Pascal Deschatelets

Affiliations

Apellis Pharmaceuticals, Waltham, Massachusetts, USA.

Publications (11)

C3 inhibition with pegcetacoplan in subjects with paroxysmal nocturnal hemoglobinuria treated with eculizumab.

American journal of hematology

Avec: Carlos de Castro , Federico Grossi , Ilene Ceil Weitz , Jaroslaw Maciejewski , Vivek Sharma , Eloy Roman , Robert A Brodsky , Lisa Tan , Carl Di Casoli , Delphine El Mehdi , Pascal Deschatelets , Cedric Francois

Pegcetacoplan controls hemolysis in complement inhibitor-naive patients with paroxysmal nocturnal hemoglobinuria.

Blood advances

Avec: Raymond Siu Ming Wong , Juan Ramon Navarro-Cabrera , Narcisa Sonia Comia , Yeow Tee Goh , Henry Idrobo , Daolada Kongkabpan , David Gómez-Almaguer , Mohammed Al-Adhami , Temitayo Ajayi , Paulo Alvarenga , Jessica Savage , Pascal Deschatelets , Cedric Francois , Federico Grossi , Teresita Dumagay

Inhibition of C3 with pegcetacoplan results in normalization of hemolysis markers in paroxysmal nocturnal hemoglobinuria.

Annals of hematology

Avec: Raymond S M Wong , Humphrey W H Pullon , Ismail Amine , Andrija Bogdanovic , Pascal Deschatelets , Cedric G Francois , Kalina Ignatova , Surapol Issaragrisil , Pimjai Niparuck , Tontanai Numbenjapon , Eloy Roman , Jameela Sathar , Raymond Xu , Mohammed Al-Adhami , Lisa Tan , Eric Tse , Federico V Grossi

Pegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS): 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial.

The Lancet. Haematology

Avec: Régis Peffault de Latour , Jeff Szer , Ilene C Weitz , Alexander Röth , Britta Höchsmann , Jens Panse , Kensuke Usuki , Morag Griffin , Jean-Jacques Kiladjian , Carlos M de Castro , Hisakazu Nishimori , Temitayo Ajayi , Mohammed Al-Adhami , Pascal Deschatelets , Cedric Francois , Federico Grossi , Antonio M Risitano , Peter Hillmen

Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria.

The New England journal of medicine

Avec: Peter Hillmen , Jeff Szer , Ilene Weitz , Alexander Röth , Britta Höchsmann , Jens Panse , Kensuke Usuki , Morag Griffin , Jean-Jacques Kiladjian , Carlos de Castro , Hisakazu Nishimori , Lisa Tan , Mohamed Hamdani , Pascal Deschatelets , Cedric Francois , Federico Grossi , Temitayo Ajayi , Antonio Risitano , Régis Peffault de la Tour

Inside-Out of Complement in Cancer.

Frontiers in immunology

Avec: Martin Kolev , Madhumita Das , Monica Gerber , Scott Baver , Pascal Deschatelets , Maciej M Markiewski

With complements: C3 inhibition in the clinic.

Immunological reviews

Avec: Martin Kolev , Tara Barbour , Scott Baver , Cedric Francois , Pascal Deschatelets

Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial.

Ophthalmology

Avec: David S Liao , Federico V Grossi , Delphine El Mehdi , Monica R Gerber , David M Brown , Jeffrey S Heier , Charles C Wykoff , Lawrence J Singerman , Prema Abraham , Felix Grassmann , Peter Nuernberg , Bernhard H F Weber , Pascal Deschatelets , Robert Y Kim , Carol Y Chung , Ramiro M Ribeiro , Mohamed Hamdani , Philip J Rosenfeld , David S Boyer , Jason S Slakter , Cedric G Francois

Pre-existing humoral immunity and complement pathway contribute to immunogenicity of adeno-associated virus (AAV) vector in human blood.

Frontiers in immunology

Avec: Corinne J Smith , Nikki Ross , Ali Kamal , Kevin Y Kim , Elizabeth Kropf , Pascal Deschatelets , Cedric Francois , William J Quinn , Inderpal Singh , Anna Majowicz , Federico Mingozzi , Klaudia Kuranda

Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials.

Lancet (London, England)

Avec: Jeffrey S Heier , Eleonora M Lad , Frank G Holz , Philip J Rosenfeld , Robyn H Guymer , David Boyer , Federico Grossi , Caroline R Baumal , Jean-Francois Korobelnik , Jason S Slakter , Nadia K Waheed , Ravi Metlapally , Ian Pearce , Nathan Steinle , Anibal A Francone , Allen Hu , David R Lally , Pascal Deschatelets , Cedric Francois , Caleb Bliss , Giovanni Staurenghi , Jordi Monés , Rishi P Singh , Ramiro Ribeiro , Charles C Wykoff , Auteur inconnu

Navigating the Complement Pathway to Optimize PNH Treatment with Pegcetacoplan and Other Currently Approved Complement Inhibitors.

