collaboration

Laura S Handal 1 collaboration

Summer M Diaz 1 collaboration

Irene A Zagol-Ikapitte 1 collaboration

Minh H Tran 1 collaboration

W Hayes McDonald 1 collaboration

Jens Meiler 1 collaboration

Joseph X Reidy 1 collaboration

Andrew Trivette 1 collaboration

Alexander Bukreyev 1 collaboration

Jay W Hooper 1 collaboration

James E Crowe 1 collaboration