International journal of molecular sciences

Avec: Peter Hillmen , Regina Horneff , Michael Yeh , Martin Kolev , Pascal Deschatelets

Réseau de co-auteurs

Cedric Francois 7 collaborations

Federico Grossi 5 collaborations

Lisa Tan 3 collaborations

Mohammed Al-Adhami 3 collaborations

Temitayo Ajayi 3 collaborations

Peter Hillmen 3 collaborations

Martin Kolev 3 collaborations

Carlos de Castro 2 collaborations

Eloy Roman 2 collaborations

Delphine El Mehdi 2 collaborations

Cedric G Francois 2 collaborations

Federico V Grossi 2 collaborations

Jeff Szer 2 collaborations

Alexander Röth 2 collaborations

Britta Höchsmann 2 collaborations

Jens Panse 2 collaborations

Kensuke Usuki 2 collaborations

Morag Griffin 2 collaborations

Jean-Jacques Kiladjian 2 collaborations

Hisakazu Nishimori 2 collaborations

Mohamed Hamdani 2 collaborations

Scott Baver 2 collaborations

Jeffrey S Heier 2 collaborations

Charles C Wykoff 2 collaborations

Philip J Rosenfeld 2 collaborations

Jason S Slakter 2 collaborations

Ilene Ceil Weitz 1 collaboration

Jaroslaw Maciejewski 1 collaboration

Vivek Sharma 1 collaboration

Robert A Brodsky 1 collaboration

Carl Di Casoli 1 collaboration

Raymond Siu Ming Wong 1 collaboration

Juan Ramon Navarro-Cabrera 1 collaboration

Narcisa Sonia Comia 1 collaboration

Yeow Tee Goh 1 collaboration

Henry Idrobo 1 collaboration

Daolada Kongkabpan 1 collaboration

David Gómez-Almaguer 1 collaboration

Paulo Alvarenga 1 collaboration

Jessica Savage 1 collaboration

Teresita Dumagay 1 collaboration

Raymond S M Wong 1 collaboration

Humphrey W H Pullon 1 collaboration

Ismail Amine 1 collaboration

Andrija Bogdanovic 1 collaboration

Kalina Ignatova 1 collaboration

Surapol Issaragrisil 1 collaboration

Pimjai Niparuck 1 collaboration

Tontanai Numbenjapon 1 collaboration

Jameela Sathar 1 collaboration

Raymond Xu 1 collaboration

Eric Tse 1 collaboration

Régis Peffault de Latour 1 collaboration

Ilene C Weitz 1 collaboration

Carlos M de Castro 1 collaboration

Antonio M Risitano 1 collaboration

Ilene Weitz 1 collaboration

Antonio Risitano 1 collaboration

Régis Peffault de la Tour 1 collaboration

Madhumita Das 1 collaboration

Monica Gerber 1 collaboration

Maciej M Markiewski 1 collaboration

Tara Barbour 1 collaboration

David S Liao 1 collaboration

Monica R Gerber 1 collaboration

David M Brown 1 collaboration

Lawrence J Singerman 1 collaboration

Prema Abraham 1 collaboration

Felix Grassmann 1 collaboration

Peter Nuernberg 1 collaboration

Bernhard H F Weber 1 collaboration

Robert Y Kim 1 collaboration

Carol Y Chung 1 collaboration

Ramiro M Ribeiro 1 collaboration

David S Boyer 1 collaboration

Corinne J Smith 1 collaboration

Nikki Ross 1 collaboration

Ali Kamal 1 collaboration

Kevin Y Kim 1 collaboration

Elizabeth Kropf 1 collaboration

William J Quinn 1 collaboration

Inderpal Singh 1 collaboration

Anna Majowicz 1 collaboration

Federico Mingozzi 1 collaboration

Klaudia Kuranda 1 collaboration

Eleonora M Lad 1 collaboration

Frank G Holz 1 collaboration

Robyn H Guymer 1 collaboration

David Boyer 1 collaboration

Caroline R Baumal 1 collaboration

Jean-Francois Korobelnik 1 collaboration

Nadia K Waheed 1 collaboration

Ravi Metlapally 1 collaboration

Ian Pearce 1 collaboration

Nathan Steinle 1 collaboration

Anibal A Francone 1 collaboration

Allen Hu 1 collaboration

David R Lally 1 collaboration

Caleb Bliss 1 collaboration

Giovanni Staurenghi 1 collaboration

Jordi Monés 1 collaboration

Rishi P Singh 1 collaboration

Ramiro Ribeiro 1 collaboration

None None 1 collaboration

Regina Horneff 1 collaboration

Michael Yeh 1 collaboration